CI01180000_00661446_00671602 (MSH6)


Basic Information

Item Value
gene id CI01180000_00661446_00671602
gene name MSH6
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01180000
NCBI id null
chromosome length 11503085
location 661109 ~ 672188 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01180000_00661446_00671602.mRNA
CATATAAAAACAATGATATATATTCTAACATATTCTAAAAGTATTAATACATATACGCGTTCTAAATGAAAAAAAAAAAAAAAAAAACGCATGTCATATCAGCCACGTGGGTAGTGTAAAAGGATACACAGAGGCTCCTATTGGTCCATATTCTCGCGGCGTCACATGACCCTCCTCTTCCCTTTCCGTGTGCCACCAGCAGCAGCATTTTCCCGCGAACTCTCAGCTCCACATCAACTCAGCTGAGCTGGACAGTTCTGGGTCTGTTGGAATGGAATACATATGAATTCATTTTTTGCATAATTGAACTCCATATTGCACAACACCCTTTGGGAAACATGGCGAAGCAAAGTTCCCTTTTTAACTTCTTCACCAAGTCGCCGCCTCTGGCAGTGAAGGCCAAATCAAACCCTTCTCCAGTGGAGGCAGATGCAGTGAGCAGATCCAACACCTCACCTAAAGAAGAAGCCAAAGTCAACAGCAAGAAAACACCATCAAAACCTGTCAAATCTCAAGCTAAAGCTGGACATGCGAAACTGTTCGGAGAGAAAGCAGACACTGCAAAGGAGAGAGAACAGTCATCCATGTTTAGTGCTGGCACTCTGGTATGGGCCAAGATGGAAGGACATCCCTGGTGGCCCTGTATGGTTGTTCCTCAACCTCTCACCGGACAGCAGATGAGGGGCCGTGGCCGAGACCAAAGGCTTCACGTTCACTTTTTCGATGAACCGCCAACCCGTGGTTGGGTTAACACAAAATACATAAGAGAGTACCAAGGCTCTGATAGCACAGATGCCAAATCCGGAGGCATGTTCTTCAGCGGTAAGCCTGTTATACGTAAAGCAATGGAGCTGGCAGATGCTGCAATGAAGCAGAGTCCTGAGCAGAGACTGAAGATGTCCGTGTGCATGGATCCCTCAGATGAAGAAGAGGAGAATGATGAGGATATGGAGGTTGAGAAATCAACCATATCGGATGTGGAAATGTCTGAGGAAGAGGCTGAAGAAAAGAAGAAGCCCAGCCGACGTTCATCTCGTGCTGCAGCTGAAAAGAGTCAGAAGTCGAAGCGTCGGCGCATTGTGGTGGCATCTGACAGCGATGACTCCGTGAGTAGCGGGGCTGAGGAAGAAGAAAGCGAGCCGGAGCCCGAACCAGACAGCCCTGTGAAACCGGTCAAGCGCAAACGTCCTTTAGAGAAGCCTGCTAAATCAAAGAGCAAACCAGATACCCCAAAACGAGCACCTGCAACTCTTCCATCCGTGGCGTCCAACACTAAGTCTCGACTCTCTGCTTTCTCCGCCCCGGATAACTTCGAAAGTCAGAGTAGCAGTGCAAATGGGACAGATGGAGGATCTACTGTGTGGGACCATGAGAAACTCGACTGGCTGCAGGACGGCAAGAGAAAGGACGCACAGCGTAAACGCCAATCTGACGAAAACTACGACCCCACGACTCTATACGTTCCTGATGATTTCCTGAACAGGACGACGCCTGGAATGCGCCGTTGGTGGCAGCTGAAGTCTGAGATGTTCGATACTGTTCTGTTCTACAAAGTTGGAAAGTTCTACGAGCTCTACCATATGGACGCAGTGATTGGCGTCAACGAACTCGGCCTTACCTTCATGAAGGGTACTTGGGCCCATTCTGGCTTCCCCGAGATTGGCTTTGGACGCTTCTCAGACGTACTTGTGCAAAAGGGCTACAAAGTAGCTCGTGTGGAACAGACCGAGACCCCTGAGATGATGGAAGCACGATGCAAAACATTGGCGCGTCCCACCAAATTTGACCGCGTCGTCAAGCGAGAGGTTTGCCGAATCATCACGCGAGGGACACAGACGTACAGCGTGCTTGACGGCGCCCCTTCTGAAACTCAAAGTAAATATCTGTTGAGCATTAAGGAGAAGAGCGAGGAGGACAGCGCAGGCCATGGCCACATCTACGGGGTCTGTTTCATTGACACCTCGGTGGGACGCTTCCATGTCGGTCAATTCCAGGATGACCGCCACTGTTCCCGGTTGCGTACCCTGGTGGCACACTATTCTCCAGCCCAGGTTCTTTTCGAGAAGGGCAATCCGTCAGCTGAGACGTTGAAAATCTTTAAGGCCCTCTTGTCATCCACTTTACAAGAAGGCCTCAATGCTGGTTCACAGTTTTGGGATGCCCAGAAGACCCTAAAGGTCCTTGCTGAGGAAGACTACTTCAAAGAAAGCAAAGCGTCAACTGATGATGAAAAGGGATCAGTGCTGCCTCCAACTCTCAAAGCTATGACGTCCGAATGTGACGCTCTAAGTCTCACTCCAAAGACGGGTTATGAACTCGCTCTTTCGGCCCTTGGTGGCTGTATGTTCTACCTAAAGAAATGTCTAGTGGACCAGGAGCTTCTTTCCATGGGCAACTTCGAGGAGTATGTTCCTGTCGACGTGGAGATGGAGCAGGCTGGAGGAGCGTCTTGTTTCTTTGCCCAGACCCGTCAAAGAATGGTTTTGGATGGAGTGACCCTTGCTAACCTTGAGATCCTTCAGAATAGCTCGACCGGTGGTCTTGAGGGAACCCTACTTGAACGATTGGACACGTGTTGCACTCCCTTCGGCAAAAGGTTGTTGAAGCAATGGCTCTGCGCCCCTCTTTGTAATCCATCCTCCATTAGTGACCGCTTAGATGCTCTGGAGGACCTGATGGGCGCTCCGTCCCAAGCGACCGAAGTCACCGACCTACTAAAGAAGCTTCCGGATCTCGAAAGGCTACTTAGCAAGATTCACAGCATGGGTACTCCTTTAAAAGGACAGGACCACCCGGACTCCCGAGCAATTCTGTACGAGGAGGTTGTCTACAGCAAACGTAAGATCGCTGACTTTCTCGCAGCACTTGAGGGATTCAAAGTTATGAAAGAAATCGTGTCGATCATGGAGCCCGTCGCTGAAGGCTTCCGATCGAAACTGATGCGCCAAGTGGTGCTCCTCAAGACAGAAAACGAAGATGGGCTTTTCCCCGACCTCTCGCCAGAGCTCAAACGTTGGGACACTGCTTTCGACCATCAGAAAGCTCGCACCACAGGTGTCATAACTCCAAAAGCTGGCTTTGATCCGGAGTACGACCAAGCCCTAAACGGAATTAAAGACTGCGAGAGAGGCCTGCAGGAATACCTGGACAGACAGAAGAAGAGATTGGGCTGTAAGAATCTATCCTACTGGGGAACTGGAAGGAACCGCTACCAGCTCGAAGTTCCAGATAGTGTTTCCGAGAGGAGCGTGCCAGAGGAGTACGAGGTGAGGTCCACTAAGAAGGGCTGGAAGCGGTACTCTACCAAAGAGATCGAGCAGCTGTTTTCAGAGATACAGAGCTGGGAAGACAAAAGAGATGCAGCGCTGAAGGATTGCATGAGAAGACTCTTCTACAATTTCGACAAGAATTACAAAGACTGGCAGACAGCTGTTGAGTGCATGGCAGTACTTGATGTGCTGTTGAGCATGTCCCGGTACAGTCAGAGCGGCGACGGGCCCATGGTGAGACCAGAGATGGTTCTTCCGGGTGACGGGTCTCAGTCGCCCCCCTTCCTGGATCTGAGAGGGTCCCGTCACCCTTGTGTCACCAAGACCTTCTTTGGTGATGACTTCATTCCCAATGACATCTTCATCGCTTGCCCTAGCGGTGAAGAAGAAGAGGGTCAAGATAATGGTAAAGCACTTGCCCCATGTGTGTTAGTCACCGGGCCAAACATGGGAGGCAAGTCCACCCTAATGAGACAGTGTGGTCTGGTGGTGATCTTGGCCCAGCTGGGCTGTTACGTGCCTGCTGAGAGTTTGCGTCTCACTCCCGTGGACCGAGTGTTCACTCGTCTTGGCGCGTCTGATCGTATAATGTCAGGTGAAAGTACGTTCTTTGTGGAGCTCAGCGAGACTGCTAGCATACTTTTGCACGCCACCAACCACTCCCTTGTCCTGCTTGATGAACTGGGTAAATTATCTGTTCATCTCACAGTAATCAAAGGCAGAGGTACGGCCACGTATGACGGCACAGCCATTGCGAGCGCAGTGGTGAAGGAGCTGTCGGAGAAGATCTGCTGCCGTACCCTGTTTTCCACTCATTACCACTCTCTGGTGGAGGACCACGTCCAGGACCCCGCTGTGAGACTCGGACACATGGCCTGTATGGTGGAGAATGAATGCGAGGACCCCAGTCAGGAGACCATCACTTTCCTCTACAAGTTCATCGGTGGCGCGTGTCCCAAAAGTTATGGCTTCAACGCAGCCCGCTTGGCAAACATCCCGGAGGAAGTCATCCAGTCCGGACATAAGAAGGCCCATGAGTTTGAGAGGAGCACCGTGTCTCTCAGGATATTCAAGTAAGACACTTTATGAACAGTGTTCAGATTGGACCATTTTGCGTTGTGACGTTTTCATGACGATTAAGCACATTTTCCTCCAAAATGATCAATATAATCTGTTTGGGCACACTTCATTAAAGCTGCTGTCCATAACTTTTTTTAGTTAAAAAATGATCCAAAATCAATTATTAAGCAAGTACATAACCAATCAGTGCTCATCTTCTTACCTTAACCTGATTCACAACGGTAAGCTTGTAATAATGTTTTCTAATTTTCGTGGTTCGGGTCGGTTTCTGTGGGAAATACGAGTTTGCCTTTGTTCGTTTTTGCGTCATTAATGTCTGGATAAAGGAGTCCCGTCTAGTAGGCTATATCGCGTGTGTGGCTGGAATAATTAAATTTGTCATTTTGATGGTGACCTGTAATCAAGAAAGTTCAAAACGAAAGTCATCACTAACAACTTGTGAATCACCAGCAGTAAGACTTCAGAGTGACTGAAATTAGATTACATACGTGGGATTACACGGTACTTACAAAATATTTGTATTTCAACGAGCTCTAACGAACATTTAATTGCTTTTTGAGGTTAAACGAACAATATCTTTCA

