XLOC_011849 (PLCB1)


Basic Information

Item Value
gene id XLOC_011849
gene name PLCB1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007128.7
NCBI id CM002901.2
chromosome length 53461100
location 3841012 ~ 3986236 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00023426
ATGGCTGGAGCTCAACCTGGCGTTCACGCGCTTCAACTCAAGCCGGTGCGCGTGTCCGAGAGCCTGAAGCGAGGCAGCAGATTCATGAAATGGGATGAGGATTCTTCAACAGTGACTCCAGTGACGTTACGTGTGGATCCGCAGGGATATTTCCTGTACTGGACTGATCAGAACAAGGAAACTGATCTGCTGGACATCAGCTACATTAAAGATGCCAGAACGGGGAAATGCACCAAAACACCAAAGGAAGCAAAGCTCCGGGAGCTCCTGGATGTGGGGAATCTGGTGGGACGGATAGAGAACCGGATGCTGACGGTGGTGACTGGACCCGACATGGTCAACATCCAGTACCTGAACTTCATGGCCTTCCAAGAAGACGTCGCCAAGGAGTGGGCAGATGAGCTGTTTAGTCTGGCCTCAAACCTGCTGGCTCAGAACATGTGCAGAGAGTCCTGTCTGGAGAAAGCCTTCACAAGACTCAAGCTGCAGACAAATCAAGAGGGTCGAATCCCTGTGAAAAATGTTTCCCGCGTGTTCTCCACGGACCGGAAGCGTGTGGAGACAGCGCTGGAGAGCTGTAATCTGCCGTCCGGCCGGGTGAGCATATCGAAGAGCAGAAACTATCTGAGCATGGAGCAGATGACTGAGTTCATCAATAATAAGCAGCGAGACCCTCGTCTGAATGAGATCCTGTACCCGCCGCTGAAGCCCGACCAAACACACGCCCTGATGGAGAAGTTTGAGCCCAACGCCGAGTTCATTCAGAAAGGGCAGATCTCAGTGGAGGGCTTCTCCAGATACCTGATCAGCGAAGACAACAGCGTCATCCCTCCAGAAAAACTGGACCAGAGTGAAGACATGACATACCCTCTGTCTCAGTACTTCATCAACTCATCCCACAACACATACCTCACAGgtacagcaaacacacacgcatgctttagagttggagctaaactgtgcaggacactatcAAATGCATTTTTAAGACTAATTGAAATAATCGCTGTTGTTTTGCAGGAAGTGATTGAAGCCATAGCGGATTGTGCATTTAAAACATCTCCGTTTCCTGTCATTCTGTCCTTTGAGAATCACGTGGACTCCCCCAAACAGCAAGCCAAAATGGCAGAGTACTGCCGGTCCATCTTCGGGGACGCTTTACTGACCGAGACGCTGGAGAAATATCCGcTGGAGCCTGGAACTCCTCTACCCAGTCCTCAAGAGCTCATGGGCAAAATCCTCATCAAGAACAAGAAATCTCACCCCAAAGCAGCCGATGGCAGCACCAAAAAAAAGCTGTCTGAGCAGGCGTCCAACACCAACAGCGACTCCTCCAGTGTTTTCGAACCATCTTCTCCCAGCGCTGGCCCTGCAGGTACTCAGAAGAGTCAGAGCCATGTACTGTTGATTTCTATGGTAATAATGCATTGCTTATCAATTTTACATGTAAATAATTCTAAATGTAaTAGGTCACTAATGTTCATTAGACTGTCTCCtgagtgttgtgttttattaatatctgcTCATCTTGATCTACAGATCATATCAGGTCAGTTTCTGACTGACAGGAAGGTGGGCGTTTATGTGGAGATTGACATGTTTGGACTTCCAGTCGACACAAGACGAAAAGCGTTCAAGACAAAGACGTCCCAGAGCAATGCCATCAACCCGGTGTGGGATGAGGAGCCCATCGTCTTCAAGAAAGTGGTGCTGCCCACATTGGCTTCCCTGAGGATCGCAGTGTTTGAGGAGGGAGGAAAGTTCATCGGTCATCGCATCATTCCCGTCTACGCCATCCGCCCCGGTTATCGTTACATTGGTTTGAGAAATGAGAAGAATCAAGGGCTCACTCTTCCTGCTTTATTCGTCTATATCGAGGTGAAAGACTACGTGCCTGATACTTTCGCTGATGTGATTGAAGCGCTGTCCAACCCCATCAGATACGTCAACCTGATGGAGCAGAGATCCAAACAGCTGGCGGCACTGACACTGGAGGAGGGAGAGGAGGAGAAGGACACCAAAGAGGTAAACACTGCTTCCACATTCACTGGATTAAACAACTATTATAATGGGATTAACGCACTAATTGCTTCACTACATTATGGACAAACAATTCATATTATTGGCTCGACAAAACCGGCAGCAAAGACTGAAGATCTGATCCACAGCGTCCTCACCGAGATGGAGGCTCAGAGTGTGGAGGAGCTCAAACAGCAGAAGGGATTTGTGCGCGAACAGCGACGGCACTATAAAGAGATGAAGGACCTGGTGAAGAAACACCACAAGAAAACCACAGAGATGATCAAGGAGCACACGGCCAAATACAACGAGATCCAGCACGAGTATCTGCGCAAGCGCTCCGTCCTGCAGAAATCTGCCAAACGAGACGGTAAGAAGAGTCCTGAGCACGGGCCGTCGTTCTTCGAGCAGGAGCTTCTTCATCTGGATCAGGACAGCGCACAGAAGCTGGCGGAGCTGAAGgagcagcagcaacagcagctCCTCAACCTGCGACAGGAGCAGTACTACAGCGAGAAATACCTCAAGAAAGAGCACATCAAacagGTGATCGAGAAGCTGACGTGCATCGCGGAGGAGAGTCAGAGTGGTCAGATGAAGAAGATCAAGGAGCTCTGCGAGAAAGAGAAGAAGGAGCTAAAGAAGAAGATGGACAAGAAGAGGCAAGAGAAGATCAGCGAAGCCAAGTCAAAAGAGAAACACCTGACAGAGGAagagaAGCTGGAGATCAACAGGTCGTATGTAAATGAGGTGGTCCAGCACATCAAGAGGTTTCTGTTTCCTCTTGAATATCTTCTTCTTGAATGTCTGCAGCTCCAGAATGACCTGGATCAGGAATACCAGGATAAATTCCGGCGGCTTCCGTTGGAGATCCAGGAGTTTGTGCAGGAAAGCACTAAGAGAAAGACTGAGGATGGAGATGCGGAGATGCTTCCCTCGTCCTCCACACTGGAGAAACTCACACAGTCAGAGGACGACACCGAGGAGGAGAAGAAAGACTGA
>TCONS_00024521
TTAGAGGCTTATTTTCAGGATGTTTGATGGCAGCGAGGATTCATTATTGTCTTCCCTCAGGAAGCAAAGCTCCGGGAGCTCCTGGATGTGGGGAATCTGGTGGGACGGATAGAGAACCGGATGCTGACGGTGGTGACTGGACCCGACATGGTCAACATCCAGTACCTGAACTTCATGGCCTTCCAAGAAGACGTCGCCAAGGAGTGGGCAGATGAGCTGTTTAGTCTGGCCTCAAACCTGCTGGCTCAGAACATGTGCAGAGAGTCCTGTCTGGAGAAAGCCTTCACAAGACTCAAGCTGCAGACAAATCAAGAGGGTCGAATCCCTGTGAAAAATGTTTCCCGCGTGTTCTCCACGGACCGGAAGCGTGTGGAGACAGCGCTGGAGAGCTGTAATCTGCCGTCCGGCCGGGTGAGCATATGTTTGGGATAATCGCTGCAGGATCCCGCCGGCACACAGGAACACCGCGTGTTTCCACAGGAAGCCGATGCACGGCTTTTAGCAacaaaaaaatgtgtgctttCAGATATCAAAGCC
>TCONS_00023427
ATGGCTGGAGCTCAACCTGGCGTTCACGCGCTTCAACTCAAGCCGGTGCGCGTGTCCGAGAGCCTGAAGCGAGGCAGCAGATTCATGAAATGGGATGAG

