CI01000299_04186183_04196219 (MX1, MXB, MXA)


Basic Information

Item Value
gene id CI01000299_04186183_04196219
gene name MX1, MXB, MXA
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000299
NCBI id null
chromosome length 6567443
location 4184967 ~ 4197884 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000299_04186183_04196219.mRNA
AATAATGCTTCTTCAACTCTCTCGATGTAATGGGAAATATCTGACATAGAATAAATATTTTAAAAGTTCATTTATAACAATATTTACAACATCTTTCAATGTTCCTGAAAATGTGTTCTGGTCAATAAACACTGGTCAAACAGCCAGGAATACTTACAGTCCTCCGAGGCATTGAGCTGAGCTCGTGCATTCCTTTGAACTTGTGCATTGTTGGTTTTGAGAAGTAGAATGGTCCAAAAGAAAGCACAAAATGAATTAAAACAATACTTTGAAGCAGTTTTGGTAAACAGATAGTATAAACAACTGCTGTGCTTTTTCAGTAACAATTTACAAAAACATCATATTTTGAAATGATGCAGAATACAATATGATGACAGATGAATTCCTGTCCGTTTACACCAGTTTACAGTGTTAAAAATGTACAAAATGCACTTGCCAAGAGCTGTACATGGATTAATTTCAGCTGTTCTAGGGCTTGCAATGGTAGAAATGATCTGGTAGTTTAACTTTTAAATGAATGTATTTTCTTTTTTTCACAAGCAATGATACATACATAATAGGATACAGTATGTAAGGTTATAAACTTTAGAGATGACTTGTTATTCAGCAGACAGTGCTGCTCTGTTCACGCATTATTATGGATAAACACCGCCCTCTACAGGGTATTTCAGAGATATAAAAATCAGCAGAAACAAAGCATGCAGCCTAATAATAATGATTCAATAATCACATTCATAACAATTCACAGTAAAAAAATATATATTTTGAGAATGAACATTATTTATCTATATACATAGCCTAACATTATTAGCCTAGTATTATGTTCAATAACATTGCAAATAATGCATGGCCATAACTTTAAAAAGTAGGTGATGATATGGTAAGATTAGGAGAGTGAGAACAGTGTGTATTTACTGATAAACTGTAATTTAGATGATTGAGTTTATAATCTCAGTCAAAGCTGAATGACCTTATATGAAAATGGATGGATTGTAATGTGTAGGCTATAAAAATATTTAGGCCTATAGCCTACAAGAAATCCTGTGCGTCATAAAGCCATCCATTATGTCACTTTGCTTATCTAAATGTGATGTAAGGTGTACTTTTGCTTTACCCTGGGCTAAAAGCTGTATGTTGACTGTGAAACACAGTAGAATTTAATTATATGAATTTCCCTGACCGCATCCGTGTGCAGTGTGAATGTTCATCTAACCTGTTAACATGGGCACGGAAATAAATAACGGAATATATGCTATATGTGCACCTGGCGTCAAATGCGTTTGTTTGTTTGTACTGTTTCTTATTGTTTATGCTAATTTATCCGGTTGGGCGTGTTCAACGTTTTGCACTTCTGCCCGTAAACATGCAAACAAATGAGTGTTTCCATAATAAAGTTTCTGCTCACTTTGTCAATGAGTGACCGGACTGTACAATAAACCTTAAAATATGATTATTGTACCGTGCTTAAAGGGGCGAAACGAAACTTTTTTGATATCCAGGAAATGAAACTTAGCAACGTACATAAACGCTTTAGGATTCACTTTACGGATAAGAAACAGCATCACTCTGAGACAGTCCTATCGAGGAGTGCACGAACAGACAGCTCCTGATATATCGACGTGAAGTATTTCTCTGATATTTTGACCTTTCTGACGTTGTTTAAGGATGGAGAAAATGAGTTACACGTTCAGTCAGCACTATGAGGAAAAAATCCGCCCTTGCATCGACACTATCGACAATTTACGGTCTTTGGGAGTCGAAAAGGACCTGGCGTTGCCTGCCATCGCCGTCATTGGAGACCAAAGCTCAGGAAAGAGTTCTGTTCTGGAGGCGCTGTCAGGAGTAGCGTTACCCAGGGGTAGTGGAATTGTTACACGATGCCCTCTTGAGCTCAAGATGATAAGAACTAAAGGCGAGGAGAAATGGCATGCGAAAATCAGTTACCAGAACCATGAGGAAGACATTGATGACCCAGCAGAAGTGGAGAAGAAGATTCGTGAAGCCCAGGATGAGATGGCTGGAGCAGGTGTTGGTATTAGTGATGAACTCATCAGTCTGCAGATCACCTCTGCCAATGTTCCTGACCTCACTCTCATCGACCTTCCCGGGATCGCTCGAGTGGCAGTCAAGGGTCAACCTGAGAATATTGGAGATCAGATTAAGAGACTGATCAGGAAGTTTGTTACAAAGCAAGAAACCATTAACCTGGTTGTGGTGCCATGCAATGTTGACATCGCGACCACAGAAGCATTGCAGATGGCTCAGGAGGAGGACCCTGAGGGCGAAAGGACTTTAGGCATCTTAACAAAGCCAGACCTGGTGGATAAAGGCACTGAAGGGACAGTGGTAGACATTGTGCATAATGAGGTCATTCACCTTACTAAAGGATACATGATTGTAAGGTGCAGGGGACAAAAAGAGATTATAGATCATGTCACTCTCAATGAGGCCACAGCAACAGAGAACGCCTTCTTCCAAGACCATCCTCAATTCAGCAAACTCTATGAAGAAGGTTTTGCTACTATTCCTAAGTTGGCTGAGAAACTAACAATTGAGTTGGTTCATCACATTCAGAAATCCCTACCTCGGTTAGAAGAGCAAATCGAGGCGAAGCTCGCAGAAACACAGAAGGAACTGGAGGCGTATGGCAACGGACCCCCATCAGACCCTGTAGAAAGACTGAGCTTTCTCATCGATAAAGTTACATCTTTCACACGTGACACCCTCAACCTGACCACCGGGGAAGAGATTAAATGTGGATCAGATCTACTGATTTTTCCAGAACTACGTGAAGAATTTGCAAAATGGAATGGCTTCTTGGATCATTCAGGATATTTATTCAACAGGAAGATTGAGAAAGAAGTTGACAACTATGAAGCCAAGTATCGGGGAAGAGAGCTTCCAGGATTCATCAATTACAAGACCTTTGAGGGGCTTGTTAGGGATCAGATCAAGATGTTGGAAGAACCTGCCTTAAAAACACTGAAGACCATCTCTGATGTGGTTAGAAAGAAGTTCATCCAACTGGCCCAGTACAGCTTTGTTGGATTCCCCAATCTTCTGAAAATAGCAAAGACTAAGATCGAAGCCATCAAGCTGGATAAAGAATCCCAGGCAGAATCCATGCTGAGGACCCAATTCAAGATGGAGCTCATTGTTTACAGTCAAGACGGCACATATAGCCAGAGCCTGCAACATACAAAGAATAAGTTGGAAGAGGATGAATACACTACAGAAAGTTTTAATTGCATGAGCGTAGGCATTTGCACAGACAATCATGCCACCTTGCGTGAGATGAGGTTGCACCTTGAGTCCTACTACTCGATTGCAAGCAAGCGTCTAGCTGACCAGATCCCAATGGTGATCCGCTATATGTTGCTCCAGGAAGCAGCTTTGGAGCTGCAAAGGAACATGTTGCAGTTGCTGCAAGATAAAGATGATGTAGACAACCTGCTTAAAGAAGACTTTGACATTGGCCAAAAGCGGGAGAGCTTACTGAGTCGTCAGAAACGTCTGATGAAAGCACGCAGCCTCTTGGTTACCTATTAGAATTCACTTCATATAGTCAATTGCAACGGTTTTAATGCAACAAAATCATATGCTCACAAGGTTATAGCTTGACATATTACATTTACATTATTTTGTACATTTAATCATTGAGTTATGAAGTGTCCCCCATATACGCAGTGTGCCAGGAATTTTGGGCATCAGCTGTTATCATGTCATGATTTTATCAACTTCGACTTCTTAGTAAAGCCTGTTTTATCCATGAGCAATTTTGAAACAGCAATCCATGCCTTTGTAACATAGCGTGACTACTGTAATTCACTGTATTATGGCATTTCTCAGGCTTCTATTTAACCGTCTGCAGCTGCTGGACTGATCAAAGGGAAGTCCTTTCTGATATAATTTCTTTGCACTGGCTCCCTGTCAAGTATCAGATCGATTTTAAACTCTTATTATTTGTCTACAAGCCCCTCAATAACCTGGCACCTCAATACTTAACTGATTTATTGCTTCCGTATACCCATTTTTTTTTTTTTTACGGGTGGAGAATATATATATATACAAAGGCGGATTAGAACCCAGAACCTCTGGCACGCTTAACAAAAGTTCTACCGCCAGACCATTAGAACTCACAAACAATTATATGGGATCTATGTGTTATAAAAGCCCATTGTAAATGTACGTTCACTTGTGTCTTTGAGACGTGTGTTGGCGATCAGCCAACGTTAGAGCACGCTGTCATCACTGCAGCGTAAAGACACCACACTATTTCCAGCAGGTGGCACTGATTAGCGTTTTTAGAATATAGTTCTTTATGCAGCGGGTGAAAACCAAACAGACATTATGCTTTCTTCACGTTTGGTATTGTGTGCCTATATAGTATGAAACAAGTAAGTGAATTTATGCACTGTAGTTTATTAATTGTTTTGTTAAGGTGTATGATCCATTTATGAGCATCCTGAATATATATCAATCTTGGTATGTTGATATTTGTTGTTTATGCTTTACATAGTAGTGATTTGATTTGTGTTGTGGACGTGTTCGTATTATATTCTATTATATATATATATATATATATATATATATATATATATGTTTGTTATTTAATTAATTTAATTCTTTGTGTTATGTATTCTATTATTGTTAATTATTTCTATTTTATTCTATGTTTCAGACCACACACACTCAAAAATCAATGTACTTGCACTTATGTACTCAAAGTTTTATTCACACTGTGGAATTATGATGGTGAAATAAA

