XLOC_001933 (ndufa8)


Basic Information

Item Value
gene id XLOC_001933
gene name ndufa8
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 9410304 ~ 9419994 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00003794
TCTACGTACATGCGCAGTAAACTGACCTTCTCTGCGCGGCCTCGTCCTACTGCCGACGAGGACATTGACCCGTTTTAAAGTGTGGACTGTTAAAATAATTGTGGTTAGTTTTGGTGCATTAAACTCGCACCATGCCCGGTGTGGTTGAGATTCCGACGTTGGAGGAATTAAACGTCAAAGAGGTGAATGTATCGTCTGCTGTACTGAAGGCGGCTGCTCATCACTTTGGCTCTCAATGTGACAAGCCCAGCAAAGAGTTCATGTTGTGCCGGTGGGAAGAGAAGGACCCTAGAAAGTGTTTGGAAGAAGGGAGGAAAGTCAATGAGTGTGCTGTCAACTTCTTCAGGCAGATAAAGGGAAACTGCGCTGAGTCCTTCACAGATTATTGGACCTGTCTGGATTACTCTAACATGGGTGAGCTGCGCCGCTGCCGTAAACAGCAGCATGAGTTTGATAACTGTGTGCTGGACAAACTGGGATGGAAGAGACCTGAGCTTGGAGAACTGTCTAAAGTGACCAAGGTGCAAACCGCTCGACCCTTGCCTGAAAATCCCTACCATTCTAGACCAAGACCCGAGCCCAACACTCCAATTGAGGCTGAACTACAACCGGCTAAGCATGGCAGCCGCTTGTTCTTCTGGAACTGGTAAAAAGAGTCTACCACTGTCCTATAAATAGCATGTTCTTCATCTACATGCTCCTGATGGGACGTAAGACAGTGTGCCAATGGTTGCGCTGTTATCCTAATGTGTTGTGTagaaatgtttataaattttGTTCTTCAAttaaaaagatttaatttaaa

Function

symbol description
ndufa8 Predicted to act upstream of or within mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane; mitochondrial intermembrane space; and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in several structures, including alar plate midbrain region; liver; optic tectum; optic vesicle; and retina. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Orthologous to human NDUFA8 (NADH:ubiquinone oxidoreductase subunit A8).

GO:

id name namespace
GO:0006120 mitochondrial electron transport, NADH to ubiquinone biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0005743 mitochondrial inner membrane cellular_component
GO:0005747 mitochondrial respiratory chain complex I cellular_component
GO:0016020 membrane cellular_component
GO:0070469 respirasome cellular_component
GO:0005739 mitochondrion cellular_component

KEGG:

id description
ko00190 Oxidative phosphorylation
ko04723 Retrograde endocannabinoid signaling
ko04714 Thermogenesis
ko05208 Chemical carcinogenesis - reactive oxygen species
ko05010 Alzheimer disease
ko05012 Parkinson disease
ko05014 Amyotrophic lateral sclerosis
ko05016 Huntington disease
ko05020 Prion disease
ko05022 Pathways of neurodegeneration - multiple diseases
ko05415 Diabetic cardiomyopathy
ko04932 Non-alcoholic fatty liver disease

ZFIN:

id description
ZDB-GENE-040426-1688 Predicted to act upstream of or within mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane; mitochondrial intermembrane space; and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in several structures, including alar plate midbrain region; liver; optic tectum; optic vesicle; and retina. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Orthologous to human NDUFA8 (NADH:ubiquinone oxidoreductase subunit A8).

Ensembl:

ensembl_id ENSDARG00000058041

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00003794 True 805 mRNA 0.46 4 9410304 9419994

Neighbor

gene id symbol gene type direction distance location
XLOC_001932 lhx6 coding upstream 15084 9372702 ~ 9395220 (+)
XLOC_001931 rbm18 coding upstream 39360 9346383 ~ 9370944 (+)
XLOC_001930 slc37a4b coding upstream 125130 9281991 ~ 9285174 (+)
XLOC_001929 paqr3b coding upstream 174858 9222476 ~ 9235446 (+)
XLOC_001928 antxr2b coding upstream 190641 9195190 ~ 9219663 (+)
XLOC_001934 si:ch211-243g18.2 coding downstream 130425 9550419 ~ 9571012 (+)
XLOC_001935 rc3h2 coding downstream 175581 9595575 ~ 9661896 (+)
XLOC_001936 rabgap1 coding downstream 277103 9697097 ~ 9810597 (+)
XLOC_001937 CABZ01061749.1 coding downstream 305780 9725774 ~ 9725891 (+)
XLOC_001938 NA coding downstream 403203 9823197 ~ 9835446 (+)
XLOC_001926 NA non-coding upstream 284441 9122393 ~ 9125863 (+)
XLOC_001921 BX571955.2 non-coding upstream 541409 8862521 ~ 8868895 (+)
XLOC_001919 NA non-coding upstream 636645 8773436 ~ 8773659 (+)
XLOC_001917 NA non-coding upstream 694556 8709485 ~ 8715748 (+)
XLOC_001913 NA non-coding upstream 759449 8646959 ~ 8650855 (+)
XLOC_001939 NA non-coding downstream 470697 9890691 ~ 9895543 (+)
XLOC_001940 BX248503.1 non-coding downstream 493069 9913063 ~ 9913177 (+)
XLOC_001941 AL935269.1 non-coding downstream 758107 10178101 ~ 10195602 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G420969 NA non-coding CI01000304 null 5824182 ~ 5828278 (+)