XLOC_003719 (gli2b)


Basic Information

Item Value
gene id XLOC_003719
gene name gli2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 43661735 ~ 43713750 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00007195
GTGGCCCACGAGCACCTGAAGGAGCGAGGGTTGTTtggtcttcctcctcctcctggtGCGTCTCCAGCGGATTATTACCACCTGATGGCCGGCCATCGGAACCCGTATGGAGAACTACTGATGCAGGGAGCTGGAGCCGCAGCGGCCGCCGCTCACCTGCCAGAATACTTCACATCAGTGGACGTGTCCCGGTTTCCCAGTCCTCGTATGACGCCCAGGTTGAGCCGTAAGCGAGCGCTGTCCATCTCTCCGCTCTCAGACGCCAGCATTGACTTGCAGACCATGATCCGAACGTCCCCCAACTCTCTGGTGGCCTACATCAACAACTCACGCTCCAGTTCGGCCGCCAGCAGCTCCTATGGACACCTGTCAGTCGGAGGAATCAGCCCTTCGTTCCCGTTCCCACACTCCATTAATCCAGTGGCGTATCAGCAGCTGTTGACCCAGCAGCGAGGCCTCAGTGCGTTCGGACACACGCCGCCGCTTATTCAGCCATCACCAACATTCTCCAGCAGACACCCGCTGAGTCTGTCCACTCTGCCCACGCCAACCACCAATGACACGGAGACCAAGAACTCAAATGGAGAGTCTGCGGTCAGCAGCACAGTCAACCCACTCGGCAACAAGAGGTCAAAGGTCAAGACGGAGTTGGGCGGGCCGCGACCTGTGTCACCCTACTCACCGGAGCACCTGAGCAGTGCACAGGACCTGAAGGAGGACATGGACGACTGTAAGCAGGAGGCGGAGCTTGTGTACGAGACCAACTGCCACTGGGAGGGCTGCAGCAAAGAGTACGACACGCAGGAGCAGCTGGtgcatcacATCAACAATGAGCACATCCACGGGGAGAAGAAGGAGTTTGTGTGCCGCTGGGACGAGTGCTCACGCGAGCAGAAGCCCTTCAAAGCGCAGTACATGCTGGTGGTCCACATGCGCAGACACACCGGGGAGAAACCGCACAAATGCACGttcgAGGGCTGCTCAAAGGCGTATTCTCGTCTGGAGAACCTGAAGACTCACCTGCGTtcacacactggagagaaaccgtacgtCTGTGAACACGAGGGCTGCAACAAGGCCTTCTCCAACGCCTCCGACCGAGCCAAACACCAGAACCGCACACACTCCAACGagAAACCCTACGTGTGTAAGATCCCGGGCTGTACCAAGCGCTATACTGATCCCAGTTCGCTTCGGAAACACGTTAAAACCGTGCACGGGCCCGAAGCACACGTCACCAAGAAACAACGCGGAGATCTGCCGTCCAGACCACATCCGCCGAAGGAGAACGGAGAAAATGAAGCCGGAGCCAAGATGGCGGAGGAGAAAATTGAAGCCAACAGCACTACTAGAGGAGTGGAGGACTACCTGCAGGTCAAGTCTATCAAGACTGAGAACTCAATGATGTATCAGTCCAGCCCTGGTGGTCAGTCATCATGCAGCAGCGAGCCGTCACCGCTTGGCAGTGCCAGCCTCCATGGCGGTGGAGTAGAGCCGGCGGGACTCAGCGGGGGCAGCGTGGGAGATCTGAGTGCCCTGGATGACGTGCCCATTGTGGATTCCACCGTCTCCACAGGAATCCTGGGCCTTCATTTGCGCAAGAACGCCGGCCCGGCCCACAGACTCACACACCTGAAGCAGGAGAAGCTGAAGTCGGTGCGGGACTCGTGCTCCTGGGCAAACACAGCTCCTCCTGCCCCCTGCACCAAACTACCACCCATCAATACTGGTTCTTTATTGGACGGTCTGTGTGATCCAGGGCTTTCCATCTCCAGCCCGCGTCTGGGCGACCTCTGTCCTGGCGAGACTACAGTGTTAAGTCAGTTGGTGGAGCGTCGGGACAGCCTGGCCAGCACTGTGAGCTCTGCGTACACCTTCAGCCGGCGCTCATCCGGAATATCACCATGTTATTCGAGCCGTCGGTCCAGCCAAACATCCCAACCTGGCGGCCGTCACAACAACATCAGCTCTGCTGACTCCTATGACCCCATTTCAACCGATCTGTCTCGAAGGTCCAGCGAGGCCAGCCTATATGGGGGAATCTTCAGCTTGACTCCTGCACAACACTACCGACTTAAAGCCAAATATGCTGCGGCCACAGGCGGAGCACCACCCACGCCTCTGCCTAACATAGACTGCAAGACTCTGTTAGGAGATTCGCATGAAATCCCCATACATCCCCCTTTGGTTCCCAGAAGGTGCAGTGACACCGGCTATGCCAACCGTAGCGTTTTACCCCATGAGGTGACAGCAAACATTACTCGAAGAGCAAGCGACCCAGTTAGACGAATAGCTGCTGAGCAGCATTCGCTCTACAACAGTGTAAACCCGTATCCAACATTACACCCTCTTGCGTCAAGCCGACACTTTTACAGCACGTCTGAGAGTAACGTCAACCGCCAGCAATATCCACCTCGAGCTCCGAGCATTTCTGAGAACGTGATGATGGAAACTCTGCCGGATGATATGGAGAGTTGCAATGGTGTTGAGGATGGTTTGATGATGGCTGATGATGCTGTTCAGTGTATCACAACTCAAAACGCAGATTCCCCTCAACATACAGGCGTAGCGCACCGGAACCAAAGCTTTGGTTCTCCACAACATTGTCATCTCCAGAGACGTCTGGCTTTGGTGGAGGGGAATATGAATGCTGTAGCTAGACAAACAGCCAGCTCTCAGCAGACATTTCCAGGTTCGGCCAATGCCACAAAGATCCCGATGCCGGTGCAGTGGAATGAGGTCAGTTCAGGGACGGTGGATTCATCTCGCAGCCAAACCAAGCAGGGATCCGGGCGGGGAAACctccaacaaaaacaaaacctcaGCTCATTTCTGAATGTCAACTCCAACCAGCAAGTCGGTCTGATGAGCCACAACCTTGCCTTGAGTCCCGTACAGCGCAGTGTTGAGTTTAATTCCCTGAGGATCAATCAGAGGCAGGCTAACGCAGAGTTTCTGCATGGTTACCTTCAGGGTTCTGCTTCGAATGACATCAGTCTTGGTTTGCTAAACCCGTCTGGTAAATCGCTGACTGTACAACCTGGTGGCGTGCAGAATAATAGGGTATGCGCTCAAGCCCAAAGCcatgccacttttccaaataatcaaggaAATTACTCCCAGATGAGCAGCAACCAGCAAGGCTACATCGTAGCGTCCCAGAATGTGAACGGAAACCTGCTCCTACAGCCAAGGCCGCCCACAGAACCCAAACCCTACAGCACGCAGCATTCAGGgccaacaacaactgcagcacaATCCAACTTTAGCCCTGCATACGACACCTCAGAGGCAAGCCCAAAAAAATCCAGCTCCATGTTTTACACCGGCCAGATTCACATGTTTGATTCGAGCGGCGCTATGCCCTGCCCATCTTCAGTGGGCTCCCCTGAAACTAATCAAGTCTCCAGTACGGTGGATTCAAGTGGAGCCGATCCCCCGCAGATTGATTTTGACGCTATGCTAGACGACGGCGATCATTCCAGCCTCATGTCAGGAACTTTAAGCCCCGCCCTCCTGCGCAGCCTATCGCAGAATTCCTCTCGTCTCACCACGCCCAGAAATTCGGTGACGTTGCCGCCGGTGGCCGCAGGCATCAGTAACATGGCCATCGGAGACATGAGCTCCATGTTAACTGCGCTAGCAGAGGAGAGCAAATTCCTCAATATGATGTCATAGAAAAGCAGAAAGCACAACATTTAAAGAGACGGACATTTCTGTGTTTGAAATCGCCTCCTATACAGTCGACTCCCTAAACTGGTGCACTAATATACACAGTGAAgtcaaaatacttttaataacccatctttaataactgacttattttctctttgccatgatgacagcacataatatgagactagatattcttcaagacactagtgttcagcttaacgtcacatgtaaaggctttactagggtaattagggtaaagttaggaaaattaggcaagccattgtataacagtggtttgttttgtagccaactg