Function

symbol description
msh6 Enables guanine/thymine mispair binding activity. Acts upstream of or within maintenance of DNA repeat elements. Predicted to be part of MutSalpha complex. Is expressed in several structures, including central nervous system; immature eye; neural tube; optic primordium; and ventral mesoderm. Human ortholog(s) of this gene implicated in Lynch syndrome; colorectal carcinoma; endometrial cancer; hereditary nonpolyposis colorectal cancer type 5; and mismatch repair cancer syndrome. Orthologous to human MSH6 (mutS homolog 6).

GO:

id name namespace
GO:0003690 double-stranded DNA binding molecular_function

KEGG:

id description
K08737 MSH6; DNA mismatch repair protein MSH6

RNA

RNA id representative length rna type GC content exon number start site end site
CI01180000_00661446_00671602.mRNA True 4931 mRNA 0.49 10 661109 672188

Neighbor

gene id symbol gene type direction distance location
CI01180000_00427700_00437883 NA coding upstream 222643 427650 ~ 438466 (+)
CI01180000_00368639_00375465 ZC3H6 coding upstream 284862 368639 ~ 376247 (+)
CI01180000_00361420_00364335 NA coding upstream 295983 361420 ~ 365126 (+)
CI01180000_00306160_00314770 NA coding upstream 345365 306160 ~ 315744 (+)
CI01180000_00263000_00297934 MERTK coding upstream 362643 263000 ~ 298466 (+)
CI01180000_00737754_00743866 NA coding downstream 63122 735310 ~ 744211 (+)
CI01180000_00765917_00776252 NA coding downstream 93609 765797 ~ 776911 (+)
CI01180000_00812535_00858607 NA coding downstream 139669 811857 ~ 859005 (+)
CI01180000_00862066_00867985 NA coding downstream 188558 860746 ~ 868112 (+)
CI01180000_00947514_00949868 NA coding downstream 274233 946421 ~ 950906 (+)
G678595 NA non-coding upstream 109935 503871 ~ 551174 (+)
G678608 NA non-coding upstream 127461 533150 ~ 533648 (+)
G678442 NA non-coding upstream 168478 445739 ~ 492631 (+)
G678554 NA non-coding upstream 173966 434733 ~ 487143 (+)
G678521 NA non-coding upstream 216527 351957 ~ 444582 (+)
G678632 NA non-coding downstream 5686 677874 ~ 685043 (+)
G678703 NA non-coding downstream 26487 698675 ~ 699054 (+)
G678654 NA non-coding downstream 42246 714434 ~ 714846 (+)
G678712 NA non-coding downstream 49935 722123 ~ 722457 (+)
G678640 NA non-coding downstream 75077 747265 ~ 777004 (+)
G678440 NA other upstream 509457 147934 ~ 151652 (+)
G678751 NA other downstream 387655 1059843 ~ 1066091 (+)
G678637 NA other downstream 477363 1149551 ~ 1155672 (+)
G678946 NA other downstream 846165 1518353 ~ 1612547 (+)
G679076 NA other downstream 1122982 1795170 ~ 1799433 (+)
G679324 NA other downstream 1716679 2388867 ~ 2397360 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location