XLOC_002323 (nf1b)


Basic Information

Item Value
gene id XLOC_002323
gene name nf1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 37268854 ~ 37394957 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004425
TCGGCGTGAGCGGCCATGGCGGCGCAGAAGCCCGTGGAGTGGGTCCAGGCCGTCATCAGCCGATTCGACGAGCAGCTTCCTGTGAAAGTCGgtgttcaaaacacacacactaaaatcAGCACAGAACACAATAAGGAATGCCTGATCAACATCTCCAGGTACAAATTCTCCCTGGTCATCAGCGGACTCACCAACATACTGAAGAACGTCAACAACATGAGAATATTTGGAGATACTGCAGAGAGGAATCTTTACCTGTCACAGCTAATCATCTTGGACACATTGGAGAAGTGCTTGGCAGGGCAACCGAAAGACAGCATGCGTCTAGACGAGACGATGCTTGTGAAGCAGCTGTTGCCGGAGATCTGTCATTTCATCCACACGTATCGTGAGGGAAACCAGCACGCGGCTGAGCTGAGGAGCTCCGCCTGTGGTGTCCTGTTCTCTCTGAGCTGCAGTAACTTCAACGCCGTCTTCAGCCGCATCTCCACCAGGCTACAGGAGCTGACTGTCTGCTCGGAAGATACTGTGGACGTGCACGACATTGAGCTCATTCAGTACATCAATGTGGATGGCTGTAAACTCAAACGCCTCCTCCAAGAAACTGTCTTTAAATTTAAAGCCTTAAAGAAGCCGGCACAGTTAAGTGTCATCTTCAATTTAGAGAAGGCGTTTTGGAACTGGGTGGAGAATTATCCTGATGAATTCACCAGGCTGTACCAGAGGCCTCAAACAGACATGGCTGACTGTGCTGAAAAGCTGTTTGATCTGGTGGACAGTTTTGCCGAAAGCACGAAGAGAAAAGCAGCTGTTTGGCCTCTCCAGATCATCCTCCTCATCCTCTGTCCTGATATCACGCAAGACATGTCCAGAGATGCAGCAGAGGACGCCAAAGACAACAAGaagctgtttttggagaaTCTGCGGAAAGCTTTGACTGGCCACGGTGGAAGCAAACAGCTGACAGAGAGCGCAGCCATCGCCTGCGTTAAACTGTGTAAAGCGTCCACATACATCAGCTGGGAGGATCACTCTGTTATCTTCCTGCTGGTGCAGTCTATTGTCATGGACCTGAAGGGTTTGCTGTTTAACCCAGTTAAGCCGTTTTCCAGAGGCGCAGGAAGTCAGAGTGCAGACCTGGACTTAATGATCGACTGCTTCGTCTCCTGTTTCAGAATCAACCCACACAACAATCAGCAGTTTAAAGTGTGTTTGGCCTCGTCCTCCCCTTCAACCTTTCATTTCGTGCTGGTGAATTCTCTCCACCGCATCATCACTAATTCTCCACTGGACTGGTGGCCGAAGATCGACACAGTGTACTGTTATTCTGGAGAGCTACGGCTCATGTTTGCGGAGACTCTGGGACGAGTGGTGCAGGGCTGCAGTCACACAACGCTTCGATTGACTCCGAGTTTGACGTTTAAGGAGAAAATGAGCAGTCTGAAGTTTAAAGAGAAAACCACTGATCTGGACACCAGGAGTCTGAAGTATCTGCTCTTGGCTCTGGTGAAACTCATACATGCGGATCCCAAACTGATGCTCCATAATCCAGGAAAACAAGGTCTGGAGGTTCACAGCAGCACAGCAGAGCTCATCACAGGCCTCGTCCAGCTCGTGCCTCTTGCTAACATGGGAGAGATTTCCCAGGAGGCCATGGAGGCTCTGCTGGTCCTGCATCAGCCTGAAAGCATTGAGCTGTGGAACCCGGATGCCCCTATGGAGACCTTCTGGGACATCAGTTCTCAGGTGCTTTACTTCATCTGTAAGAATCTGTTTGGTCATCCGCTGGTTAGCAGTACTGAGATTCTGAAATGGCTGAGAGAGATTCTCATCTGCAGAAACAAGTTTCTTCTAAGGAATAAGGATCGGGCCACAGTGGGCAGCAACATTGCTACCTGCCGGCAGGCTCAGACCAAGCTGGAGGTCTGTCTCTACATGTTCCTGTGGAGTCCAGACATGGAGGCCGTTCTAGTGGCCATGTCCTGTTTCCGTTACCTGTGTGAGGAGGCAGAAATCCGGTGCGGTGTTGAAGACATCCCAGTGCAGTCTCTTCTGCCAAACTACAACACCTTCATGGAGTTTGCCTCTGTCAGTAACATGATGGTCACAGGTCGTTCAGCTCTACAGAAGAGAGTAATGGCTTTGCTTCGGAAGATTGAACTTCCCACTCCTGGAAACACAGAGGCCTGGGAAGACACGCATGCCAAATGGGAACATGCAACCAAGTTGATTTTAAGTCACCCGAAAACGAAACTGGAAGACGGTCAGGAATGGATCAATATGACAGGCTTCTTGTGTGCGTTGGGCGGTGTGTGTTTGCAGCAGAGGCATGTGTCAGCTCTGGCCACCTACAGTCCTCCTATGGGCACCCTGAATGACCGCAAGGGCTCGATGGTGTCGATGAGCTCTTGTGAGGGCAGCCCAGAGACACCTCTCGGCCGCTTTCTGGACCGTCTTCTGTCCCTGATGGTGTGCAGTCACGAAAAAGGCCATCAGATCCGCACTAATGTCAAAGACCTGGTGGGGCTGGAGCTCAGTCCAGTGCTTTACCCAATGCTCTTCAACAAACTCAAGAACAGCATCAGCAGATTCTTTGATGCCCAGGGGCCGGTGCCAATTAATGAGACCAACACACAGTTTGTGGAGCAGACCATCGCCATCATGAAGAACCTTCTGGACAACCATACAGAAGGTAGCTCGGAGCATCTGGGTCAAGCCAGCATTGAGACCATGATGCTCAACCTGGTCAGGTATGTGCGTATTCTTGGCAACATGGTTCATGCCATTCAGATTAAAACCAAATTGTGTCAGCTGGTGGAGGTCATGATGGAGCGCAGAGATGATCTTTCCTTCTGCCAGGAGATGAAGTTCAGgaaTAAGATGGTCGAGTATCTGACAGACTGGGTGATGGGAACCTCCAACCAGGCTGCTGATGATGATGTCAAATGCCTCACCAGGGATCTGGATCAGGCGAGTATGGAAGCGGTGGTGTCTCTTCTGGCCGGTTTGCCTCTTCAGCCAGAGGAAGGTGACGGAGTGGAGCTGATGGAGGCCAAATCTCAGCTCTTCCTGAAATACTTCACTCTGTTCATGAACCTGCTGAACGACTGCAGCGAGGTGGAGGACGAGGGTCAGCCGGTGGTCGGGAGGAAGCGAGGCATGTCCAGGCGATTGGCATCATTACGACACTGCACCATCCTGGCCATGTCCAACCTGCTTAGTGCCAATGTGGACAGCGGCCTGATGCACTCTATCGGCCTGGGCTATCATAAAGACCTTCAGACCAGAGCCACCTTTATGGAGGTGCTCACCAAGATTCTTCAGCAAGGCACAGAGTTCGACACGCTGGCAGAGACGGCTCTGGCGGACCGCTTCGAGAGGCTGGTGGAGCTCGTCACCATGATGGGGGATCAGGGCGAGTTGCCCATCGCAATGGCTCTGGCCAGTGTGGTGCCCTGTTCACAGTGGgATGAACTGGCACGTGTTCTGGTAACTCTCTTCGACTCGAGGCATCTGTTATATCAGCTCCTGTGGAATATGTTCTCTAAAGAGGTGGAGTTGGCGGATTCCATGCAAACGTTGTTCCGTGGCAACAGCCTGGCCAGTAAAATCATGACGTTCTGCTTTAAGGTGTATGGAGCCACATATCTGCAAAAGCTGCTGGAGCCGCTGTTGAGAAGTGTGATTGCGGGCACCGAGTGGCACATGCTGAGCTTTGAGGTGGATCCTACCAGACTTGAAAATGGTGAAAATTTGGAGGAGAACCAGCGGAATCTGCTTCGAATGACTGAACGCTTTTTTAAGGCCATAATCAGTTCATCTGGAGAGTTTCCTCCTCAGCTGCGCAGCGTCTGTCACTGTCTCTTTCAGGCTACATGTCACTCTCTCCTGTCTAAAGCCTCTGTCAAAGACAGAAAGGAAGTGAGGAAAGCAGTCGTGAGCCAGCGTTTTCCTCAGAACAGCATTGGAGCTGTAGGCAGTGCCATGTTCTTGCGATTCGTGAATCCAGCTATAGTCTCTCCATACGAGGCTGGGATTCTTGACAAAAAACCTCAGCCTAGGATAGAAAGAGGCCTAAAACTCATGTCCAAGATTCTCCAAAGTATTGCCAACCATGTTTTGTTCACAAAAGAGGAGCACATGAGGCCTTTCAATGACTTTGTGAAGAGTAATTTTGATGCTGCCAGAAGATTTTTCCTGGACATCGCCTCTGATTGCCCTGCTAGCGACTCTCTCAACCATAGCCTGTCCTTTATTAGTGATGGGAACGTTCTGGCTCTGCACAGACTGCTGTGGAACAATCAAGAAAAAATTGGCCAGTATTTATCTAGCAACAGGGATCATAAAGCAGTCGGAAGAAGGCCTTTTGATAAGATGGCCACCCTGCTCGCTTACCTGGGTCCCCCAGAACACAAACCTGTGGCAGATACTCACTGGTCCAGTTTGAATCTTACCAGCTCCAAATTTGAGGAGTTCATGACAAGGCACCAGGTCCATGAGAAAGAAGAGTTCAAAGCATTGAAGACTCTACACATCTTCTACCAGGCTGGAACATCAAAGAACGGAAACCCTGTGTTTTACTATGTGACGCGCAGGTTCAAGACGGGCCAGATAAATGGGGACTTGCTTATATACCATGTCCTTCTCACCCTCAAACCATACTATGCCAAACCCTATGAGCTAGTGGTGGATTTAACCCACGCTGGTCCAAGCAACCGCTTCAAGACCGACTTCCTCTCCAAGTGGTTTGTCGTCTTTCCGGGATTTGCATATGAAAACGTTGCTGCCATTTACATCTATAACTGTAACACATGGGTCCGGGAATATACCAAATATCATGAGAGACTCTTGACGGGACTCAAAGGCAGTAAGAAGTTACTGTTCATTGATTCGCCTGCACGGTTGGCTGAACATGTGGAACCAGAGCAACAGAAGCTTCCGGCAGCTACACTTGCACTGGAAGAAGACCTGAAAGTCTTTCACAATGCGCTAAAACTGGCCCACAGAGACACCAAAGTATCTATTAAGGTGGGCAGCACAGCAGTGCAGGTCACCTCAGCCGAACGAACACGAGTTTTGGGTCAATCGGTCTTCCTCAACGACATCTACTATGCTTCAGAGATCGAGGAGATTTGCCTAGTGGACGAAAATCAATTCACACTGACTATCGCTAACCAAGGGACGCCGCTGACCTTCATGCACCAGGAGTGTGAGAGCATAGTTCACTCCATTATCCACATCCGCACGCGCTGGGAGCTTTCCCAACCTGACTCCATTCCTCAACACACCAAAATCAGGCCCAAAGATGTTCCTGGGACCCTTCTCAACATCGCTCTCCTAAACCTGGGCAGCTCGGACCCCAGTTTAAGGTCTGCAGCTTATAACCTCCTGTGCGCCTTAACATGCACCTTTAACCTGAAGATCGAAGGGCAGCTTCTGGAGACGTCTGGCCTGTGCATCCCTGCCAATAACACTCTATTCATCGTGTCCATTAGCCAGACTCTAGCGGCTAATGAGCCTCACCTGACCCTGGAGTTCCTGGAGGAGTGTATCTCTGGATTCAGCAAGTCCAGTATAGAACTAAAGCACCTGTGTTTAGAGTACATGACTCCTTGGCTGCTGAACCTGGTACGCTTCTGCAAGCATAGCGATGATGCCAAAAGGCAACGAGTCACCGCCATTCTGGACAAACTCATTACCATGACCATCAACGAAAAGCAGATGTATCCATCCATTCAGGCCAAGATCTGGGGGAGCTTGGGCCAGATAACTGATCTCCTTGATGTAGTTCTGGACAGTTTCATTAAAACCAGTGCGACAGGAGGTCTCGGATCCATCAAAGCTGAAGTGATGGCGGACACTGCAGTGGCTTTGGCTTCTGGGAATGTCAAATTGGTGTCAAGCAAGGTGATCATTCGCATGTGCAAAATCATCGATAAGACGTGTCTGTCGCCCACACCAACACTGGAGCAGCACCTGATGTGGGATGATATCGCCATCCTGGCCCGGTACATGCTCATGCTGTCCTTCAACAACTCTCTGGATGTAGCCGCACACCTGCCGTACCTGTTTCATGTGGTGACCCTGCTGGTGGCCACGGGGCCTCTGTCTCTGCGGGCCTCCACGCATGGCTTGGTCATCAACATCATCCACTCCCTCTGCACATGCTCCCAGCTGAGCTTCAGCGAGGAGACCAAGCAGGTGTTGCGTCTCAGTCTGACCGAGTTCTCCCTGCCGAAGTTCTACCTGCTGTTCGGCATCAGCAAGGTCAAGTCGGCTGCGGTCATTGCATTTCGTTCCAGCTACAGGGATCGCTCATTCTCGCCGGGGTCCTATGAGAGAGAGACCTTTGCTCTGTCATCTCTGGAGACGGTCACAGAGGCGCTGCTGGAGATCATGGAGGCTTGCATGAGGGACAttccaggctgtaaatggctagACCAGTGGACCGATCTGGCGCAGAAGTTTGCATTTCAATATAATCCATCCCTCCAACCACGGGCACTTGTGGTATTCGGCTGCATCAGCAAACGAGTCACACATACGCAGATGAAACAGATCATACGGATCTTGAGCAAGGCCAGCCTTCTCCTCAGCATCGACCGGGGTTTGGAGAGCTGCCTGAAGGGTCCCGATAACTGTAACAGCCAGGTGCTAATCGAAGCCACAGTCATTGCTCTCACTAAACTACAACCTTTGCTCAACAAGGACTCAGCGATGCACAAAGCTCTGTTCTGGGTCGCTGTGGCCGTACTGCAGTTGGATGAGGTGAATCTGTATTCTGCAGGAACTGCTCTGCTTGAACAGAACCTACACACACTCGATAGCCTGAGAGTCTTCAACGACAAGAGTCCTGAGGAGGTGTTTATGGAGATCCGTCAGCCTCTGGAATGGCACTGTAAACAAATGGACCACTTTGTTGGCCTCAATTTTAACTCCAACTTCAATTTTGCTTTGGTCGGTCACCTGTTGAAAGGGTTCAGACACCCCTCCCCCACCACAGTGGCACGTACCATCCGCATCCTGCACATGCTGTTGGCGTTAGTAGGAAAACACCAGAACTGTGATAAATTTGAGGTGAACACACAGAGTGTGGCGTATCTGGCAGCGCTTCTCCCGGTGTCAGAGGAAGTGCGCAGCCGCTGCAGTCTGAAACACAGAAAATTGTTGCTTTTCTCTGATGTCACAATGGAGAATGTTCAAATGGATCCGTATTCTGTACATCACGAGGATCCAAGCGGCAGAACGTTGCGGGAAAACGAGCTGTGGGCATCCCCGAAAGTCTCAGAGCGATACTTGGTGGCCCATTTCCCCATAATGGGGCAGATCAGCCCACGAACACGCAAATCAATGAGCTTGGACATGGGACAACCCTCTCAAGTCAACACCAAGAAGCTTCTGGGCACCAGAAAAAGCTTTGACCTCCTGTTATCAGACAGCAAAGCACCAAAGAGGCCTGAAATAGAGACTGGTATCACAACGCCACCCAAGATGAGGAGAGTGGCTGAAAACGAATATGAAATCGAAACCCCAAGAATCTCCCATCACCACTTGCGGAAGGTTTCTGTGTCCGAGTCCAATGTCCTGCTTAATGAAGAAGTTCTCACAGATCCCAAAATCCAAGCACTGCTTCTGACTGTGCTGGCCACTCAGGTGAAAAACACTTCAGATGAATTTGAGCAGAGGATCTTGTATGAGTTTCTAGCCGAGGCCAGTGTTGTCTTCCCAAAAGTCTTTCCTGTTGTtCATAATCTTCTGGACTCTAAGATTAATACGTTGTTGTCGCTGTGTCAGGACCCACATCTTCTGAATCCAGTTCATGGAATTGTTCAGAGTGTAGTTTATCATGAAGAGTCTCCACCTCAGTACCAACCGTCCTACCTGCAAACTTTTGGGTTTAATGGACTCTGGAGGTTTGCCGGTCCTTTTTCGAAGCAAACTCAGTTCCCAGACTATGCAGAGCTGATAGTCAAGTTTCTGGATGCACTGATTGACACCTATCTTCCGGGCATTGATGAGGAAACAAGCGAGGAGGGTCTGCGGACACCCACCTCTCCATACCCTCCACCTGTGCAGAGCCAGCTCAGCATCACTGCCAACCTCAACCTCTCAAATTCAATGACCTCGCTGGCCACCTCCCAACATGCACCAGGAATGGATAAAGAGAAAGTGGATCTATCCCCCACCACGGGTTTGGCAGCCGGCGGACGCACACGCCACGGCTCGGCCAGCCAGGTCCAGAAACAGCGCAGCACCGGCAGCTTTAAGAGACCTAGCATTAAAAAGATTGTATGAGAACTGCAGCACAGCAGGGTTTCGCCTCTGCTGGACCTCTAACATACATTCTGCTGCCTTTTCTGCGGCTTCTCTTCACTCCCGCTAAACCCAGCATTTACGATAATCTTTAGGTTCTGCTGTTCGGGATCCAAATGAAAACCTCTGTTTTTAAAACCAGCCACTGTTTAACACGGATGGGAGGACGTCCAGTATTTTtagttatatttgtgcataatagAACTGAATagtatattgttttttaaaagcactaCATTCTTTCTTACTTTTAATACGTGGAAGTATTAACCAAGTGCCATTCCTTTGTTGCATTTATTTGGTTTGATTTATGAGACGCTTAAAAGAAATGTACAATCGTTCATGAACAACTACAAAAACGT