Function

symbol description
gli2b Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within central nervous system development and dorsal/ventral pattern formation. Predicted to be active in nucleus. Is expressed in adenohypophyseal placode; central nervous system; neural keel; and neural tube. Human ortholog(s) of this gene implicated in Culler-Jones syndrome; holoprosencephaly 9; and spina bifida. Orthologous to human GLI2 (GLI family zinc finger 2).

GO:

id name namespace
GO:0021534 cell proliferation in hindbrain biological_process
GO:0007224 smoothened signaling pathway biological_process
GO:0048855 adenohypophysis morphogenesis biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0021953 central nervous system neuron differentiation biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0021508 floor plate formation biological_process
GO:0005634 nucleus cellular_component
GO:0046872 metal ion binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050523-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within central nervous system development and dorsal/ventral pattern formation. Predicted to be active in nucleus. Is expressed in adenohypophyseal placode; central nervous system; neural keel; and neural tube. Human ortholog(s) of this gene implicated in Culler-Jones syndrome; holoprosencephaly 9; and spina bifida. Orthologous to human GLI2 (GLI family zinc finger 2).

Ensembl:

ensembl_id ENSDARG00000020884

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00007195 True 3988 mRNA 0.54 10 43661735 43713750

Neighbor

gene id symbol gene type direction distance location
XLOC_003718 CABZ01073015.1 coding upstream 15061 43643158 ~ 43646674 (+)
XLOC_003717 NA coding upstream 125845 43532582 ~ 43535890 (+)
XLOC_003716 slc29a1b coding upstream 203123 43419809 ~ 43458612 (+)
XLOC_003715 vipb coding upstream 247563 43401201 ~ 43414172 (+)
XLOC_003714 sult6b1 coding upstream 273672 43375326 ~ 43388063 (+)
XLOC_003720 ralbb coding downstream 27199 43740949 ~ 43743702 (+)
XLOC_003721 zgc:153431 coding downstream 37513 43751263 ~ 43787153 (+)
XLOC_003722 NA coding downstream 97879 43811629 ~ 43817356 (+)
XLOC_003723 NA coding downstream 107805 43821555 ~ 43822853 (+)
XLOC_003724 NA coding downstream 230132 43943882 ~ 43950660 (+)
XLOC_003369 CR854846.2 misc upstream 27538653 16122786 ~ 16123082 (+)
XLOC_003318 CR450764.6 misc upstream 30949739 12711700 ~ 12711996 (+)
XLOC_003317 CR450764.16 misc upstream 30967472 12693967 ~ 12694263 (+)
XLOC_003316 CR450764.11 misc upstream 30976136 12685304 ~ 12685599 (+)
XLOC_003315 CR450764.18 misc upstream 30981707 12679732 ~ 12680028 (+)
XLOC_003712 CABZ01058277.1 non-coding upstream 364102 43295275 ~ 43297633 (+)
XLOC_003710 CABZ01080006.1 non-coding upstream 584394 43070883 ~ 43077341 (+)
XLOC_003708 NA non-coding upstream 613714 43035558 ~ 43048021 (+)
XLOC_003725 FP016005.2 non-coding downstream 311012 44024762 ~ 44024878 (+)
XLOC_003727 NA non-coding downstream 449580 44163330 ~ 44196871 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000306_00815374_00840697 NA coding CI01000306 null 814998 ~ 840697 (-)