XLOC_035676 (mmp9)


Basic Information

Item Value
gene id XLOC_035676
gene name mmp9
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007119.7
NCBI id CM002892.2
chromosome length 54304671
location 24281512 ~ 24295947 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00069960
GACACAGCAACACTGCTTCCACTTCATCTGATCTGATCTGAGCACTTGCAAGACAGTTTCTCCAGATTTCTTCTgaatttacttttatatttgcGACTCAAAATGAGACTTGGAGTCCTGGCGTTTCTGGTTCTGGGCACCTGCTCGTTGAGAGCCTGGTGTTTGCCACTCAAATCTGTGTTCGTGACGTTTCCTGGAGATGTGATCAAGAACATGACCAACACACAGCTAGCGGATGAGTATCTGAAGCGTTACGGCTACATCGATGTCCTCCAGAGGAGCGGACTGCAGGCGGTCGTCTCCAATACTAAAGCTCTGAAGAAGCTCCAGCGGCAGCTCGGTTTGGAGGAGACCGGCTTGCTTGACCAGCCCACCGTTGATGCCATGAAGCAGCCCCGCTGTGGCGTGCCGGACATCCGCAACTACAAGACATTCGACGGAGACCTGAAGTGGGATCACACAGATGTCACATACAGGATTTTGAACTATTCGCCAGACATGGAAGCCTCTTTGATCGATGATGCTTTTGCCAGAGCTTTTAAAGTTTGGAGTGACGTCACCCCTCTGACGTTCACACGCCTCTTTGACGGCATTGCTGACATCATGATCTCTTTCGGGAAAGCAGATCACGGTGATCCCTACCCCTTTGATGGAAAAGATGGGCTGCTGGCTCACGCTTATCCTCCAGGTGAAGGCACACAGGGAGACGCTCATTTTGATGACGATGAATACTGGACCCTTGGCTCTGGACCAGCCATTCAAACCCGCTACGGTAATGCTGAGGGTGCAATGTGTCACTTCCCCTTCCTGTTTGAGGGAACATCCTACTCCACCTGCACCACTGAGGGCCGCACAGATGGCCTTCCCTGGTGCTCAACCACCGCAGACTATGACAAGGACAAGAAGTTTGGCTTCTGTCCCAGTGAGCTTCTCTTCACATTTGACGGGAACAGCAATGAAGCACCATGTGTTTTCCCCTTCATTTTTGATGGGAAGAAATATGATTCATGCACTACAGAAGGACGAAATGACGGATATCGCTGGTGCTCCACTACAGCTAACTTTGACACTGATAAGAAGTATGGATTCTGCCCTAACAGAGATACGGCTGTGATTGGTGGAAACTCAGAAGGAGAGCCATGCCATTTTCCATTCACCTTCCTGGGAAACACATACTCATCCTGCACCAGTGAGGGCCGCAATGATGGAAAACTCTGGTGTGGAACTACCAGCAACTATGATACTGATAAAAAATGGGGATTTTGCCCTGATCGTGGATACAGTCTGTTTCTGGTGGCTGCTCATGAGTTTGGACATGCTCTTGGTTTGGATCACTCCAACATTAAAGATGCCCTGATGTATCCCATGTACAAATACGTGGAGGGTTTCCCCCTGCATCGTGACGATATTGATGGCATTCAGTATCTCTATGGACCTAGAACTGGCCCTGAACCCACTGCTCCTCAACCACGGACCACCACTTCCTCTCCAGTTGTGCCAACGAAACCTTCTCCAAGTGACAAAACAACCACTGCTTCCACCACAACTCAGGTGGTCCCTTCAGACGATGCCTGCCAAATCAAGGAGTTTGACGCCATCACTGAAATCCAGAAGGAGCTTCACTTCTTCAAGGACGGGCGCTACTGGAAGATCTCAGGCAATGGTGAACGCAAAGGTCCTTTCATGATCTCTGCGAAGTGGCCTGCTCTCCCAGCTGTCATCAACTCTGCCTTTGAGGACCACCTCACCAAAAAGATCTACTTCTTCTCAGAGAGACAGTTCTGGGTTTACAGTGGAAATGATGTGCTTGGACCACGTAAAATCGAGAAGCTCGGCCTACCAAGCGACTTGGACAAAGTGGAAGGATCTATGCAGAGAGGAAAAGGCAAGGTGctcctgtttaatggagaaaactTCTGGAGACTTGATGTAAAGGCTCAGCTGATTGACAGAGGATACCCTCGATTCACTGATGCAGCTTTCGGTGGAGTGCCCGTTGATTCACATGATGTATTCCTCTACAAGgGATTCTTCTACTTCTGCCGGGAGAGCTTCTACTGGAGAATGAATGCCAAACGGCAGGTTGACCGAGTCGGTTATGTGAAGTACGACCTCCTGAAATGCAGTGACATTCATTCTCTATAGACCTTCGACATCCTAATCTGATGACAGAGCCCTTTTTTAACAGGGAAACCGTTTCTCTTCAGTGTAAAATGTAGCGAGGAAGACACAGACAGAATGTATTAAATTTCAAGTGTCTGTTAAAGggattttgactttaactgttatAGGAAAAGAACAGTTTTAACACTGAAATTATCATAGGCACATGAGACGGGATGTTAGGCATATTTGTCCGTCAGCTTTACCATGgtcttataatttattatttcagcTTCCCACATAACTGCTTTGGTCATGATGGGTTTCCTAATGGCACATTATTGTAGAAAACGAGGCAAAGCCCGTTTGACTTTAGGAATTAACTTTGTGCTTGTAAATGTGTGAGTGGAGTCTCCGCAGGAATGTTGTAGCCGATTTGTTGTGAACAAAGCACCCGTATTCTGCATTGACCCCATTCAGATGTTTTTGAATGCAAAGGTTTATTTTTAGCCTTAGAGCTAATGATGGGGATTGCAGATTTTGCCATATTGTGAAATCATTTGCCTGGtgtaaatgatattattaatattattaatttaatgttcAACCTTccacttatttatatttttatgtttgttgcagtgtttgtttacttaataaatttgtaaacaagatcctttaa
>TCONS_00069961
ATGCTTTTGCCAGAGCTTTTAAAGTTTGGAGTGACGTCACCCCTCTGACGTTCACACGCCTCTTTGACGGCATTGCTGACATCATGATCTCTTTCGGGAAAGCAGATCACGGTGATCCCTACCCCTTTGATGGAAAAGATGGGCTGCTGGCTCACGCTTATCCTCCAGGTGAAGGCACACAGGGAGACGCTCATTTTGATGACGATGAATACTGGACCCTTGGCTCTGGACCAGGTGAGTGTCGTTTTAACTCAAGTAGCTTTGATAAATAGGTTAAGTGGTTTAAAACATAATTTAGCATCGCTCTTTATTATAACAACTGCATAGTGTGCATAGAGGAGCAATAGCTCCCTCTGCAGTTCTGAATGAGTAGTGACGGTTACAAacttttttctttcaaaattgtaattaaaacaatgattattatatatatttattttaaagtaaaatactatttaagatttcttttttaatcttccatgtttattcttattgtttgtgtttattagcaaCTTCTGAGTAAAAATATTTCTTCAccattttgtttttcaatttgaGATAGCATTTTAACATGTCCtttgca

