AMCG00006643 (braf)


Basic Information

Item Value
gene id AMCG00006643
gene name braf
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030134.1
NCBI id CM030134.1
chromosome length 29342575
location 12859177 ~ 12872555 (-)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00006643
ATGGCGGCGTTGAGCAGCGCCGAGTCCCCACCGCCCGTCTTCAACGGAGACGCCATGGACCGGGATCCGGACCGGGAGCGGGGACTGGCGGAGCTGGGTGCGGGGCTCGACCCCATCGGGTCCGGGGGGATGCCCGGGGGACACCAGGACATTCCCGAGGAGGTGAGCGGGGGTGACGGGGCGCCCGGGCGGCGGGGGGATCAGGTATGGAATATCAAACAAATGATAAAATTAACACAGGAGCACTTAGAAGCACTGCTGGATAAGTTTGGTGGTGAACACAACCCCCCATCAATATACCTGGAGGCGTACGAGGAGTACACCAGCAAACTAGATGCTCTACAACAAAGAGAACAGCAGCTACTGGAGGCCATAGGGAATGGAACGGATTTCTCCTGCTCCTCTCCTACCCTCTTGGATGTGAAGCTCCCAGGAGGACAGGGCTTCCCCATGGCACCTACCACCCTCGCTGTTCTGCAGACGCCCTCAGACGCTGCTCGCAATAACCCGAAGTCACCCCAGAAACCCATCGTCCGGGTCTTCTTGCCCAATAAGCAAAGAACTGTGGTCCCAGCTCGTTGTGGGATGACAGTGCGGGACTCTCTGAAGAAAGCCCTGATGATGAGAGGGCTAATCCCAGAATGCTGTGCAGTGTACAGAATACAAGATGGGGAAAAGAAACCAATTGGCTGGGACACCGATATTTCCTGGTTGACTGGGGAGGAGCTGCATGTAGAAGTTTTAGAAAATGTACCACTAACAACGCACAACTTTGTGCGGAAGACCTTCTTCACCCTAGCCTTCTGTGACTTTTGCCGGAAGCTCCTATTCCAGGGTTTCCGCTGTCAGACATGTGGGTACAAGTTCCACCAGCGCTGCAGCACAGAAGTGCCTCTCATGTGTGTCAACTACGACCAGCTGGACTTACTGCTGGTATCCAAGTTTTTTGAGCACCACCCCATCACACAGGAAGAGATGTCCTCTGAGGGGACCACCCCGGTGTGTGAAGTCAGCCCTTTCATCCCTCCCTCCACCTCCAGCGGGTCTCTCTGCCACCCCAATGCCTCCCCTTCGAAGTCCATCCCCATTCCTCAGAATTACCGCCCTGGGGATGAAGACCACCGAAACCAGTTTGGCCAGAGAGACCGCTCTTCCTCTGCTCCCAATGACTTAATTAGAGATCAAGGCTTGCAGAGATCAGATGGAGcccCCTTGACCCAACCAGCTCGCTGCTTGAGGAAGTTTCGAACCCGGACCTCAAGCCCCCTCCTATACTCCTACCCCAATGAcattgtgtttgattttgagCCTGGTCCCGTGTTTCGAGGTAGCTAG

Function

symbol description
braf Predicted to enable protein kinase activity. Predicted to act upstream of or within intracellular signal transduction and protein phosphorylation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 7; carcinoma (multiple); cardiofaciocutaneous syndrome (multiple); central nervous system benign neoplasm (multiple); and melanoma (multiple). Orthologous to human BRAF (B-Raf proto-oncogene, serine/threonine kinase).

NR:

description
PREDICTED: serine/threonine-protein kinase B-raf

GO:

id name namespace
GO:0035556 intracellular signal transduction biological_process
GO:0006468 protein phosphorylation biological_process
GO:0005057 obsolete signal transducer activity, downstream of receptor molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00006643 True 1335 mRNA 0.56 10 12859177 12872555

Neighbor

gene id symbol gene type direction distance location
AMCG00006644 NA coding downstream 7393 12849007 ~ 12851784 (-)
AMCG00006642 LOC103363517,LOC104927640,LOC108425352 coding downstream 57276 12766012 ~ 12801901 (-)
AMCG00006637 arhgap8 coding downstream 297741 12547795 ~ 12561436 (-)
AMCG00006634 nup50,LOC107687567,LOC107601009 coding downstream 414327 12433023 ~ 12444850 (-)
AMCG00006633 NA coding downstream 466476 12386912 ~ 12392701 (-)
AMCG00006647 NA coding upstream 88614 12961169 ~ 12987800 (-)
AMCG00006649 NA coding upstream 118248 12990803 ~ 12991381 (-)
AMCG00006648 NA coding upstream 125894 12998449 ~ 13024022 (-)
AMCG00006651 NA coding upstream 168545 13041100 ~ 13049320 (-)
AMCG00006652 rergl,rergla,LOC107560713,LOC107757225,LOC107594299 coding upstream 184333 13056888 ~ 13061928 (-)
G111158 NA non-coding downstream 98341 12759571 ~ 12760836 (-)
G110957 NA non-coding downstream 957009 11899963 ~ 11902168 (-)
G110942 NA non-coding downstream 1062835 11794536 ~ 11796342 (-)
G110940 NA non-coding downstream 1065676 11790052 ~ 11793501 (-)
G110939 NA non-coding downstream 1069943 11788940 ~ 11789234 (-)
G111182 NA non-coding upstream 82055 12954610 ~ 12959628 (-)
G111389 NA non-coding upstream 1131198 14003753 ~ 14004141 (-)
G111421 NA non-coding upstream 1263773 14136328 ~ 14137746 (-)
G111448 rap1b,LOC106576640,LOC107695907 non-coding upstream 1295576 14168131 ~ 14214816 (-)
G111451 NA non-coding upstream 1310226 14182781 ~ 14299856 (-)
AMCG00006625 c4h11orf98,c8h11orf98,cunh11orf98,c19h11orf98 other downstream 718772 12137182 ~ 12140405 (-)
AMCG00006622 lrp6 other downstream 728794 12071390 ~ 12130383 (-)
AMCG00006621 borcs5 other downstream 789517 12049494 ~ 12069660 (-)
AMCG00006618 crebl2,LOC102781596 other downstream 834628 12017869 ~ 12024549 (-)
AMCG00006579 yaf2,LOC108439407,LOC105018284,LOC106573089,LOC106561625 other downstream 2751892 10087275 ~ 10107285 (-)
AMCG00006641 mrps33,LOC106591474 other upstream 3737 12876292 ~ 12878656 (-)
AMCG00006663 hmga2 other upstream 582877 13455432 ~ 13503228 (-)
G111489 NA other upstream 1487673 14360228 ~ 14364422 (-)
G111621 NA other upstream 1839462 14712017 ~ 14753970 (-)
G111767 LOC107575789 other upstream 2880266 15752821 ~ 15753235 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_028587 braf coding NC_007115.7 CM002888.2 12074776 ~ 12102036 (-)
grasscarp (Ctenopharyngodon idella) CI01000020_05269653_05286461 BRAF coding CI01000020 null 5269653 ~ 5287374 (+)