XLOC_004710 (bambia)


Basic Information

Item Value
gene id XLOC_004710
gene name bambia
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 23424108 ~ 23430356 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00009334
TCCGATCAGTGATCCGCTGCTTCGCGATCGGGGATAGTTGCCCTTGTGGAAACTTGTTTGTGTTATTTCACGAGTCCGTTTGCgttttatatgtgtttgtgtgtttttcatcGCATGGCGGATTGGTTTGGTTACACACGGGGAATGTTTCTCCACTCGCGCTAGTTTCGGATCCTCCGATGGAACAAGACGCGAGCCTTTTCTGCGCCCGTTTGATTTTTGGATACAGTGTAGATCACAGATCCCTGGGAATGCAGTAATAAATGTAGGACATATGTAACGAGTCCTCTCAAACCATTCGGAGGGTCTTGCCACGGGGTATCAAGACAAGGAAAAGCAGCCGTAAATGGATCGCCTGGTTTCTCTGTGGTTTCAGCTGGAACTTTGTGCGATGGCTGTTCTTCTCACGAAAGGAGAGATCAGGTGCTACTGTGACGCACCGCACTGCGTTGCCACCGGATACATGTGTAAATCAGAGCTCAACGCTTGCTTTACTAAGGTCCTGGACCCTCTTAACACAAACTCACCTTTAACACACGGCTGCGTGGATTCGCTTTTAAACTCTGCAGACGTGTGCTCTAGTAAAAATGTGGACATTTCAAGTGGAAGCTCCTCTCCTGTGGAGTGCTGCCATGATGATATGTGTAACTACAGGGGTTTGCATGACCTCACACACCCCAGAGGGGACTCAACAGACCGATACCACAGCTCCAATCAGAACCTGATCACAAGGGTGCAAGAGTTAGCGTCTGCTAAAGAGGTGTGGTTCCGGGCGGCGGTGATAGCGGTTCCCATCGCGGGTGGGCTTATCCTGGTTCTGCTGATTATGCTGGCGTTGCGAATGCTCCGTAGCGAAAACAAGCGTCTCCAGGCACAGCGCCAGCAGATGCTTTCTCGCCTGCATTACAGCTTTCACGGACACCACCATGCCAAGAAAGGCCACGTGGCTAAGTTGGACTTGGAGTGTATGGTGCCGGTAACGGGACATGAGAACTGTTGTCTGGGCTGCGATAAGCTGCGGCAGACGGATTTGTGCACTGGAGGAGGAAGCGGGGGTGAGCGTCTCCTATCTCTGGTACACTGGGGGATGTACACGGGGCACGGAAAGCTGGAGTTCGTATGACTACTCAGAGCTTCTTTGTTAGGGCACAAAAGGGTAACTGTGTAGTTTGCTGtcgtaatgttattattatcggCGTGTTATTTTATTGTCTCCAACGAGAGCAAAGACATTTCAAGGACACAATTCATtgtgttttctcaaaaaaagagcACTTTACTTGAATTAGAATGGCCGGTCTCTGTGGGGGGCTGTGGTGAATATGAAAAGGGTGGAGCTTATGGACTGCAAGCCCCACCTCCTTCCCTCTCTGGATCCTGGAATGACACTGAAGGATTCGTTAAGACGGTCTTATTTTGCACATTTGTATAAAACGGACTTGATGATTAAAGTTGTAAGGTCGCAGTCTGCGCCCTTTTTTGAAGAATTTTACACTGACACCAGGGTACAGATAAGGTTTGTTGTAGTCAAATTGTATGAATAAAAGATTCAATCTTGACTGTAACAAA

Function

symbol description
bambia Predicted to enable frizzled binding activity. Acts upstream of or within dorsal/ventral pattern formation; negative regulation of BMP signaling pathway; and platelet activation. Predicted to be integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; digestive system; germ ring; optic cup; and pectoral fin bud. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human BAMBI (BMP and activin membrane bound inhibitor).

GO:

id name namespace
GO:0007179 transforming growth factor beta receptor signaling pathway biological_process
GO:0090263 positive regulation of canonical Wnt signaling pathway biological_process
GO:0030168 platelet activation biological_process
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway biological_process
GO:0030514 negative regulation of BMP signaling pathway biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005109 frizzled binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-010416-1 Predicted to enable frizzled binding activity. Acts upstream of or within dorsal/ventral pattern formation; negative regulation of BMP signaling pathway; and platelet activation. Predicted to be integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; digestive system; germ ring; optic cup; and pectoral fin bud. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human BAMBI (BMP and activin membrane bound inhibitor).

Ensembl:

ensembl_id ENSDARG00000055381

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00009334 True 1569 mRNA 0.48 3 23424108 23430356

Neighbor

gene id symbol gene type direction distance location
XLOC_004709 waca coding upstream 8047 23371542 ~ 23416061 (+)
XLOC_004708 BX927205.1 coding upstream 313831 23110163 ~ 23110277 (+)
XLOC_004707 NA coding upstream 384017 23037447 ~ 23040091 (+)
XLOC_004706 rab18a coding upstream 490584 22921477 ~ 22933524 (+)
XLOC_004705 afap1 coding upstream 507794 22823219 ~ 22916314 (+)
XLOC_004711 NA coding downstream 24073 23454429 ~ 23605722 (+)
XLOC_004712 BX005058.1 coding downstream 146910 23577266 ~ 23577391 (+)
XLOC_004713 NA coding downstream 219536 23649892 ~ 23651056 (+)
XLOC_004714 mtpap coding downstream 233979 23664335 ~ 23674621 (+)
XLOC_004715 jcada coding downstream 332610 23762966 ~ 23796707 (+)
XLOC_004701 NA non-coding upstream 804986 22618388 ~ 22619122 (+)
XLOC_004700 CR925753.1 non-coding upstream 845578 22578404 ~ 22578530 (+)
XLOC_004696 NA non-coding upstream 1119267 22258962 ~ 22304841 (+)
XLOC_004716 NA non-coding downstream 348596 23778952 ~ 23779177 (+)
XLOC_004717 NA non-coding downstream 382174 23812530 ~ 23935333 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000063_04345980_04349791 BAMBI, BAMBIA coding CI01000063 null 4345980 ~ 4350236 (+)