CI01000009_07440170_07459782 (HTR2A, HTR2AA)


Basic Information

Item Value
gene id CI01000009_07440170_07459782
gene name HTR2A, HTR2AA
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000009
NCBI id null
chromosome length 16003125
location 7440039 ~ 7460409 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000009_07440170_07459782.mRNA
TTTTAAAGAGGACAGAATGAAGCAAACCTCTGGACTCATGGCTGTATGAAAGATGCCATGAAGAAAAGAAGGATATATCACCTCTAACTGAACTTGTTTTTGACAGTCTATCAGTGTTAATAAGGGACATTATGAACTTGCATGCCAACATTTCAAAACCTGTATCCAAAAGCATCTTCATCTCTTCGAACCTGATGCCCTTTGACCCCGACACCTGGACACCGAGCCCGGACATCATGCTGGGTAATGTGGTCCGTAACAGTTCGTTTGGCTGTAACAGAAGTTGGGCTGATACAGAAGCATCTGTCTTCCCCAATCTATCCATCAGCGGCACTTCCAGTGAAAGGAAAGAACAACTGTCATGGCAAAGGTGCAACGGCGAGATGAGTAAAGAGGAGTTAGTTCGGAAAAACTGGGCTGCTCTGCTGATTTTGATTGTGGTCATTGTTACGGTTACCGGGAACATTTTAGTAATCATGGCTGTCAATCTGGAACGAAAATTGCAAAATGCCACCAATTACTTTCTCATGTCACTGGCAGTGGCAGATATGCTTCTGGGACTTCTGGTCATGCCTGTCTCCATGGTGACCATTGTGTATGGTTACTCCTGGCCCCTCCCTGCATCAATCTGTCCAATGTGGATCTACTTGGATGTTCTCTTTTCCACTGCCTCCATCATGCACCTGTGCGCTATCTCCCTGGACCGTTATGTGGCCATCCGGAACCCCATCCGACACAATCGGTCAAACTCCCGCTCCCGTGCCCGGGCCAAAATCACGGCCGTTTGGACCATCTCTGCAGAGGAAAGGCGATATGATATTGAATGCATGAGGGGGAGAGAGACAGAGCTGTTTGAGCACAAGTTGGATATCTGTAAATCAGAAGTAAGGATGAGAAATGTGATGTCAGAAAAAGTTGATAGCATCTCTATGCCAATCCCAGTGCTGGGTCTGCGTGATCACACCAAAGTTTTCAAGGATGGCAGCTGCCTATTGACTGACAATTCTTTTGTGTTGATTGGGTCCTTTGTGGCCTTCTTTGTGCCATTGACCATTATGGTGGTGACCTACTTCCTGACTATCAGCGCTCTGCAGAGTGAGGCTACGCTCTGCCTTGATCAACTGGTGCCCAGGCCCAAATGGAGTACAGGATTCACTCTGAACTTCCTCCCTGGCCCATCATTCTCACCCTCAGAGAAGAAACTCTTCTTGCGGCGCTCGTTGAGCCGCGAGGCGGGGACAGAGTCGGGGGTTGTGATGCCACCTTTCGGACGGCACAGCGTACAGTCCATCAGCAACGAGCAGAAGGCCTCCAAAGTTCTGGGTGTGGTCTTCTTCCTGTTCGTGGTCATGTGGTGTCCCTTTTTCATCACAAACGTTTTGGCAGTGGTTTGCGAGCCGGCGGCGTGTGACACTGATATAATGAACGGACTGTTGAATGTGTTTGTGTGGGTTGGTTACCTTTCCTCTGCCGTTAACCCCCTGGTTTACACACTCTTCAACAAGACTTACCGCTCTGCCTTTGCTAGATATATCCGATGCCAGTTTCACGAAGAGAAGAAACCGCTACAGCTAATTCTGGTCAACACCATTCCACCGCTGGCCTATCAGTCCACACACCTGCCGCTCACTGGATCAATAGGCAATGGGGATTTCTCTCTGCCCCTTCCCAATAAAAACCAACATCTGTCCAAAAGCCGTAAAAATGAGAGTGTCAGCTGCTTGTGAATTCACTCAATGAACTCACAAAATGCCAGCCGTAACCCTGGATTTTCTTCTGAGTCCGTGTTTGGCATTCTATCTTTCTTACCTCTACAGAAATCAGCTCTGATTGGTCTAAAGTATTAGTATTCAAAGCCCAACTGCAGCTATGAACAAACAGCATCACAGTCCATGACTTGATCACAGGGTACTGATACATCAAAAGACGTTCGTCTGACCGGGATCTGTCCTTAGTACCATCAGTGTCAGTTGAATCAATGGGATAAAACTTCTCTGGTTATAAAAATTGTATATAAGTGTTAAGTCAGAGTTTCGGTTTGATGTCAAGACTTTTCATTTTTATGTAGCACTTTATATTCCAGAAGGCAAAGTCTAAAATCATGGGAGTTCAGCTGTGTTTTGTTTACCATGTCAGGTTTTTGAAAACAAGTGTGGATAAAAGTTGTGATGTGACTAGAGTTTTGTACTGTGTCAAACGATTGAGATGCTGTAGCCTCATTCATAAGCTGTTGGTTTATCATTTTACGTTTGCATTCAATGTCATGGAAAAGAACAAGAATCCTATAGAAGCCTGTTTCCACTTCAGAGTAAAAACTAAAAGAGGTAATCGTGAAATTAAGTTTAAAATAAGAA

