hsd11b2 (hsd11b2,LOC107755122,LOC107548951,LOC107657103)


Basic Information

Item Value
gene id hsd11b2
gene name hsd11b2,LOC107755122,LOC107548951,LOC107657103
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047619.1
NCBI id CM018565.1
chromosome length 19570078
location 5499975 ~ 5517575 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026937585.2
ATGGACGACTATGCCCTGTCCTTCTGGATTTACATGGGAGTGATGTCTGTGTTTGTTGGAGGCACGCTGAAGAAGTTCCTGGCATCCCACGTCAGTGCCATGCCCTCGCTCGTGGCATGGCTGGGTGCCACGCTGCTGGTGGAGAGGCTGTGTGCTATGTGCATGCCTGCTGTGCTGGCACTTGCTGTCTTCTGTGCCACCTGTTGGCTCTACTCGCTGTGGGCTGCCCCTTCACCGGTCCTGCCTGTCGAAGGCAAAGCAGTTTTCATCACAGGGTGTGACTCAGGATTTGGGCATGCTACGGCAAGGCGTCTGGACGCTATGGGGTTCCAGGTGTTCGCCACGGTATTGGACGCAGATGGTGAGGGGGCCAAGCGTCTGAGGAGTAGCTGCTCTCCTCGCTTGACCTTGCTTCAGGTGGACATCACTCAGCCACAGCAGGTTCAACAGGCTCTGCTCAACACCAAGGCCAAGCTGGGCATGAATGGACTTTGGGCTCTGGTGAAcaatgcaggagtgtgtgtaaactTTGGAGACGCCGAGCTCTCTCTCATGTCTAACTACAGAGGCTGCATGGAAGTAAATTTCTTCGGAACCCTCTGCATCACCAAGACCTTCCTCCCTCTGCTGAGACAAAGCAAAGGCCGAATAGTAACCATCTCAAGTCCTTCAGgtgaacAGCCTTTCCCATGTCTAGCGTCCTATGGGGCCTCAAAGGCAGCACTAAACCTCTTCATTAATACTCTCCGTCATGAGCTGGAGCCATGGGGGATCAAAGTGTCCACGATATTACCTTCTGCCTTTAAAACAGGTCAGAGCAGTAACACCGAGTACTGGGAGAAACAGTACCAGCACCTCCTTCAGAACCTGTCACCGAGTCTTTTAGAAGAGTATGGTGAAGATTACATCATGGAGACCAAGGACCTCTTCCAGAATTATGCCAAATCAGCCAACGAGGACCTGAGCCCTGTCGTTAACACCATTGTGGAGGCACTGCTATCGCCGCAGCCTCAGGTACGCTACTATGCCGGGCCTGGTGTCGGCCTTATGTACTTCATCCACAGCTACTTCCCCCTGAGCATCAGTGACAAGTTTCTGCAAAAGCTATTTCTGAAGAAGAAAGTGATACCGCGTGCACTCAGGAAACAGAATGAGCTGAACCTCATCAAGGACAACAACAACGAcatcatcagcaacaacaacaacatcaccaGTATGGAGTAAACCTATTGTAGCTCCATGTATATAAAAGATGCTAGAGGACCACTGTAATCCATTCATAGTGACCCAATGCCaatatgtgtatttgtttttgtgctgttttatataatgtataatgttttttcgttttttggtttggttttttttgtcattttgaaggGATTGTTGAATGGGTTGCTTTCTGAGTAACTATTAAAAACCATTTTGATAGAAATTAAAATGTGGCTTCCCCTTAATATCAGCTGATCCATTCCCTCCAACTTCTTTGGTAATATTAAATTTCACTATGTGATAACACTAGATGTGTATAGTTCATACACCTTCCATTTTTTTACTTGCCTTGGATACTCAACAGATCATAGACTTTGCTTACAAAAGTCCTTCAGAAGTCTTTGAATCAACAGTGCACACCACTGAGCTACATTCTTAACCTCAGGTTCATAAAACTCACACCATTGCTGCTACTGAATGCAAAATCCATTCATGGTTCTACTTCCAATTCATCAGATAAGTTCATCTACTTCATCTACTTTTTTGAGATAACCTGAAACTTCATTTCCTGCTTACTTAGCCAGCTACAAGCAATAGAATGTCCACCCATAGTCACAATCTCctgtaaataattcaatttttgtTAAGCAGATCAAGCAGATCACCATTTTTCTTCCAGTTTTACTTCccggtttgtttgttttgattttccaTGGCACCATTATTACtacaaatcaaaaatatttattcctGTTTCTTTATGAATCATATAAACTGTgaatttttatacaaaaaaattaaaagaaagaaaatgtaaa

Function

symbol description
hsd11b2 Predicted to enable 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity. Acts upstream of or within cortisol metabolic process and multicellular organismal response to stress. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; cardiovascular system; digestive system; eye; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in apparent mineralocorticoid excess syndrome; hypertension; inherited metabolic disorder; obesity; and type 1 diabetes mellitus. Orthologous to human HSD11B2 (hydroxysteroid 11-beta dehydrogenase 2).

