XLOC_030822 (nipbla)


Basic Information

Item Value
gene id XLOC_030822
gene name nipbla
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 8005911 ~ 8096232 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00059965
GCTTTTGTTGGCAAACAAAGGCGCAACGCTAAAGTGTTTCCCGAGCATCCAGGCGACGAGCTAAGACGCGGCCGAATTAAAAGTGTGCTCCATCCCgttacatgtttttaaaagtgcgaTGAGAGAAAGCCTGACCTCCCCCACCCCAGATAAAGATAGAGTTGGCTTGTTGTTAGCTGGCTCGGCTAAACAAACCCCGCTAGCCCGCGCTGATCTTTTTATAGCAGAGAGGGGGAGCCAGAGACTTACAGCAGACCGACTACCAGCCTCTCATCCCAACAACAGTCcccttattttttcttctttgaaGTTACCCCAAGCTAAGGATTGAGTGAGATGTGAGGGATGGTCAGCGAATAAATATCTCTGTGGATCTCTGTGTGCGTTAGACTTCTGTGCCCAGCCGTCAGTATGAATGGGGACATGCCACATGTGCCCATTACAACCCTTGCTGGGATCGCTGGTCTCACTGACTtgtTGAACCAGCTGCCCCTGCCCTCCCCTTTACCGGGCACCACCACTAAGAGCCTGCTGTACAATGGGCGAGTAGCTGAGGACGTGGGGCATCTGTTGGGCTGCAGGGATGAAACTCTGGTCTCTCAGCTCGCCAACAGCCTCAGCCAGGTCTCCACGGAGCACATAGAGCTGAAGGACAGCCTGGGCAGTGATGAGCTTGAGGGAGATGTACCAGTGCTGCTGCAGCTTTTGATGTCCAGAAACCCTAACATCTTCAGGAATAAGACTGCACCAAACACTCCACAGTATCCGGCCCAAGCGGGTATAAGTCAGCAGTCAATGGCACCGCCGTATAAAATCACACATGGCTCCATGCAGGGAAGCCCAGCCTCTGCCAATTATCAGCAGGCCTCCATGTCCCACAGTCCCTCTGGGCATTTTGTACCGGGCCAGTCTGGTCCTGGTGGACGGTTTCTTCCTCAGCAGGGCAGTCCAGTGCCCAGCCCATATGCCCCCCAGAGCCCTGCTACTGGTTACAGACAGTACCCTCACCCTCCAGCCTATAGTCAACACCAGCACCTACAGCAAgGTTCAGTAGCAAGTCCCATGATCCCAGGAGCCATGagaaatgtgcatgaaaataagGATCAAATGAGGATGGGTTTCACGTCTCACTTACTGCAGTCATCTCCACCGTACACCCCTCCCTGCGACGGGACTAAAGACCTGCACCTGGGCTCCCAGGACAAACAACGAGGTCAGAAGTCCAGCGAGGGAGAGCAGGACTCCCCTGATAAGGCCACCGTGTACGATATTGTGGGCTCGCCAGCGAAAGACCACACTAAGCTGATCCTGAGGCCGTCACGGGCGAGGCCAGCCGAGGTGGAGCTTGGGGGAATGTACCCAGGCTCAGACCCAGAAGGAGAGCTCGTGGAGGCTCTTGCTGCTATAGAGAGGATGGAGAGTGAAGCAGCGATGGAGACTGAACGCAGTGCTAAAGAGGTGCAGGACAAAGATAAGCCTTTGAAGAAGCGCAAGCAGGACTCTCACCCCCAGGAGCCTGGCGCAGCTGGCACAGCAGGTTCGGGCTCTGGGGCTcaaggtggaggaggaggagctaatGCAGGCCACAGGCTGGCTCCTCAGGAGGCCAGTGCTGCAGGCACCAGCGCCAGCCGCCCGGGTCTGCAGGTGAGCTTGGAGCAAGCAGGCAGAGTGGAGGACGACTGCATGGGTATGCCCATCCCTGCAAGCGAGGCGCAGCGCTGGCCTCAGGAGCCACAGGAGGGCGTCACCCCAAAGGCCGTCAAACACGAGCACGACCATGATCCAGAACACCCGCATTATGATGACAAACAGCCCGATACCCCACGGCAAAAACATCGACCCGAGGGCCGGCATGGCGATGGAGGTGCACAGCGAGCGGCGGTTCAATCAGGAAGTAAACAGGTCGAGCTTCCTCCGTACATGCTGGGTGAAAACACGGGAGTGCTTAAGAATTTCACCATTCCCAAAATCAGGAAAGGGGAGCTCGGGGGCGGTGATATTCCTGAAGGATGGAAGCAGCCTTGCGTGCGGCTGGAGAGACTAGAAGCGGACGTGGACGTGAAGAAGAGCGTCAAGCCTGTGGTGGTTCTGCAGAAACTCTCCATCGATGAGGTGCAGAGGCTGATGAGGGAGAGAGACTCACGGGCCTCCAAGTCCGGCAAGAACAGGCTCTCCTCTGGGAGATCTGGGAAAGGTGGAATAGACCCGTCTGTGCTGAAGGATCTTCCTCCTGAACTGCTGGCAGAGATCGAGTCCACCATGCCTCTGTGTGAGCGGGTGAAGATGAACAAACGGAAACGCAGCACTGTTAATGAGAGGCCTAAATATGCAGAGGACAGCTCAGAGGATGAGGAGTTCTCTTCTCGTAAACGTCAGAGGAAGGACCGGGATCGAACATGGGAGGCTGAAGAGCGAGACCGGAGGAGTTCAGGAGAGCATCGAAGAGGAAACTTTGATGCACGAAGAGGCTCCGGCAGCCGATACGACGACTCGGACCAAGATTCACCTCCACCCAGCCTTAACGAAGTTGCAAGACGTTTAAAGATGAAGCAGAAGAAGAGGAAAGTGTATGAGCCCAAGCTGACTCCTGAAGAAatgatggactcttccacctttAAGAGGTTCACGTTAAGTATTGACAACATCTTGGAGAATCTCGAGGATGTGGACTTTACAGCTCAGGatgatgATGAGATCCCTCAGGAGCTGTTGTTGGGCAAGCAACAGCTAAATGAATTGGGCAGTGAATCTGCTAAGATAAAAGCCATGGGCATCACGAGCAGGATTCCTTCTGATAAACTCGTGAAACTGTTGAACATCCTGGAGAAGAACATTCTGGATGGAGCCAGTCTTTCCACACTCATGAACCTTGATAATGAGGGTGAGGATGAGGAGCGTCTCTGGCGTGATCTCATCATGGAGCGAGTGACCAAATCAGCAGACGCGTGTCTGACAGCACTGAACATCATGACATCGACACACATGCCCAAAGCCGTGTACATTGAGGACGTGATCGAGAGGGTTTTACAGTACACTAAGTTCCACTTGCAGAACACGCTTTATCCGCAGTATGATCCAGTCTACAGAGTCAACCCTAAAGGAGGTTCCATGCTCAGCTCCAGAGCGAAGCGAGCGAAGTGTTCCACTGCCAAGCAGAAGGTCATCATTATGCTCTATAACAAAGTGTGTGACGTGGTCAGCAACATCTCAGAGCTGCTGGAAATTCAGCTGATGACTGATACAACAATATTGCAGGTCTCTTCGATGGGCATCACTCCGTTCTTTGTGGAGAATGTCAGTGAGCTGCAGCTGTGTGCCATAAAGCTGGTGACGGCGGTCTTCTCTCGTTACGAGAAGCACAGGCAGTTAATCCTAGAGGAGATCTTTACCTCTTTGGCTAGATTGCCCACCAGCAAACGCAGCCTCAGGAACTTCAGgtTGAACAGCAGCGATGATGAGGGTGAACCCATATACATACAGATGGTTAGTGCTCTAGTGCTgcagttaatccagtgtgtggTCCATTTGCCGGCTGACAGAGACTCTGAGGATGATCACAAGAAGGTTGACGATGATGTGTTCATTACCAACTCGTATGAAACAGCCAGGCGGACTGCTCAGAACTTCCTCTCCGTCTTCCTCAAGAAGTGTGGCAGTAAACAGGGTGAGGAAGACTACAGGCCGCTGTTTGAGAACTTTGTGCAGGATCTGCTGTCAACTGTCAACAAACCCGACTGGCCCGCTTCAGAATTACTGCTGAGCCTTCTGGGAAGATTACTGGTGCATCAGTTCAGTAATAAGCAGACAGAGATGGCTCTGCGAGTGGCATCGCTGGATTATCTCGGTACCGTAGCAGCCAGATTGAGAAAAGATTCCGTCACCAGCAGGATGGACCAGAAAGCCATAGAACGCATCATCAGAGAGAACACCGAGGGAGATGAGACTCAGCGGTTACAGAAAGCTCTGCTGGATTATATGGATGAGAATGCAGAAACAGACCCTGCTCTTGCATTTGCACGTAAATTTTACATCGCTCAGTGGTTCCGAGACTGCACTACGGAGACCGAGAAGGCCATGAGGAGTCAGAATCAGAAGGAGGATGATTCAGACGGGGCACAGCACGCCAAAGAGCTCCAGGCCACAGGAGACATCATGCAGCGCGCTGAAACCCGCAAGAAATTCCTCCACTCCGTTGTTAAATCAACTCCTAATCAATTTACTACTCTCAGGATGAATTCAGACACTGTGGACTATGACGACGCCTGCCTTATTGTTCGCTACCTGGCCTCCACCAGACCCTTCTCTCAGAGCTTTGACATCTACCTGACACAGatTCTAAGAGTGTTAGGGGAGAGCGCCATAGCTGTCAGGACCAAAGCCATGAAGTGTCTGTCCGAGGTTGTGGCTGTTGACCCAAGTATACTGGCCAGGTCTGATATGCAGCGTGGTGTTCACGGGCGATTGATGGATAACTCCACAAGTGTGAGAGAAGCAGCGGTCGAGCTGCTGGGACGCTTTGTGTTGAGTCGACCTCAGCTGACGGAGCAGTACTACGACATGCTCATCGAGAGGATACTGGACACCGGTATCAGCGTAAGGAAGAGGGTGATCAAGATTCTGAGGGACATCTGTTTAGAGCAGCCCAACTTCAGCAAGATCACAGAGATGTGTGTAAAGATGATCCGCAGGGTCAATGACGAGGAAGGCATCAAGAAACTGGTGAATGAAACATTCCAGAAGCTGTGGTTTACTCCCACACCCAACCACGACAAAGAGACGATGAATAGGAAGATTCTCAACATCACTGATGTGGTCTCTGCCTGCAAGGACACTGGCTATGACTGGTTTGAGCAGCTCCTGCAGAACCTTTTAAAGTCAGAGGAGGATTCGTCCTATAAGCCAACCAGGAAGGCCTGCGTGCAGTTGGTTGACAATCTTGTGGAGCACATCCTCAAATATGAGGAGGCACTTGCAGagcaTAAAAGTGTGAACTCGACGCGGTTGGTGGCGTGCATCACCACGCTGTATCTGTTCAGTAAGATCAGAGCGCAGCTGATGGTCAAGCATGCTATGACTATGCAGCCCTACCTCACCACCAAGTGCAGTTCTCAGAGTGACTTCATGGTGATTTGTAATGTTGCAAAAATCCTAGAGCTGGTGGTTCCTCTGATGGATCATCCCAGCGAGAGCTTCCTGACCACCATTGAAGAAGACCTGATGAAGCTCATCCTAAAATATGGCATGACCGTTGTCCAGTACTGTGTGAGCTGTTTGGGTGCGATTGTGAATAAAGTCACCCATAACTATAAGTTTGTGTGGGCCTGTTTTAACCGTTATTATGGGGCTCTTACTAAGTTAAAGGTCCAGCATCAGGAGGGAACGAACAGCATGGCGTTGGCTGCTACCAAAGCGGCCCTGCTCAGATCTCTGTTCACCGCCGGCGCGCTCTGCAGACACTTCGACTTTGATCTGGAGCAGTTCAAGGGCACTACTAAGGTTGTAATAAAGGAGAAGGTTCTGGaattattactgtatttcaccaatCATGAGGACGAGGAAGTTAAATGCAAAGCCATCATCGGGTTGGGCTTCCTATTCATCATGCACCCGAGTCAGATGTTCGTTCCTGAGGTGAAGACCCTGTATAACGGGCTTCTCTCTGATAAACGGAGCTCCATCACACTGAAGATCCAGGTGTTGAAGAACCTTCAGATGTACCTTCAGGAAGAGGATACTCGCATGCAGGAAGCAGACAGAGAATGGCAGAAACTGTCGAAGCAGGAGGACCTGAAAGAGATGGGTGACATCTCCTCTGGTATGAGCAGCTCCATCATGCAGCTTTATTTGAAGCAGGTGCTGGAGTCGTTTTTCCATGCACAGTCCAGTGTACGACACTTTGCCCTCAATGTCATCGCTCTGACACTCAGCCAGGGACTCATACACCCTGTACAGTGTGTGCCATATCTGATCGCGATGGGCACAGACGCAGAGCCCACCATGAGGAACAAAGCAGACCAGCAGCTGGTGGAGATTGATAAGAAGTACACTGGATTCATCCATATGAAAGCTGTAGCAGGGATGAAGATGTCGTACCAGGTGCAGCAGGCCGTCTTTGGATCAGCCGGGTCTGTGATCCGAGGTTTCCGTCAGGATGAGTCTAATTCAGCTCAGTGTTCGCACCTCTACAGCATGGTCCGCGCAAACAGACAACACCGGCGAGCGTTTCTCATCTCGCTGCTCAATCTCTTCGACGACAGCTCGAAGATGGAGGTGAACATGCTGTTGTTCATCGCTGATAATCTGGCCTACTTCCCCTATCAGAGTCAGGAGGAGCCGCTGTTCATCATGCATCATATAGATATCACACTGTCTGTATCGGGGAGCAACCTGCTGCAGACCTTTAAAGAGTCTCTGGTTAAGATACCAGGCAGGAAAAGCAGGAAAAGGAGACGACGGCGGAGGCGACCGCAACGCCAgcaaccaccaccaccaccaccacaacaacaacagcagcagcagaacgGCTCAGAGGAGGAGAGAGGAGCACAAGATGAGGAGAGAGAAAGACATAGTGGAGATGAGGAGTATGACGATGATGATTATGAGGAGGATGAGGACGGCCATCGGGTGAGGAAGCCCAAGCCCACGGAGGACATCAGACAGTCGGAGTCGGACTCAGACTCGGACCTCGACGATGTTGATGCTGTAATGGAGCGTCTTCCTGATGACTCAACATCGCTTGTGGACTTTGCCAGAGCGTCGCAGGGCATACTGTTACTGCTGGTGCTCAAACAACACCTCAAGAACCTCTACGGCTTCTCTGACGGTAAAATTCAGAAGTACTCTCCCTCTGAGTCGGCCAAGGTGTACGATAAAGCCGTAAACAGGAAGACGTTGGCCAACTTCAACCCACAGCAGACCATCGACTTCCTCCGTCATCATGACGTTCATGGCGAGCTGACCTACGAGCTGAAGAGGAAGATCGTCAAACAGTTCCTCGACTTTAAGCTGTTGATGGAGCACCTGGACCCTGATGAGGAGGATGAAGATGGAGACACGAGTGCAAACGTGAGGAATAAAGCCATCACTGCACTGCTGGGTGGAGCGGCTGCAAGTCCCCGAAACCACCACACAGGCGACTCTGAGGAGGACGATGAGAGGAGTGAAGGAGAGGAGAGGACCCCCGGGGCATCTCGACGTGGGAGACGAACTGGAGACTCAGCAGACCTGCTGTCCGCGAACATGAATGAATCCGTCAGCGCGCTTGATATCATCGCCATCCACTGCCCCAAATACCGCGACCGGCCGCAGATCGCCCGCGTCATCCAGAAGAACAGCGACGGCTACAGCATCCACTGGATGGCCGGCTCATACTCCAGCACGTGGGCCGAGGCCAAAAAGCGTGACGGACGCAAGCTGGTGCCTTGGGTGGACAGCATCAAAGAGACCGACATCATCTACAAAAAAATCACGCTCACCAGTGgcaacaagctcaaccacaaagTGGCGCAGACTCTACGTTCACTCTACGCTGCCAAGGACAGGAACTCCAGCTAATAATACGTAAATAAACACACGCAGGCACGCACATACCTCCCATCTCAGATCCTTTCAGCCTAATGCAACACACTCAACGTCTCTCCATGAACAGCCAAACATCTACCAGgtcagccaaacacacacactcaaaaacacgAGCGGCTATTCTACACTAcagactctttctctctctctctctctctctctctctttctctctgatgCACTCTGGCTCTGGTGGTGACATTTTTTTTGTCCTCTGCACCAGGGTGCATCGTCGTATCGCAGGAATAAAAATGTTTGGAGAAACATTGTATGGGTGCTCCTTCGCTGTTGTGCAGCAGATTTCTGGTTGTTTGATTTCTACTCCCAGTGTATCATAGTTtaacataaaaatattgtttatatctataaaagaaatttaaatatatactgAATGTTGAAAGAATtagtttgttgatgtttttactttttattttctgatttttctttattttttttctcttgtttttttttttttcttcggaaTTCCTAGCGTCAAGCAGCTTTCTATATAGCTTAGCTCCTTCTTTACTGGCTGATGACGACTCTCTCTGTTTGTCCATTTTTGTACGATAGCACCGTGTGGCTGTAATTTATTGTGTATAGCATGCAGTGTCTGTGAGGAGGGCTGTGTCGAAGGAGATTTTTGCGATAACAGGTCGCCCTGCTCAGCGTAAAGGGACCCACATGCCTCTGATGGaacaaatactgcaataaattTTCTACTTCTCTTA
>TCONS_00061514
GCGCTGATCTTTTTATAGCAGAGAGGGGGAGCCAGAGACTTACAGCAGACCGACTACCAGCCTCTCATCCCAACAACAGTCcccttattttttcttctttgaaGTTACCCCAAGCTAAGGATTGAGTGAGATGTGAGGGATGGTCAGCGAATAAATATCTCTGTGGATCTCTGTGTGCGTTAGACTTCTGTGCCCAGCCGTCAGTATGAATGGGGACATGCCACATGTGCCCATTACAACCCTTGCTGGGATCGCTGGTCTCACTGACTGTAAGTACATGCATCAGATTACTCATGCTTCATTCGTCTGTCTGCAGTCTCCGCCCACTTTTTCAGCGGGattggtttaaaaacaatatccCATTCGTTTGTTTTCATTGCAGGAACCATGCAAAACATCGCAGTCCTTTGTTTTGAAGCGTAAAAACCACTGTTTAcattctttaatattttattgaacaatttataaacgatgcaaattgtgatttttatttatttgtttgtttgcttgcttgtttgttcgtttattcattcTTGTCTTTTTCCCTCAATTTTTTTGGATCAcattgtaataacaatgaaacaaaacaagTTTCAGTGTAAGTTAATGGAGTTTTTTTCTGTAAGTTGAGTTTTCAGGAACCCTTTTTGAAGgaatctttacatttttattcagttttattcctggtaaaatgattattattatttctaaaataactataatattagctataacaacaactacaataataataatatttgttttctgaaataatgtatttaatcaCACAGACATGCTCAACATCAGAGATTATTCTCATTTGGTCTTTCTGCAGTTTGATGATCTGGAATGAT

