XLOC_002107 (kdm6bb)


Basic Information

Item Value
gene id XLOC_002107
gene name kdm6bb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 22724059 ~ 22760659 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004096
ggaaaagagaGGAGAAAGAGGGAGGAGAGAAGTGGGGAACAGAGGCGACAGGATTGACTCGGGAGGGAGAGGAAAGGAATTGCTTTGAGGGGAAAAGAAGGAAAAATAGGAGCAAGAGGGGAAGAGAAGAGGTGAAAGTAGAGGAGAGGAGAAAAGCTTGAACTGAAAGCGAAGGAAAGTATAGTGATCTCTGTTGAGATCTGCAGTGGAGGGTTTCTCAGACTCATCAGCGTGGCTGAATGTACCACATAGCAGAGCAGTATTCTGGACGTAACTCGTGGGACTCCTTCCCCTCTTCTGGGCCGAATCGAGCACCATGGGCCCCAGGCAACAACCGGCACTGGGCCCCTCCATCCAGCGGAGGGAACTATCAATCCCCATCACAAAACTACATGGCAGGAAGAAGCTACCCAAACAAAGCTTATAACAACAGACCTCCAGGTTTCAGCAGGGACAGACTCCATGCTCACCCCAGAGACCGAGGCAATGGAAAGGAGCAGAGGGTTCCTAGGAGCTGTGGACCAACCCAGAACCAGCACCACAACCCAGAACGCTCTACCCTAAACTACAGCTCAGGGTATGAAGGACACCTCTCTAGCAGTAACAATCATGGCAACCAGCCACACAGGTATGGGGGTCCGCACCAGCAGCAGCGTTCCACTGGGCGCCCCCCACAGacccagggagagaagtggacacATTCAGCTCAATCCAGGTCTTTCCAAGGGCCCTCTCTCAAACGTCCAGTACCTCCTCACAATCTCTCACAACCCCTCCGTGAACCGTCCCCTTCACGAGATGACTGTCCTAGCAAGAGGAGTAGGAGCATCAACTCACACCAGAATTTCCACCCTAGAGACAAATATTTCATCAACCGTCCACCTCCATCTCATCCACCTCGTCCCTGGAGCCCAGCATACAAAAGCTCAATGTCCTGGAGCCTGTCTGAGAAGAGGTCCTCCCCCTCCCGCTTTCAGGAGTCCAGTCATTCAGTCACAAGAGATCACACCTATAGACCATATTCCCACTCATCACCACCCAGCAGTGTCCCAAACCAGGGCCTCCACAACAGGAAACTCACCAAACAAGGGCCCGCCCATCATCCGGtccatgatcatccagactcccCTCCCCGCGGGGCAAAAGGGGGCTGGGATTGCCCATCACCAGCAAACCTCACTGTGCCTTACAGTCAGCAGCACCAGCTCCCTCCACCACAGAGGCACACCGGCCCCTCCAGCAGCCCAGCCACCTCAGTACCTCAACCCAGATCCAACACAGCACAGCATGGCTGGAAAACGCAGAACCGCTCTGGAAAACACAGTAACAGCGAGATGGGCCGTACAACCTATGAACTGGACTCCCATCAGTCTGTGGGTGGGGACAGAAAACGATCAAGCGGATCCAAACACATTAGCCGTCAACGAAGTCCTATCCAACCATACAACAGTGCTGAGGGTAGAGTCAGAGATTGTACTGAATGGAGGAACCCAGAGACTGGGTTAAAGAAACATGACCAGAAAGACTCAGACTCTCCTTCTGAGCCTACCACTCAAACCTCAGAAAGAGGTCAGAGGGCACAGAGGTCAGAAATGAAGAAAAGCAGGCACTCTAAACACCAGAATAAATTAAAATCCACCCACAAGAGTGCCCTCAGCAAGCTGGACtctgaactcttgaaacacattCAGGCCAAGAAGAGGCACAAGGAGCGTTTGAGGAGGAAGCAGAAAAAGGAGGAAGGAGAACTGACAGAAGACACAAAGGAACGGATAGAGAAAAAAATAgaagaaaggaaaaagaaaaagacgAGGGAAGGAAGAAAAGGCCATGATAAGAAAACCATACATAAAAGTGGGAGAAAGTTAGGGCAGgttaaaaaaagagcaaaagagGAAAGAAAACAAGGAGACAGAAAAAGTGAGACATCCATTTCAAAAACAGCATCTCCTAATTTGGGAACTTTGTATCCCAGTGATTCTGATCCTCTCTTGGATGACCTGCTGGCTGATCCACTTCATCTCAGTTACATAGAGGAAGAGAACGAGTTCTCTCAACATACCTCAGGGTTCATCCTACCTTGTAAATCTCCTGTCAACAATAACCATTGTTCTCCATGCCAATCAACCCTTGAAATCAATACTAAAGTCTTGGAGGTTGATGAAAAGTCAGATTCTGAGCCTGACCATGTAGACACTAGCGATGATGACAGTGTAGGAACCCATGATGTTAGTGGATCCAATCCCTCTCTTCTTAATACACATGTCTCTGAAGAAGAACCCATCAGATGCAAGGAGGTTGTCCCAGGGTTGCATACTGCTCCAGACCTCCTACCGGCTCACTGCACCTATAGCGAGGAACTCCTAAGGTTGGACCCACCTACAAGCCCACCTGTTTTAAGCTGGCAGGGTTCTCCTGTTTTAGACTTgggtgatgatgatgaggatgtgAAAGAAGAAGATATGATTGGAGTGTTGAGAAGGCCAGTGCTTCAACCTAGTCCCACACACTCATCTCCACTTAGAGAAGCAATTGAAATCAGCACTGGGGTTGATTATTGCCACAGTGACCTGGCCAAGTTGTATGGACTTCCTGAGTCCTCTAAAGCAATGGACActgaggaggaggatgaagaaaAGACAGATGGGGAGCAAAAAGATGGTAGTCCTGATGCATCAGGAAGTTCTGAGACCAACAAACCACATTTGCACCAAATGGACACATTCAAATCTCCATCCTCAGCAATGGCCAGCCATAGATATACTTATAGGGGTGGGCCATTTGGTCGGCCACCCCCTAGTGCTTTAGTTGGGGTCAAATACTCCTCATCTCTGTCCTTGGGTCCTGAGATCCACCCACCAGACCAGCAGAGTCCACCTGCCTCATCCCCAACCACAGAGATTCCAGATCAGGTTATACATTCGCTGATCCAGCCCACAGACAAGGACAAAGAAAGTGAAACAGAAGAAGAAATAATGAAAACTGGGGCAAAAGAGGACAAAATAGAAGTAAAAGGAGAGGAAACTAAGGTACAGAAGATGGATGAACAAATGGAGGTAAAATTAGCCGAACCAACTAAAGACCCAGCCAGCACATCACTGGAAGAGAAAGAATCTGTGATGTCTCCAGCCACTGTTCAAGCTAAACTTGTACACAGCTGTGAACTACTGCTCAATCAAAACTCCAGCCCAGTGTCAAAGGTCATGAAAGTCAGTGGATCCAAGTCTGATCAGAGAGAAAATgaaggagacagacagaaagatcaGTTGAAGACTCCAAGAAAAGCGATTAGGACCATGAAAGAAGAAGAACCTGAAACTTGTGTTGGTAGAAGCATTAAAGCAAAACATCATAAAAAAGGTGACAGAGGAGAGAATAAAAAGGACATAATGAAAGATAAGGCTGAGACAAATTCTTCTTCTTTGTCTTCTGAAGATGCACAGAAGCAATTGGTGGAAATCAGGACCAAACAAGTTGTCCCAGAAAACCAACAAATTGAAATCAAAGTTGGAAAAACCGAATCTCATAAAATTaagagagaaaaagagacagATGTTAAAAAAGATGCCATAAAAGAAGACGCTATTAAGGCTGATTCATCCGCTACAGGATGTACATCTTGCACAACTAACCTGCAATCCTCTAGTACTATGACTCTCTTCACCAGACCACCAATGCTGGAGCGGGTAAATCTCCGAAATCAACACGAGCTCTCTAAAATTCCCTTAAAAGAACTAAAGATCTGTTTGGTCAAGATTGAGAGCAGAGGTCGGCAGACTTTCAGAGCCTCAGAGATTGAGGAGAAAAGCATTCCACTTGATGCCATCAACATCAGAAACAATGCAGCCGAGGTCATACGAGCTTGCAAAGGGGCAGACATCAAGAACAAGTTTCGTGAATCATACCTGCTCCCGTCGCTTTCAGTGAAACCTGACCTGTCATGCAGGACCCCAATTCCCAGAGATAAACTGAACCCTCCTACACCAAGCATTTATctGGAGAGTAAAAGGGATGCTTTCTCTCCCGTGCTCCTGCAGTTCTGCACGGACTCTAAAAATGCAGTTACTGTAATCAGAGGACTGGCTGGATCCCTCCGTCTCAATCTGGGTTTGTTCTCCACAAAATCTCTGGTGGAAGCCAACTCTGAGCATGCAGTGGAGGTGAGGACCCAGGTGCAGCAGCCTGCAGATGAGAACTGGAACCATTCAGGATCCGCCCAGACTTGGCCCTGCGAAAGTAGCAGATCTCACACCACCATTGCTAAATACGCACAGTATCAAGCATCCAGTTTCCAGGAGAGCCTACAAGAAGAGAAAGACAGtgaagatgaagatgaggaaGACAAATCAAAGGAAAAAAATGAGGCAAAATCCAACTCACAAAACAACATTGGGACAACTTCAACCACAACCAGCTCAAAGCAGAAAGCTGTTGGGAAAATTATTAAATTTGGAACCAACATTGACTTATCTGACCCAAAACGGTGGAAGGCGCAGTTGCAGGAGCTGTTGAAGTTGCCTGCGTTCATGCGTGTGTCCTCCACCGCAAACATGCTGAGTCATGTTGGCCACACTATACTGGGCATGAACACTGTTCAGCTTTATATGAAGGTCCCTGGCAGCCGCACACCAGGACATCAGGAAAATAATAACTTCTGTTCAGTGAATATCAATATTGGCCCTGGTGACTGTGAATGGTTTGCTGTCCATGAACACTACTGGAAAGCCATCAGTGACTTCTGTGAAAAGCATGGCGTGGACTATCTGACAGGGTCATGGTGGCCGGTTCTGGAGGACCTTTACCGTTCCAACATCCCTGTGTACCGCTTCATTCAGAGGCCAGGTGACCTGGTGTGGATCAACGCTGGCACTGTGCACTGGGTCCAGGCTGTGGGCTGGTGCAACAACATCGCCTGGAATGTGGGCCCTTTAAATGCCTATCAATACCAGCTAGCTCTTGAGCGCTTTGAATGGAACGAGGTCAAGAAGGTCAAATCAATCGTCCCTATGATTCACGTGTCCTGGAACGTTGCCCGCACAATCAAAATCACAGACCCAAACACATTCAAGATGATCAAACATTGTCTCATGCAGTCCATCAAACACATTCAGATCTTGAGGGACCAGCTGGTGTCTGCAGGGAAGAAGATCTCCTATCAGAGTAGGGTGAAGGATGAACCGGCGTATTACTGCAATGAGTGTGATTTGGAGGTGTTTGACCTGCTGTTTGTGACTAGTGAGAACAGCAGTAGGAAAACATATGTGGTTCACTGTGAGGACTGCGCTCGGGAACGAAGCCCCGGTCTGAACGGGGTGGTGGTGCTGGAGCAGTACCGCATCGATGAGCTGATGAACATGTATGATAACTTTACCCTGTCTGCAGTTCCATGCTGTAGGTGAGCTTGATGTCTGAAATTACACAGCCATAACCAAATCTCCCACCCTCCTGCCCCAAAGCAGCGGCACAAACCTTCTGttctcctttattttattttcatttcctaCCAAAACCACTACTGCAGACTTACGGAACAGCAGATCAAACCGCTGTTTACTTCACATTGTTTACAATCCTATCAGCAGATGTCGTCTTCCCTCAGCCAGAAACTGACGGGACATCTGAGTCTAGAAAGACTAGAGTGGTGCTACATCATTGGACTCGAACAATAATCTTGTAACTTGGCTATCAGGTCACTCATCCACAACGGATAACTGCTgtgattttcctttttaaaatgaaaaaaatggagaaaaaaaaaacaattgtcaacTTGCCGAACACGTGCATTAATTCAGGTACTGATGTAGTTTACTTTTTTATGCAAACGGAAGACGATTTCACCAGTCCAGTTATACTCTATGTCTCTGGTTTATCTGAGTGGTGCTTTGATACAACGTATATAAAAACAGCAGGGGATTCATTTCTCTTGGCGCTGATGACCATTGCAGTGGCATTACATTTATTCTTAgtttgtttcgttttgttttag