Function

symbol description
mmp9 Predicted to enable metalloendopeptidase activity. Acts upstream of or within several processes, including collagen fibril organization; fin regeneration; and positive regulation of granuloma formation. Predicted to be located in extracellular matrix and extracellular region. Is expressed in several structures, including cardiovascular system; female organism; head; hematopoietic cell; and hematopoietic system. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; anodontia; artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Orthologous to human MMP9 (matrix metallopeptidase 9).

GO:

id name namespace
GO:0090594 inflammatory response to wounding biological_process
GO:0003417 growth plate cartilage development biological_process
GO:0009617 response to bacterium biological_process
GO:0030198 extracellular matrix organization biological_process
GO:0060429 epithelium development biological_process
GO:0030199 collagen fibril organization biological_process
GO:0002633 positive regulation of granuloma formation biological_process
GO:0031101 fin regeneration biological_process
GO:0006508 proteolysis biological_process
GO:0030574 collagen catabolic process biological_process
GO:0035701 hematopoietic stem cell migration biological_process
GO:0033334 fin morphogenesis biological_process
GO:0042060 wound healing biological_process
GO:0031012 extracellular matrix cellular_component
GO:0046872 metal ion binding molecular_function
GO:0004222 metalloendopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008237 metallopeptidase activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
ko04668 TNF signaling pathway
ko04657 IL-17 signaling pathway
ko04670 Leukocyte transendothelial migration
ko04915 Estrogen signaling pathway
ko04926 Relaxin signaling pathway
ko05200 Pathways in cancer
ko05202 Transcriptional misregulation in cancer
ko05206 MicroRNAs in cancer
ko05205 Proteoglycans in cancer
ko05219 Bladder cancer
ko05215 Prostate cancer
ko05161 Hepatitis B
ko05417 Lipid and atherosclerosis
ko05418 Fluid shear stress and atherosclerosis
ko05415 Diabetic cardiomyopathy
ko01522 Endocrine resistance
ko01002 Peptidases and inhibitors

ZFIN:

id description
ZDB-GENE-040426-2132 Predicted to enable metalloendopeptidase activity. Acts upstream of or within several processes, including collagen fibril organization; fin regeneration; and positive regulation of granuloma formation. Predicted to be located in extracellular matrix and extracellular region. Is expressed in several structures, including cardiovascular system; female organism; head; hematopoietic cell; and hematopoietic system. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; anodontia; artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Orthologous to human MMP9 (matrix metallopeptidase 9).

Ensembl:

ensembl_id ENSDARG00000042816

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00069960 False 2785 mRNA 0.46 13 24281512 24295947
TCONS_00069961 True 583 lncRNA 0.37 2 24283595 24291601

Neighbor

gene id symbol gene type direction distance location
XLOC_035675 CT025875.1 coding upstream 130260 24110045 ~ 24151252 (+)
XLOC_035672 cpne5a coding upstream 204668 23916647 ~ 24076844 (+)
XLOC_035674 AL928881.1 coding upstream 217217 24064210 ~ 24064295 (+)
XLOC_035673 CT573357.1 coding upstream 360796 23917588 ~ 23920716 (+)
XLOC_035671 NA coding upstream 374139 23898723 ~ 23907373 (+)
XLOC_035677 ZNF335 coding downstream 692 24296639 ~ 24466515 (+)
XLOC_035678 NA coding downstream 52534 24348481 ~ 24350244 (+)
XLOC_035679 NA coding downstream 121922 24417869 ~ 24692136 (+)
XLOC_035680 NA coding downstream 284923 24580870 ~ 24588948 (+)
XLOC_035681 NA coding downstream 326087 24622034 ~ 24623602 (+)
XLOC_035666 AL929282.1 non-coding upstream 500118 23781005 ~ 23781394 (+)
XLOC_035657 NA non-coding upstream 808646 23462818 ~ 23472866 (+)
XLOC_035682 BX324132.2 non-coding downstream 410604 24706551 ~ 24711139 (+)

Expression


Co-expression Network