XLOC_000928 (gart)


Basic Information

Item Value
gene id XLOC_000928
gene name gart
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 960209 ~ 999556 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001483
ATGTCTGAGCGTGTGCTGGTCATTGGTAGCGGCGGTCGGGAACATGCGCTGGCCTGGAAGTTTGCTCAGTCTCCTCATGTCCAGCAGGTCCTCGTGGCTCCGGGAAACGCAGGAACCGCGAACTGTGGGAAAATCTGCAACTCCGAGGTGTCCGTGAACAATCATTCGATTTTAGCTCAGTATTGTAAAGATCATAAGGTGGGACTGGTGGTGGTGGGTCCAGAAGTTCCTCTGGCCGCTGgtATGGTGGATGACCTGACGGCCGCTGGTGTGTTGTGTTTCGGGCCGTCGGCGAGGGCCGCTCAGCTGGAGGCCAGTAAGAGTTTCTCCAAAGCCTTCATGGATCGACACAACATCCCCACGGCCCGCTGGAGCTCCTTCACTGACCCGCAGCAGGCCTGCGCTTATATTCGAgatgctgATTTCCCGGCTCTGGTGGTAAAAGCGAGCGGTCTGGCGGCTGGGAAAGGTGTGATCGTCGCTCAGGATAAAGATGAAGCCTGTCAGGCGGTGCTGGACATCATGAAGGATAAGGCGTTCGGTTCAGCGGGAGAGACTGTGGTTGTGGAGGAGCTGCTGGATGGACAGGAAGTGTCTTGTTTGTGTTTCAGTGATGGTGTGACGGTCGCACCGATGCCTCCAGCTCAGGACCACAAGCGTCTGCTGGATGGAGATATGGGGCCGAACACTGGCGGGATGGGGGCTTACTGTCCCACACCACAGgtttcaGATGAACTGCTGCAGGAGATCAGCAGAAGTGTTCTTCAGAAGACTGTGGATGGTATGAGAGAGGAGGGAGCGCCGTATGTGGGTGTTTTATACGCAGGGCTGATGTTGACTGCGCAGGGACCGAGGGTGCTGGAGTTCAACTGCCGCTTCGGTGACCCCGAGTGCCAGGTGCTGCTCCCGCTGCTGCAGTCAGACCTGTATGAGGTGTGTATGCAGACGCTGCGCTGTGAGCTGGACTCCGCTTCAGTGCAGTGGCTGCAGGACTGTGCTGCGGTGACTGTGGTGATGGCCAGCGGAGGATACCCAAATGCTTACAGAAAGGGTCTGGAGATTAGCGGTTTGTCTCAGGCGTCAGAGATGGGCGTTCAGGTGTTTCATGCTGGCACTGCTGTTAAAGAAGGGGGCGGAGTCATCACAAGTGGTGGGCGTGTCCTGACGGTCACTGCGGTCCGGCCCACTCTGGAGAGTGCTTTACAGAGCGCTAACGAAGGAGTGGCAGCGATCAGCTTTCCTGATGCGGTTTACCGGAGAGACATCGGCCACCGCGCCATCACATACCTCACACACACCAGAGGATTGACGTATAAGGACAGTGGTGTGGACATCGCTGCGGGAAACAGACTAGTAGACATCATCAAACCTTTAGCCAAGGCAACATCTCGTCCAGgatgtAATGCTGATCTCGGTGGTTTTGCGGGGCTCTTTGATCTGAAGGCTGCAGGATTCACCGACCCCATATTGGTGTCAGGGACTGATGGAGTCGGCACGAAGCTGAAGattgcACAGGAGTGTGGTGTTCACAGCACTCTGGGTCAGGATCTGGTGgccatgtgtgtgaatgatgtcCTCGCTCAGGGAGCCGAGCCGCTCTTCTTCCTGGATTATTTCTCCTGCGGTCGGCTGGATGTCGACGTTGCGGCTTCGGTCATCGGCGGCATCGCAGACGCCTGTCAGATGGCTGGATGTGCTCTGTTAGgaggtGAGACGGCGGAGATGCCGGGTGTGTATCCTCCAGGAGAGTATGATCTGGCTGGGTTCTGTGTGGGAGCAGTGGAGCGCTCCGCTCTTCTGCCCAGACTGAAGGACATCTCAGAGGGAGATCTGCTGCTGGGCGTGTCCTCCTCTGGCATACACAGCAACGGCTTCAGTCTAGTGCGCACGATCCTGGAGCGCAGCGGCCTAAACATCAGCTCACCTGCGCCGTTCGGCCGTCCTGGACAGACTATCGGAGATGTTCTTCTGACTCCCACTAAGATCTACAGCCGTGCCCTCCAGCCTGTGCTGCGCAGTGGAGCCGTGAAAGCGTTCGCTCACATCACCGGTGGAGGACTGCTGGAGAACATCCCTCGAGTCCTGCCTGCGGATCTGACTGCGGATCTGGcaacatttttattttacattaacccATACATGCCTCATTTCACAGAGTATTCTGGAGTATTCTTGCTTTCgttatttatgttttataaattgtcatttggttatttatattatattagttatatATTGGCTAACGTATATCTTTgtctgcgtCAGGCCCACGAAGAGAGCTGGATCATTGGCTCCCTCACACACAGACACCCTGgagCAGAGTCTGTGGTGGTTAGAAACCTGGAGCGGAGTCTTCGGGCTGGGCCAGACTGCTCTCCGGACACCTGCATGCTGCGGAACGGATCAGCAGCAGCGGATCAGAACTCACGGCGCAGGACCAGAGTCGCTGTGCTCATCTCTGGAAGCGGTATtattatgatgatgatgatggttaaGATGAAGATGCCTATTAtgacagtgatgatgatgatgactattATGACCCCAAAAGCAGTGTTTGTTTTGATTCGGTGCTCatttgttggtgtgtgtgtgtgtGTTGTGGATCATAAGCTGTACGGCAGCAGAGCAGAGTTTGACGGCACCATTGATAAAGTTCTGGAGGAGTTCAGTGTGGAGCTGGTGTGTCTGGCAGGATTCATGCGCATCCTCACCGGACCCTTCGTACGCAAGTGGAGCGctaatgaacacagcagaaCATCACTTTCTGTCTTC
>TCONS_00001484
ATGTCTGAGCGTGTGCTGGTCATTGGTAGCGGCGGTCGGGAACATGCGCTGGCCTGGAAGTTTGCTCAGTCTCCTCATGTCCAGCAGGTCCTCGTGGCTCCGGGAAACGCAGGAACCGCGAACTGTGGGAAAATCTGCAACTCCGAGGTGTCCGTGAACAATCATTCGATTTTAGCTCAGTATTGTAAAGATCATAAGGTGGGACTGGTGGTGGTGGGTCCAGAAGTTCCTCTGGCCGCTGgtATGGTGGATGACCTGACGGCCGCTGGTGTGTTGTGTTTCGGGCCGTCGGCGAGGGCCGCTCAGCTGGAGGCCAGTAAGAGTTTCTCCAAAGCCTTCATGGATCGACACAACATCCCCACGGCCCGCTGGAGCTCCTTCACTGACCCGCAGCAGGCCTGCGCTTATATTCGAgatgctgATTTCCCGGCTCTGGTGGTAAAAGCGAGCGGTCTGGCGGCTGGGAAAGGTGTGATCGTCGCTCAGGATAAAGATGAAGCCTGTCAGGCGGTGCTGGACATCATGAAGGATAAGGCGTTCGGTTCAGCGGGAGAGACTGTGGTTGTGGAGGAGCTGCTGGATGGACAGGAAGTGTCTTGTTTGTGTTTCAGTGATGGTGTGACGGTCGCACCGATGCCTCCAGCTCAGGACCACAAGCGTCTGCTGGATGGAGATATGGGGCCGAACACTGGCGGGATGGGGGCTTACTGTCCCACACCACAGgtttcaGATGAACTGCTGCAGGAGATCAGCAGAAGTGTTCTTCAGAAGACTGTGGATGGTATGAGAGAGGAGGGAGCGCCGTATGTGGGTGTTTTATACGCAGGGCTGATGTTGACTGCGCAGGGACCGAGGGTGCTGGAGTTCAACTGCCGCTTCGGTGACCCCGAGTGCCAGGTGCTGCTCCCGCTGCTGCAGTCAGACCTGTATGAGGTGTGTATGCAGACGCTGCGCTGTGAGCTGGACTCCGCTTCAGTGCAGTGGCTGCAGGACTGTGCTGCGGTGACTGTGGTGATGGCCAGCGGAGGATACCCAAATGCTTACAGAAAGGGTCTGGAGATTAGCGGTTTGTCTCAGGCGTCAGAGATGGGCGTTCAGGTGTTTCATGCTGGCACTGCTGTTAAAGAAGGGGGCGGAGTCATCACAAGTGGTGGGCGTGTCCTGACGGTCACTGCGGTCCGGCCCACTCTGGAGAGTGCTTTACAGAGCGCTAACGAAGGAGTGGCAGCGATCAGCTTTCCTGATGCGGTTTACCGGAGAGACATCGGCCACCGCGCCATCACATACCTCACACACACCAGAGGATTGACGTATAAGGACAGTGGTGTGGACATCGCTGCGGGAAACAGACTAGTAGACATCATCAAACCTTTAGCCAAGGCAACATCTCGTCCAGgatgtAATGCTGATCTCGGTGGTTTTGCGGGGCTCTTTGATCTGAAGGCTGCAGGATTCACCGACCCCATATTGGTGTCAGGGACTGATGGAGTCGGCACGAAGCTGAAGattgcACAGGAGTGTGGTGTTCACAGCACTCTGGGTCAGGATCTGGTGgccatgtgtgtgaatgatgtcCTCGCTCAGGGAGCCGAGCCGCTCTTCTTCCTGGATTATTTCTCCTGCGGTCGGCTGGATGTCGACGTTGCGGCTTCGGTCATCGGCGGCATCGCAGACGCCTGTCAGATGGCTGGATGTGCTCTGTTAGgaggtGAGACGGCGGAGATGCCGGGTGTGTATCCTCCAGGAGAGTATGATCTGGCTGGGTTCTGTGTGGGAGCAGTGGAGCGCTCCGCTCTTCTGCCCAGACTGAAGGACATCTCAGAGGGAGATCTGCTGCTGGGCGTGTCCTCCTCTGGCATACACAGCAACGGCTTCAGTCTAGTGCGCACGATCCTGGAGCGCAGCGGCCTAAACATCAGCTCACCTGCGCCGTTCGGCCGTCCTGGACAGACTATCGGAGATGTTCTTCTGACTCCCACTAAGATCTACAGCCGTGCCCTCCAGCCTGTGCTGCGCAGTGGAGCCGTGAAAGCGTTCGCTCACATCACCGGTGGAGGACTGCTGGAGAACATCCCTCGAGTCCTGCCTGCGGATCTGACTGCGGATCTGGcaacatttttattttacattaacccATACATGCCTCATTTCACAGAGTATTCTGGAGTATTCTTGCTTTCttatttatgttttataaattgtcatttggttatttatattatATTGGCTAACGTATATCTTTgtctgcgtgtgcgtCAGGCCCACGAAGAGAGCTGGATCATTGGCTCCCTCACACACAGACACCCTGgagCAGAGTCTGTGGTGGTTAGAAACCTGGAGCGGAGTCTTCGGGCTGGGCCAGACTGCTCTCCGGACACCTGCATGCTGCGGAACGGATCAGCAGCAGCGGATCAGAACTCACGGCGCAGGACCAGAGTCGCTGTGCTCATCTCTGGAAGCGGTATtattatgatgatgatgatggttaaGATGAAGATGCCTATTAtgacagtgatgatgatgatgactattATGACCCCAAAAGCAGTGTTTGTTTTGATTCGGTGCTCatttgttggtgtgtgtgtgtgtGTTGTGGATCATAAGCTGTACGGCAGCAGAGCAGAGTTTGACGGCACCATTGATAAAGTTCTGGAGGAGTTCAGTGTGGAGCTGGTGTGTCTGGCAGGATTCATGCGCATCCTCACCGGACCCTTCGTACGCAAGTGGAGCGagatgatgatgaaaagctcaaacacactgcttccttctgtgacaacatgggaaaatcaacaacaaAGCAGCCAGATTACAGttagcatagatggcatcatgaaacattttataaaaGAGGATGTGGACGCCGGAGCCATTGTGGTCCAGGAGGCGGTTCCTGTGCTGGTGACTGACAGCGAGGAGAGCCTATCAGAGCGCATCAGAGAGGCGGAGCATCGGGCGTTCCCAGCAGCCTTGGAGCTGGTGTCCAGTGGAGCGGTGAAGCTCCGAGACGACGGACACATCGTGTGGAGCACCAGAGAGACACACTAA