Function

symbol description
nf1b Acts upstream of or within several processes, including circulatory system development; learning or memory; and negative regulation of ERK1 and ERK2 cascade. Is expressed in blood vasculature; dorsal aorta; head; heart; and spinal cord. Human ortholog(s) of this gene implicated in autistic disorder; hematologic cancer (multiple); nervous system cancer (multiple); neurofibromatosis 1; and neurofibromatosis-Noonan syndrome. Orthologous to human NF1 (neurofibromin 1).

GO:

id name namespace
GO:0007507 heart development biological_process
GO:0043087 regulation of GTPase activity biological_process
GO:0007613 memory biological_process
GO:0001568 blood vessel development biological_process
GO:0046959 habituation biological_process
GO:0070373 negative regulation of ERK1 and ERK2 cascade biological_process
GO:0060251 regulation of glial cell proliferation biological_process
GO:0070444 oligodendrocyte progenitor proliferation biological_process
GO:0045685 regulation of glial cell differentiation biological_process
GO:0007165 signal transduction biological_process

KEGG: NA

ZFIN:

id description
ZDB-GENE-091111-4 Acts upstream of or within several processes, including circulatory system development; learning or memory; and negative regulation of ERK1 and ERK2 cascade. Is expressed in blood vasculature; dorsal aorta; head; heart; and spinal cord. Human ortholog(s) of this gene implicated in autistic disorder; hematologic cancer (multiple); nervous system cancer (multiple); neurofibromatosis 1; and neurofibromatosis-Noonan syndrome. Orthologous to human NF1 (neurofibromin 1).

Ensembl:

ensembl_id ENSDARG00000004184

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004425 True 8675 mRNA 0.50 57 37268854 37394957

Neighbor

gene id symbol gene type direction distance location
XLOC_002322 ksr1a coding upstream 11865 37173029 ~ 37256989 (+)
XLOC_002320 cuedc1a coding upstream 101403 37137464 ~ 37167451 (+)
XLOC_002321 CT027794.1 coding upstream 121070 37147669 ~ 37147784 (+)
XLOC_002319 vezf1a coding upstream 142292 37083654 ~ 37126562 (+)
XLOC_002317 NA coding upstream 204464 36805036 ~ 37064390 (+)
XLOC_002324 akap1a coding downstream 5881 37400838 ~ 37415223 (+)
XLOC_002325 NA coding downstream 83288 37478245 ~ 37478556 (+)
XLOC_002326 msi2a coding downstream 105277 37500234 ~ 37784024 (+)
XLOC_002327 NA coding downstream 470462 37865419 ~ 37889561 (+)
XLOC_002328 bhlha9 coding downstream 532143 37927100 ~ 37928125 (+)
XLOC_002318 BX323076.3 non-coding upstream 308164 36960576 ~ 36960690 (+)
XLOC_002315 CU694807.1 non-coding upstream 535843 36726238 ~ 36733011 (+)
XLOC_002299 BX088524.1 non-coding upstream 980351 36287841 ~ 36288503 (+)
XLOC_002330 NA non-coding downstream 630088 38025045 ~ 38034835 (+)
XLOC_002332 NA non-coding downstream 1037381 38432338 ~ 38433209 (+)
XLOC_002333 BX000451.1 non-coding downstream 1093751 38488708 ~ 38488829 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000304_17980209_18006985 NF1B, NF1 coding CI01000304 null 17979485 ~ 18007006 (+)
bowfin (Amia calva) AMCG00005552 LOC106567758,LOC106603288 coding CM030142.1 CM030142.1 3652635 ~ 3692107 (-)