six1a (six1a,six1,LOC107588725,LOC107675533,LOC107708210,LOC107668775,LOC108434988)


Basic Information

Item Value
gene id six1a
gene name six1a,six1,LOC107588725,LOC107675533,LOC107708210,LOC107668775,LOC108434988
gene type misc
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056711.1
NCBI id CM032080.1
chromosome length 25085836
location 11643930 ~ 11648035 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>TU137742
GGatcatttaataattgattaGTAGGCTATCAACTGCAGTGTGAGTGAGtatgtgcgtgagtgtgtgtgtgtgtgtgtgttcaaggtCTCCAGTTTCAGGCCTTGACGTCCGCCCTCCGGGGAGGAAACGGAACGGATCTGTAGATGCAGTTCTGCTCTGCTGGCCGGTTTCAGAACAGACCGGGGCGCGCTAATCACGGAATGACGCTGCGCTGGGTTTCTCAGTCATACAGTACAATCCGCACCCGAATCTCACGTGTGCAACCCCGACGGGTGACAGCGGTGCCACACAACCGGACAGCAGGCTGTTATCGAAATTGGAGCATCAAGAGATAAACGTGGAGCAGGTCGCGTGCGTCTGCGAGGTGCTGCAGCAGGGTGGAAACCTGGAGAGGCTCGGACGTTTCCTTTGGTCCCTGCCGGCCTGCGACCACCTCCACAAGAACGAATCCGTGCTGAAAGCGAAGGCCGTGGTGGCCTTCCACCGGGGGAACTTCCGCGAGCTCTACAAGATCCTGGAGAGCCACCAGTTCTCCGCGCACAACCACCCGAAGCTGCAGCAGCTGTGGCTGAAGGCGCACTACGTGGAGGCGGAAAAGTTACGGGGCCGCCCGCTAGGCGCTGTGGGCAAATACCGCGTGCGCAGGAAATTTCCTTTGCCCCGTACGATCTGGGACGGCGAGGAGACTAGCTACTGCTTCAAGGAGAAGTCTCGGGGCGTGCTGCGTGAATGGTACACGCACAACCCCTATCCGTCTCCGCGGGAGAAGCGGGAGCTGGCGGAGGCAACGGGACTGACCACCACACAGGTCAGCAACTGGTTTAAAAACAGGAGGCAGAGAGACCGGGCAGCTGAGGCTAAAGAGAGAGAAAACAGCGAGAACAACGGCGTTGGAGGTAAGCAGAGCCAGCGGTCTCCGCTCGACGGAGTCAAGTCGCTCATGTCCAGCTCAGAGGATGAGTTCTCTCCGCCGCAGAGCCCCGAGCACAGCTCCGTGCTTCTGCTGCAGGGAAACATGAACAATCCCGGGGCTCCCGCGTACCCAATGCCCGGCCTCGGTGCGCAGCACTCGGTGCACAGCATGCAAGGACATCCGCATCAGATCCAGGATTCACTGTTGGGATCTCTAACATCCAGCCTTGTGGATTTAGGATCTTAGGACGTCTCGTTCGTAATTTAAGCGACAAGACTTAAAACCATAAATAACCAATATTTACGGCGTTACCGTATATTCTCATGACGCACAGGACGTTTGCTAAAATAAACTACTCTTTTGCAAACGATTGGGAAAATGGGAGAAAATCAAAAAAGTTTCTCTGAGTTTTGGGAATTTTAAGTATACTGGACAAGTGcgtaaaatttgtaaaaaaaaaaacagtaaggcCAATATTTAAGGAAATTCGCAGTACTGTTGGATACATAAACCTTTAATAATTTATGATGTTTTACTCAAAGATTAATTTATAGAAATTGTTCTGTATTGGACAGTACGAATAGCAGGGATTTTAATGAGAAATCATTGGCTTCGGACATCTTAAACTAAACTCTGTGGATGTGGAAACTTTGtttcgttctttttttatttagtttaaatataacACTACGTTGTATTTGTAGTTTTGAAAACAGAGGctctccaatttttttttatttttttttttatatcacacaTCGTCCACGTTTTAAGTCAAGTCAACGTTTTGAGCATTTGTCTTTGACTCGGAAAAGC
>XM_043254698.1
CCGCCCTCCGGGGAGGAAACGGAACGGATCTGTAGATGCAGTTCTGCTCTGCTGGCCGGTTTCAGAACAGACCGGGGCGCGCTAATCACGGAATGACGCTGCGCTGGGTTTCTCAGTCATACAGTACAATCCGCACCCGAATCTCACGTGTGCAACCCCGACGGGTGACAGCGGTGCCACACAACCGGACAGCAGGCTGTTATCGAAATTGGAGCATCAAGAGATAAACGTGGCACGGGGATTTTTGCCTGAGAAGCCATTTGAGAGGAATACACACAGAGCCTCGGGATAGGAGGTTACTGCGTGGTGGATTGCACCGGGCCGCGATGTCAATCTTGCCCTCTTTCGGTTTTACGCAGGAGCAGGTCGCGTGCGTCTGCGAGGTGCTGCAGCAGGGTGGAAACCTGGAGAGGCTCGGACGTTTCCTTTGGTCCCTGCCGGCCTGCGACCACCTCCACAAGAACGAATCCGTGCTGAAAGCGAAGGCCGTGGTGGCCTTCCACCGGGGGAACTTCCGCGAGCTCTACAAGATCCTGGAGAGCCACCAGTTCTCCGCGCACAACCACCCGAAGCTGCAGCAGCTGTGGCTGAAGGCGCACTACGTGGAGGCGGAAAAGTTACGGGGCCGCCCGCTAGGCGCTGTGGGCAAATACCGCGTGCGCAGGAAATTTCCTTTGCCCCGTACGATCTGGGACGGCGAGGAGACTAGCTACTGCTTCAAGGAGAAGTCTCGGGGCGTGCTGCGTGAATGGTACACGCACAACCCCTATCCGTCTCCGCGGGAGAAGCGGGAGCTGGCGGAGGCAACGGGACTGACCACCACACAGGTCAGCAACTGGTTTAAAAACAGGAGGCAGAGAGACCGGGCAGCTGAGGCTAAAGAGAGAGAAAACAGCGAGAACAACGGCGTTGGAGGTAAGCAGAGCCAGCGGTCTCCGCTCGACGGAGTCAAGTCGCTCATGTCCAGCTCAGAGGATGAGTTCTCTCCGCCGCAGAGCCCCGAGCACAGCTCCGTGCTTCTGCTGCAGGGAAACATGAACAATCCCGGGGCTCCCGCGTACCCAATGCCCGGCCTCGGTGCGCAGCACTCGGTGCACAGCATGCAAGGACATCCGCATCAGATCCAGGATTCACTGTTGGGATCTCTAACATCCAGCCTTGTGGATTTAGGATCTTAGGACGTCTCGTTCGTAATTTAAGCGACAAGACTTAAAACCATAAATAACCAATATTTACGGCGTTACCGTATATTCTCATGACGCACAGGACGTTTGCTAAAATAAACTACTCTTTTGCAAACGATTGGGAAAATGGGAGAAAATCAAAAAAGTTTCTCTGAGTTTTGGGAATTTTAAGTATACTGGACAAGTGcgtaaaatttgtaaaaaaaaaaacagtaaggcCAATATTTAAGGAAATTCGCAGTACTGTTGGATACATAAACCTTTAATAATTTATGATGTTTTACTCAAAGATTAATTTATAGAAATTGTTCTGTATTGGACAGTACGAATAGCAGGGATTTTAATGAGAAATCATTGGCTTCGGACATCTTAAACTAAACTCTGTGGATGTGGAAACTTTGtttcgttctttttttatttagtttaaatataacACTACGTTGTATTTGTAGTTTTGAAAACAGAGGctctccaatttttttttatttttttttttatatcacacaTCGTCCACGTTTTAAGTCAAGTCAACGTTTTGAGCATTTGTCTTTGACTCGGAAAAGCctgttaatcaaaataaagaaaatcaggagactacaataaataaacacgaaggctcaaaataataaaaatatgtcaatCCACGTGACACATCCAAGCCGGAAGAGGGCATGAGCGCGTGAAAAATGAGAACGACAGAAACATCAACAAGAAAAATTGGCCCTTTTgcagagaggacagagagacgCCAAGAGGCGCCAGGCTGACTCTTTGACCGTTATTCaggaaaactaaaattaaaaaaggtaacaaaaaaaaaacaacaacaaacaaaaaagaaacacggGCACACTGAGTCACTTTAAGCTTTGTAACATTACGTTTTCTAAACATTTCTTAGTTCATTacgctttaataaaaaaaaaacagaatggaGACAGAGGGAGAAAAAGGGAGTATTGctcatttttctgtttgttctgtCAGTTCTGGGCCACTGGAAACTGACACGACACGCAAGAGAAGCTCTAAAGACCCTCCACCCAAAACAAAAACCTCTACAAAACAATTGAAACGATAGTGAGCTTAATCgtctttttttagtaaaaaaaaaaaaaaaaaaaaaaacaaatggaaaaactAAAGATTAAAAATCGAATTTGTCGCGCgtttgttgacatttttaacCGCGAGGAAGGAATCGGACGATacgaaaaacaacatttctggaaCAATGCGCAATGTGAATTATTCTGTGTCTTTTTACGTCGATAGTCTCGTGTCAGTGTAAATGGTTTTGAGCAGAGAGCGCAGAGGGTTTCCGGGCCCTAATTAAAACCATTCTCCGGGTTTAGAGGGGCTTGATTGCAGGAATGAGGAGGGACACCCTACCAGCCTCGAGCCACGGGGTGTTGCACAAcagaaatctatctatctatctatctatctatctatctatctatctatctatctatctatctatctatctatctgtctatctgtctgtctatctagatttaaaaacattcaatattcattgtcacttttgacaaaacataaacaggaaatattctaaatatttttcatattggGAATAAATATCTTCTCGAGACTTAAACTGAGGAACCCAGAATTCTTCCACCAATAAGGCCAATGCTGGGCATGAATGTCAGCTGCGGTTTTAATCAACAGTCtaattatattttgcacataTAAACATTCCTTACATCTGCTATGCTCATATTGGTGGAAATTGAgaaatccaaataaaaaaaaaaaaaggtttcttttcatttctgtgcTGGTGATGTGGCCCACTCTGTTTTCCCCGACCGATTCGACGACATAGTTTGATAACTgagtaaaagtttaaaatagctATGAAtcagacttttcatttttcgTGATAATCCAACCCCAGACAAAGTGTCATCATCAAATGCCTTTTTGTTTATGCTTTCACCCTGGACTTTCTTTAGGGACCACAATTTACACAGTAAATCTGAAACGATCGGTTAATGTC

