CI01000037_00324040_00344658 (BMPR2, BMPR2B)


Basic Information

Item Value
gene id CI01000037_00324040_00344658
gene name BMPR2, BMPR2B
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000037
NCBI id null
chromosome length 4612320
location 322308 ~ 344776 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000037_00324040_00344658.mRNA
CTTTATATTGCAGGAAGGTTGTGTCTGCATACTGTTGCCAGGCATCGTGAGTGGGAGTCAGTGATATCAAAGAAGAGTTCTGGTTACCCAGGGAAACTGCATCTGTCCTGAAGATCGGTCTCAAAGAATGTGAAGGACAGAAGTTCAGATCCATGCGTGATGCGAGGACAAACACGAGGCTACAGAGAGAAACAAAGTCTTTTATTGTATCATTCCATGTGTCTCCATGAAGGTCTTCTGTTGTAGCACATAACATGGCAAAAGAAGCATGTAACATGACAGGAAGTTATTACGCGTGTTAAAAGCCATTACACTACTGTGGCAGTACCACGGTACAGTGATGATGGTAGATGGTAATAGCATAGCACAAAAAATTATCAAAATGCTTTTTTTTGTCTTCGTTTTGAACAGTATATCTGCTATTTTATCATTTTAAAACTTTGTCCATTATTTTGTTTAAAGTGTATCTGTGGTTATTTTCAAATGCATTGATTTTAAAGGATTAGTCCACTTTCAAATAAAAATTTCCTGATAATTTACTCACCCCCATGTCATCCAAGATGTCCATGTCCTTCTTTCTTCAGTCGAAAAGAAATTAAGGTTTTTGATGAAAACATTCCAGGATTATTCTCCTTATAGTGGACTTCAATTGGCCCCAAACGGTTGAAGGTCAAAATTACAGTTTCAGTGCAGCTTCAAAAGGCTTTAAACAATACCAGACAAGGAATAAGTGTCTTATCTAGCGAAACGATCAGTCATTTTCTAAAAAAAAAAAAAAATTATCTACATTTTAACCATTGACGCTCATCTTGAACTAGCTCTCTTCTTCTTCTTCTCTATTAGAATTCCAGCAGTGTATACGCTGCTAAGTGTATTACTGCCCTCCACAGGTCAAAGTTTGAACTAATTGTTATATACTTGCACTAGCATATTGTATATGACAATTTAGTTCAACATTTGACCTGTGGAGGGCAGTAATACACTTAGCAGCGTCTACACTGTGTCCATTGTTTTCAATGACAAATAATTTGTCTGTTCACACTGACCATAAAACTATTTTGTGATGTGGCGATCACAGCCAGTTAGAAGATATTTGATGTTTAATATACTGTTATACTGTTTTAATCCACTTATTTCACTGTTGCCGGGGATACTCAGAAATTTATCTGCAAATACTTTTGGTAAAAACCATGGTATTGAATGATTGCCATTTTGATATACCATAGTATTTGCATTTTATTCCATGGTAATTCAAAGAATATAATAGTAACCATAATTCTTACCATAATTAATTCTTTGCTGAATAAAATTATGCATTTTTTTTTTTTTTTTTTTTTTAGTTACCCCAAACTTATGAATTCACACAATTTTCCACAAAAATATGAAGCAGCACAACAGTTTTCAACATAAATAATAATAAGAAGAAATGAGCACCAAATCACTATATTAGAATGATTTCCGAAGGATCATGTGACTCTGAAGACTGGAGTAATGATGCTGAAAAAAATCAGCTTTGCCATCAGAGGAATAAATTACATTTTAAAATATATTAAAATAGAAAACAGTTTTAATAACATTTCTCTATTACAGTTTTCACTGTATTTTTTGATCAAATACATGCAGTCCTGGTGAGCATAAAATACTTCTTTCAAAAACATTAACACATCATAATTATTCAAAATGTTGACAGGTAGTATAATGGAGGCGTGAGAAAGGAAGGAGAGCTCTCATAATGCACGGAGTCCTGGAGGGAGACGTACAGGAAGTACAACAGGATTGTTGGTATAGTCTGGAAGAGGGAGGGACACTCAGACATTCTGCCTCCGAGCTAAATGCCGCCGGCTCCAAGACATCTGCTGCAGTGGACCTGGGAGGGTCCAGCTCAAAAATATGGGCAGGAGTGTGGATTTGTATCTATATTGTATTCACTGCATTGAAGATAAACACAGCTAAATTCCACATTTCTTGCTATATTCTGCATGCGTCAATCCTAAAATCCATTAAAATATATCAACAGCCTTTACACAGAGATGAGGCCATCTTCATTGCCCTCGCGTCTGTCTCCATAGTAGCGGTCCTGATTGTGGCACTGTTGTTCGGCTATCGCATGATGATGGGCGAGTGTAAACAAGGCCTGCACAACATGGACATGATAGAGGCCGCACCATCAGAACCATCTCTGGATTTAGACAGTTTAAAACTACTGGAATTGATTGGTCGAGGGCGCTATGGTTCTGTCTACAAAGGATCTCTTGATGAACGCCCGGTTGCTGTAAAAGTTTTTACCTATGCCAACCGGCAAAACTTTGTGAATGAGCGCTCCATCTACCGAATCCCTCTTCTGGAGCATGATAACATTGCTCGTTTTATCGTTGGGGATGAGCGTCTCACGGCAGATGGGCGGATGGAGTACCTGCTGGTCATGGAGTACTACCCTCATGGTTCTCTGTGCCGGTACCTGAGTCTGCACACGTTGGACTGGGTGAGCTGCTGTCGTCTGGCACATTCGCTCACGAGAGGACTGGCCTACCTTCACACTGAGCTCCTGAGAGGAGATTTATATAAACCTGCCGTGTCACACCGGGATCTAAACAGCCGTAATGTTCTGGTGAAGAACGATGGCACAACGGTGATCAGCGATTTTGGTCTGTCCATGAAACTGACAGGAAATCGCCTCGTACGGCCTGGTGAAGAGGAAAACGCCGCCATCAGTGAGGTGGGCACAATCCGCTACATGGCCCCGGAAGTGCTGGAGGGAGCGGTGAACCTCAGGGACTGTGAGTCGGCTTTGAAACAGGTGGACATGTATGCCATCGGCCTCATCTACTGGGAAACCTTCATGAGATGCACTGACCTTTTTCCAGGGGAGGCAGTGCCAGAATACCAGATGGCCTTCCAGGCCGAGGCGGGGAACCACCCCTCCTTTGAGGACATGCAGGTGCTGGTGTCCAGAGAGAAACAGAGACCAAAGTTCCCAGAAGCCTGGAAGGAGAACAGCCTGGCTGTGCGCTCTCTGAAGGAGACTATGGAGGATTGCTGGGATCAGGACGCAGAGGCTCGTCTGACGGCCCAGTGTGCAGAGGAACGTATGGCAGAACTGCTGCTGATCTGGGAGAGGAACAAACCTGTCAGCCCCACCATCAATCCCATGAGCACAGCGCTGCAGAACGAGAGGAATCTCACCCATAGTCGCAGGGTTCCCAAAATGGGCTCTTATCCAGATTACTCTTCATCCTCTTACATTGAGGATCATGAGGGCATGGTGAAGAACCTCCCAGGTGACGTCTCAACATCTGGGACTTCCTCTGTGGCTGGCATGGCCGTGAGCGGCATTAGCAGTGGCGTGACAGCGACAGGAGAGAAGAACAGAAACTCCATCAACTATGAGAGACAGCAGGCTCAGGCACAAGCTCGGCTGCCCAGCCCAGAGACCAGCGGCACTAGCCTGTCCGCCACGACCACTACGACGGGCCTCACACCCAGCACCATCATGACCACCATCTCTGAATCAGGCCACTCAGAGGAAGCAGGGGCCGGAGGAAGTGTACCAGTGTGCCTGCAGCTCACAGAAGAAGACCTGGAGACCACCAAACTGGACCCCAAAGAGGTGGATAAGAACCTGAAAGAAAGCTCTGATGAGAACCTGATGGAGCATTCGCAGAAGCAGTTCAGCGCTCCCGACCCGCTCAGCTCGGGCAGCTCCAGCCTCTTGTACCCACTTATCAAACTTGCTGCGGAAGTGACCGGAGGGTCCGGGTCCGGTGGCCAGGCCGATTTCGGGGTGGGCAGCAGTGGAATGGGCGACGCTCCTGCAGCTATGTTCCCACTCCCCAAACAGCAGAATCTCCCCAAGCGGCCCACCAGCCTGCCCCTCAACACCAAAAATCCCGGCAGGGAGTCCTCTTCGTCACGCCTGAAGTTCGGCAAGCACAAGTCCAACCTGAAGCAGGTGGAGACGGGCGTAGCCAAGATGAACACTGTAGTGGCCGTCGAGCCTCACTTGGTCACCGTCACTAACAATGGACCCAGTGTCCGTAGCGGCGTCGGAGTGGTCGTTGTTAACGGATATGGTGGGGTCAATGGTGCCGGTTCCTCTGATGCATTTGGGAACACGAACCCAGCCGGGCCACAGGGTGAGGGCAGTGCCCCTCTGCTCCAGAGCCAGCTGAGTGGAGAAGACAGCCGTCTCAACATCAACATCAACTCCAGCCCAGACGAACACGAGCCCCTGCTGAGGAGAGAGCAGCCGGCCCCGCGTGATCACTCCGGCCGCACCAACTCAAATAACAACAACAGCAACATCCACACAAATGCCTCTGCCACAGTTCGTACGTTAGCTCCTGCAGATGCCCAGATTGAGACTTTAACCTGCTCTCTGGGGGCACCAGACGGAAGGGCTGATGGGGTTCCACTGAGACAGCCTAAACCCAGGAGACCTGAGCGGCCAAACTCACTGGACCTGTCAACAACTTCCCAGGATTCATCTCTCTTGGATGAGGCCGTGTCACAAGAGGGAAAAGCTGGATCAGCTGAGAAGATAAAGAAGCGTGTGAAGACACCTTATTCTTTGAAAAGATGGCGTCCTTCCACTTGGGTTGTCTCTACAGAAACCCTGGATGGAGAGGTCAACAATAACGGGCACAGCCAGCAGACGGGGATGGCAGTGACTGGAGGTGGCCACCCAAGTTCTGGCCAATCAAAATCCAGCATCGCTGTGTTCCTGGTCAGCGGCGGAACCGCGACCGCCACTCTAACCTCCGACCCACCAGATATGACCTGCCTGTGAACTCACATCTCTGCTTTTCCTCTGAGGAAGAGCCCAGATCAGACTTTGAACACAAGAGGGGTTTGTCTATGCTATCGTGCTCCAAGAACTAATCCAGTTGATGACGGAAAGAAATACA