Function

symbol description
gart Predicted to enable phosphoribosylamine-glycine ligase activity and phosphoribosylformylglycinamidine cyclo-ligase activity. Acts upstream of or within camera-type eye development; chordate embryonic development; and pigmentation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytosol. Is expressed in several structures, including alar plate midbrain region; digestive system; nervous system; pigment cell; and yolk syncytial layer. Orthologous to human GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase).

GO:

id name namespace
GO:0008152 metabolic process biological_process
GO:0043009 chordate embryonic development biological_process
GO:0043010 camera-type eye development biological_process
GO:0009058 biosynthetic process biological_process
GO:0046084 adenine biosynthetic process biological_process
GO:0006164 purine nucleotide biosynthetic process biological_process
GO:0009113 purine nucleobase biosynthetic process biological_process
GO:0006189 'de novo' IMP biosynthetic process biological_process
GO:0043473 pigmentation biological_process
GO:0005829 cytosol cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0016740 transferase activity molecular_function
GO:0016742 hydroxymethyl-, formyl- and related transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004637 phosphoribosylamine-glycine ligase activity molecular_function
GO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity molecular_function
GO:0004644 phosphoribosylglycinamide formyltransferase activity molecular_function
GO:0016874 ligase activity molecular_function
GO:0003824 catalytic activity molecular_function

KEGG:

id description
ko00230 Purine metabolism
ko00670 One carbon pool by folate
ko01523 Antifolate resistance

ZFIN:

id description
ZDB-GENE-000616-14 Predicted to enable phosphoribosylamine-glycine ligase activity and phosphoribosylformylglycinamidine cyclo-ligase activity. Acts upstream of or within camera-type eye development; chordate embryonic development; and pigmentation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytosol. Is expressed in several structures, including alar plate midbrain region; digestive system; nervous system; pigment cell; and yolk syncytial layer. Orthologous to human GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase).

Ensembl:

ensembl_id ENSDARG00000101089

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001483 False 2775 mRNA 0.55 24 960209 999556
TCONS_00001484 True 3048 mRNA 0.55 28 973467 999556

Neighbor

gene id symbol gene type direction distance location
XLOC_000927 NA coding downstream 180595 778575 ~ 779614 (-)
XLOC_000926 adamts5 coding downstream 245583 691738 ~ 714626 (-)
XLOC_000925 adamts1 coding downstream 279093 673163 ~ 681116 (-)
XLOC_000924 cyyr1 coding downstream 290492 658405 ~ 669717 (-)
XLOC_000923 appa coding downstream 303516 617620 ~ 656693 (-)
XLOC_000929 NA coding upstream 6381 1005937 ~ 1014866 (-)
XLOC_000930 CU611053.1 coding upstream 51385 1050941 ~ 1051057 (-)
XLOC_000931 NA coding upstream 144406 1143962 ~ 1253194 (-)
XLOC_000932 NA coding upstream 291619 1291175 ~ 1315753 (-)
XLOC_000933 CZQB01066256.1 coding upstream 350555 1350111 ~ 1352997 (-)
XLOC_000907 FP067451.1 non-coding downstream 812363 108285 ~ 147846 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000299_05392812_05418070 GART coding CI01000299 null 5392692 ~ 5418352 (+)