XLOC_033777 (cog4)


Basic Information

Item Value
gene id XLOC_033777
gene name cog4
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007118.7
NCBI id CM002891.2
chromosome length 74282399
location 29024282 ~ 29040707 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00066081
GTGTGTATGTGGGGCTGTCAtggaagaagcagcttcaccgGCTCGTCGTCGCGGTGGTCCGGCGGGGGTCTCCGCCGTGCAGACCGACACTATCGAGGCTCTAACTGAGCTGGAGGATCTGGAGCGGGTCTACGCGCAGCTGTGTGCCGAAGAGGCGGAAGTGCAGGTGGAGTTGGACGCTCTTGTGGGACAACAGAACAACATCGAAACAAAGATGCTCTCCCTGCAGAGGATGGGACCCAACCTGCAGCTGATCGAGGGAGACGCTGTGCAGCTCTCTGGCATGATCAACTTCACATGCAGCCTGGCAGAAAATGTCAGCAGCAAAGTCAGACAGCTGGATCTCACCAAGAAAAGGCTGTACCAAGCGATTCAGCGGGCTGATGATATTCTGGACTTGAAATTCTGCACAGATGGTGTTCAGACTGCCCTGCGGAATCAGGACTATGAACAGGCCGCTGCCCACATTCATCGCTACCTTTCTCTTGACCAGTCTGTGATCGAGCTCAGCAAGCAGGGTGGAGAGGGCAGTGCAGTTGAAGCCAGCCTTGCGTTGCTTCAGGAGGCAGAGCGCAATCTGAAGACACTGGTTACCACTCGTCTGGAGGAAGCAGTTGCCACAGGCGACTTGCCTCAAGTTGAGCGCTTTTTCAAGATCCTTCCTTTACTAGGACTCCATGAGCAGGGACTTGCACGCTTTGCTCAGTACCTTTGCAGTCAGTTGGCCAGTAAGGCAGAGGAGAATTTAATCTTGGCCGTTGGCTCTGATCTCGGTGAACGCAGAGCACCTGTGATCTTTGCTGACACTCTTACACTGCTGCTCGAAGGCATTGCACGCATTGTAGAAACCCATCAGCCAATAGTGGAGACATACTATGGACCGGGCCGCCTGCACACACTTCTCGCGCACCTTCAGAAAGAGTGTGACAAACAGGCTCAGAAAATAGTGGACAAATTCATCCAACAGAGGGATTACAACAATAAGTTTCAGGTTGTCCAGAGCAACATGATGAGGGGCATGACTACGGATAAGATCGAACCCAGAGACCTGGATCCTGTGTTATGTGAGGTTACCTTAATGAACTCAAGAGCTGAGTTGTATTTCCGATTCTTGAGGCGGCGTATAGTCGCTGACTTCGAGGTTGCAGATGCCATGGCGGATGAAGCGGTTATACAAGAGCATCAGCAGAGTTTAGAACAGTTACTGAAGAATTGCCAGCTGAGTCGCACTATGCAGGAGCTGATTGGCTATTACATTCCTATGGAGGAGTATTACATGAGAGAGTCTGTCAACAAGGCCGTTGCGATGGACACCGCTGAGGTGGGACAGCTGAGCTCAAGCGTGGTGGATGATGTTTTCTACATTGTAAAGAAATGCATCAGTCGGGCACTCACCAGCAGCagctctgactgtgtgtgtgccaTGATCAATCATGCAACCAGTGTTCTGGAGACAGACTTCAGGGAGGTGCTAGTATGCAAGTTGCGGGCGGGATATCCCGTCAGTGCTCTGCAGGACCTGCAGCGAGGGGTCAGCAGTGCCGTCAGCCTGATGCAGAGCAGCCTGCAGCAGGGCAAGATAACGAACCTCACACAAACCCTCGGCATTGAGAGCCAGGAGCAAGCCAAGAGCGCATACTTGGTGACCCTCAATAATGTGGAGGTCTGCAGTGAGAATATCAGCACCCTGAAAAAGAATCTCGAGAGTGATTGTGCCAAGCTGTTCAGCCAGGGAGCCAGCTCAGATCATGCCAAGGAGAAGATCGACAGCTGTCTGTCGGATCTGGTCAACACCTCCAGCAAATTCAAAGACCTCCTCCAGGAGGGTCTACAGGAGCTTAACAACACTGCTATCAGGCCACAAGTAAAGCCCTGGATCAGCAGCTTCCTGTCTGTCTCGCACAATATTGAAGAGgaaGAGTTTAGTGAGTATGAAGCCAATGATCCCTTTGTTCAGCAACTCATTGTCCAGTTGGAGCAGCTTATGGCTGAGTTTAAGGTCGGACTGTCACCGGTCATCTATGATACTCTGACTAGCCTGATGACCAGCCTAATTGCAATGGAGATGGAGAAGACTGTGTTCAAATGCACCTTCAGCAGGCTCGGTGGATTACAGTTTGATAAGGAGCTGCGGGCTTTGGTCGCATACTTGTCTTCCGTCACTTCTTGGACCATCCGGGATAAGTTTGCCCGACTCACACAGATGGCAACTATACTGAATCTAGAGAGGGTGTCTGAGATCCTGGATTATTGGGGACCCAACTCTGGACCTTTGACGTGGCGTTTGACCCCGGCTGAGGTTCGCCAGGTCTTGGCTCTAAGGGTAGATTTCCGCAGTGAGGACATTAAAAGATTACGActctaacaaaaaaatatatatatatacttgagaTTTTTATCCTTGGTGTTTGGAGTACTTAAATGGAGGTATGTTATCTCAACATTTGTATACAAAATATTGGCCATGcttttttatgtaataaatgtataaccAGCCAAGTTTTTGGCTCAATTTCTGTCAGTGAACTATTCTAAAGCTTGTACTTTTCTTAAATTATCAGCCCTTAGAATTAAAGGGGCTATATATCATAGACTATGTTTAAGATTCGAAGATGTTCCTGATTAGTATTGAAAAGGTTTTAGTGTAAAGTACTAACAAATGGGTTTTGAGACTATAATGAAACATAACAAGATATTTTTAGAATTTCTAGTTTGCCATTGACTGTGAAAGTCTGTAGAGGGATTTTCATTTGAAGcagtgtttttaatatatataacaaatggACATTTACACACTACGGTGAtccttctctgacctctaaagattTACAGTCTTGTCATCTGTTCACAGGATGCCATTAGATTGCAAAGCATGTGCAAAAATACCCACATTGCTACAAATCCAATTCATTCTCTCAACAGTTttattactttctttcttttaaattgaGCAACACATTTTATTAGGGCTGGGGGAAATAGTTAAAAAAGTTTCAACTTATTTTAGATttagttattatatttaaaaagctttaaattattttctCCATGTTTCAATAAAACGTCAATTAGAGTTTGCATGAATAATTTAGTATACAGCTATATGGctcttattttctttttactaATTCATCATATGTAAACTCCTGATCACTGTTCATTTTTAGAGCTGTcagcagtatttttattaaatctgtaGTCAATGAATCGAATCAAACTGAGTCAATTAGCAGTAGTGGAAAGAggactgaaaaatcatacttaagtaaaattaccattacttgcccaaataTGTAGTAAAagtgtttgttgtaaatattactcaaagtactCCGTTTTCATGCAATTTGTAACattgtaacattctgtagtgcatttaggtATTGTCCAGCAGGCACGCAACGCCATAagatattaatattaggttaggttgtgatgtcaggtgaccaaaattcaatgtctagccagcgtccaaGGACAAAgtcattttgatgtccaataacaacgtcaaatggtgttaatatttggttgattttaggtggtGTTAGAAagggaccaaaatccaacattgagccaacatcttccacacaacgtcaagctgtaacatcattacacgttgacatttggttgattttgagTTGgttgttggacattgacgtcggcctgacattgagttctgacgccaacccgattttcattttcaaacaaaatgcagcgtcgcCACAACGTcattctgacatcatgttgacgtcttgtgcctgctgggtgtttttTTACTGCCATTTTGTTTacatcatcatacagtaaacatttgtCATCtcctcatcagtgacatgcatctaaacagtctttgggtcaatgcgtgtaaagattttggacatcttggacacttttaatgcttccacaaTTTACtgcaattataattataaatccCCC

