igfbp6b (igfbp6,igfbp6b,LOC108433391,LOC107697925,LOC107599019)


Basic Information

Item Value
gene id igfbp6b
gene name igfbp6,igfbp6b,LOC108433391,LOC107697925,LOC107599019
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047610.1
NCBI id CM018556.1
chromosome length 25111544
location 20661406 ~ 20666057 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026920287.2
ccatgctctctctccctctctctctatcaccgCCTTTCAGATCTTTAAAAGCTGCTGCTCTGTGCGTTTCTCAGGATCGTGTCCTCTGGCACTCTGGCTGAACGGAGCACCGAGCaaggagaaaagagaagcaGATCTCCAGAAATAGCATCGGCCAAGGAGCACGTACGAACGGCGAAGGAGCATGGAGTCCCACAGCGCAAAGATGCCTTTGCTCTTGAACTTGATGGCTGTTGTCCTGTTGCTCATCGCTCACTGTGGATCCTGGACTCTGGCCAGTCGCTTGGGTCCACATAAGATCTGCCCGTCCTGCAAAGACTCTCGAGCTTCTCGGGACCCTGTCGGGGCAGCCAACACAGCTGTGCTGGCTTTAGGGGAGCCATGCGGCGTTTACACGCTGAGCTGTGCCAAGGGCCTGCGCTGCATGCCTCCACCACGCGACCACAGCCCACTCCAGGCTCTGCTGCAGGGCCGAGGCGTATGCACCAAGCAGATCAGGACGAGTCCCACCGAAAAACCCCACCCTACAGGTCCACATCCTTCCCACAGCGGTGAAATTGAAAAGGCTCCGTGCCGGAAGCTGCTCAACGCCGTGCTGCGTGGCCTCGAGCTCACTGTTTTCCAGTCCGATCGTGACATCTACATCCCCAACTGCGACACTCGTGGCTACTACAGGAAAAAGCAGTGTCGGTCCTCTAAAGGCATGCAGCGCGGCCACTGCTGGTGCGTGGACGAATTAGGCGTCACCCTACCATCCCAAGCTGGAGACGACGGCACTTTACCGTGTGATGGAGAGTGAGACGGGGCACGCGGTGCCACAATTCTGAGccaggaggaagaagaggaagaggaggggagGGGCGTAAGGGAGACGGGAGGACAAGCCGCTCGTGCTAGACACTGCCTGGCCAGGAGACACCAGGGGAAAACCACTCAACACGGGAAACACACGCTCTTCGCTCAAACACTCCATCCACCGCAACAACTGAAGGTTCACGTCACTGCCATACGCCTCTGCAGGTCCTGCAGTGTGTAAGCACAGAGCCAATGAGACACTCCATCACTCCACCCGTGGTAGATCACTTCGAAACGAGACTCTACACCCTGGCCACTTAGTAGCGTCCATTTTTCTGTGATAGCCATCACTGCCTGTGTCTTGTGTATCTCTGAGTAGGCCGTAAATACTGTTAAAGCGGGCGTGGGCGCCATTTTTCTCTCCGCCTCCCCTGCcatcccctctccctctctccaaaGATACACTGACTAAATTAACATGTACGAAAGCAAATTATGcctttacatttaatttattccGGAGTATTATTGTATTTCCTTGGAGACGTTCATGTATTTCATGTAACCAAGACATCAACTCTGCCGTGTGTGCACGTGATTTGGGAAAACATTCAGTCCTTTCTGTTGTGACAGTCTGAGCATTAATACATACATTGTTTGTAcataaatcctttttttttttttgtggttgcCATTGGGTGATAGGTTCTTGAAAGCTGATGGCTATTACTCTATCTGAAAaggcatatttttatatacttcaatataatattttatatatagattGATGCTTTATTTAAAGAACTACAATaccatgtatttttatattgtcaacattgtttttttttttcattgtcaaGTTTAATTTCATGCTGAAAGTGAACACCGGGCTTTGATGGCACATTTtaggaattaaaaaataaataaataacacacccTTCAGATATATTGTACTACTATACATGTTTTAGCAATtattctttcatttcctgaactgtaatatttatgttgATCATTCAGAATTGGTATATGTTCCGATTGTCATTCCAAAAAAATATGGATATCTATTTTCTCACTCCAAAatgcacagagaaaaaaatgctgaaaatgaaagTGCACAAACATTCATACTTCTCTTGTTGTATCGGTGTGTGTGCCAGTGATCGCAGGAGGCTCTGCAAAGCCGCAAAGTAcaagaactttaaaaaaaaataaagaacaaatagCTATATTACTATTATAAGTAACAATGTACTGTGTCTTATTCGAAAGCTCCattaaaatgaaactaaatgtaaGGTGCATATATAATGTTTGCCTCAGATTTATGATTAATATTGGACAGATTGAAgtggtttattttcctataacagcatatcttgaagtgttttattcctcttatccacAGCATATTCCCTAAACTGACAATTGCttgttaattttattcattaaagtatGAAGATGTTATTCACCAAATAAGAAAATTATTAGTGTGGGCAAATTGCCatggtctaagaggaataaatctgtttattattacatttaatgttgtggaatgtccgcgCAAAACAATTAGTTCCTTTAATGACCTACGTTATAATGGCTATATAACATCCCATCACCAGCATTTCTtgcatgttaccaagaaactgcagaACACAAAGTCTTCTGACCTATAGACTTTCCCgtgtagggggaaaaaagttacagctttacccctgactgt

