XLOC_019563 (skp2)


Basic Information

Item Value
gene id XLOC_019563
gene name skp2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007132.7
NCBI id CM002905.2
chromosome length 45934066
location 22347120 ~ 22359336 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00038528
ACATCACCTCCGGCAACCCACATTGCAACCAATAGTATCGCAGCAGGACAGGCGGTCTAGAGGCAGGTTTAAATGCGCCGCCAGCCTGATGCCTTGCTTCATTTGAAAGTTTGCAACACCcaacacttttattaatattacaagtCAGGATGTCAAACGAAAGGGTGTTTCAGGAGCTGAGTGAGAATTTGGAGGGGTCTCTGTGCAGGTCTCAGAGGACTAAGTGGAAAAAGCGGCCATCATGCAGCTCGGGTCTGGACACCGAAAACACCCCGAACGAGCTCATCCAGCAGTGGTCACCGCCGCACAAGAAGGCCCTGACTACTGCTAAAGGGAAAGAAAATGAGGAAAACCTGTTTGTGCTCGCCAGACGGCCCAGAAAAAGAAGAGAGTCATCAGCAAACTTGTGTTGGGACAGTCTACCCGACGAGCTGCTGCTGGGAATCTTTTCTCGTCTCTCACTGCAAGATCTTCTCAGGACGTCACGGGTGTGCAAGCGCTGGCATCGTTTAGCGTTTGATGAGTCTCTATGGCACAGTGTGGATCTGGTGGGAAAGGCTCAGCTGGATGCTGAGCTTGGTCAGGTTCTGTCAGCTGGAGTCCTGAGGTTGCGCTGTCCACACACCTGCATCGGCCAGCCCAGCTTTAAAAGCACACCGAGTCTTCGTGTCCAGCATCTGGATTTCTCAAACTGTACAGTAGAGACGTCTGTTCTTGAAGACGTCCTGTCACGCTGCAAACATCTTCAGAATCTCAGTCTTGAAGGATTGGTGCTCTCTGACAACATTATTTATTCTCTCGCTCAAAATCCTGAGATTATCCGGCTGAATTTATGTGGCTGTTCTGGCTTCTCCCCTGAATCTCTGACTGAGATGCTGACAGCTTGCACTCGaattgaagaaatgaacgTGTCGTGGTGTGACTTCAGCAATCTTCATATTCAAGCCATTGCCAGCAACATTCCCTCAAGCGTCTCTCAGCTGAACATCAGTGGTTATAGACAAAACCTCACAATGGAAGATGTCAAAGCTATAGTAAAAAGATGTCCAAACATCACAGACCTAGATTTAAGTGACAGTGTGCTTGTGACGACGGACAGTTTtcctgtcctgcagcagctttCCTCACTCAGACATCTGGGACTGAGCCGTTGTTATCAGATCCACCCAGCTTCTCTCATCGACTTTGAAAAGTTTCTGAATCTGCAGACCCTGGAGGTGTTCGGCCTCATTCAGGACAGTTACCTTCCCATTCTCTGTAAAAGCCTGCCGCACATCCAGATCAACACGCAGCCGTTCTCCACTGTGGCACGTCCCACCTCGTCCTCACGGAAAGACCGCACACTGTGGGGAATGCACTGCAGACTCGTCTACAAACATTAATGCTTTTAATCCAACATCATTACAAGGGAAACCAAACTGTGTTGTCTTTTAATAATAGTCCAGATCTCTCTCCTTGCGCCCAATTACAATTGTGATTTTAAAGAAACGTCTCAAACATCACTGTTATTTCCTGTCCTTTTATATTGTGAACGTGACAATTGTGTTGGAGATCCTGACAATCTTGAATTGAATGGTGATCTTGTTTATAAAATAAGGTATGAACAGAGAACAAGATTGCTAGATGTTTTATCTTGCAATGTTTGGTACAAATCATTTTGAAATCCAGAATGTTTCCAGTTTTACTCTAGGATTATCAAAGGACTAGTTTAGTATTAAGAAAAAGGTTTTATGCTTTTTATACTGTTCCTGAATTGAGTTCTGTGAAAGCATTACAGCAGCTGTTTCATAGAGGAGGAAATATTGTGAATCTCTTCCATTTCTCTGACCAGTTTTAATATCGAAGACTTGAATTTTTGTACAACATAGTTGTATTTTTATGAGCTGTTTACATCGTctgaattgtaaataaatgtattgctttttatttaaagtcatgtgAAAATCTTGTTCAGTGTTAAATTCATCGCATTGTGGTCTGTTAACACTTCAGATGTTACTCTCCGACATGTATAAATGTTGTGGTAGATTGCATAATgcagacaattttaaaaagcaccaatgtTTTACAAAATTGTGCCATATTTTGAGCCTCTTTTGCAGTATACCTTGACCTGATGGAGCAGAGTTTGACTCAATTCAAGCTCTATTctcagaaataaaatgtttttaaataacaa