Function

symbol description
plcb1 Enables several functions, including calmodulin binding activity; phosphatidylinositol phospholipase C activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in cytokine-mediated signaling pathway; phosphatidylinositol metabolic process; and positive regulation of JNK cascade. Located in cytoplasm and nuclear speck. Implicated in developmental and epileptic encephalopathy 12 and myelodysplastic syndrome. Biomarker of Alzheimer's disease; acute myeloid leukemia; and myelodysplastic syndrome.

GO: NA

KEGG: NA

Ensembl:

ensembl_id ENSDARG00000109726

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00023426 False 3021 mRNA 0.49 27 3841012 3986236
TCONS_00024521 False 537 lncRNA 0.53 4 3904680 3912731
TCONS_00023427 True 99 mRNA 0.59 1 3986138 3986236

Neighbor

gene id symbol gene type direction distance location
XLOC_011848 NA coding downstream 11186 3823109 ~ 3829826 (-)
XLOC_011847 PLCB4 coding downstream 25319 3717384 ~ 3815693 (-)
XLOC_011846 WSCD1 coding downstream 537207 3281440 ~ 3303805 (-)
XLOC_011845 tmem151bb coding downstream 650942 3183276 ~ 3190070 (-)
XLOC_011844 NA coding downstream 789916 3020946 ~ 3051096 (-)
XLOC_011850 bmp2a coding upstream 241018 4227254 ~ 4231532 (-)
XLOC_011851 gdf3 coding upstream 253201 4239437 ~ 4252248 (-)
XLOC_011852 napba coding upstream 310840 4297076 ~ 4318428 (-)
XLOC_011853 klhl10a coding upstream 400413 4386649 ~ 4396692 (-)
XLOC_011854 NA coding upstream 1156149 5142385 ~ 5143041 (-)
XLOC_011835 NA non-coding downstream 1404734 2430899 ~ 2436278 (-)
XLOC_011834 CABZ01058452.1 non-coding downstream 1418983 2401258 ~ 2422029 (-)
XLOC_011832 CABZ01052589.1 non-coding downstream 1675242 2165656 ~ 2165770 (-)
XLOC_011855 NA non-coding upstream 1171135 5157371 ~ 5426458 (-)
XLOC_011856 NA non-coding upstream 1466077 5452313 ~ 5564131 (-)
XLOC_011859 NA non-coding upstream 1664875 5651111 ~ 5654012 (-)
XLOC_011864 NA non-coding upstream 1894841 5881077 ~ 5884928 (-)

Expression


Co-expression Network