LOC103021456 (ptch2,LOC107557169,LOC107700991,LOC107720855,LOC107599897,LOC107722076)


Basic Information

Item Value
gene id LOC103021456
gene name ptch2,LOC107557169,LOC107700991,LOC107720855,LOC107599897,LOC107722076
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035912.1
NCBI id CM008315.1
chromosome length 41032606
location 95083 ~ 123672 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007235356.3
CGGAGCAGCGCGAGACACACGGTGCCAGCACGGGCACGGGAATACACCGCCGCCCCGCTCTACACAcgactcaacacacacacacaccgtacacacacgcgcgcgcacactCTACTCTCTACACGCACTGTGCACTGCGCGCGGACAGGACCGAGACCGGGCGGATGAAGAGCGGTGGGCGCGCGCAGACCGGGGCGCATGATGTTGGGATGGTGCCGCTGGATTTCGGCTCgcggacagcagcagcaggagaagAGTGAAGCGCGCGCTCCCAGCTCCCCGTCTCCCCGCGTGGACTATGGCCGCGGAGCCGCGAGACCCTCCCCCGGACTACGAGCGCGCGCCTCCGTCTAACGACCCACGGCAGCCCCGCGCGGACACCCGCCGCCACGCCGCGCTCGCACTCAACCACTTCAACAAGGGGAAAGCTGCGGGGCAGAGAGCGCCGGTGTGGATCCGGGCCAGGTTCCAGGCTCTGCTCTTTACTCTGGGTTGCCATATCCAGCGACACTGCGGAAAAGTACTGTTCATTGGGCTGCTGGTGTTCGGCGCTCTATCGGTCGGACTGCGAGTCGCCGCCATCGAGACGGATATCGAGCAGCTGTGGGTGGAAGccGGCAGTCGAGTGAGTCGGGAGCTGAGATATACGAAGGAGAAGCAGGGCGAGGAGACGGTGTTCACCTCTCAGATGCTCATTCAGACGCCCAAACAGGAAGGAACCAATATTCTTACCCAGGAGGCTTTGCTGCTCCACCTGGAGGCGGCGCTGTCGGCCAGTAAAGTCCAGGTGTCTCTTTATGGAAAATCCTGGGACCTCAACAAAATCTGCTTCAAGTCTGGAGTCCCTATTATCGAGAACGTCATGATCGAAAGGATGATCGATAAGCTTTTCCCCTGTATGATCGTCACTCCGCTGGACTGTTTCTGGGAGGGATCTAAACTGCAGGGAGGATCTGCGTATTTACCGGGGATGCCTGATATTCAGTGGATGAATCTGGACCCTCTGAAGCTGATGGAGCAGCTGAGCCAGTTCACCTCTCTGGAGGGCTTCAGGGAGATGCTGGATAAAGCTCAGGTGGGCCACGCCTACATGAACCGACCCTGTCTGGACCCGAACGACCCAGACTGCCCCCACAGCGCCCCCAACAAAGACCTGCGGCAGagTCCTGAAATCGCTGAGGAGCTGCAGGGCGGCTGCAGCGGCTTCTCTAAGAAGTTCATGCACTGGCAGGAAGAGCTGATCCTGGGAGAACGAGCAAAAAACTCACAGGGATCTTTACAAAGCGCTGAGGCCCTGCAGACCATGTTTCTCCTCATGAGCCCGAAGCAGCTGTACGAACACTTTAAAGACGACTACGAGATCCACGACATCAACTGGAACGAGGACAAGGCCACCGCCATCCTGGAGTCCTGGCAGAGGAAGTTTGTGGAGGTGGTCCACAGCAGCATTCCTCAGAACTCCTCCTCCAACGTCTACgccttctccaccaccaccctcaACGACATCATGAAGTCTTTCTCTGACGTCAGCGTCATCAGGGTGGCCGGCGGTTACCTGCTCATGctggCGTACGCCTGTGTTACGATGCTGCGCTGGGACTGTGCTAAGAGTCAGGGTGCGGTTGGTCTGGCCGGGGTCCTGCTGGTGGCGCTCTCCGTTGCTGCCGGTTTGGGACTGTGTTCTCTTCTCGGGCTTTCTTTCAATGCTGCCAccacacagGTGCTGCCGTTCCTGGCGTTGGGGATCGGGGTGGACGACATGTTTCTTCTGGCTCATTCCTTCACCCAGGCCGGATCCAACATCCCCTTCAAGgagaggACTGGTGACTGTTTGAGGAGAACCGGCACCAGCGTGGCTCTCACCTCCATTAACAACATGATTGCCTTTTTCATGGCGGCACTGGTGCCCATTCCCGCCCTGAGGGCGTTCTCTCTGCAGgctgCTGTCGTGGTGGTGTTTAATTTTGCAATGGTTCTGCTCATCTTCCCTGCCATCCTCAGTCTGGACTTGCACAGGCGTGAGGACAAAAGGCTGGACATTCTGTGCTGCTTTTACAGCCCCTGCTCCTCTCGAGTGATCCAGATCCAGCCTCAGGAGTTCTCCGACTCTAATGACAACCACCCACCGCCTCGCTCCCACGCCCCGGCCACGCCCACCTTCCCCGtctccaccaccatcaccaccagcaCGCACATCACCACCACGGTGCAGGCCTTCACGCAGTGCGACGCTGCCGGCCAGCACATCGTCACCATCCTGCCCCCGACCTCACAGATCTCCACCAGCCCTGGACCCCCGCCCCCCTCATCCACCTCCTCCACCGACCCGTATGGCTCGCGCCTCTTCACCCCCTCCAGCTCCACCCGGGACCTGTTGTCACAGGCCGAGGAGTCCCGCTCGTCCGAGTGCGCCCCCCTGCCCTTCCTTCACTGGGACCTGGCTCGCTTCGCCCGGAACAGGTACGCCCCCCTGCTGCTGAAGCCTGAGACTAAGACGGCAGTAGTGGTGGCGTTCGTGGCTCTGCTTGGCCTCAGCCTCTACGGCACCACCATGGTCCGCGACGGGCTCTACCTAACGGACATAGTGCCCCGAGACACAAAGGAGTACGATTTTATCTCAGCGCAGTTTAAATACTTCTCCTTCTACAACATGTACTTGGTCACTATGGACGGCTTCGACTATGCGCGCTCCCAGCGGGAACTGCTGCAGCTCCACAATGCCTTCAACTCCGTCAAGTACGTGGTGAGGGACAGCGATCAGAAGCTGCCGCGCATGTGGCTCCACTACTTCCAGGACTGGCTGCGAGGACTTCAGGTATCTTTTGATGCTGACTGGGAATCAGGCAGGATCACCCCTGACAGCTTCCGCAACGGCACCGAGGACGGAGCTCTAGCCTACAAACTGCTCATTCAGACCGGCTCCAAGAAAGAGCTCTTCAACTACAGCCAGCTGACGTCCCGGCGCCTGGTGGACGATGATGGCATGATCCCTCCCGAGGTCTTCTACATCTATCTGACCGTGTGGGTCAGTAACGACCCGCTGGGTTACGCCGCCTCTCAGGCTAACTTCTACCCCCACCCTCACGAGTGGATTCACGACAAGTACGACACCACAGGCGAGAATCTGCGAATTCCTGCCGCTGAGCCTTTGGAATTTGCCCAGTTCCCCTTCTACCTAAACGGTCTCCGCCAAGCGTCTGACTTCATCGAGGCCATTGAGAGCGTTCGCTCCGTTTGCGAGGAGTTCATGCGCAAGGGCATCCAGAACTACCCTAACGGCTACCCGTTTCTCTTCTGGGAACAGTACATCGGCCTGCGCCACTGGTTCCTGCTGTCCATCAGCGTGGTGCTCGCCTGCACCTTCTTGGTGTGCGCCGTCCTGCTGCTCAATCCGTGGACTGCAGGCATCATAGTTTTTATCTTGGCGATGATGACAGTAGAGTTGTTTGGCATCATGGGACTTATTGGTATCAAGCTGAGTGCCATCCCTGTGGTTATCCTTATTGCCTCTGTTGGAATTGGAGTGGAGTTCACAGTACACGTTGCACTGGGTTTCTTGACCGCCATTGGGGACAGGAACACGCGTTCCGTTGCGGCTCTGGAGCACATGTTTGCTCCGGTGATGGACGGCGCTATTTCCACTTTTCTTGGGGTGCTCATGCTTGCCGGGTCCGAGTTTGACTTCATTATGAGgtacttttttgcaGTTCTGGCCATCCTGACCTTGTTGGGAATCCTGAACGGCTTGGTGCTGCTGCCGGTTCTCCTGTCTATCATGGGTCCTCCAGCAGAGGGCAGCAATGGCAGCGACGGCAACTGCCTGTCCAGCTCCTCACCCGAGCTCACGCCTCCAACAATGAACCACCACGGATACTACGCAGGACACGTCCCCAGAGGACGACGGCAGGCCTTTACTGAGGTCTCGGATTCTGAGTACTACTCTGAGACAACCACCTCATCTGGGATTGGGGAAGAAGACCACAAGCACTACGACAGGAGCGCATACATAACtccacccccccaaccccccaccTCCCACATCCTGCTGGAGGCCAGCAAGAACCCTACATTTCCTAAACTTACAGTAGTGAAACCGTTCAGCGAAAGGTCGGCCGCAGGTTGTCAGATGGATCAAGCCGGCGAGTCGATGCAGAACGCAGTGAACTCCATTAGTTCACAGATCACGCGGTGGGACGGCAAGCAAGAGTACCAAGGGTCAAGGACTCAGTATTTACCCAGCGATAGGACCCACTGTCCTGGGAGGACTACTCACTGTGGCCCCAGTAGAGGGCCACAGCAGAACAGGACTACAGCGCCGGGCCATGCCGCCAACACGGTCACTATGGTCACGGCCACCGCCTCGGTGACGGTGGCGGTTCACCCCAGTCTGCCGGGGTCCTATCAGGGTTACATGCACGAGGGCTTTGAGGACAGCGAGTCGGACTCTTTCAAGGACATTAAGAGGACTTCCCGAACTTACGCTGCTCAGTCGTCCCACAGAGACTCTTTGGAAATTCATGATTTGGAATCGCTAGAAAAGAACCAGCATCAAGCTAACCAGGGTCTAGGTGGTTCACGGATTCAAGCCGCCAAAGATTGCTAGACTCCCTCATACCCTCGTCTGGAATCTGTCTCTGGATGTTTTGAGACATTCACAGCCGACCCTGTGTCTCCGAACTGTACATAGACCTCACAGATGAgaggatttattttaaaagatattaaaaatgttgttttaagattatatatacatttataaatatatattttaatactaaaaagagggaaaattatttaaaagagTACTGTATAACTTGTTTTCTCTTATGTAAAGTCAGAGGTATACGAGGAATCGGAGGCTTTTATTCCTCCTTTGTATAGATTAAGAAATGttctatatgtaaaaaatatcagATGTGAAATGGTATTAggttattaaaaatgaaaggtca

