XLOC_030142 (serpina7)


Basic Information

Item Value
gene id XLOC_030142
gene name serpina7
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 28830388 ~ 28832950 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00058940
ACAGGCTTTATAACTCGACTAGTCTAGTTTGAGAAAAGAGGAACAACAGCTGTCTGAAGAGAGACTTCAAGACCATGGAACAGAACGGTGTATTTTTGTGGATTTTTGGTTTTGCAATAGTTGTCTGTGGGAATCAAGAGACTTTACAACAACCTCCCATTAGCGCTAAACTCCCGTCATTGATAAACATGAACAACGATTTTGCTTTTCACCTGTACAAGAGGCTTATAGAATCGCCTGACTATCAGTCTAAAAACATCTTCTTCTCTCCGTTCAGTGTGTCTATGGCCCTTTCTGAGCTTTCTTTAGGAGCCGGTGGAGACACCAAACAGCAGCTTCTCAGTGGCATTGGCTACAACAGTGCAATCTTCAGCACTGAGGAAATGCACCAGCTGTTTCACAGTCTCCTGGAAGAAATCGGCAATAGGACAGAAGTGGACATTGATGTCGGTACTGCTCTTTATGCAAGCGACCGATTTAAGCCTCATtctaagtttctggaggacatgAAGGAGTTTTACCACTCGGATGGCTTCACTGTAGATTTTAGTGTCAAAGAAACAGTcgatcaaattaataaatatgtggAGGAAAAAACACATGGAAAAATCAGTCAAGCTGTCGATAATCTGGAAAAGGATACTTTGATGTTTCTTCtcacatacatatattttaaagGAAAATGGGACAAGCCTTTTAAGCCAGAAACAACCAGCGAGAGTACATTTTATATAGATGATAAGACCACCGTTCCAGTGCAAATGATGCACCAGTATGAACATCTCAAAGTCTATTATGATGTTGAACTATTCACTAAAGTCCTCTGTCTTGACTACAACGATTCCTTCTCCATGATTCTGGCTGTCCCAGATGTTTACATGAAGCAAAAAACCATGAAAGATCTAGAGATGACAGTCTCTAGACAGCACATTGAAAAGTGGAGGAGAAGTGTATCTGAACGAAAAGTTGACATCTACGTCCCCAAGCTTTCTCTGAAAACATCATACTCCCTGAAGGATATTTTGAAGGGAATGGGAATGACTGATATGTTTTCAGATAAAGCCGACTTTACAGGAGTTTCAGAGGAAAATATCTTCGTTTCAAAAGTTTTGCATAAAGCCACTCTGGATATCGATGAGCAAGGAACCACCGCAGCAGCAGTGACAGGAGTTGAAATAAGACCAACTTCCTACGACCCACTGAGTGATTTGAAATTTGATCACCCATTCATGATCTTTATCACGGATCAAACAAATGACAACATCCTTTTCGTTGGGAAAGTCGTCAACCCAAATGAAAAACTGTGATGTGGCCCACAAGATGTTAAAACAAAGTTAGCCAGTAGGTGGAAACCATTTAACAACTGCAGTGCCATATATTGCAGACTACTAGAGTcgccttcctgcagagttcagttcTTATTGTTAGAAAACAGCTGGATCAGCTAATGTAGGTGATGGTTGGAAATAAACTGCAAGAAAATAAACCTGCAACACAGG
>TCONS_00058941
GAGACTTCAAGACCATGGAACAGAACGGTGTATTTTTGTGGATTTTTGGTTTTGCAATAGTTGTCTGTGGGAATCAAGAGACTTTACAACAACCTCCCATTAGCGCTAAACTCCCGTCATTGATAAACATGAACAACGATTTTGCTTTTCACCTGTACAAGAGGCTTATAGAATCGCCTGACTATCAGTCTAAAAACATCTTCTTCTCTCCGTTCAGTGTGTCTATGGCCCTTTCTGAGCTTTCTTTAGGAGCCGGTGGAGACACCAAACAGCAGCTTCTCAGTGGCATTGGCTACAACAGTGCAATCTTCAGCACTGAGGAAATGCACCAGCTGTTTCACAGTCTCCTGGAAGAAATCGGCAATAGGACAGAAGTGGACATTGATGTCGGTACTGCTCTTTATGCAAGCGACCGATTTAAGCCTCATtctaagtttctggaggacatgAAGGAGTTTTACCACTCGGATGGCTTCACTGTAGATTTTAGTGTCAAAGAAACAGTcgatcaaattaataaatatgtggAGGAAAAAACACATGGAAAAATCAGTCAAGCTGTCGATAATCTGGAAAAGGATACTTTGATGTTTCTTCtcacatacatatattttaaagGAAAATGGGACAAGCCTTTTAAGCCAGAAACAACCAGCGAGAGTACATTTTATATAGATGATAAGACCACCGTTCCAGTGCAAATGATGCACCAGTATGAACATCTCAAAGTCTATTATGATGTTGAACTATTCACTAAAGTCCTCTGTCTTGACTACAACGATTCCTTCTCCATGATTCTGGCTGTCCCAGATGTTTACATGAAGCAAAAAACCATGAAAGATCTAGAGATGACAGTCTCTAGACAGCACATTGAAAAGTGGAGGAGAAGTGTATCTGAACGAAAAGTTGACATCTACGTCCCCAAGCTTTCTCTGAAAACATCATACTCCCTGAAGGATATTTTGAAGGGAATGGGAATGACTGATATGTTTTCAGATAAAGCCGACTTTACAGGAGTTTCAGAGGAAAATATCTTCGTTTCAAAAGTTTTGCATAAAGCCACTCTGGATATCGATGAGCAAGGAACCACCGCAGCAGCAGTGACAGGAGTTGAAATAAGACCAACTTCCTACGACCCACTGAGTGATTTGAAATTTGATCACCCATTCATGATCTTTATCACGGATCAAACAAATGACAACATCCTTTTCGTTGGGAAAGTCGTCAACCCAAATGAAAAACTGTGATGTGGCCCACAAGATGTTAAAACAAAGTTAGCCAGTAGGTGGAAACCATTTAACAACTGCAGTGCCATATATTGCAGACTACTAGAGTcgccttcctgcagagttcagttcTTATTGTTAGAAAACAGCTGGATCAGCTAATGTAGGTGATGGTTGGAAATAAACTGCAAGAAAATAAACCTGCAACACAGGGT