Function

symbol description
bmpr2b Enables transforming growth factor beta-activated receptor activity. Acts upstream of or within BMP signaling pathway; embryonic organ morphogenesis; and vasculature development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including blood island; cardiovascular system; gonad; gut; and posterior pronephric duct. Human ortholog(s) of this gene implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease. Orthologous to human BMPR2 (bone morphogenetic protein receptor type 2).
bmpr2 Enables BMP binding activity; cadherin binding activity; and protein tyrosine kinase binding activity. Involved in several processes, including negative regulation of cell population proliferation; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and regulation of blood pressure. Acts upstream of or within positive regulation of SMAD protein signal transduction. Located in adherens junction; nucleoplasm; and plasma membrane. Is integral component of plasma membrane. Colocalizes with caveola. Implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease. Biomarker of asthma and pulmonary hypertension.

GO:

id name namespace
GO:0048570 notochord morphogenesis biological_process

KEGG:

id description
K04671 BMPR2; bone morphogenetic protein receptor type-2

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000037_00324040_00344658.mRNA True 4904 mRNA 0.47 12 322308 344776

Neighbor

gene id symbol gene type direction distance location
CI01000037_00296900_00315382 NA coding upstream 6625 296900 ~ 315683 (+)
CI01000037_00237846_00258273 NA coding upstream 63558 236927 ~ 258750 (+)
CI01000037_00231425_00233108 NA coding upstream 89200 231425 ~ 233108 (+)
CI01000037_00228809_00230442 NA coding upstream 91578 228809 ~ 230730 (+)
CI01000037_00208728_00215104 GLB1L coding upstream 107204 208160 ~ 215104 (+)
CI01000037_00348422_00394107 FAM117BB coding downstream 3646 348422 ~ 394107 (+)
CI01000037_00406888_00413827 CARF coding downstream 62112 406888 ~ 414156 (+)
CI01000037_00578227_00598603 NA coding downstream 233451 578227 ~ 598836 (+)
CI01000037_00606067_00621968 MPP4A coding downstream 261291 606067 ~ 621968 (+)
CI01000037_00625438_00630273 TMEM237A coding downstream 280662 625438 ~ 630310 (+)
G174500 NA non-coding upstream 104460 217628 ~ 217848 (+)
G174445 NA non-coding upstream 253647 65818 ~ 68661 (+)
G174551 NA non-coding downstream 73706 418482 ~ 422646 (+)
G174562 NA non-coding downstream 113107 457883 ~ 460548 (+)
G174576 NA non-coding downstream 152303 497079 ~ 497372 (+)
G174580 NA non-coding downstream 158970 503746 ~ 503978 (+)
CI01000037_00633378_00678193 ABI2, ABI2A non-coding downstream 288562 633338 ~ 679180 (+)
CI01000037_00987906_00988350 NA other downstream 643083 987859 ~ 989246 (+)
G174949 NA other downstream 1269100 1613876 ~ 1614274 (+)
CI01000037_01965864_01966433 COA5, CB064 other downstream 1620966 1965603 ~ 1966435 (+)
G176346 NA other downstream 2494984 2839760 ~ 2840053 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00001334 NA coding CM030137.1 CM030137.1 25552444 ~ 25581376 (+)