Function

symbol description
kdm6bb Enables H3K27me3 modified histone binding activity and histone demethylase activity (H3-K27 specific). Acts upstream of or within several processes, including common myeloid progenitor cell proliferation; fin regeneration; and primitive erythrocyte differentiation. Predicted to be located in nucleus. Predicted to be part of MLL3/4 complex. Is expressed in brain; caudal hematopoietic tissue; heart; otic vesicle; and spinal cord. Orthologous to human KDM6B (lysine demethylase 6B).

GO:

id name namespace
GO:0030099 myeloid cell differentiation biological_process
GO:0061384 heart trabecula morphogenesis biological_process
GO:0002262 myeloid cell homeostasis biological_process
GO:0071557 histone H3-K27 demethylation biological_process
GO:0007507 heart development biological_process
GO:0031101 fin regeneration biological_process
GO:0035726 common myeloid progenitor cell proliferation biological_process
GO:0060319 primitive erythrocyte differentiation biological_process
GO:0044666 MLL3/4 complex cellular_component
GO:0005634 nucleus cellular_component
GO:0031490 chromatin DNA binding molecular_function
GO:0043565 sequence-specific DNA binding molecular_function
GO:0071558 histone demethylase activity (H3-K27 specific) molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003682 chromatin binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0061628 H3K27me3 modified histone binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040724-166 Enables H3K27me3 modified histone binding activity and histone demethylase activity (H3-K27 specific). Acts upstream of or within several processes, including common myeloid progenitor cell proliferation; fin regeneration; and primitive erythrocyte differentiation. Predicted to be located in nucleus. Predicted to be part of MLL3/4 complex. Is expressed in brain; caudal hematopoietic tissue; heart; otic vesicle; and spinal cord. Orthologous to human KDM6B (lysine demethylase 6B).

Ensembl:

ensembl_id ENSDARG00000056929

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004096 True 5989 mRNA 0.47 21 22724059 22760659

Neighbor

gene id symbol gene type direction distance location
XLOC_002106 NA coding upstream 102768 22620330 ~ 22621291 (+)
XLOC_002105 efnb3a coding upstream 117591 22536693 ~ 22606468 (+)
XLOC_002104 gigyf1b coding upstream 190266 22510280 ~ 22533793 (+)
XLOC_002103 nlgn2b coding upstream 245930 22381802 ~ 22478129 (+)
XLOC_002102 NA coding upstream 347031 22373301 ~ 22377028 (+)
XLOC_002108 tmem88a coding downstream 10517 22771176 ~ 22780157 (+)
XLOC_002109 si:ch211-237l4.6 coding downstream 21863 22782522 ~ 22786450 (+)
XLOC_002110 NA coding downstream 73652 22834311 ~ 22838481 (+)
XLOC_002111 AL807389.1 coding downstream 86613 22847272 ~ 22847404 (+)
XLOC_002112 ap4m1 coding downstream 94144 22854803 ~ 22862078 (+)
XLOC_002101 NA non-coding upstream 444611 22275913 ~ 22279448 (+)
XLOC_002100 NA non-coding upstream 450197 22253344 ~ 22273862 (+)
XLOC_002099 NA non-coding upstream 460794 22224203 ~ 22263265 (+)
XLOC_002116 FP102052.2 non-coding downstream 177572 22938231 ~ 22956370 (+)
XLOC_002117 NA non-coding downstream 199630 22960289 ~ 22965426 (+)
XLOC_002119 NA non-coding downstream 273670 23034329 ~ 23039290 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000304_10093597_10099497 KDM6BA, KDM6BB, KDM6B coding CI01000304 null 10093597 ~ 10099497 (+)
bowfin (Amia calva) AMCG00011621 NA misc CM030138.1 CM030138.1 1426201 ~ 1460034 (+)