XLOC_001306 (dis3)


Basic Information

Item Value
gene id XLOC_001306
gene name dis3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 30736449 ~ 30762264 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00002138
CACTGTGTGCTGTGTTTTGGTGGAACAGCTCTTCAAAACCGCTTGACCATTAGCTTGACCATGTTGAAGtccaaaacatttgtaaaaaagaCCCGTTCTGGCGGAGTGTTGAAAATCGTACGGGAACATTATCTCCGAGATGACATCTGGTGTGGAAGTGAAGTTTGTAAGGAGTGCAAAGATGAAGCTCCGGTGCTGCAAGAAGAAACTTGTATAGAAAGCAACCTCTGCCCATATCCTCACTATTTAATCCCAGACACCAATGTGGTTTTAcatcagATCGATATCCTTGAGGACCCTCTGATCAGGAACGTCATTATTCTTCAGACCGTTTTACAAGAGGTCAGACACAGGAGTGCACCAGTTTACAAAAGAATCAAGGATGCTATTCACGAAAAGGAAAAGCACTTTTACACCTTTACAAATGAGCACCACAGggaGACATTTATTGAGCGAGAGCAAGGTGAAAGTGCTAATGATCGCAATGATCGAGCCATCCGTGTCGCTGCTAAATGGTACACTGATCACCTTGCTAAGGCAACTGATGGCGGGACACTGAAAGTGGTTCTGTTGACCAATGACCGGGCCAATAAAGAAAAGGCAGAGCAGTTTGGTCTTACTGTGTACAGATGTGAAGAGTATATCAAGAGTTTGGTTGGCAACCCTGAGCTTGTGGACAGGCTTGCAATGACATCTGATGATCAAAATGAAATCACtggcagtaagttactctttccAGAGCACCTGCCCTTATCCAGGATTCAGACTGGCATCAAGAATGGAGTATTCATTCAGGGTACATTTCATGCCAACCGTGATAACTATCTGGAGGGGACAGTCTTTGTAAATAGAGAGGGGGAGGATATCAATGAGATTCTACTTCAAGGCCTTCAGAATTTAAACCGGGCTGTGAATCAAGATGTAGTGGCTGTTGAACTCTTTCCAAAAGACCGCTGGGTTGCTCCATCATCTGTCGTCCTTCAGGatgataatttaaatgatgaagatACTGAAGAAGATGAGAATGACAGTAAATTGAAGAGTGTAGCATCAGAGTCTAGTGTCCTAAAACCCACAGGAAGAGTGGTGGGCATCATAAAGAGGAACTGGAGGCCTTTCTGTGGGATGCTTGCACAGTCACAGATCAAAGAGGCAACAAGACACCTTTTCACTCCAGCAGACCGGAGAATCCCACGAATCCGCATTGAAACCAGACAAGCTGCCACACTGATTGGACAGAGGATTATGGTTGCTATAGATGGATGGCCTAAAAACTCAAGATACCCAAACGGTCACTTTGTGAAAAACCTTGGCACTGCTGGAGATAAAGAGACAGAGACCGAGGTGCTTCTTCTAGAGCATGATGTTCCTCACCAACCCTTCTCTCAGGCTGTTCTCAGTTTCCTTCCCAAGATGCCCTGGGGTATTACAGAGGAGGACCTGAAGGTCAGGGCAGATCTCAGACATCTCTGTGTGTGCAGTGTGGATCCTCCTGGATGTACAGATATTGATGATGCTCTTCACTGCCGGGAACTGGAGAATGGAAATTTGGAGGTTGGTGTTCACATAGCAGATGTCAGCCATTTTATTCGGCCAGGGAATGCACTAGACCAAGAGGCTGCAAACAGAGGCACCACAGTTTACCTTTGTGGAAAGAGAATAGACATGGTTCCTGAACTTCTGAGTTCCAACTTGTGCTCACTGCGGTCCAACGTTGAGAGGTTGGCATTCTCTTGTATTTGGGAGATGAATCATAAGGCTGAAATCATCAAAACTCACTTTACAAAGAGTGTCATTAACTcaaaggCCTCACTTACATATGCAGAAGCTCAGATGAGGATTGATGACACCACCATGAATGACGACATCACAAAGAGCCTTCGGGGCCTTAACAAATTGGCTAAGATCTTAAAGGCCCAGAGAATTGACAAAGGAGCGCTGACACTCTCATCTCCTGAAGTACGCTTCCACATTGACAGCGAAACGCATGACCCTATAGATCTGCAGACCAAAGAACTAATGGAGACTAACTCTATGGTAGAGGAGTTCATGTTGTTGGCGAATATCTCAGTAGCTCAGAAGATCTATGATGAGTTCTCAGAATGTGCTCTGCTGAGGAAACATCCTGCACCGCCACCGTCAAACTACGACATCCTCATCAAGGCTGCAAAGTCCAGGGATCTGGAGATCCACACAGATTCCGCCAAAGCTCTGGCCGATTCCCTAAACAATGCAACGATTGAGAACTTTGCATATTTCAACACTCTTCTGAGGATTCTGGCCACCCGCTGCATGATGCAGGCTGTGTATTTCTGCTCTGGCATGGACAGTGATTTCCACCACTATGGCCTGGCATCACCTATTTACACACACTTCACCTCACCCATCAGAAGATACGCTGATATCATCGTTCACCGTCTGTTAGCAGTGGCTATTAATGCAGACAGCACATACCCTGATTTGATGGACAAGCATAAGCAGTCGGCCTTATGCAACAACATCAACTACAGACATAAAATGGCCCAATACGCACAGAGAGCCTCAGTGGCCTTCCACACTCAGCTGTTTTTCAAGAATAAGGGAATCATAAATGAAGAAGGCTTTATTCTGTTTGTGAGAAAAAATgccatcatcatcctcatccctAAATTTGGTTTGGAGGGGACCGTGTTCTTTGAGAACAAGGACAAACCCAGTCCTCGTCTCAGCTTTGACACGGAGggtCCTACGCTTAAAGTGGAAGAACACACTTTCCGCATCTTTGATCGAGTCAAAGTCACAATTAGTCTTGATGCTTCCAACTTGCAGCACCAAAGGATCAGAATGGCGCTCACTGAGCCTGtgatCCCTGGTGTCAGTGTACCCATCCCTGAATCAGAACCAGAGGCCAAAAAACCCAAGCTTGACCGTTGATATACGAGCATTTAAAGCTATCATACTACTTTATATAAATGCTAACTTTTGCTTTCAGCTCATCTACAAGGTAGTTTCATGAAGACCTTGAGTTAACACCTAAAGCAGTAAAATGGACACAAATgggtttttaatagttttttttataattattgaatGCATCCTGTACTGTTTTTGCTCTTGATtctcttctctctcttttttttttttactaatacacAATTTTTATCTGTTAGAAACGATCAATAGCACTGGATCAACAGTGAGGAGTCTTTCTGTTGGTTTCATTGTCATTGAAAACAGAACATCAATATTAAACAGACTTTTGAAGAAA
>TCONS_00002139
TGTGTTTTGGTGGAACAGCTCTTCAAAACCGCTTGACCATTAGCTTGACCATGTTGAAGtccaaaacatttgtaaaaaagaCCCGTTCTGGCGGAGTGTTGAAAATCGTACGGGAACATTATCTCCGAGATGACATCTGGTGTGGAAGTGAAGTTTGTAAGGAGTGCAAAGATGAAGCTCCGGTGCTGCAAGAAGAAACTTGTATAGAAAGCAACCTCTGCCCATATCCTCACTATTTAATCCCAGACACCAATGTGGTTTTAcatcagATCGATATCCTTGAGGACCCTCTGATCAGGAACGTCATTATTCTTCAGACCGTTTTACAAGAGGTCAGACACAGGAGTGCACCAGTTTACAAAAGAATCAAGGATGCTATTCACGAAAAGGAAAAGCACTTTTACACCTTTACAAATGAGCACCACAGggaGACATTTATTGAGCGAGAGCAAGGTGAAAGTGCTAATGATCGCAATGATCGAGCCATCCTGTACCCATCCCTGAATCAGAACCAGAGGCCAAAAAACCCAAGCTTGACCGTTGATATACGAGCATTTAAAGCTATCATACTACTTTATATAAATGCTAACTTTTGCTTTCAGCTCATCTACAAGGTAGTTTCATGAAGACCTTGAGTTAACACCTAAAGCAGTAAAATGGACACAAATgggtttttaatagttttttttataattattgaatGCATCCTGTACTGTTTTTGCTCTTGATtctcttctctctcttttttttttttact

