XLOC_021201 (pdgfaa)


Basic Information

Item Value
gene id XLOC_021201
gene name pdgfaa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007133.7
NCBI id CM002906.2
chromosome length 39133080
location 25991130 ~ 26005894 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00041614
CACGCTCCGCTCCGCGCTTCAGGACCTGCTGAAGCTTCACCAGACACATTCTTTCATGAGGACACAACGTGGATGGTGCGTCAAATGGACTATTCTGGATAAACGTGGACTCTTTGATTATACTAACTCGTTTTTTCGTCTAGGAACATTTTTGGATTTAGATTTTGTATTATTCAAACACATTTCTGAAAAGATGCTATAAAAGGATGATATTTTAATGGATTAAAAGCGACAAGAAGTAATTAGAGTCGATTTTAGGACTTGCTTTTCTGTTTGACTTGTGAAGAGTTTATCCTTTGGGAGATTTGTCTGTAGAAAGGCATGTTCCCCGGCTCCCCGCCGGTTGGAGCATCTCTGCGGCTCCGGTCGGGACGGTTTCGCCTGCGCTGGGACACTTTTGGACCACAGGGGAGATGAGAACCGCGCTGATCCACTTTCTCGTCTGCTGCTTCTCTCTGCTTTCAGCAGCCGCTGAGgAAGCACCAATTCCCCGAGAGCTGATTGAGAGACTCTCTAACAGTGAGATCCACAGCATCAGCGACCTCCAGAGGATCCTGGAAATGGACTTCCTAGAGAATGAAGTGCTGGAGGATGTTAAACAAGGCCACCATAAGGAGCATCTGTACGACAGCAGAAACCTCAAGAACTTGCACTCCAGACGCAAGAGAAGCATTGAGGAGGCAGTGCCAGCCGTCTGTAAGACCCGTACGGTGATCTATGAGATCCCACGAAGTCAGGTGGATCCAACAGCCGCCAACTTCCTGATCTGGCCTCCGTGTGTGGAGGTGAGGCGATGCTCAGGCTGCTGCAACACCAGCAACATGCGCTGCCACCCGTCCAAAAAACACCACAGGAACGTGAAGgTGGCAAAGGTAGAGTATGTTCGACGGAGGCCGAAGCTGCGGGAGGTGCAGGTGCAGCTGGAGGATCATCTGGAGTGTGTTTGCACGTCCAGACATCACTCAGAGTCCCGCATACACACAGCAGATATAAGGTGAGCGTGGCACCAGATAAAAAAAAGGCAGAGGAGGGCATCAGATATCAGGCTGAACCACAGCCATTGACTGATAAAATCTGAAGACACTCTTCAACAGCGAGCCAATCAGGGCGCAGCTCTTGGATCACTCTGGACTTTTCATGCACCTTTAAAAGGAACCCAAACTTGTGGGTTTGGATAAAAACCCAGAGGGATTACACAATAGACTGCAACGACAGCCTGAAAAACGAACTCAGACTTCTGTCTCCACCGCCTTTTAAAGGAGAATCAATCATGACTTTATCTATCGAAATGTATATTTCTCCAGCAAATAACTGTATCATATTATTTTTGTAACTGTCCGTTTTCTATCGACACTGATCGTCTCTTGTATATATGCCGTAGAATGGACGAATGCAGCAAAACTCAATCTACAGTAACTCTTATACTAATAAAGCGAATACATTTTATTGTGTTTGTTTCTCAAA

Function

symbol description
pdgfaa Predicted to enable platelet-derived growth factor receptor binding activity. Acts upstream of or within with a positive effect on neural crest cell migration. Acts upstream of or within cardiac muscle progenitor cell migration to the midline involved in heart field formation. Predicted to be located in membrane. Predicted to be active in extracellular space. Is expressed in several structures, including anterior neural keel; chordo neural hinge; diencephalon; endoderm; and head. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human PDGFA (platelet derived growth factor subunit A).

GO:

id name namespace
GO:0007275 multicellular organism development biological_process
GO:0043406 positive regulation of MAP kinase activity biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:0048008 platelet-derived growth factor receptor signaling pathway biological_process
GO:0008284 positive regulation of cell population proliferation biological_process
GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation biological_process
GO:0031954 positive regulation of protein autophosphorylation biological_process
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling biological_process
GO:0030335 positive regulation of cell migration biological_process
GO:0005615 extracellular space cellular_component
GO:0016020 membrane cellular_component
GO:0005161 platelet-derived growth factor receptor binding molecular_function
GO:0070851 growth factor receptor binding molecular_function
GO:0008083 growth factor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030918-2 Predicted to enable platelet-derived growth factor receptor binding activity. Acts upstream of or within with a positive effect on neural crest cell migration. Acts upstream of or within cardiac muscle progenitor cell migration to the midline involved in heart field formation. Predicted to be located in membrane. Predicted to be active in extracellular space. Is expressed in several structures, including anterior neural keel; chordo neural hinge; diencephalon; endoderm; and head. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human PDGFA (platelet derived growth factor subunit A).

Ensembl:

ensembl_id ENSDARG00000110069

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00041614 True 1464 mRNA 0.47 6 25991130 26005894

Neighbor

gene id symbol gene type direction distance location
XLOC_021200 AL845363.1 coding downstream 184573 25806441 ~ 25806557 (-)
XLOC_021199 NA coding downstream 247339 25735181 ~ 25743791 (-)
XLOC_021197 NA coding downstream 377789 25606015 ~ 25613341 (-)
XLOC_021198 si:ch211-12h2.8 coding downstream 378450 25611415 ~ 25612680 (-)
XLOC_021196 CR769772.2 coding downstream 447931 25540945 ~ 25543199 (-)
XLOC_021202 pdgfaa coding upstream 79449 26085343 ~ 26100282 (-)
XLOC_021203 c3b.2 coding upstream 123356 26129250 ~ 26175237 (-)
XLOC_021204 c3b.1 coding upstream 174290 26180184 ~ 26236275 (-)
XLOC_021205 ccdc130 coding upstream 233530 26239424 ~ 26265355 (-)
XLOC_021206 wdr83 coding upstream 258649 26264543 ~ 26274177 (-)
XLOC_021194 NA non-coding downstream 457140 25498134 ~ 25533990 (-)
XLOC_021210 NA non-coding upstream 353668 26359562 ~ 26369942 (-)
XLOC_021211 NA non-coding upstream 373129 26379023 ~ 26383952 (-)
XLOC_021217 BX908757.3 non-coding upstream 638340 26644234 ~ 26644968 (-)
XLOC_021218 BX908757.2 non-coding upstream 643611 26649505 ~ 26650144 (-)
XLOC_021219 BX908757.1 non-coding upstream 660064 26665958 ~ 26666940 (-)

Expression


Co-expression Network