XLOC_015050 (angpt1)


Basic Information

Item Value
gene id XLOC_015050
gene name angpt1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007130.7
NCBI id CM002903.2
chromosome length 48449771
location 46812272 ~ 46957968 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00029638
GACGGGATCAACAATGCGTCCGGACGTGATCCCCACGTGTCCGTCCCAGCATCCGCACTCAATCTGATCCAACATTTTAGTTAGTTCTTGATATATTTGTGAGTTTTCCGTCCCATCGGGCTCCTGCCATGTGGTGGGGTTGCTTGTTTCTGGCAGCGCTGCTGGTGGTTGCAGATTGTGGAGGAGTTGAGCAGAAAACAGACGGACTCAGGAGCTCCACGCCGAAATCCAACAGCAGCAGCGGTCGGAGGTATCACCGGATCCAGCATGGACAGTGCAGCTACACGTTTATCCTCCCGGAGAGCGATGGAAACACTTGTCGAGAGTTTAAATCGGGCACGGCGTACAATGCCAATGCATTACAGCGGGACGCTCCTCAACCCGAAGCCGACTTGTCCAACCAGAAGATCCAGCAGCTGGAGCACGTCATGGAGAACTACACGCAGTGGCTACAGAAGATTGAGAACTACATCAAAGACAACATGAAGACGGAGATGGTGCAGCTACAACAGAGCGCCGTCCACAACCACACGGCAGCCATGCTGGAAATGGGCACCAGTCTTCTGTCCCAAACGGCAGAACAGACGCGAAAACTGACCGACGTGGAGACCCAGGTTTTGAATCAGACGTCGCGGTTGGAAATTCAGCTGCTGGAGAACTCGCTGTCCACCAATAAGCTGGAGAAGCAGCTCATGATACAGATCAATGAAATCAACAAGATTCATGACAAGAATGGGTTTCTGGAGGAAAAGATGCAGGAGCTGGAGGATCGGCACCGGCAGGAGCTGGAGTCTCTGCGGACGGAGAAATCTGACCTGCAGGCTCTGGTCAGCAGACAGAGTTCAGTGATCCGCGAGCTGGAGAATCAGCTGAGCAGAGCTACCGGAAACAGCACAGCACTTCAGAGACAGCAGCAGGACCTGATGGAGAGCATGCGCAGCCTCCTCAGCCTCTGTGCTAAAGACGCCTCTACAGCAGtggtACCGAACAGCACCAAGCAGGCTGACGAGGAGCGAAAGTTTCGGGATTGTGCTGATCTTTATCAAGCAGGCTTCCAGAAAAACGGAGTTTACACCATCAATATTAGCCCACAAGAGACCAAAAagGTGTACTGTGTGATGGAGTCTGCTGGCGGAGGCTGGACGGTGATCCAGAAGCGTGAAGACGGCACTGTGGATTTCCAGAAAACATGGAAAGAATATAAGATGGGTTTTGGAAGCGTGTCGGGCGAACACTGGCTGGGGAACGAATTTGTCCAcgttctgaccaatcagaggcaGCACGGCCTCCGCGTGGAGCTGAGTGACTGGGACGGACACCAGGCCTTCTCTCAGTACGACAGCTTCCACATCGACAGCGAGAAACAGAAATACAGGTTGTTTTTGAAGACCCACAGCGGGACGGCGGGACGGCAGAGCAGTTTGGCCATCCACGGAGCAGACTTCAGCACCAAAGACGTGGATAATGATAACTGCACATGCAAGTGTGCACTGATGCTCAGCGGCGgCTGGTGGTACGACGCCTGCGGGCCATCCAACCTGAACGGTGTGTATTACAGACAAGGACAGCATGTCGGAAAATTTAATGGAATCAAATGGCACTATTTCAAAGGGCCCAGTTACTCTCTGCGCTCCACCGTCATGATGATCCGACCAGCCGACTTCTCATAGTCCTCTTCAAAATATTGCCAGAAGCGCTGCATTCATGCACAAGACTTTTTCAGTGTACGTGCTTTGCAGCTCCGGCATGCAAATAATGCAGCATTGTTTGGTGATAGCAGGAATCCTGTGAAAAAGAGGCTGTGCTGTCACCTTCCAGGGCCTGAATGGGAATCGGCACGCGTCCCAgagcttttatttttacatatcaGAGGTATGAATTGAAGTGCATTCACTTGTCACTCAGGACTGTTAATTCAGCACTTCAGCAAGTGAACTCAGCAGACATGCGCACTTCTAAGGGAACTTAAAGCAGCTTGAATGCCCTCCAATAACCTAAAGGGACCTATTAATGTTGAATACAAACGTGTTGCACAGATATATTTGTGTTGTGATACTTCAgttcacatttttttattctattttgtaCATTAATCCTGTCAAAGACGTGAAGAGACCCGTTGCATGCAGAATTAAAGGTGACTTTCAGTGCTATTTAcaagaaa