Function

symbol description
dis3 Predicted to enable 3'-5'-exoribonuclease activity and endonuclease activity. Predicted to be involved in rRNA catabolic process. Predicted to be located in nucleus. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Orthologous to human DIS3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease).

GO:

id name namespace
GO:0016075 rRNA catabolic process biological_process
GO:0000176 nuclear exosome (RNase complex) cellular_component
GO:0000177 cytoplasmic exosome (RNase complex) cellular_component
GO:0000178 exosome (RNase complex) cellular_component
GO:0004519 endonuclease activity molecular_function
GO:0004540 ribonuclease activity molecular_function
GO:0003723 RNA binding molecular_function
GO:0000175 3'-5'-exoribonuclease activity molecular_function

KEGG:

id description
ko03018 RNA degradation
ko03019 Messenger RNA biogenesis

ZFIN:

id description
ZDB-GENE-080213-3 Predicted to enable 3'-5'-exoribonuclease activity and endonuclease activity. Predicted to be involved in rRNA catabolic process. Predicted to be located in nucleus. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Orthologous to human DIS3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease).

Ensembl:

ensembl_id ENSDARG00000060559

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00002138 False 3247 mRNA 0.44 21 30736449 30762264
TCONS_00002139 True 757 processed_transcript 0.40 4 30736570 30762254

Neighbor

gene id symbol gene type direction distance location
XLOC_001305 MZT1 coding downstream 13191 30718246 ~ 30723258 (-)
XLOC_001304 dachc coding downstream 47445 30585140 ~ 30689004 (-)
XLOC_001303 ubac2 coding downstream 168224 30539971 ~ 30568225 (-)
XLOC_001302 igf2bp2b coding downstream 225492 30443193 ~ 30510957 (-)
XLOC_001301 CR382370.2 coding downstream 295389 30439422 ~ 30441060 (-)
XLOC_001307 NA coding upstream 66092 30828356 ~ 30842747 (-)
XLOC_001308 NA coding upstream 76299 30838563 ~ 30878846 (-)
XLOC_001309 BX548015.1 coding upstream 157072 30919336 ~ 30923141 (-)
XLOC_001310 dlx2b coding upstream 215672 30977936 ~ 30979707 (-)
XLOC_001311 ppp1r9alb coding upstream 309444 31071708 ~ 31105376 (-)
XLOC_001299 CR382370.1 non-coding downstream 401620 30333202 ~ 30334829 (-)
XLOC_001298 BX255890.1 non-coding downstream 491804 30244531 ~ 30244645 (-)
XLOC_001294 NA non-coding downstream 1077672 29653949 ~ 29658777 (-)
XLOC_001292 BX908780.4 non-coding downstream 1409501 29323374 ~ 29326948 (-)
XLOC_001313 BX284697.2 non-coding upstream 526272 31288536 ~ 31296246 (-)
XLOC_001317 NA non-coding upstream 836054 31598318 ~ 31600848 (-)

Expression


Co-expression Network