Function

symbol description
htr2aa Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; release of sequestered calcium ion into cytosol; and response to drug. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in several cellular components, including axon; caveola; and presynapse. Predicted to be integral component of membrane. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; anorexia nervosa; major depressive disorder; obesity; and obsessive-compulsive disorder. Orthologous to human HTR2A (5-hydroxytryptamine receptor 2A).
htr2a Enables several functions, including 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding activity; Gq/11-coupled serotonin receptor activity; and serotonin binding activity. Involved in several processes, including activation of phospholipase C activity; phosphatidylinositol 3-kinase signaling; and positive regulation of phosphatidylinositol biosynthetic process. Located in plasma membrane. Part of G protein-coupled serotonin receptor complex. Implicated in several diseases, including alcohol use disorder; anorexia nervosa; major depressive disorder; obesity; and obsessive-compulsive disorder.

GO:

id name namespace
GO:0016020 membrane cellular_component

KEGG:

id description
K04157 HTR2; 5-hydroxytryptamine receptor 2

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000009_07440170_07459782.mRNA True 2354 mRNA 0.45 5 7440039 7460409

Neighbor

gene id symbol gene type direction distance location
CI01000009_07392574_07395739 MED4.S, MED4 coding upstream 44269 7392481 ~ 7395770 (+)
CI01000009_07361747_07377615 EPC2 coding upstream 61588 7361747 ~ 7378451 (+)
CI01000009_07316335_07346664 ACVR2A, ACVR2AA coding upstream 93375 7316335 ~ 7346664 (+)
CI01000009_07111833_07115320 NA coding upstream 324617 7110351 ~ 7115443 (+)
CI01000009_07101768_07105835 NA coding upstream 334030 7101269 ~ 7106009 (+)
CI01000009_07490344_07493862 ESTD, ESD coding downstream 29839 7490248 ~ 7493862 (+)
CI01000009_07543034_07544161 NA coding downstream 82625 7543034 ~ 7544161 (+)
CI01000009_07545007_07550103 NA coding downstream 84598 7545007 ~ 7550729 (+)
CI01000009_07555667_07623149 DNAH7 coding downstream 95258 7555667 ~ 7623918 (+)
CI01000009_07969738_07973990 NA coding downstream 508735 7969144 ~ 7974033 (+)
G55013 NA non-coding upstream 35704 7404075 ~ 7404335 (+)
G54999 NA non-coding upstream 143764 7296023 ~ 7296275 (+)
G54992 NA non-coding upstream 150186 7289596 ~ 7289853 (+)
G54964 NA non-coding upstream 202525 7237307 ~ 7237514 (+)
G54957 NA non-coding upstream 211463 7227451 ~ 7228576 (+)
G55009 NA non-coding downstream 3719 7464128 ~ 7464458 (+)
G55030 NA non-coding downstream 23809 7484218 ~ 7484503 (+)
G55032 NA non-coding downstream 26404 7486813 ~ 7487030 (+)
G55057 NA non-coding downstream 91463 7551872 ~ 7552121 (+)
G55058 NA non-coding downstream 101140 7561549 ~ 7561817 (+)
G53651 NA other upstream 1191647 6245564 ~ 6248392 (+)
CI01000009_05931829_05943829 KCNH3 other upstream 1507238 5931718 ~ 5943899 (+)
G53388 NA other upstream 1900985 5522242 ~ 5540638 (+)
CI01000009_03202999_03207060 MPC2, MPC2.S other upstream 4231055 3202207 ~ 3208984 (+)
G51529 NA other upstream 4377452 3062033 ~ 3062587 (+)
G56100 NA other downstream 1668891 9129300 ~ 9130286 (+)
CI01000009_09853929_09854476 SAP18 other downstream 2392950 9853929 ~ 9856587 (+)
CI01000009_11761868_11765848 ORMDL1.S, ORMDL1 other downstream 4300377 11761606 ~ 11766944 (+)
G57811 NA other downstream 4473533 11933942 ~ 11935251 (+)
CI01000009_12432736_12435509 NA other downstream 4972149 12432538 ~ 12436017 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_037843 htr2aa coding NC_007120.7 CM002893.2 25198249 ~ 25255490 (-)