Function

symbol description
mxa Predicted to enable GTPase activity and microtubule binding activity. Acts upstream of or within response to arsenic-containing substance; response to bacterium; and response to virus. Predicted to be active in several cellular components, including cytoplasm; microtubule; and nucleus. Is expressed in several structures, including digestive system; gill; heart; immune system; and muscle. Human ortholog(s) of this gene implicated in alopecia areata; avian influenza; liver disease; and prostate cancer. Orthologous to human MX1 (MX dynamin like GTPase 1) and MX2 (MX dynamin like GTPase 2).
mxb Predicted to enable GTPase activity and microtubule binding activity. Acts upstream of or within response to virus. Predicted to be active in several cellular components, including cytoplasm; microtubule; and nucleus. Is expressed in head kidney. Human ortholog(s) of this gene implicated in alopecia areata; avian influenza; liver disease; and prostate cancer. Orthologous to human MX1 (MX dynamin like GTPase 1) and MX2 (MX dynamin like GTPase 2).
mx1 Enables identical protein binding activity. Involved in antiviral innate immune response; interleukin-27-mediated signaling pathway; and negative regulation of viral genome replication. Located in cytosol; nuclear membrane; and perinuclear region of cytoplasm. Implicated in alopecia areata; avian influenza; liver disease; and prostate cancer. Biomarker of Human papillomavirus infectious disease.

NR:

description
interferon inducible Mx protein

GO:

id name namespace
GO:0005737 cytoplasm cellular_component

KEGG:

id description
K14754 MX; interferon-induced GTP-binding protein Mx

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000299_04186183_04196219.mRNA True 4765 mRNA 0.39 12 4184967 4197884

Neighbor

gene id symbol gene type direction distance location
CI01000299_04171373_04175441 NA coding downstream 9526 4171149 ~ 4175441 (-)
CI01000299_04158468_04164223 MX2, MX1, MXB, MX, MXA coding downstream 20252 4158001 ~ 4164715 (-)
CI01000299_04136702_04142005 NA coding downstream 42842 4134820 ~ 4142125 (-)
CI01000299_03492360_03492614 NA coding downstream 691823 3492214 ~ 3493144 (-)
CI01000299_03341031_03366645 KLF7, KLF7A, KLF7B coding downstream 818239 3340766 ~ 3366728 (-)
CI01000299_04227918_04239792 EFNB2B coding upstream 29636 4227520 ~ 4239792 (-)
CI01000299_04242809_04251680 ARGLU1 coding upstream 44313 4242197 ~ 4251865 (-)
CI01000299_04370401_04385955 RADIL coding upstream 172517 4370401 ~ 4388020 (-)
CI01000299_04398464_04403711 NA coding upstream 198590 4393404 ~ 4403711 (-)
CI01000299_04456420_04468754 NA coding upstream 258345 4456229 ~ 4469450 (-)
G407296 NA non-coding downstream 5340 4156825 ~ 4179627 (-)
G407318 NA non-coding downstream 55747 4129003 ~ 4129220 (-)
G407288 NA non-coding downstream 57327 4121679 ~ 4127640 (-)
G407306 NA non-coding downstream 118319 4066205 ~ 4066648 (-)
G407303 NA non-coding downstream 135140 4049542 ~ 4049827 (-)
G407330 NA non-coding upstream 9913 4207797 ~ 4208154 (-)
G407340 NA non-coding upstream 61598 4259482 ~ 4263461 (-)
G407343 NA non-coding upstream 68470 4266354 ~ 4266553 (-)
G407344 NA non-coding upstream 69335 4267219 ~ 4267442 (-)
G407348 NA non-coding upstream 74028 4271912 ~ 4272172 (-)
G405053 NA other downstream 2166917 2017687 ~ 2018050 (-)
G404976 NA other downstream 2303979 1855639 ~ 1880988 (-)
G404784 NA other downstream 2524967 1659655 ~ 1660000 (-)
G404372 NA other downstream 3109076 1070607 ~ 1075891 (-)
G407413 NA other upstream 278110 4475994 ~ 4550721 (-)
CI01000299_04913779_04927715 NA other upstream 728084 4913373 ~ 4927715 (-)
CI01000299_05428160_05443433 APP, APPA other upstream 1243453 5427661 ~ 5443433 (-)
G407805 NA other upstream 1629952 5835889 ~ 5835989 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_000976 mxa coding NC_007112.7 CM002885.2 7562316 ~ 7570181 (-)