XLOC_009516 (ctsc)


Basic Information

Item Value
gene id XLOC_009516
gene name ctsc
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 43604032 ~ 43625549 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00018677
GAGAAGGACACGTATTTTTTGGTCCTTGCGTCCTGGTTATTGTTGAACCCCGCGTTTATTTCTACTGTTTGTCCTCCGTCTGGCTTGTTGTGAGGATGCGCGCGCTTTccgttattgttttgtttgcgtttatAGCCGGGGCTGCGGCCGATACTCCGGCAAACTGCACATATGAGGACCTGCTGGGCACCTGGATCTTCAGTGTGTCCAATGTGGGTCAGGACAAGACCATCAACTGCTCCAGTACAGGCCAGGCGGTGAGCACGGTGACTGTGGACCTGCAGAAGCTGTCCGTAGCTGTGGATGATCTGGGTCACACAGGCTTTTTCACACTCATCTATAACCAGGGCTTCGAGGTGGTGATCAATGAATACAAATGGTTCGGGTTTTTCAAGTATACTCAGCAGGGCTCAGAGGTGGTGAGTTACTGCGATCAGACGCTGCCCGGTTGGGTTCATGATGTTTTGGGCAGTAACTGGGCCTGTTTCACCGGGAAGAAAGTGCAGCCCATCCCTCCCCGAGTGGACCGTCGTCACATGCTTGGATTTGAGCACAGACTGCTGATGAAGCTGCCGTACACGAACAACATGATGTTTGTGGATGAAATAAACTCCGTTCAAAAGTCTTGGACAGCAACGGTGTACAGTTTTCATGAGACTCTGTCCATACATGAGATGCTGAGAAGATCAGGAGGACCTGCCTCCAGAATTCCACGACGTGTCAGGCCTGTAACTGTTGCTGCGGACAGTAAAGCAGCCGCTGGTCTTCCTCAACACTGGGATTGGAGAAACGTTAATGGAGTCAACTTTGTCAGTCCAGTTCGCAACCAAGCTCAGTGCGGCAGCTGCTACTCTTTCGCCACTATGGGAATGCTGGAGGCACGAGTGCGGATCCAGACCAACAACACTCAGCAGCCGGTGTTCAGTCCGCAGCAGGTGGTGTCCTGCTCGCAGTATTCACAAgGTTGTGATGGAGGCTTTCCCTACCTGATTGGAAAATACATCCAGGATTTCGGCATCGTGGAGGAGGACTGTTTCCCGTACACCGGGTCTGATTCTCCCTGCAACCTGCCTGCAAAGTGCACAAAGTACTACGCCTCAGATTACCACTACGTCGGCGGGTTTTACGGCGGATGCAGCGAGTCTGCCATGATGCTGGAGCTGGTGAAGAACGGCCCCATGGGAGTCGCTCTGGAGGTCTATCCCGATTTCATGAACTATAAAGAGGGAATCTACCATCACACCGGCCTGCGGGACGCCAACAACCCATTCGAGCTGACCAATCACGCTGTGCTGCTGGTGGGTTACGGCCAGTGCCACAAAACTGGAGAGAAGTACTGGATCGTGAAGAACAGCTGGGGAAGCGGATGGGGAGAAAACGGCTTTTTCAGGATCCGTCGTGGAACGGATGAGTGCGCCATCGAGAGCATCGCCGTCGCTGCTACGCCAATCCCCAAACTGTAGAGAGAGAGGGCGTTCAGATGTGATTTTTATACCCATTCTGCTTTTATTTCTGAATGTTTTTATAATGCCACCTCTagattgaagggatagttcaaccaaaaatggaAATTTGCTTACTATTTACttgccctcaagtggttccaaacccatttgagattctttcttctgacATTTCGTCATCGAGAGCATCGCCGTCGCTGCTACACCAATCGCCAAACTGTAGAAAGAGCGTTCAGATGTGATTTTAACCCATTCTGCTTTTATTTCTGAATGTTTTATTATGCCACTTGTGCagcttaaatggatagttcagccCTAAACGAAAATCTACTTAATATTTATTTGCTCTCAAGTGGTTTTAaccctatttgagtttctttcctccaTCTTTTTCAGAATAAAACCTATTGACATTTTTACACTAAGCTACAAAACTCAATACAGTCTTTGATTTCTCAAATGGCCTCTAAATGTCTTTCTGTAGCCATACAATGAGCCACTTTTGGCTTCTTTTTCCAAGCAGAATGTGTGAACTGAAAATCAATAGCCTCGATTTGATCCATTTTCCCAATTTCTCAGACCTTACACTGCTTTATCTTCAGCCTCCGAGGGCTTTTGCCTTCACGCTGGTCTGGTTTTTCGTGAGTCTGGTGTCGTTTCTCTGTTTCTCCAGAGCTTTTGACTCTCCTCTTGTTGGCCTGGAGGGGGTTTATTCATTTTCTGTGCCTTTACTGTCAGCAACGGTGGGGTCTCTTCATTTCTGCCCCTTCAACCTCTAACCGAGTTGAGCTTGTTCTTTAAGATCCGTCAGAGAGTCAGTCTGAAAAATGAATCCAAGAGAAATTCTCTGAGAAATGTCATGTTTCTGTCTTCAGCCTCTGATTGTTGCTGTCAGCCAAAATCAACCAGTCTAGAGTCTAGTTTGAGTTTTAAAATGATGCAAGCATACTGAATACTGTAGGGTTTGTAATCTAgtgtttgctgtttgttgaaAAGAGGCATTTTAATTTGTTCTTGCACTAAAGAAAGTTGCttgaagtgatagttcacccaaaattatagttcattcatttttttatgcatgtttgaaaccagttttagttttattttctgttgaacacaaaggaaaatgTATTGAAGaatggaaaaaaacagccattgacttgaGTAGTATTACTTTGTTCCTACTTTGGATGTCAAATATctgctttttcattatttttcaggATATCATGTTTTGTGTTCTACACAAGAAAGAAATACATTAATGTTTACAACTAATTGAGcatgaaataatacattttaaattttttttgagtgaactatccctttaaaatgtttttagaaataaggGATCTCTTTTTAGATTTGTATTGATCCATGTGTGGCGTTAATGTCACATTTTAACTCGATGCCACATCAATTTTGCACTGTGTTAATAGACATTTTGTATTCAGAGAATACCAAGTTGTTCTCAGGAAAATCAATACTTGTGGTTTAATCGGCAATCACTTTATCAATAGCGATAGACTAAAGGGAcgaatgtgtgtatttttgagtccTCTCTGGCTGTTTGCCAACAGATTAGCTGCTCGAGACTGTTTGAAGTTGATGGTTTATCAATTTTTGCCTTTTTGTGCTACTGTATCAGtcatgattttaaataaaatgctttttaaggT