Function

symbol description
six1a Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within regulation of inner ear receptor cell differentiation; regulation of skeletal muscle cell proliferation; and skeletal muscle fiber development. Predicted to be located in cytoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in musculature system; nervous system; otic vesicle; and somite. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 23; branchiootorenal syndrome; and nephroblastoma. Orthologous to human SIX1 (SIX homeobox 1).
six1 Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and protein localization to nucleus. Located in nucleolus and nucleoplasm. Implicated in autosomal dominant nonsyndromic deafness 23; branchiootorenal syndrome; and nephroblastoma. Biomarker of breast cancer; hepatocellular carcinoma; nephroblastoma; neurilemmoma; and ovarian carcinoma.

NR:

description
sine oculis homeobox like 1

GO:

id name namespace
GO:0051146 striated muscle cell differentiation biological_process
GO:0043282 pharyngeal muscle development biological_process
GO:0006915 apoptotic process biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:2000980 regulation of inner ear receptor cell differentiation biological_process
GO:0002074 extraocular skeletal muscle development biological_process
GO:0021984 adenohypophysis development biological_process
GO:0048935 peripheral nervous system neuron development biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0000976 transcription regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG:

id description
K15614 SIX1; homeobox protein SIX1

RNA

RNA id representative length rna type GC content exon number start site end site
TU137742 False 1730 lncRNA 0.50 3 11645389 11648035
XM_043254698.1 True 3207 mRNA 0.44 2 11643930 11647926