>TCONS_00038529
CTAGTCGAATGTGCTGTTGGCGCGCGCCTGATGTCCTGTTGGGACGCGCGAGGATACATTTGCTCCACAAATCGGTGTTTCAGGAGCTGAGTGAGAATTTGGAGGGGTCTCTGTGCAGGTCTCAGAGGACTAAGTGGAAAAAGCGGCCATCATGCAGCTCGGGTCTGGACACCGAAAACACCCCGAACGAGCTCATCCAGCAGTGGTCACCGCCGCACAAGAAGGCCCTGACTACTGCTAAAGGGAAAGAAAATGAGGAAAACCTGTTTGTGCTCGCCAGACGGCCCAGAAAAAGAAGAGAGTCATCAGCAAACTTGTGTTGGGACAGTCTACCCGACGAGCTGCTGCTGGGAATCTTTTCTCGTCTCTCACTGCAAGATCTTCTCAGGACGTCACGGGTGTGCAAGCGCTGGCATCGTTTAGCGTTTGATGAGTCTCTATGGCACAGTGTGGATCTGGTGGGAAAGGCTCAGCTGGATGCTGAGCTTGGTCAGGTTCTGTCAGCTGGAGTCCTGAGGTTGCGCTGTCCACACACCTGCATCGGCCAGCCCAGCTTTAAAAGCACACCGAGTCTTCGTGTCCAGCATCTGGATTTCTCAAACTGTACAGTAGAGACGTCTGTTCTTGAAGACGTCCTGTCACGCTGCAAACATCTTCAGAATCTCAGTCTTGAAGGATTGGTGCTCTCTGACAACATTATTTATTCTCTCGCTCAAAATCCTGAGATTATCCGGCTGAATTTATGTGGCTGTTCTGGCTTCTCCCCTGAATCTCTGACTGAGATGCTGACA
>TCONS_00038530
CTAGAGGCAGGTTTAAATGCGCCGCCAGCCTGATGCCTTGCTTCATTTGAAAGTTTGCAACACCcaacacttttattaatattacaagtCAGGATGTCAAACGAAAGGGTGTTTCAGGAGCTGAGTGAGAATTTGGAGGGGTCTCTGTGCAGGTCTCAGAGGACTAAGTGGAAAAAGCGGCCATCATGCAGCTCGGGTCTGGACACCGAAAACACCCCGAACGAGCTCATCCAGCAGTGGTCACCGCCGCACAAGAAGGCCCTGACTACTGCTAAAGGGAAAGAAAATGAGGAAAACCTGTTTGTGCTCGCCAGACGGCCCAGAAAAAGAAGAGAGTCATCAGTCTACCCGACGAGCTGCTGCTGGGAATCTTTTCTCGTCTCTCACTGCAAGATCTTCTCAGGACGTCACGGGTGTGCAAGCGCTGGCATCGTTTAGCGTTTGATGAGTCTCTATGGCACAGTGTGGATCTGGTGGGAAAGGCTCAGCTGGATGCTGAGCTTGGTCAGGTTCTGTCAGCTGGAGTCCTGAGGTTGCGCTGTCCACACACCTGCATCGGCCAGCCCAGCTTTAAAAGCACACCGAGTCTTCGTGTCCAGCATCTGGATTTCTCAAACTGTACAGTAGAGACGTCTGTTCTTGAAGACGTCCTGTCACGCTGCAAACATCTTCAGAATCTCAGTCTTGAAGGATTGGTGCTCTCTG
>TCONS_00038531
GAAAGTTTGCAACACCcaacacttttattaatattacaagtCAGGATGTCAAACGAAAGGGTGTTTCAGGAGCTGAGTGAGAATTTGGAGGGGTCTCTGTGCAGGTCTCAGAGGACTAAGTGGAAAAAGCGGCCATCATGCAGCTCGGGTCTGGACACCGAAAACACCCCGAACGAGCTCATCCAGCAGTGGTCACCGCCGCACAAGAAGGCCCTGACTACTGCTAAAGGGAAAGAAAATGAGGAAAACCTGTTTGTGCTCGCCAGACGGCCCAGAAAAAGAAGAGAGTCATCAGGTTTGTGACAAATCAAACTTGTGTTGGGACAGTCTACCCGACGAGCTGCTGCTGGGAATCTTTTCTCGTCTCTCACTGCAAGATCTTCTCAGGACGTCACGGGTGTGCAAGCGCTGGCATCGTTTAGCGTTTGATGAGTCTCTATGGCACAGTGTGGATCTGGTGGGAAAGGCTCAGCTGGATGCTGAGCTTGGTCAGGTTCTGTCAGCTGGAGTCCTGAGGTTGCGCTGTCCACACACCTGCATCGGCCAGCCCAGC
>TCONS_00038532
ACCCATCTGAAGCACGTTGTGGTAAAAATTACCTCAGGAACTTGACACCTGCCTCAGAACAGCCCTCTGCTCCAAACGAGGGTGTTTCAGGAGCTGAGTGAGAATTTGGAGGGGTCTCTGTGCAGGTCTCAGAGGACTAAGTGGAAAAAGCGGCCATCATGCAGCTCGGGTCTGGACACCGAAAACACCCCGAACGAGCTCATCCAGCAGTGGTCACCGCCGCACAAGAAGGCCCTGACTACTGCTAAAGGGAAAGAAAATGAGGAAAACCTGTTTGTGCTCGCCAGACGGCCCAGAAAAAGAAGAGAGTCATCAG

