XLOC_000405 (slc5a7a)


Basic Information

Item Value
gene id XLOC_000405
gene name slc5a7a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 34243650 ~ 34261993 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000693
GTCTCAATTTCTTTAGGTCTCGATGAATTTCGGTTCTTTAGAAATACAACGTCTTTAGCAGAGAGAGAAGATGAACATCCATGTGGAGGGGCTGGTGGCGATTGTCATCTTCTACCTGCTGATTTTGTTAGTGGGAATCTGGGCTGCATGGAAGAACAAGAACTCCGGCGTGATGGAGGGAACGGATCGCAGCGAGACTATTATGGTCGGCGGAAGAGATATTGGATTATTTGTCGGCGCATTTACCATGACTGCAACGTGGGTTGGTGGAGGTTACATCAATGGTACAGCAGAATATGTATATCTGCCCGGGTTCGGCTTGGCGTGGGCACAGGCTCCCTTCGGATATGCGCTTAGCCTTGTTTTGGGTGGCCTTTTCTTTGCTAAGCCCATGCGCTCTCGGGGTTACGTCACCATGCTTGACCCCTTCCAGCAACTGTATGGAAAGCGGATGGGTGGTCTGCTGTTCATCCCTGCACTAATGGGGGAAATGTTCTGGTCAGCCGCAATCTTATCTGCCCTcgGTGCCACACTGAGTGTGATCATTGACATTGACATCAACATGTCTGTGGTGATTTCGGCTCTTATTGCCATCTTCTACACGTTGGTGGGTGGCCTGTATTCAGTGGCTTACACTGATGTCGTCCAGCTCTTCTGCATTTTTTTAGGACTGTGGGTGAGTGTTCCTTTTGCGCTCTCGAACCCGGCTGTATCTGACATCGGAGTGACAGCAGTGAAGCAGCTCCATGCTAATCAGACCGCATGGCTTGGGAAGATAGAAAGCTCTGACAAATGGATGTGGGCTGACAACTTCTGCCTTCTGATGTTGGGGGGGATTCCCTGGCAGGTGTATTTTCAAAGGGTTCTTTCTGCCTCTTCAGCTACCTATGCTCAAGTCCTTTCCTTCCTGGCTGCCTTTGGCTGCATCATCATGGCTATTCCCTCTGTCCTGATTGGAGCCATAGGGGCTTCCACAGATTGGAACCAGACCTCGTACGGGCCGATTCCTCCCATGCAAAAGGACCAGTCGGACATGATCTTGCCGATTGTGCTCCAGCACCTTTGTCCAGCCTACATCTCCTTTTTTGGTCTGGGGGCCGTTTCTGCTGCAGTGATGTCATCTGCTGACTCATCCATCCTATCAGCCAGCTCCATGTTCGCAAGAAACATCTACCAGCTCGCTTTCCGCCAATCGGCCTCTGACCGTGAGATAGTGTGGGTCATGCGGATCACCATCTTTGTATTTGGGGCTCTCGCGACAGCCATGGCTCTCCTGACCGGGACGGTGTATGGTTTATGGTACCTGAGCTCTGACCTGGTCTACGTCATCATCTTTCCCCAACTCCTTAGTGTGCTTTTCATCCGGGGCACCAACACTTACGGCTCTGTAGCTGGATACTTCTTCGGCTTGATTCTGCGCATTGGCGGAGGAGAACCTTACCTCAAACTACCTCCATTCATCTACTACCCCGGATGGACCATTGAGGAGAAGGTCCATCATTTGACCCATGAGGTGGAATACCTGGTTATGCAGAGGTTTCCTTTTAAGACTGCTTCAATGCTGGCGTCATTCCTCAGCAATGTAGCATTCTCGTATCTGTTTAAATACCTGTTTGAGAGCGGAACTTTGTCAGCTAAATATGATTTCTTGGATGCCGTGGTGGCCCAGCACAGTGCTGAGATCATGGACAAGACCACTCTGGTCAATAAGAACATCATTGGGCTAAATGAAATGGCCCCTGTCAAACCGAGACTCAGTGTTACTTTAGCTGCTACCTTTACTAGGAAAGAAACCCTGACAGAAGAGGAGGACTCCAGCCCGGAGTCACCCATTCACGAAAATGAGTAGATGTTTATGGTCAATCCTGAGAAGAAGACTCCATAATGTGAACAACAGAGCTTcatctgaaaagaaaataattatctGATTTGAATTATGTAATCCATTGACGCCACATCCTTTTCTGGAATTTTCATTACTACCTTTTTGAAGGGAAAATGGGACAGTGTTTGAAACTCTGTTGAGAACGGAAAATAGAAGAACTGGTTTGAGTGATATTCGGAAAAACTGACTTGATGGTGTTTCTTATTCTGAGAAGCTGGTGGACTCCTGATGGTATGTACGAACCCTGAGTGACTTTCCTTTCCCTTCTAAAGAAAATGATGAGACACTGTGATAATCCTGAATATTTGATTgcattaatgggatagttcacacaaaaatgtgatggtatgtttgttttatttttgtccacCGATACAATCAAATATATTTGGCTTTTATTGTTTAAGTGTGGAAAAAACTGGATAAATCTGCCACAGGATAAAAAAGGGAATTTTTATCTCACAAGGGACATAATTGTAAGATATACTGTAATATAAGAACTGTTAGATACAAACAGAAGCAgtaaattatgataaaaatatCAGAATTCTGCATTTCTTTTAAGGATTGCcactttatttgttatttaaatgcaAGTTTAGTAGTGTTTCTGACCTAATTtctcaaaatattaatattacatataaCAATTCAAAGTGTCTTATTAAAAGCTGAATTTGTGAAGGTTAAGttttatataaactaatatataaaCGTATGTTTTAGGAAAAAGTCTAAACTATGTTAACTGGCATATAAGCttactagggctgtgcgattaattggATTTGACATGTTTCGATTAGCTAAATCACAAGAGGCagtgatatgaaatatatatgatttaatttCCCCTGCCCAGGACAAATGCGTGACTCCCGTCTGTGTGTGACaatcttactagccaattgagtgcgAATACctttgttctgcccaatcagaattgcgcaaccgaaCTATGCAGAACACCCACATTTAAACAAGCAAACAGTAAAGCtgtcaaaaacactgatttctttacaatttaaaatagcttCTTTGGATCTtatttctgctagagatactgttaaacaaatgtaaaaaatatataaaaaattgtacATATACCGTaagaacggtatagcagaaaatatttatggttttaaaactttgacttttccaaaccacggtatacattgaaaacggttattgtcctaTGCCTAGCTGTTacaccatatgaaaaaaaaaatatcacaaaggCACCAGGAGGTAACTAACATCATAACTCACTACTGTTTGCTTTAGAGAAAAATTAGGGTTTAATTTCTGagtattcataaacaaatttaaataaaagttggagtaattttatattttttcagttcctcactgcattttagcagtaagaatcTACTATACAGATTGTTGAGCTGAAGCTTTACTAccaaattaaatcacaaatcaaattgaaattgcaatatatgataaaaaaaaaatcactattagatattttccccaaatcgctcAGCCCTAAAACATACActtaaaaattatgtttgcagcttgtttaaactactcatTCAAAATCAGTTGAAACAACACGTTTCTTACgttatttttaagacatttttattttttatatatgttgaATACACTtcaattgtaaaaacaattaatttaacatagttgatttgtgttgggacagcttGAAATAATTGTGTGTAGCCAAGCATTTATTTTAagcatatatataaaaatagttttttggaaaaaatctgaattgtgagaTATGATCTAACAAGAAAAAtcttaaatgtgatttaaatttttAAGGGTCCTGTGTGTACTGTACTtttagtaatttcacttttatggggATAAATATGTTGATTTGATTGCTTTTAAtgtcaaataactaaaaataaacatacactgtaaaaaaaacagggttccttacaattcattcatgttgtgccaagacaaatcgattaagttaacttaacactttttatatatttgtggATTGAGAATTAAGTTAtcccaataaaatctcaagaattttgttgttttggctcaatttaaataagtagtttgaacaagtaaaagtttttttttttttttttttttttgagtataggAAAATGCTAATTTTGAAAGAACATTTCAGACAGCAAATACTATAACATGTAATATACAATATTAGGAACCATAGAATTGTGAGATAAAAAGTTGCAGTTACCTTTTTATTCTGTAATAGAGACAGGCTTCCTTTGAAATATTTGAaactgagtaaatgatggcaggattgtatttttttattctgtgaacTGTCCCTATAATGTTTCTGAATCTGGACTCAGGTCAgtccagaatttaaaaaaaaatgttacagtgATGATGATAATATATCCAATTATAGCTGTATATGAAAAAGAATAATAGGTGTAAGTTCATGTCATGCCATTACTTATGTCGAACTCCCATGGTAGATTTTAGTGCAGATTATCCTATCGTCCTCTCATAAAAATCAAATGTAGCTAAACAGTAATAAGCtgcttaataaatgtataattgtatAACAAGTGACGTGCTTCCCATCTACGAAATACCTTTAAAAACTGTGACATAAGAGTGCACATGTGGCAAATACATTTTTCATGTTCGTAGTGCAATATTAAGATGAACGGGAAGACTTAGAACATGgggaagtgaaaaaaaaaaaaaaaacatacttaatCTTATAATCGCCTTAACTAGCTACATTGATTAGATGGGAGTGATTGGACATTATGCAAACCTGGTTTGTCACTTTGTTGTACTTGAAAATGAATGTAGCAACTGATTTACCAGATGTAATAATAACCTCCAGGGTCTGTGCTGTGTTGacttttatttttgtgatttgcAAAGTCATACGTATGTCTAAAGAAGTCATTGTACCTGGTTTCAGGACGATCTAGCTGCTGTGTTGTTTTGTTGGCTTTAGCGATACAAGaatttgtgtgttgtgtgtgtgtatttatattccAATGAATATATCTATCCAGTATTTCACTAAAATGTAAAGTGTCACTTTACCATTCaacaagcatatatatatataacaatatatttatttgagtTGGTTGGAGCCAGCTacacaaatctatatttatttattatttgtggcCTACATAGAAGAGATAAtaaattttattgttaagacttTCATAGTTGTGTATGATTCATTGTTATATCGTCATGCTCAACAAAGTGTTTAAATCATTTGTTCAAACTCGCTTTCTAA