Neighbor

gene id symbol gene type direction distance location
dhrs7 dhrs7,LOC107588602,LOC107548599,LOC107588604 coding downstream 37667 11602620 ~ 11606263 (-)
rtn1a rtn1a,LOC107668786,LOC107707153,LOC107588606,LOC107757140,LOC107548601,LOC107673903 coding downstream 66580 11557359 ~ 11577350 (-)
pgam1a pgam1,pgam1a,LOC107668811,LOC107548630,LOC107707176,LOC107673951,LOC107700858,LOC103038634 coding downstream 103827 11533450 ~ 11540103 (-)
ubtd1a ubtd1a,ubtd1,LOC107708242,LOC107673956,LOC103038242,LOC107548628 coding downstream 118670 11520086 ~ 11525260 (-)
rrp12 rrp12,LOC103399548 coding downstream 124595 11509238 ~ 11519335 (-)
six4a LOC107668780,LOC107708200,LOC107588724,LOC107757135,LOC107675560,LOC107548598 coding upstream 6355 11654390 ~ 11661586 (-)
trmt5 trmt5,LOC107707083,LOC107668822,LOC107588721,LOC107757133 coding upstream 30582 11678617 ~ 11681317 (-)
LOC122356134 NA coding upstream 80488 11728523 ~ 11733236 (-)
sertad4 sertad4,LOC107707050,LOC107668837,LOC107588595,LOC107548617,LOC107757095 coding upstream 91360 11739395 ~ 11750014 (-)
syt14a syt14a,syt14,LOC107548616,LOC107577703,LOC107675522,LOC107707984,LOC107668771,LOC107757094 coding upstream 107561 11755596 ~ 11788142 (-)
G93063 NA non-coding downstream 14181 11629440 ~ 11629749 (-)
G93062 NA non-coding downstream 18790 11624798 ~ 11625140 (-)
G92935 NA non-coding downstream 230677 11412183 ~ 11413253 (-)
G92934 arhgap22,LOC107588697,LOC107668831,LOC107708000,LOC107673870,LOC107548604 non-coding downstream 232491 11410630 ~ 11411439 (-)
G92842 NA non-coding downstream 381293 11257080 ~ 11262637 (-)
G93099 NA non-coding upstream 89982 11738017 ~ 11738231 (-)
G93111 NA non-coding upstream 153980 11802015 ~ 11802286 (-)
LOC122356216 NA non-coding upstream 256733 11904768 ~ 11938181 (-)
LOC122357025 LOC107585516,LOC108412594,LOC105899417 non-coding upstream 335676 11983711 ~ 12029622 (-)
G93144 NA non-coding upstream 388577 12036612 ~ 12036818 (-)
zdhhc16a zdhhc16,zdhhc16a,LOC107708229,LOC107668773,LOC107673955,LOC107548628 other downstream 111473 11525403 ~ 11532457 (-)
rassf4a LOC107668802,LOC107588618,LOC107707254,LOC107564351,LOC107673909,LOC107757153 other downstream 424945 11200552 ~ 11218985 (-)
G92819 NA other downstream 708599 10924944 ~ 10935331 (-)
c13h10orf53 zgc:153142,LOC107683743,LOC107588649,LOC107707510,LOC107716306,LOC107673897 other downstream 1009364 10632250 ~ 10634566 (-)
LOC122356841 fancl,LOC107585345,LOC107718841 other downstream 1452164 10174413 ~ 10191766 (-)
utp25 diexf,LOC107668835,LOC107707040,LOC107675582,LOC107757128 other upstream 123393 11771428 ~ 11799032 (-)
vti1b vti1b,LOC107655020,LOC107705385,LOC107724223,LOC107675543 other upstream 630419 12278454 ~ 12293594 (-)
tmem234 tmem234,LOC107675523,LOC107576456 other upstream 781162 12429197 ~ 12430778 (-)
LOC122356414 NA other upstream 909042 12557077 ~ 12597302 (-)
LOC122356823 LOC107654911,LOC107705409,LOC107600568,LOC107683712 other upstream 1661917 13309952 ~ 13325051 (-)

Expression


Co-expression Network