NR:

description
11-beta-hydroxysteroid dehydrogenase

GO: NA

KEGG:

id description
K00071 HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026937585.2 True 2030 mRNA 0.44 5 5499975 5517575

Neighbor

gene id symbol gene type direction distance location
slc12a4 slc12a4,LOC107563468,LOC107740471,LOC107696691,LOC107548948,LOC107755124,LOC107657107 coding upstream 108834 5367548 ~ 5391141 (+)
slc6a2 slc6a2,LOC108443369,LOC106562417,LOC107713067,LOC107563470,LOC107657091,LOC107548932,LOC107755047 coding upstream 156003 5315829 ~ 5343972 (+)
lpcat2 lpcat2 coding upstream 193894 5293211 ~ 5306081 (+)
mmp2 mmp2,LOC107755129,LOC107563472,LOC107696695,LOC107713064,LOC107548946 coding upstream 212787 5267872 ~ 5287188 (+)
irx6a irx6 coding upstream 292855 5201533 ~ 5207120 (+)
agrp agrp,LOC108432372 coding downstream 22138 5539713 ~ 5543335 (+)
galr1b galr1b,LOC108259125,LOC108432392,LOC107548937,LOC107755042,LOC107740459,LOC107696670,LOC107563492,LOC105899736,LOC107657076 coding downstream 55634 5573209 ~ 5606016 (+)
nfatc3a nfatc3,LOC108432391,LOC107548920 coding downstream 135274 5652849 ~ 5727629 (+)
LOC113540863 kctd19 coding downstream 249313 5766888 ~ 5779071 (+)
mybpc3 mybpc3 coding downstream 484930 6002505 ~ 6046718 (+)
G360540 NA non-coding upstream 89328 5410427 ~ 5410647 (+)
G360442 NA non-coding upstream 450074 5048460 ~ 5049901 (+)
G360443 NA non-coding upstream 452313 5047176 ~ 5047662 (+)
G360433 NA non-coding upstream 553565 4946207 ~ 4946410 (+)
G360245 NA non-coding upstream 840617 4615154 ~ 4659358 (+)
G360590 NA non-coding downstream 137750 5655325 ~ 5655815 (+)
G360592 NA non-coding downstream 142610 5660185 ~ 5660502 (+)
G360597 NA non-coding downstream 147711 5665286 ~ 5665521 (+)
G360892 NA non-coding downstream 454089 5971664 ~ 5972079 (+)
LOC117596024 NA non-coding downstream 543454 6061029 ~ 6062571 (+)
fto fto other upstream 735089 4586607 ~ 4764886 (+)
cylda cyld,cylda,LOC107551493,LOC107657079 other upstream 1732261 3713652 ~ 3767714 (+)
cebpa cebpa other upstream 2199292 3245710 ~ 3300683 (+)
cilp cilp,LOC107670750,LOC107750479,LOC107554910 other upstream 2676637 2785627 ~ 2823338 (+)
igdcc4 LOC108259659 other upstream 2805688 2636289 ~ 2694287 (+)
lgr4 lgr4,LOC107700365,LOC107740414,LOC107554901 other downstream 813660 6331235 ~ 6404554 (+)
coro2ba coro2b,coro2ba,anp32a,LOC107755090,LOC107755092,LOC107663971,LOC107740437,LOC107700478,LOC107557695 other downstream 1428718 6946293 ~ 7005078 (+)
znf536 znf536,LOC107556245,LOC107696660,LOC107691894 other downstream 2447626 7965201 ~ 8140621 (+)
slc25a44b s2544,slc25a44b,slc25a44,LOC108438536,LOC107730245,LOC107698229 other downstream 3719614 9237189 ~ 9242763 (+)
serinc4 serinc4,LOC107701272,LOC107695356 other downstream 4753044 10270619 ~ 10291531 (+)

Expression


Co-expression Network