Function

symbol description
serpina7 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be active in extracellular space. Is expressed in blood and liver. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to several human genes including SERPINA1 (serpin family A member 1); SERPINA12 (serpin family A member 12); and SERPINA7 (serpin family A member 7).

GO:

id name namespace
GO:0010951 negative regulation of endopeptidase activity biological_process
GO:0005615 extracellular space cellular_component
GO:0004867 serine-type endopeptidase inhibitor activity molecular_function

KEGG:

id description
ko04918 Thyroid hormone synthesis
ko01002 Peptidases and inhibitors

ZFIN:

id description
ZDB-GENE-041010-47 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be active in extracellular space. Is expressed in blood and liver. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to several human genes including SERPINA1 (serpin family A member 1); SERPINA12 (serpin family A member 12); and SERPINA7 (serpin family A member 7).

Ensembl:

ensembl_id ENSDARG00000087143

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00058940 False 1499 mRNA 0.41 5 28830388 28832948
TCONS_00058941 True 1441 mRNA 0.41 4 28830643 28832950

Neighbor

gene id symbol gene type direction distance location
XLOC_030141 CR559930.1 coding upstream 4248 28824612 ~ 28826140 (+)
XLOC_030140 zgc:174260 coding upstream 11775 28812453 ~ 28818613 (+)
XLOC_030139 si:ch211-186e20.7 coding upstream 28138 28797771 ~ 28802250 (+)
XLOC_030138 trafd1 coding upstream 40288 28770273 ~ 28790100 (+)
XLOC_030137 NA coding upstream 268251 28561003 ~ 28562137 (+)
XLOC_030143 zgc:174259 coding downstream 15920 28848870 ~ 28851407 (+)
XLOC_030144 si:ch211-186e20.2 coding downstream 25019 28857969 ~ 28859840 (+)
XLOC_030145 NA coding downstream 83569 28916519 ~ 28918961 (+)
XLOC_030146 stxbp1b coding downstream 139985 28972935 ~ 29002322 (+)
XLOC_030147 dpp7 coding downstream 326827 29159777 ~ 29177272 (+)
XLOC_030136 NA non-coding upstream 327211 28497934 ~ 28503177 (+)
XLOC_030135 NA non-coding upstream 338870 28393348 ~ 28491518 (+)
XLOC_030148 CT956057.3 non-coding downstream 381580 29214530 ~ 29214646 (+)
XLOC_030149 NA non-coding downstream 408844 29241794 ~ 29243160 (+)
XLOC_030150 NA non-coding downstream 727109 29560059 ~ 29565825 (+)
XLOC_030153 NA non-coding downstream 951222 29784172 ~ 29792624 (+)

Expression


Co-expression Network