Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_007596 |
| gene name | fgf2 |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007125.7 |
| NCBI id | CM002898.2 |
| chromosome length | 52660232 |
| location | 567216 ~ 572742 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| fgf2 | Predicted to enable fibroblast growth factor receptor binding activity and growth factor activity. Acts upstream of or within Kupffer's vesicle development. Predicted to be located in extracellular region. Predicted to be active in cytoplasm; extracellular space; and nucleus. Is expressed in brain; eye; forerunner cell group; and kidney. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; corneal neovascularization; diabetic neuropathy; gastric ulcer; and impotence. Orthologous to human FGF2 (fibroblast growth factor 2). |
| id | name | namespace |
|---|---|---|
| GO:0010628 | positive regulation of gene expression | biological_process |
| GO:0030154 | cell differentiation | biological_process |
| GO:0009887 | animal organ morphogenesis | biological_process |
| GO:0050679 | positive regulation of epithelial cell proliferation | biological_process |
| GO:0043406 | positive regulation of MAP kinase activity | biological_process |
| GO:0008543 | fibroblast growth factor receptor signaling pathway | biological_process |
| GO:0008284 | positive regulation of cell population proliferation | biological_process |
| GO:0070121 | Kupffer's vesicle development | biological_process |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | biological_process |
| GO:0030324 | lung development | biological_process |
| GO:0001934 | positive regulation of protein phosphorylation | biological_process |
| GO:0030334 | regulation of cell migration | biological_process |
| GO:0010595 | positive regulation of endothelial cell migration | biological_process |
| GO:0042060 | wound healing | biological_process |
| GO:0005576 | extracellular region | cellular_component |
| GO:0005615 | extracellular space | cellular_component |
| GO:0005634 | nucleus | cellular_component |
| GO:0005737 | cytoplasm | cellular_component |
| GO:0005104 | fibroblast growth factor receptor binding | molecular_function |
| GO:0008083 | growth factor activity | molecular_function |
| id | description |
|---|---|
| ko04010 | MAPK signaling pathway |
| ko04014 | Ras signaling pathway |
| ko04015 | Rap1 signaling pathway |
| ko04020 | Calcium signaling pathway |
| ko04151 | PI3K-Akt signaling pathway |
| ko04550 | Signaling pathways regulating pluripotency of stem cells |
| ko04810 | Regulation of actin cytoskeleton |
| ko05200 | Pathways in cancer |
| ko05205 | Proteoglycans in cancer |
| ko05207 | Chemical carcinogenesis - receptor activation |
| ko05226 | Gastric cancer |
| ko05218 | Melanoma |
| ko05224 | Breast cancer |
| ko05167 | Kaposi sarcoma-associated herpesvirus infection |
| ko01521 | EGFR tyrosine kinase inhibitor resistance |
| ko04052 | Cytokines and growth factors |
| ko00536 | Glycosaminoglycan binding proteins |
| id | description |
|---|---|
| ZDB-GENE-040318-1 | Predicted to enable fibroblast growth factor receptor binding activity and growth factor activity. Acts upstream of or within Kupffer's vesicle development. Predicted to be located in extracellular region. Predicted to be active in cytoplasm; extracellular space; and nucleus. Is expressed in brain; eye; forerunner cell group; and kidney. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; corneal neovascularization; diabetic neuropathy; gastric ulcer; and impotence. Orthologous to human FGF2 (fibroblast growth factor 2). |
| ensembl_id | ENSDARG00000104348 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00014898 | True | 926 | mRNA | 0.52 | 3 | 567216 | 572742 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_007595 | CABZ01085878.1 | coding | downstream | 15180 | 540157 ~ 552036 (-) |
| XLOC_007594 | NA | coding | downstream | 59085 | 506778 ~ 508131 (-) |
| XLOC_007593 | spry1 | coding | downstream | 68237 | 497695 ~ 498979 (-) |
| XLOC_007592 | zgc:172215 | coding | downstream | 74187 | 484389 ~ 493029 (-) |
| XLOC_007591 | ANKRD50 | coding | downstream | 96711 | 467104 ~ 470505 (-) |
| XLOC_007597 | NA | coding | upstream | 61296 | 634038 ~ 664120 (-) |
| XLOC_007598 | LO018568.1 | coding | upstream | 97240 | 669982 ~ 677801 (-) |
| XLOC_007599 | ube2ka | coding | upstream | 111205 | 683947 ~ 689841 (-) |
| XLOC_007600 | si:zfos-741a10.3 | coding | upstream | 126487 | 699229 ~ 706345 (-) |
| XLOC_007601 | tlr1 | coding | upstream | 159122 | 731864 ~ 736575 (-) |
| XLOC_007639 | CU855896.3 | misc | upstream | 1834203 | 2406945 ~ 2407072 (-) |
| XLOC_007640 | CU855896.2 | misc | upstream | 1834586 | 2407328 ~ 2407431 (-) |
| XLOC_007641 | CU855896.1 | misc | upstream | 1834994 | 2407736 ~ 2407840 (-) |
| XLOC_007604 | CU928046.1 | non-coding | upstream | 290289 | 863031 ~ 899192 (-) |
| XLOC_007605 | NA | non-coding | upstream | 360261 | 933003 ~ 970853 (-) |
| XLOC_007607 | NA | non-coding | upstream | 430306 | 1003048 ~ 1003398 (-) |
| XLOC_007608 | NA | non-coding | upstream | 485602 | 1058344 ~ 1059534 (-) |
