XLOC_037843 (htr2aa)


Basic Information

Item Value
gene id XLOC_037843
gene name htr2aa
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 25198249 ~ 25255490 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00074286
TAGTTCGCAAAAACTGGGCTGCACTGCTGATTTTGGTTGTGGTCATTGTTACGGTGGCTGGGAACATTTTAGTAATCATGGCCGTAAATCTGGAAAGAAAACTGCAGAACGCCACCAATTACTTCCTCATGTCACTTGCGGTTGCAGATATGCTTCTGGGACTTCTGGTCATGCCAGTCTCCATGGTGACCATTGTGTATGGTTACTCATGGCCTTTCCCTGCATCACTGTGTCCCATGTGGATCTACCTAGATGTGCTCTTCTCCACCGCCTCCATCATGCACCTGTGTGCAATTTCTCTTGACCGCTATGTGGCCATTCGTAACCCCATCCGACACAATCGGTCAAATTCCCGCTCCCGAGCCCGGGCCAAGATTACGGCAGTCTGGACCATCTCTGCAGGCATCTCTATGCCAATCCCAGTGCTGGGTTTGCGTGATCACACCAAAGTTTTCAAGGACGGCAGCTGCCTATTGACTGACAACTCTTTTGTATTGATTGGGTCCTTTGTGGCATTCTTTGTGCCATTGACTATTATGGTGGTGACCTACTTTTTGACTATCAGCGCTCTGCAGAGTGAAGCCACGCTCTGCCTTGACCAACTGGTGCCCAGGCCCAAATGGAGCACAGGTTTAACTCTTAACTTTCTACCAGGACCCTCGTTTTCGCCGTCAGAGAAAAAACTCTTCCTGAGGCGTTCATTGAGCCGGGAGCCAGGAGCAGATTCAGGAGTTGTCACACCTCCTTTTGGACGGCATAACATGCAGTCTATCAGCAATGAACAGAAGGCCTCTAAAGTTCTGGGGGTAGTTTTCTTTCTCTTTGTGGTCATGTGGTGCCCCTTTTTTATAACCAATGTTTTGGCAGTGGTTTGTGAACCGAATGCGTGCAATGCTAATATAATGAACAGACTGTTGAATGTTTTTGTATGGGTTGGTTACCTGTCCTCCGCCGTTAACCCATTGGTTTACACACTCTTCAACAAGACTTATCGCTCAGCCTTCGCGAGATACATCCGATGCCAGTTTCATGAAGAAAAGAAACCGTTACAGTTAATTCTGGTCAACACAATCCCACCGATGGCCTATCAGTCCACACACCTGCCACTCACTGGATCAATAGGCAATGGGGATTTCTCTCTACCCCTTCCTAATAAAAACCACCATCTGTCCAAAAGCGGCAAAAATGAGAGTGTCAGCTGCTTGTGA

Function

symbol description
htr2aa Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; release of sequestered calcium ion into cytosol; and response to drug. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in several cellular components, including axon; caveola; and presynapse. Predicted to be integral component of membrane. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; anorexia nervosa; major depressive disorder; obesity; and obsessive-compulsive disorder. Orthologous to human HTR2A (5-hydroxytryptamine receptor 2A).

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger biological_process
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0051209 release of sequestered calcium ion into cytosol biological_process
GO:0042493 response to drug biological_process
GO:0007165 signal transduction biological_process
GO:0030425 dendrite cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004930 G protein-coupled receptor activity molecular_function
GO:0030594 neurotransmitter receptor activity molecular_function
GO:0004993 G protein-coupled serotonin receptor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-070912-500 Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; release of sequestered calcium ion into cytosol; and response to drug. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in several cellular components, including axon; caveola; and presynapse. Predicted to be integral component of membrane. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; anorexia nervosa; major depressive disorder; obesity; and obsessive-compulsive disorder. Orthologous to human HTR2A (5-hydroxytryptamine receptor 2A).

Ensembl:

ensembl_id ENSDARG00000057029

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00074286 True 1208 mRNA 0.48 3 25198249 25255490

Neighbor

gene id symbol gene type direction distance location
XLOC_037842 esd coding downstream 16552 25171662 ~ 25181697 (-)
XLOC_037841 rubcnl coding downstream 104068 25091633 ~ 25094181 (-)
XLOC_037840 rubcnl coding downstream 108713 25083160 ~ 25089536 (-)
XLOC_037839 dnah7 coding downstream 142527 24951129 ~ 25055722 (-)
XLOC_037838 NA coding downstream 295676 24561034 ~ 24902573 (-)
XLOC_037845 med4 coding upstream 65190 25320680 ~ 25328527 (-)
XLOC_037846 epc2 coding upstream 92324 25347814 ~ 25366541 (-)
XLOC_037847 acvr2aa coding upstream 125268 25380758 ~ 25444091 (-)
XLOC_037848 NA coding upstream 271181 25526671 ~ 25530527 (-)
XLOC_037849 arhgap15 coding upstream 669463 25924953 ~ 25993849 (-)
XLOC_037837 BX571803.1 non-coding downstream 650253 24547879 ~ 24547996 (-)
XLOC_037836 BX571803.3 non-coding downstream 803867 24390887 ~ 24394382 (-)
XLOC_037835 CR538727.1 non-coding downstream 862970 24335163 ~ 24335279 (-)
XLOC_037830 NA non-coding downstream 1012193 24169615 ~ 24186056 (-)
XLOC_037850 NA non-coding upstream 868122 26123612 ~ 26127381 (-)
XLOC_037851 CR932998.1 non-coding upstream 972959 26228449 ~ 26228563 (-)
XLOC_037852 BX942825.1 non-coding upstream 1155492 26410982 ~ 26429616 (-)
XLOC_037853 BX942825.2 non-coding upstream 1179583 26435073 ~ 26435187 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000009_07440170_07459782 HTR2A, HTR2AA coding CI01000009 null 7440039 ~ 7460409 (+)