Function

symbol description
ctsc Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in cellular protein catabolic process. Predicted to act upstream of or within proteolysis. Predicted to be active in extracellular space and lysosome. Is expressed in macrophage; neural crest; polster; somite; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Papillon-Lefevre disease and aggressive periodontitis. Orthologous to human CTSC (cathepsin C).

GO:

id name namespace
GO:0006508 proteolysis biological_process
GO:0051603 proteolysis involved in cellular protein catabolic process biological_process
GO:0005764 lysosome cellular_component
GO:0005615 extracellular space cellular_component
GO:0004197 cysteine-type endopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008234 cysteine-type peptidase activity molecular_function

KEGG:

id description
ko04142 Lysosome
ko04210 Apoptosis
ko01002 Peptidases and inhibitors
ko03110 Chaperones and folding catalysts
ko04147 Exosome

ZFIN:

id description
ZDB-GENE-030619-9 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in cellular protein catabolic process. Predicted to act upstream of or within proteolysis. Predicted to be active in extracellular space and lysosome. Is expressed in macrophage; neural crest; polster; somite; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Papillon-Lefevre disease and aggressive periodontitis. Orthologous to human CTSC (cathepsin C).

Ensembl:

ensembl_id ENSDARG00000101334

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00018677 True 3145 mRNA 0.44 7 43604032 43625549

Neighbor

gene id symbol gene type direction distance location
XLOC_009515 NA coding downstream 91960 43510550 ~ 43512072 (-)
XLOC_009514 prss16 coding downstream 276121 43286785 ~ 43327911 (-)
XLOC_009513 serpine2 coding downstream 320011 43241915 ~ 43284021 (-)
XLOC_009512 wdfy1 coding downstream 365812 43208593 ~ 43238220 (-)
XLOC_009511 NA coding downstream 416489 43173142 ~ 43187543 (-)
XLOC_009517 NA coding upstream 18295 43643844 ~ 43650523 (-)
XLOC_009518 CABZ01044962.1 coding upstream 26097 43651646 ~ 43651761 (-)
XLOC_009519 grm5b coding upstream 30692 43656241 ~ 43768776 (-)
XLOC_009520 CABZ01073033.2 coding upstream 199123 43824672 ~ 43873005 (-)
XLOC_009521 chordc1a coding upstream 336265 43961814 ~ 43978141 (-)
XLOC_009509 BX890602.1 non-coding downstream 484841 43073923 ~ 43119191 (-)
XLOC_009507 CR457441.1 non-coding downstream 875446 42728470 ~ 42728586 (-)
XLOC_009504 NA non-coding downstream 1046035 42551423 ~ 42557997 (-)
XLOC_009523 NA non-coding upstream 373981 43999530 ~ 44020074 (-)
XLOC_009524 NA non-coding upstream 391884 44017433 ~ 44017563 (-)
XLOC_009528 NA non-coding upstream 493684 44119233 ~ 44123107 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000242_00155203_00163066 CTSC coding CI01000242 null 155119 ~ 163290 (+)