Function

symbol description
skp2 Predicted to be involved in G2/M transition of mitotic cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; and regulation of cell cycle. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alar plate midbrain region; digestive system; intermediate cell mass of mesoderm; nervous system; and ventral mesoderm. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human SKP2 (S-phase kinase associated protein 2).

GO:

id name namespace
GO:0051726 regulation of cell cycle biological_process
GO:0000086 G2/M transition of mitotic cell cycle biological_process
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biological_process
GO:0019005 SCF ubiquitin ligase complex cellular_component
GO:0005829 cytosol cellular_component
GO:0005634 nucleus cellular_component

KEGG:

id description
ko04120 Ubiquitin mediated proteolysis
ko04068 FoxO signaling pathway
ko04150 mTOR signaling pathway
ko04110 Cell cycle
ko05200 Pathways in cancer
ko05203 Viral carcinogenesis
ko05222 Small cell lung cancer
ko05169 Epstein-Barr virus infection
ko04121 Ubiquitin system

ZFIN:

id description
ZDB-GENE-030219-158 Predicted to be involved in G2/M transition of mitotic cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; and regulation of cell cycle. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alar plate midbrain region; digestive system; intermediate cell mass of mesoderm; nervous system; and ventral mesoderm. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human SKP2 (S-phase kinase associated protein 2).

Ensembl:

ensembl_id ENSDARG00000004937

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00038528 False 2179 mRNA 0.43 10 22347120 22357985
TCONS_00038529 False 791 mRNA 0.52 6 22352310 22357545
TCONS_00038530 False 705 nonsense_mediated_decay 0.51 5 22353998 22357929
TCONS_00038531 False 553 nonsense_mediated_decay 0.52 4 22354223 22357881
TCONS_00038532 True 316 processed_transcript 0.53 2 22356807 22359336

Neighbor

gene id symbol gene type direction distance location
XLOC_019562 NA coding downstream 19484 22325627 ~ 22327636 (-)
XLOC_019561 gdpd4b coding downstream 21996 22311964 ~ 22325124 (-)
XLOC_019560 ompb coding downstream 157401 22188010 ~ 22189719 (-)
XLOC_019559 slc35f2 coding downstream 224808 22115806 ~ 22122312 (-)
XLOC_019558 elmod1 coding downstream 231928 22099300 ~ 22115192 (-)
XLOC_019564 NA coding upstream 2698 22362034 ~ 22375102 (-)
XLOC_019565 CU466287.1 coding upstream 11694 22371030 ~ 22371136 (-)
XLOC_019566 NA coding upstream 25791 22385127 ~ 22399013 (-)
XLOC_019567 il7r coding upstream 70173 22429509 ~ 22435957 (-)
XLOC_019568 myo5b coding upstream 86904 22446240 ~ 22547496 (-)
XLOC_019557 NA non-coding downstream 265066 22073949 ~ 22082054 (-)
XLOC_019538 NA non-coding downstream 921609 21405218 ~ 21425511 (-)
XLOC_019535 NA non-coding downstream 1168369 21162410 ~ 21178751 (-)
XLOC_019534 NA non-coding downstream 1187725 21157734 ~ 21159395 (-)
XLOC_019596 NA non-coding upstream 756008 23115344 ~ 23132318 (-)
XLOC_019597 NA non-coding upstream 786955 23146291 ~ 23154522 (-)

Expression


Co-expression Network