Function

symbol description
igfbp6b Predicted to enable fibronectin binding activity; insulin-like growth factor I binding activity; and insulin-like growth factor II binding activity. Predicted to be involved in regulation of insulin-like growth factor receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in obesity. Orthologous to human IGFBP6 (insulin like growth factor binding protein 6).
igfbp6 Enables identical protein binding activity and insulin-like growth factor II binding activity. Involved in cell migration and positive regulation of stress-activated MAPK cascade. Part of insulin-like growth factor binary complex. Implicated in obesity. Biomarker of breast cancer; in situ carcinoma; leiomyoma; and neovascular inflammatory vitreoretinopathy.

NR:

description
PREDICTED: insulin-like growth factor binding protein 6 paralog B2 isoform X1

GO:

id name namespace
GO:0001558 regulation of cell growth biological_process
GO:0005576 extracellular region cellular_component
GO:0005520 insulin-like growth factor binding molecular_function

KEGG:

id description
K23579 IGFBP6; insulin-like growth factor-binding protein 6

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026920287.2 True 2521 mRNA 0.44 4 20661406 20666057

Neighbor

gene id symbol gene type direction distance location
lima1a LOC108275931 coding upstream 50693 20586167 ~ 20610713 (+)
copz1 copz1,LOC107664248 coding upstream 116609 20537706 ~ 20544797 (+)
hoxc1a NA coding upstream 214424 20439254 ~ 20446982 (+)
hoxc4a hoxc4,hoxc4a,LOC108433407,LOC103034018,LOC107714997,LOC107598886,LOC107664204 coding upstream 247545 20411373 ~ 20413861 (+)
hoxc5a hoxc5 coding upstream 258863 20399696 ~ 20402543 (+)
pip4k2ca pip4k2c,pip4k2ca,LOC107598997,LOC107714989,LOC107664235,LOC107697923,LOC107593957 coding downstream 2056 20668113 ~ 20680070 (+)
LOC113530755 gpr182,LOC108275868 coding downstream 18308 20684365 ~ 20686778 (+)
LOC113530407 gpr182,LOC108275868 coding downstream 23129 20689186 ~ 20691614 (+)
tspan31 tsn31,tspan31,LOC107599072,LOC107593953,LOC108433386 coding downstream 53808 20719865 ~ 20729933 (+)
march9 march9,LOC107593952,LOC107599679 coding downstream 71687 20737744 ~ 20751871 (+)
G258162 NA non-coding upstream 4339 20611541 ~ 20657067 (+)
G258156 csad,LOC107599458,LOC107706996,LOC107697858 non-coding upstream 84617 20567790 ~ 20576789 (+)
G258097 hoxc9,hoxc8,LOC107714926,LOC107664222,LOC103032829,LOC107593970 non-coding upstream 274593 20369995 ~ 20386813 (+)
G257803 kansl2,LOC107716132,LOC107591080 non-coding upstream 552180 20108390 ~ 20109226 (+)
G257802 kansl2,LOC107716132,LOC107687436 non-coding upstream 557366 20101008 ~ 20104040 (+)
G258275 LOC108276173 non-coding downstream 16313 20682370 ~ 20756538 (+)
LOC117599265 NA non-coding downstream 30928 20696985 ~ 20699668 (+)
LOC117599266 NA non-coding downstream 42058 20708115 ~ 20711958 (+)
G258362 NA non-coding downstream 120185 20786242 ~ 20790145 (+)
LOC117599282 NA non-coding downstream 242759 20908816 ~ 20911082 (+)
LOC113530729 hnrnpa1,LOC108275985,LOC108275986,LOC107707002,LOC107714994 other upstream 147211 20510244 ~ 20514195 (+)
G258096 hoxc6,hoxc6a,LOC107593966,LOC108433405,LOC107664205,LOC107714999,LOC103034651 other upstream 262692 20390809 ~ 20398714 (+)
si:ch73-206d17.1 LOC108275771 other upstream 956343 19625529 ~ 19705063 (+)
G257622 LOC108276210 other upstream 1182511 19478302 ~ 19478895 (+)
pkig NA other upstream 1438847 19198426 ~ 19222559 (+)
ubxn10 ubxn10,LOC108275535,LOC108433381,LOC107385551,LOC107699345 other downstream 237048 20903105 ~ 20907459 (+)
si:ch73-290k24.5 LOC108275473 other downstream 562263 21228320 ~ 21238999 (+)
LOC117599233 NA other downstream 871988 21538045 ~ 21542427 (+)
LOC113530514 LOC108275916 other downstream 2005341 22671398 ~ 22680542 (+)
LOC117599309 NA other downstream 2705687 23371744 ~ 23383653 (+)

Expression


Co-expression Network