Function

symbol description
cog4 Acts upstream of or within proteoglycan metabolic process and skeletal system development. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of Golgi transport complex. Is expressed in nervous system; otic epithelium; otic vesicle protrusion; and pharyngeal arch cartilage. Used to study Saul-Wilson syndrome. Human ortholog(s) of this gene implicated in Saul-Wilson syndrome and congenital disorder of glycosylation type IIj. Orthologous to human COG4 (component of oligomeric golgi complex 4).

GO:

id name namespace
GO:0006029 proteoglycan metabolic process biological_process
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum biological_process
GO:0048213 Golgi vesicle prefusion complex stabilization biological_process
GO:0001501 skeletal system development biological_process
GO:0007030 Golgi organization biological_process
GO:0015031 protein transport biological_process
GO:0005794 Golgi apparatus cellular_component
GO:0005829 cytosol cellular_component
GO:0017119 Golgi transport complex cellular_component
GO:0000139 Golgi membrane cellular_component
GO:0016020 membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003674 molecular_function molecular_function

KEGG:

id description
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-060312-33 Acts upstream of or within proteoglycan metabolic process and skeletal system development. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of Golgi transport complex. Is expressed in nervous system; otic epithelium; otic vesicle protrusion; and pharyngeal arch cartilage. Used to study Saul-Wilson syndrome. Human ortholog(s) of this gene implicated in Saul-Wilson syndrome and congenital disorder of glycosylation type IIj. Orthologous to human COG4 (component of oligomeric golgi complex 4).

Ensembl:

ensembl_id ENSDARG00000054264

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00066081 True 3936 mRNA 0.44 19 29024282 29040707

Neighbor

gene id symbol gene type direction distance location
XLOC_033776 dnaaf1 coding upstream 6390 29012033 ~ 29017892 (+)
XLOC_033775 CR376738.1 coding upstream 14147 29009161 ~ 29010135 (+)
XLOC_033774 CR376738.2 coding upstream 17884 29005622 ~ 29006398 (+)
XLOC_033773 dok4 coding upstream 25140 28901786 ~ 28999142 (+)
XLOC_033772 ccdc102a coding upstream 186964 28724910 ~ 28837318 (+)
XLOC_033778 gfod2 coding downstream 4181 29044888 ~ 29052468 (+)
XLOC_033779 sinhcafl coding downstream 12510 29053217 ~ 29062157 (+)
XLOC_033780 NA coding downstream 21468 29062175 ~ 29064397 (+)
XLOC_033781 vrk3 coding downstream 25208 29065915 ~ 29080556 (+)
XLOC_033782 acd coding downstream 39977 29080684 ~ 29094305 (+)
XLOC_033770 BX323591.1 non-coding upstream 562704 28461463 ~ 28461578 (+)
XLOC_033769 BX072554.2 non-coding upstream 765656 28253644 ~ 28258626 (+)
XLOC_033768 BX005056.1 non-coding upstream 1111227 27912938 ~ 27913055 (+)
XLOC_033764 NA non-coding upstream 1191959 27822444 ~ 27832323 (+)
XLOC_033790 NA non-coding downstream 237860 29278567 ~ 29280954 (+)
XLOC_033794 NA non-coding downstream 426431 29467138 ~ 29467407 (+)
XLOC_033795 BX927082.2 non-coding downstream 462167 29502874 ~ 29506147 (+)
XLOC_033797 NA non-coding downstream 519861 29560568 ~ 29631080 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000026_04344703_04357534 GFOD2, COG4 coding CI01000026 null 4344703 ~ 4357660 (+)
bowfin (Amia calva) AMCG00020327 cog4,LOC107577202 coding CM030127.1 CM030127.1 16550086 ~ 16557457 (+)