Function

symbol description
ptch2 Predicted to enable hedgehog family protein binding activity; hedgehog receptor activity; and smoothened binding activity. Acts upstream of or within several processes, including cardioblast differentiation; negative regulation of smoothened signaling pathway; and retinal ganglion cell axon guidance. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; digestive system; head; mesoderm; and musculature system. Used to study coloboma. Human ortholog(s) of this gene implicated in basal cell carcinoma; medulloblastoma; and nevoid basal cell carcinoma syndrome. Orthologous to human PTCH2 (patched 2).

NR:

description
PREDICTED: protein patched homolog 2

GO:

id name namespace
GO:0007224 smoothened signaling pathway biological_process
GO:0043010 camera-type eye development biological_process
GO:0031290 retinal ganglion cell axon guidance biological_process
GO:0009954 proximal/distal pattern formation biological_process
GO:0048635 negative regulation of muscle organ development biological_process
GO:0010002 cardioblast differentiation biological_process
GO:0001649 osteoblast differentiation biological_process
GO:0016021 integral component of membrane cellular_component
GO:0008158 hedgehog receptor activity molecular_function

KEGG:

id description
K11101 PTCH2; patched 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007235356.3 True 4952 mRNA 0.56 24 95083 123672

Neighbor

gene id symbol gene type direction distance location
LOC111194215 NA coding downstream 5553 88370 ~ 89530 (-)
eif2b3 eif2b3,ei2bg,LOC107720854,LOC107700990,LOC107722074,LOC107599900 coding upstream 3413 127085 ~ 146205 (-)
cenpl cenpl coding upstream 49569 173241 ~ 176666 (-)
brinp2 brinp2,LOC107720848,LOC107658350,LOC107700985,LOC107562711,LOC107722070 coding upstream 162678 286350 ~ 423788 (-)
pappa2 NA coding upstream 594351 718023 ~ 750580 (-)
tnn NA coding upstream 868221 991893 ~ 1026466 (-)
G137611 NA non-coding downstream 16720 75676 ~ 78363 (-)
G137610 NA non-coding downstream 25338 68959 ~ 69745 (-)
G137646 NA non-coding upstream 9486 133158 ~ 134296 (-)
G137648 klhl20,LOC102300935 non-coding upstream 38024 161696 ~ 163945 (-)
G137659 NA non-coding upstream 69682 193354 ~ 193998 (-)
G137710 NA non-coding upstream 157444 281116 ~ 386357 (-)
G137719 NA non-coding upstream 295089 418761 ~ 420399 (-)
LOC111194217 pappa2,LOC107722077,LOC107678935,LOC107726923,LOC107658303,LOC107558342 other upstream 572231 695903 ~ 717323 (-)
G138199 plk3,LOC107563563,LOC107722069,LOC107658359,LOC107726922,LOC107557223 other upstream 926860 1050532 ~ 1101493 (-)
LOC103042176 zgc:55943,c7h1orf21,LOC103042176,LOC108430752,LOC107709356,LOC107671715,LOC107559369,LOC107593773,LOC107727521 other upstream 2354023 2477695 ~ 2486894 (-)
LOC103045355 LOC108430731 other upstream 2926728 3050400 ~ 3062759 (-)
LOC103025790 NA other upstream 2971929 3095601 ~ 3114686 (-)

Expression


Co-expression Network