Function

symbol description
nipbla Enables chromatin loop anchoring activity. Acts upstream of or within digestive tract development and embryonic morphogenesis. Predicted to be located in nucleus. Predicted to be part of Scc2-Scc4 cohesin loading complex. Is expressed in Kupffer's vesicle; blastoderm; blastodisc; head; and lateral plate mesoderm. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 1. Orthologous to human NIPBL (NIPBL cohesin loading factor).

GO:

id name namespace
GO:0006302 double-strand break repair biological_process
GO:0007507 heart development biological_process
GO:0003146 heart jogging biological_process
GO:0070550 rDNA condensation biological_process
GO:1990414 replication-born double-strand break repair via sister chromatid exchange biological_process
GO:0007275 multicellular organism development biological_process
GO:0048565 digestive tract development biological_process
GO:0071921 cohesin loading biological_process
GO:0010468 regulation of gene expression biological_process
GO:0007049 cell cycle biological_process
GO:0071169 establishment of protein localization to chromatin biological_process
GO:0007064 mitotic sister chromatid cohesion biological_process
GO:0035118 embryonic pectoral fin morphogenesis biological_process
GO:0007076 mitotic chromosome condensation biological_process
GO:1905406 positive regulation of mitotic cohesin loading biological_process
GO:0034087 establishment of mitotic sister chromatid cohesion biological_process
GO:0003007 heart morphogenesis biological_process
GO:0071733 transcriptional activation by promoter-enhancer looping biological_process
GO:0007420 brain development biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0000785 chromatin cellular_component
GO:0005634 nucleus cellular_component
GO:0090694 Scc2-Scc4 cohesin loading complex cellular_component
GO:0000228 nuclear chromosome cellular_component
GO:0003682 chromatin binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-060526-121 Enables chromatin loop anchoring activity. Acts upstream of or within digestive tract development and embryonic morphogenesis. Predicted to be located in nucleus. Predicted to be part of Scc2-Scc4 cohesin loading complex. Is expressed in Kupffer's vesicle; blastoderm; blastodisc; head; and lateral plate mesoderm. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 1. Orthologous to human NIPBL (NIPBL cohesin loading factor).

Ensembl:

ensembl_id ENSDARG00000098272

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00059965 False 8317 mRNA 0.51 45 8005911 8096232
TCONS_00061514 True 854 lncRNA 0.36 2 8093285 8096026

Neighbor

gene id symbol gene type direction distance location
XLOC_030821 FP016143.1 coding downstream 33032 7972759 ~ 7972879 (-)
XLOC_030820 EGFLAM coding downstream 36151 7919878 ~ 7969760 (-)
XLOC_030819 opn4xb coding downstream 108491 7853463 ~ 7897420 (-)
XLOC_030817 pdlim5a coding downstream 161646 7722017 ~ 7844265 (-)
XLOC_030818 NA coding downstream 280636 7725064 ~ 7725275 (-)
XLOC_030823 slc1a3a coding upstream 15118 8111350 ~ 8171625 (-)
XLOC_030824 NA coding upstream 221486 8317718 ~ 8325015 (-)
XLOC_030825 spef2 coding upstream 259415 8355647 ~ 8406192 (-)
XLOC_030826 NA coding upstream 313229 8409461 ~ 8416833 (-)
XLOC_030827 lifra coding upstream 320952 8417184 ~ 8483537 (-)
XLOC_030816 CABZ01069879.1 non-coding downstream 373092 7632695 ~ 7632819 (-)
XLOC_030814 CU856253.1 non-coding downstream 574388 7431425 ~ 7431523 (-)
XLOC_030813 NA non-coding downstream 628506 7376982 ~ 7377405 (-)
XLOC_030830 BX897662.1 non-coding upstream 539036 8635268 ~ 8635392 (-)
XLOC_030831 BX897662.3 non-coding upstream 541572 8637804 ~ 8640000 (-)
XLOC_030832 NA non-coding upstream 544446 8640678 ~ 8644183 (-)

Expression


Co-expression Network