Function

symbol description
slc5a7a Predicted to enable choline:sodium symporter activity. Predicted to be involved in acetylcholine biosynthetic process; chemical synaptic transmission; and choline transport. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including axon; dendrite; and perikaryon. Is expressed in dorsal habenular nucleus. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 20 and distal hereditary motor neuronopathy type 7A. Orthologous to human SLC5A7 (solute carrier family 5 member 7).

GO:

id name namespace
GO:0007271 synaptic transmission, cholinergic biological_process
GO:0007274 neuromuscular synaptic transmission biological_process
GO:0015871 choline transport biological_process
GO:0055085 transmembrane transport biological_process
GO:0008292 acetylcholine biosynthetic process biological_process
GO:0030424 axon cellular_component
GO:0030425 dendrite cellular_component
GO:0045202 synapse cellular_component
GO:0005886 plasma membrane cellular_component
GO:0043204 perikaryon cellular_component
GO:0016020 membrane cellular_component
GO:0022857 transmembrane transporter activity molecular_function
GO:0005307 choline molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-090313-273 Predicted to enable choline:sodium symporter activity. Predicted to be involved in acetylcholine biosynthetic process; chemical synaptic transmission; and choline transport. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including axon; dendrite; and perikaryon. Is expressed in dorsal habenular nucleus. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 20 and distal hereditary motor neuronopathy type 7A. Orthologous to human SLC5A7 (solute carrier family 5 member 7).

Ensembl:

ensembl_id ENSDARG00000074860

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000693 True 5150 mRNA 0.37 8 34243650 34261993

Neighbor

gene id symbol gene type direction distance location
XLOC_000404 arl6 coding upstream 9594 34203817 ~ 34234056 (+)
XLOC_000402 epha6 coding upstream 42455 33969015 ~ 34201195 (+)
XLOC_000403 dre-mir-734 coding upstream 120678 34122880 ~ 34122972 (+)
XLOC_000401 CT573012.1 coding upstream 276377 33967157 ~ 33967273 (+)
XLOC_000400 CU915566.1 coding upstream 508516 33735018 ~ 33735134 (+)
XLOC_000406 kctd12.2 coding downstream 33932 34295925 ~ 34297403 (+)
XLOC_000407 CR848003.1 coding downstream 138247 34400240 ~ 34400354 (+)
XLOC_000408 NA coding downstream 188666 34450659 ~ 34454447 (+)
XLOC_000409 klf12a coding downstream 234862 34496855 ~ 34558804 (+)
XLOC_000410 gpalpp1 coding downstream 423412 34685405 ~ 34694365 (+)
XLOC_000394 NA non-coding upstream 724827 33517802 ~ 33518823 (+)
XLOC_000390 BX322647.1 non-coding upstream 1026932 33215241 ~ 33216718 (+)
XLOC_000414 NA non-coding downstream 595375 34857368 ~ 34861057 (+)
XLOC_000415 NA non-coding downstream 772301 35034294 ~ 35093512 (+)
XLOC_000421 NA non-coding downstream 1634399 35896392 ~ 35898437 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000049_03593799_03605097 SLC5A7 coding CI01000049 null 3593727 ~ 3606491 (+)