XLOC_028364 (tbk1)


Basic Information

Item Value
gene id XLOC_028364
gene name tbk1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 134412 ~ 149334 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00055095
ATGTGATGAAAACACGGAAAACGGAAGAGACTGTCGTACTCTCGGGGTGGATCTACAGTCATCATGCAGAGTACGGCCAATTACCTGTGGATGATGTCCGACCTGCTGGGTCAGGGAGCCACAGCTAACGTGTACCGCGGTCGACACAAGAAAACAGGCGATCTGTACGCCGTCAAAGTGTTCAACAACCTGAGTTTCCTGCGGCCGCTGGACGTGCAGATGAGGGAGTTTGAGGTGCTGAAGAAACTCAATCACAAGAACATCGTCAAGCTGTTCGCCGTCGAGGAGGAGTCGAACACACGTCATAAGGTGCTGGTGATGGAGTACTGCCCCTGCGGGAGTCTCTACACCGTCCTGGAGGAGCCCACCAATGCGTACGGCCTGCCGGAGGACGAGTTCCTCATCGTTCTGCAGGACGTCGTGGCGGGAATGAATCACCTGCGCGAGTACGGCATCGTGCATCGAGACATCAAGCCAGGGAACATCATGCGAGTGATTGGAGACGACGGATTCTCTGTGTACAAACTCACCGACTTCGGAGCCGCTCGCGAACTGGAGGACGACGAGCAGTTCGTATCGCTGTACGGCACAGAGGAGTATCTGCATCCAGACATGTACGAGCGGGCGGTGCTGAGGAAAGACCACCAGAAGAAATACGGCGCTACGGTGGATCTGTGGAGCATCGGAGTCACGTTTTACCACGCCGCCACCGGCAGCCTGCCGTTCAGACCCTTCGAAGGGCCGCGCAGAAACAAAGAAGTCATgtaTAAGATCATCACAGAGAAGCCCCCCGGCGCCATCTCCGGACACCAGAAGTTTGAAAATGGGAAGATCGAGTGGAGCTCCGAGATGCCCATCTCCTGCAGCCTGtccaaGGGTCTGCAGAGCCTCCTGACGCCGGTGCTGGCGAATATCCTGGAAGCGGATCAGGAGAAGTGCTGGGGGTTTGATCAGTTCTTCGCAGAGACCAGCGACATCTTACACCGCATCGTGGTCTACGTCTTCAGTCTGCAGCAGGCCACGCTGCACCACGTCTACATACACACTTACAACacAGCGAACCTCTTCCAGGAGCTGCTGTTCAGACGCACCAACATCACTCCGTCCCATCAGGAGCTGCTCTACGAGGGCCGACGGCTCGTCCTCGACCCCAACCGGCAAGCACAAACCTTTCCCAAGACCTCCAGAGACAATCCCATCATGCTCCTGTGCAGAGACCCCGTCAACACCGTCGGCCTGCTGTTTGAGGACCCCAGCCCACCCAAAGTACAGCCGCGCTACGACCTGGACCTGGACGCCAGCTACGCCAAGacgTTCGCAGGTGATGTGGGATACCTGTGGAAAACATCAGATTCTCTGCTTCTGTACCAGGAGCTGGTGAGGAAAGGAGTCCGAGGCCTGAATGAGCTGATCAGAGATGAGTACAGTGAGACGATGCACAAGAAGACGGAGGTGTTCCACCTGTGCAGCCACTGCAGCCAGACACTGGAGCGCAGCGAAcaactctgtgAGGCGCTGATGCAGGGAAATATCCTGTCAGCCGAGTATGACGAGATCCGAGACACCAGGAAGAAGGTGCTGCGGCTCTCAGGCTCTCTAGCCTCTATGGATCAGACTCTGCAGGACATCAACAGCATGTTCCTGCCCGGAGGAAGCCTGACCGACACCTGGACGCAGCAGGTGGGAACACACCCCGAGGACCGCaatGTGGAGAAGATCAAGGTCCTGCTGGACGCCATCGGGGCCATTTACCAGCAGTTCAAGAAGGACAAGGCGGAGCGGCGTCTACCCTATAATGAAGAGCAGATCCACAAGTTTGACAAgcaGAAGCTGGTCCTTCACGCCACTAAAGCGCGAGCTCTGTTCACAGACGAGTGTGCCATGAAGTATCGCCTCTTCATCTCCAAGAGTGAGGAGTGGATGAAGAAGTTTCATCACGTGCGGAAGCATCTCCTGTCTCTGACTGGTCAGTTCAGCAGCCTGGAGCAGGAAGTGACTCTCCTCATGCAGCGCCTGTATAAGctgCTGGAGCAGTTCCCACAGAAGGTGGTCCCGATGGCGTCTGGTGTCCTGAAGCCGCAGGCGTATCTGAGCCCCAGCACACTCGTGGAGATGACCCTTGGGATGAAGAAACTGAAGGAGGAGATGGAGGGAGTGGTGAAGGAGCTGGCGGAGAacaacctgttcctggagagATTCGGCTCACTGACGGTGGATGGAGGAATGAGGACAGTGGAGCGGATgtgacatatacacacacacacacacactttcacatacACAgagatgcacacatacacacacacacacacacacacagtctctgtCTGTCTCTTGTACATATGGACAGTCTGtatatactctctctctctctctgcttcagTTGCGTCAGGATCAGCACTGTTACTGTTTTAAGTTCTGCTCTTCTcctcatcagtgtgtgtgtgtgtgtgtgtgtgcatgtgtgtgtgtgtttcactgaagcgctctctctctctctctctctctctctcggtcaGTGTAAATCAGGACTCTTGATATTTATAGGGCTTCATGTTTCTTTGTGTAAATGAGGATTAAACAGCAGCAGCGCTGAGTTCTGCTCAAACCTTCATCTGCTCGTCTGCTTCAGtccagctccacacacacactccatcctCACAGCACACACACTCGCTATCATCTGttagagcgcacacacacacaacatacgcCACTTTAGGCTGGAGTTAGTAATGATGGTAATCAGAgttcgccacagtgcaatgaaccaccaactattccagcatgtgttccacagtacccttccagccacaagccagtactgggaaacacccaaacacactcattcacacacactcccgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgcgcgcacaaatgcagtttgtaaagtccgAGTTCTGATGATTCTGTTGTTTTCAGTCTATATTGCTGATAATGTGTAGTTAAACTTGTTTAGTTTATATTTTGTGGCAGTAAAAGAAACAGAACAgataact
>TCONS_00057305
tgtgtgtgtgtgtgtgtgtttctctccgCAGGTCTACCCTATAATGAAGAGCAGATCCACAAGTTTGACAAgcaGAAGCTGGTCCTTCACGCCACTAAAGCGCGAGCTCTGTTCACAGACGAGTGTGCCATGAAGTATCGCCTCTTCATCTCCAAGAGTGAGGAGTGGATGAAGAAGTTTCATCACGTGCGGAAGCATCTCCTGTCTCTGACTGGTCAGTTCAGCAGCCTGGAGCAGGAAGTGACTCTCCTCATGCAGCGCCTGTATAAGctgCTGGAGCAGTTCCCACAGAAGGTGGTCCCGATGGCGTCTGGTGTCCTGAAGCCGCAGGCGTATCTGAGCCCCAGCACACTCGTGGAGATGACCCTTGGGATGAAGAAACTGAAGGAGGAGATGGAGGGAGTGGTGAAGGAGCTGGCGGAGAacaacctgttcctggagagATTCGGCTCACTGACGGTGGATGGAGGAATGAGGACAGTGGAGCGGATgtgacatatacacacacacacacacactttcacatacACAgagatgcacacatacacacacacacacacacacacagtctctgtCTGTCTCTTGTACATATGGACAGTCTGtatatactctctctctctctctgcttcagTTGCGTCAGGATCAGCACTGTTACTGTTTTAAGTTCTGCTCTTCTcctcatcagtgtgtgtgtgtgtgtgtgtgtgcatgtgtgtgtgtgt

