Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_037603 |
| gene name | nr4a2a |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007120.7 |
| NCBI id | CM002893.2 |
| chromosome length | 56459846 |
| location | 5040985 ~ 5046315 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| nr4a2a | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and glucocorticoid receptor binding activity. Acts upstream of or within dopaminergic neuron differentiation; forebrain neuron development; and neutrophil homeostasis. Predicted to be located in cytoplasm and membrane. Predicted to be integral component of membrane. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in brain; dopaminergic neurons; and retina. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human NR4A2 (nuclear receptor subfamily 4 group A member 2). |
| id | name | namespace |
|---|---|---|
| GO:0071542 | dopaminergic neuron differentiation | biological_process |
| GO:0006355 | regulation of transcription, DNA-templated | biological_process |
| GO:0001780 | neutrophil homeostasis | biological_process |
| GO:0021884 | forebrain neuron development | biological_process |
| GO:0071376 | cellular response to corticotropin-releasing hormone stimulus | biological_process |
| GO:0021953 | central nervous system neuron differentiation | biological_process |
| GO:0021954 | central nervous system neuron development | biological_process |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | biological_process |
| GO:0005634 | nucleus | cellular_component |
| GO:0005667 | transcription regulator complex | cellular_component |
| GO:0016020 | membrane | cellular_component |
| GO:0016021 | integral component of membrane | cellular_component |
| GO:0043565 | sequence-specific DNA binding | molecular_function |
| GO:0035259 | glucocorticoid receptor binding | molecular_function |
| GO:0046872 | metal ion binding | molecular_function |
| GO:0003677 | DNA binding | molecular_function |
| GO:0004879 | nuclear receptor activity | molecular_function |
| GO:0003700 | DNA-binding transcription factor activity | molecular_function |
| GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding | molecular_function |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | molecular_function |
| GO:0003707 | steroid hormone receptor activity | molecular_function |
| GO:0008270 | zinc ion binding | molecular_function |
| id | description |
|---|---|
| ZDB-GENE-990415-184 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and glucocorticoid receptor binding activity. Acts upstream of or within dopaminergic neuron differentiation; forebrain neuron development; and neutrophil homeostasis. Predicted to be located in cytoplasm and membrane. Predicted to be integral component of membrane. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in brain; dopaminergic neurons; and retina. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human NR4A2 (nuclear receptor subfamily 4 group A member 2). |
| ensembl_id | ENSDARG00000017007 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00073850 | False | 3656 | mRNA | 0.42 | 8 | 5040985 | 5046315 |
| TCONS_00073849 | False | 3798 | mRNA | 0.42 | 7 | 5040985 | 5046315 |
| TCONS_00073851 | False | 2153 | mRNA | 0.49 | 7 | 5042034 | 5045378 |
| TCONS_00073852 | False | 496 | lncRNA | 0.44 | 3 | 5043087 | 5044088 |
| TCONS_00075290 | True | 390 | lncRNA | 0.48 | 3 | 5044975 | 5045989 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_037602 | NA | coding | downstream | 173546 | 4866100 ~ 4867439 (-) |
| XLOC_037601 | fmnl2a | coding | downstream | 184218 | 4730398 ~ 4856767 (-) |
| XLOC_037600 | galnt13 | coding | downstream | 434522 | 4538527 ~ 4606463 (-) |
| XLOC_037599 | kcnj3a | coding | downstream | 529372 | 4478199 ~ 4511613 (-) |
| XLOC_037598 | FP102171.1 | coding | downstream | 593881 | 4443918 ~ 4447104 (-) |
| XLOC_037604 | cytip | coding | upstream | 206822 | 5253137 ~ 5263947 (-) |
| XLOC_037605 | ACVR1C | coding | upstream | 225209 | 5271524 ~ 5318873 (-) |
| XLOC_037606 | tnfsf13b | coding | upstream | 278700 | 5325015 ~ 5337923 (-) |
| XLOC_037607 | abhd13 | coding | upstream | 298921 | 5345236 ~ 5351017 (-) |
| XLOC_037608 | CCKBR | coding | upstream | 730044 | 5776359 ~ 5805229 (-) |
| XLOC_037589 | NA | non-coding | downstream | 1645464 | 3358397 ~ 3395521 (-) |
| XLOC_037588 | NA | non-coding | downstream | 1760534 | 3265568 ~ 3280451 (-) |
| XLOC_037587 | FP236594.1 | non-coding | downstream | 1886699 | 3153726 ~ 3154286 (-) |
| XLOC_037613 | FQ377643.1 | non-coding | upstream | 1362842 | 6409157 ~ 6409271 (-) |
| XLOC_037614 | NA | non-coding | upstream | 1485234 | 6531549 ~ 6548796 (-) |
| XLOC_037618 | BX842683.1 | non-coding | upstream | 1671362 | 6717677 ~ 6717801 (-) |
| XLOC_037626 | BX942813.1 | non-coding | upstream | 2311504 | 7357819 ~ 7359484 (-) |
| XLOC_037631 | NA | non-coding | upstream | 2452945 | 7499260 ~ 7505531 (-) |