Function

symbol description
angpt1 Predicted to enable receptor tyrosine kinase binding activity. Acts upstream of or within blood vessel development and brain development. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including brain; cardiovascular system; hypochord; medial longitudinal fasciculus; and ventral mesenchyme. Human ortholog(s) of this gene implicated in brain ischemia; diabetic retinopathy; and hypertension. Orthologous to human ANGPT1 (angiopoietin 1).

GO:

id name namespace
GO:0001525 angiogenesis biological_process
GO:0001568 blood vessel development biological_process
GO:0048014 Tie signaling pathway biological_process
GO:0007420 brain development biological_process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway biological_process
GO:0062023 collagen-containing extracellular matrix cellular_component
GO:0005615 extracellular space cellular_component
GO:0030971 receptor tyrosine kinase binding molecular_function
GO:0005102 signaling receptor binding molecular_function

KEGG:

id description
ko04010 MAPK signaling pathway
ko04014 Ras signaling pathway
ko04015 Rap1 signaling pathway
ko04066 HIF-1 signaling pathway
ko04151 PI3K-Akt signaling pathway
ko05323 Rheumatoid arthritis
ko04052 Cytokines and growth factors

ZFIN:

id description
ZDB-GENE-010817-1 Predicted to enable receptor tyrosine kinase binding activity. Acts upstream of or within blood vessel development and brain development. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including brain; cardiovascular system; hypochord; medial longitudinal fasciculus; and ventral mesenchyme. Human ortholog(s) of this gene implicated in brain ischemia; diabetic retinopathy; and hypertension. Orthologous to human ANGPT1 (angiopoietin 1).

Ensembl:

ensembl_id ENSDARG00000030364

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00029638 True 2164 mRNA 0.51 9 46812272 46957968

Neighbor

gene id symbol gene type direction distance location
XLOC_015049 abrab coding downstream 34309 46768266 ~ 46777963 (-)
XLOC_015048 SAMD12 coding downstream 47911 46724211 ~ 46764361 (-)
XLOC_015046 ext1b coding downstream 245842 46421349 ~ 46566430 (-)
XLOC_015047 NA coding downstream 320239 46491583 ~ 46492033 (-)
XLOC_015045 NA coding downstream 391714 46412613 ~ 46420558 (-)
XLOC_015051 NA coding upstream 41293 46999261 ~ 47173408 (-)
XLOC_015052 sdc2 coding upstream 233037 47191005 ~ 47276297 (-)
XLOC_015053 CU138512.2 coding upstream 327805 47285773 ~ 47323267 (-)
XLOC_015054 CU929178.2 coding upstream 442221 47400189 ~ 47400307 (-)
XLOC_015055 CU929178.1 coding upstream 457622 47415590 ~ 47416405 (-)
XLOC_014711 CR382300.3 misc downstream 27083517 19728690 ~ 19728755 (-)
XLOC_015038 NA non-coding downstream 1121857 45689237 ~ 45690415 (-)
XLOC_015036 FP340497.1 non-coding downstream 1567564 45157502 ~ 45244708 (-)
XLOC_015035 NA non-coding downstream 1805215 45003801 ~ 45007057 (-)
XLOC_015061 CU695215.1 non-coding upstream 609745 47567713 ~ 47567848 (-)
XLOC_015063 NA non-coding upstream 802929 47760897 ~ 47761491 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000097_00115317_00182129 ANGPT1 coding CI01000097 null 115317 ~ 182129 (-)