Function

symbol description
tbk1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in brain disease and frontotemporal dementia and/or amyotrophic lateral sclerosis-4. Orthologous to human TBK1 (TANK binding kinase 1).

GO:

id name namespace
GO:0018105 peptidyl-serine phosphorylation biological_process
GO:0006468 protein phosphorylation biological_process
GO:0016310 phosphorylation biological_process
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG:

id description
ko04014 Ras signaling pathway
ko04140 Autophagy - animal
ko04137 Mitophagy - animal
ko04620 Toll-like receptor signaling pathway
ko04621 NOD-like receptor signaling pathway
ko04622 RIG-I-like receptor signaling pathway
ko04623 Cytosolic DNA-sensing pathway
ko04657 IL-17 signaling pathway
ko05170 Human immunodeficiency virus 1 infection
ko05161 Hepatitis B
ko05160 Hepatitis C
ko05171 Coronavirus disease - COVID-19
ko05164 Influenza A
ko05162 Measles
ko05168 Herpes simplex virus 1 infection
ko05163 Human cytomegalovirus infection
ko05167 Kaposi sarcoma-associated herpesvirus infection
ko05169 Epstein-Barr virus infection
ko05165 Human papillomavirus infection
ko05131 Shigellosis
ko05135 Yersinia infection
ko05014 Amyotrophic lateral sclerosis
ko05022 Pathways of neurodegeneration - multiple diseases
ko05417 Lipid and atherosclerosis
ko01001 Protein kinases
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-060512-359 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in brain disease and frontotemporal dementia and/or amyotrophic lateral sclerosis-4. Orthologous to human TBK1 (TANK binding kinase 1).

Ensembl:

ensembl_id ENSDARG00000103095

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00055095 False 3025 mRNA 0.53 21 134412 149334
TCONS_00057305 True 722 lncRNA 0.51 6 134963 137757

Neighbor

gene id symbol gene type direction distance location
XLOC_028363 gpr19 coding downstream 920 128697 ~ 133492 (-)
XLOC_028361 dusp16 coding downstream 14723 107287 ~ 119689 (-)
XLOC_028362 NA coding downstream 15218 116322 ~ 119194 (-)
XLOC_028360 NA coding downstream 33035 99991 ~ 101377 (-)
XLOC_028359 NA coding downstream 59804 73430 ~ 74608 (-)
XLOC_028365 eps8a coding upstream 2172 151506 ~ 178510 (-)
XLOC_028366 ptpro coding upstream 35529 184863 ~ 193762 (-)
XLOC_028367 ptpro coding upstream 41213 190547 ~ 211714 (-)
XLOC_028368 RERG coding upstream 84478 233812 ~ 240737 (-)
XLOC_028369 si:ch73-252i11.1 coding upstream 120109 269443 ~ 277081 (-)
XLOC_028358 NA non-coding downstream 61754 71463 ~ 72658 (-)
XLOC_028357 NA non-coding downstream 69709 56025 ~ 64703 (-)
XLOC_028373 NA non-coding upstream 244217 393551 ~ 396819 (-)
XLOC_028375 CU855889.2 non-coding upstream 552278 701612 ~ 734347 (-)
XLOC_028376 NA non-coding upstream 574496 723830 ~ 732484 (-)
XLOC_028383 NA non-coding upstream 750628 899962 ~ 904022 (-)
XLOC_028385 NA non-coding upstream 770418 919752 ~ 921761 (-)

Expression


Co-expression Network