XLOC_017187 (enpp1)


Basic Information

Item Value
gene id XLOC_017187
gene name enpp1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 13403281 ~ 13521010 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00034242
GAGTCCGAGCTCAACAAACCTGTGCAAGGCAAAGCGAGCGCGCGGTCAATAATGGACTCAGCCAAGCGGGATGAACACATGAGCGAACACGCCGCCAACCTACTGGGCACAGGACAGCGGTACACACGGACACACAACACTGCAAAAGTCCAGTCAAGATACTTGAAAATCCTCTGTGCGgtGCTTCTTCTTGGCTTGCTGGCTTTAATACTCACAATCATATTTTTACTGAAACTCCGCTGCAGTGATAAAGTCATTGACAGCTGTAAAAATAGATGCATATCCAAAAGTCATGATGGTAATGCAGGGTGTCGCTGCGATGCTGCTTGCGTAAATGAAGGCACCTGCTGTCTGGACTATGAGGAAGTGTGTTTGCAACCAACTCAGCTCTGGACGTGCTCGAAATTCCGCTGCGGTGAGGACCGTTTGCCCAGCAGCCTCTGCTCCTGCTCTGCAGACTGTGTGAAAGTGGGAGACTGCTGTGCAAACTATAAGAGGACATGTGAAGGTGAAAAGAGTTGGCTTCAAGAGGACTGTGAGGACATCAGGACTCCTCAGTGTCCCGCTGGGTTTTCTAAATCGCCGCTGCTGTTGGTATCTCTGGATGGATTCAGGGCAGGATACATGAATGCATACAGCGCTCTGCTTCCAGCCATCAGGAAACTCAGAGAATGTGGTACCTCCACCCCATATATGCGACCTGCTTATCCCACTAAGACCTTCCCGAATCATTACACCATAGTGACAggTCTCTATCCAGAAACACATGGAATTGTGGACAATAAGATGTATGATGTCAATCGCAATGCTTCATTCAGTTTAAAGGTTGATGAGAAATTCAATCCTTTGTGGTACCAAGGTGAACCAGTAagtaaatctaaaaaataaaattacttttttgcgttttattcacattttaattgTAAGATTTGGGTATTTGtcaaaaatgtttctaaaatttaaaattgtacaaaaatTGCACATAAATTGTCAAATTAGTCTTATTTAAAGAAAACAACCAAATTGTTTTTTAGCACTGAGCCTCAACTCTCCTTTTCATAGCACTTATATATGTTAGAGTTTAAgtgatatttacattttttaagagtagggttagggttagggttagctCTTGTCCATGCAGTTCATGCAGCTTGTTCATGCAGCTCTTGTTCATGCATAATGTGATTGACTAtctcactttaataaaaaaaataaaataaataaaaataaaactttttttattttctggctgtttgcaatattttgtagATTATagagttataaaaataaatttggctattttaacatattctgcagccctacatgtaatttatttgttttagcagtcatttacattatatgaCATAAAATATGTCACATGAATAAAACACCACTTTTCAGAA
>TCONS_00034243
CCGAGCTCAACAAACCTGTGCAAGGCAAAGCGAGCGCGCGGTCAATAATGGACTCAGCCAAGCGGGATGAACACATGAGCGAACACGCCGCCAACCTACTGGGCACAGGACAGCGGTACACACGGACACACAACACTGCAAAAGTCCAGTCAAGATACTTGAAAATCCTCTGTGCGgtGCTTCTTCTTGGCTTGCTGGCTTTAATACTCACAATCATATTTTTACTGAAACTCCGCTGCAGTGATAAAGTCATTGACAGCTGTAAAAATAGATGCATATCCAAAAGTCATGATGGTAATGCAGGGTGTCGCTGCGATGCTGCTTGCGTAAATGAAGGCACCTGCTGTCTGGACTATGAGGAAGTGTGTTTGCAACCAACTCAGCTCTGGACGTGCTCGAAATTCCGCTGCGGTGAGGACCGTTTGCCCAGCAGCCTCTGCTCCTGCTCTGCAGACTGTGTGAAAGTGGGAGACTGCTGTGCAAACTATAAGAGGACATGTGAAGGTGAAAAGAGTTGGCTTCAAGAGGACTGTGAGGACATCAGGACTCCTCAGTGTCCCGCTGGGTTTTCTAAATCGCCGCTGCTGTTGGTATCTCTGGATGGATTCAGGGCAGGATACATGAATGCATACAGCGCTCTGCTTCCAGCCATCAGGAAACTCAGAGAATGTGGTACCTCCACCCCATATATGCGACCTGCTTATCCCACTAAGACCTTCCCGAATCATTACACCATAGTGACAggTCTCTATCCAGAAACACATGGAATTGTGGACAATAAGATGTATGATGTCAATCGCAATGCTTCATTCAGTTTAAAGGTTGATGAGAAATTCAATCCTTTGTGGTACCAAGGTGAACCAGTTTGGATCACAGCCATGAAAAACCATCTTAAAACAGCTACTTTCTTCTGGCCAGGATCCGATGTTAAAGTGCATGGACGATACCCAGATTACTGGATAAAGTATAACAGGAACATTCTTTTCGAAAAGAGGATAGCACAGATCTTTCAATGGTTGCATTTGCCTGAAGGAGAaagGCCAGACTTTTACACCTTGTACTTCGAAGAGCCAGATGCATCAGGACACAAATATGGACCAATGAGTACCCAGGTTATTGAGGCATTAATTAATGTTGACAGGCTGATTGGGATGTTGATGGATGGTCTGAAGGAAAGAAATCTGCACAAATGTGTCAACGTGGTTCTTGTATCAGACCACGGAATGGAAGAAGCGTCATGTAAGAAAGCTGCTTACGTCTCCAACTATCTGGACAACATCAATGACATCACTGTGATCCAGGGTCCTGCCGCGAGAGTCCGACCGCGACACGTGCCTGAGGAGTTCTTCTCCTTTGATTATGAAGGCCTGGTGAAGAATCTTTCGTGCAGAGAACCGAATCAGCCGATGAAACCGTATCTGAAGGAGCATCTGCCCAAACGGCTTCATTTTGCGAAGAACATCCGCATTGAGAGAGCACATCTGTACATGCAGCCGCAGTGGCAAGCAGCACTCAAACCAAGTGAAATTAAATACTGCCGCGGGGGCTTCCATGGTTCAGATAATGTTTTCAAGAACATGCAGGCCATTTTCATTGGATATGGACCAGGAATCCATTATAATACAACTGTGCCTCCTTTCGAGAACATTGAAGTCTACAATCTCTTATGTGATTTGCTGGGGATTTCTCCTGCTGCCAATAATGGCACCCATGGCAGTTTGAACCACATACTGAAAAAGCCGCGATATCAGCCGGTGTTTCCAGCAGAGCGTTCGGCTCCATCTACATGCAGTGCTGTCAGCAGCAGCTTGAGAGACCCTCGTGGGTGCACCTGTGACTCCCTCACCGAGGCCGAGGTGAACCGTCTGAACCAGCGTCTCATCAACTCAAATTCAGACTCTAATGTGAAGCCTGTTCATCTGCCGTTTGGGATCCCGCGGGTTCTCCAGGATCAGTCTGATTACTGTATTCTCCACCACAGCTCCTACATCAGCGGATACAGCCGAGACATCCTGATGCCCCTGTGGGTTTCTTACTCACTGAACACAACGGTTGTGCTGCATCCTTCTGCAGAATGGTGTGTGCGTGCAGATGTGCGAGTTCAAGCCAGTGACAGACAGTCTTGCTCCATCTATAAGAACAATTCCTCTATGAGCTTCGGCCTCCTGCATCCGCCCAacttCAGCCCTGCAGGAACTGAGCCAGACTCTTTAATTACAAGCAACATGGTGCCCATGTATCCTGGTTTCAAAGataTTTGGACTCACTTTCACAATTTTCTGCTGATAAAGTTTTCTGAGGAAATGAATGGCATCAATGTTGTGAGCGGACCGATATTTGATAATGATTTCGATGGAAACTACGACTTCATGAACAAGGGAGTCCTGAATGGAGCACCGATTCCTACACATTTCTTTATTATTCTTACAAGCTGTAAGAACTCATCTCTATCAGTGCGCCAGTGTGAAGGTCCTTTAGACGCCGTGAGCTTCATTCTGCCTCATCGTCCTGATCATCTGGAAACATGTCATAATGGCACCGACTACTCATGGTTTCAGGACTGGGTTCAGCTTCACGTGGCGCGAATCAGAGACATTGAACTTTTGACAGGCTTGAGTTTTTACCATGACCGGATATCTGTAGCAGAAACGCTACAACTCAAGACCAGACTCAAAACCTTCTAGAAAGATTAGTGAACTCAGACCTCATTTCACTGCAGACCCATTCAGAAAAGCATCTTTCAACATCAGAAAGAAGCGGCACTTTTAGCATACTCTAAAACAAAGACACAAGTTCATTCAGAGACTCTTTGATCTGGGAGTATAAAAAATGGGAGTATAAAACTTCTCTTTAATAAAATCTTTATTCTCagagtgaatttatttattacttgGGAAGTACCGACTGGCACTGTGAGTCCCTAAAATTCTGTTTTTCAAAGAAAACTGTTTTCCAGCACACATATGTTAGCGATTTAACTGTGGTTGCATGTAATCCTTCATTGAGCATGTTCAAAAAAGAAAGTTTTAAGAGTTTTGTGCCACTTTTGCCACAGGAATCACTCTACATTTCAACAtttagtgtgtgtctgtgtgttctgttctatttaaaattaaatttattccCTTCCTAGTAGTTTTAATGACGTATGTACAGCAGTGTTATCATGAAGTTTTTCTGCCCCTTCTGGTCAGATTGCAGAATTACATCAGATGAGAAAAAGctacatttatatatttgtttcatatttttttttttactctctcaGGTCAGTTTTGATAGACATTTGCATCcccattgtttatttcatttgtatgttACAGTTGTTATTCAAAATTTTTAGAGATAAAATAGGACATATAATGATTAAATGTTTCATATTTGTGATA
>TCONS_00034244
GAATCGCTTGTTCAAAATTTACATCATGAGCACTTTCTCATTGAGAGCTTTAGCTTTACTTCATATCTTTAAAATAGTGAAGCATTTGTGTCTGGTTGTTGGATTTGTTGTTTTGGCTGTGACGTTTTTGCCTGTAAACATAAAGAGTACCAACATCTGCTGTTCGAGGGTCATACAGTGCTCATGTTTCCTCTCGCTAATTTTACTCACTTCAACTGAAAGAGGAAGCTACTATTTTCAAGCATgacaagcatttaaaaaaaatgtttggtctTGTGTTTTAGGTTTTCTAAATCGCCGCTGCTGTTGGTATCTCTGGATGGATTCAGGGCAGGATACATGAATGCATACAGCGCTCTGCTTCCAGCCATCAGGAAACTCAGAGAATGTGGTACCTCCACCCCATATATGCGACCTGCTTATCCCACTAAGACCTTCCCGAATCATTACACCATAGTGACAggTCTCTATCCAGAAACACATGGAATTGTGGACAATAAGATGTATGATGTCAATCGCAATGCTTCATTCAGTTTAAAGGTTGATGAGAAATTCAATCCTTTGTGGTACCAAGGTGAACCAGTAagtaaatc
>TCONS_00034245
AAGTCGAACTCTGGTCTACTCTGTGTCTGTGAAACATTCAGGAATGGAAGAAGCGTCATGTAAGAAAGCTGCTTACGTCTCCAACTATCTGGACAACATCAATGACATCACTGTGATCCAGGGTCCTGCCGCGAGAGTCCGACCGCGACACGTGCCTGAGGAGTTCTTCTCCTTTGATTATGAAGGCCTGGTGAAGAATCTTTCGTGCAGAGAACCGAATCAGCCGATGAAACCGTATCTGAAGGAGCATCTGCCCAAACGGCTTCATTTTGCGAAGAACATCCGCATTGAGAGAGCACATCTGTACATGCAGCCGCAGTGGCAAGCAGCACTCAAACCAAGTGAAATTAAATACTGCCGCGGGGGCTTCCATGGTTCAGATAATGTTTTCAAGAACATGCAGGCCATTTTCATTGGATATGGACCAGGAATCCATTATAATACAACTGTGCCTCCTTTCGAGAACATTGAAGTCTACAATCTCTTATGTGATTTGCTGGGGATTTCTCCTGCTGCCAATAATGGCACCCATGGCAGTTTGAACCACATACTGAAAAAGCCGCGATATCAGCCGGTGTTTCCAGCAGAGCGTTCGGCTCCATCTACATGCAGTGCTGTCAGCAGCAGCTTGAGAGACCCTCGTGGGTGCACCTGTGACTCCCTCACCGAGGCCGAGGTGAACCGTCTGAACCAGCGTCTCATCAACTCAAATTCAG
>TCONS_00036555
AAGTCGAACTCTGGTCTACTCTGTGTCTGTGAAACATTCAGGAATGGAAGAAGCGTCATGTAAGAAAGCTGCTTACGTCTCCAACTATCTGGACAACATCAATGACATCACTGTGATCCAGGGTCCTGCCGCGAGAGTCCGACCGCGACACGTGCCTGAGGAGTTCTTCTCCTTTGATTATGAAGGCCTGGTGAAGAATCTTTCGTGCAGAGAACCGAATCAGCCGATGAAACCGTATCTGAAGGAGCATCTGCCCAAACGGCTTCATTTTGCGAAGAACATCCGCATTGAGAGAGCACATCTGTACATGCAGCCGCAGTGGCAAGCAGCACTCAAACCAAGTGAAATTAAATACTGCCGCGGGGGCTTCCATGGTTCAGATAATGTTTTCAAGAACATGCAGGCCATTTTCATTGGATATGGACCAGGAATCCATTATAATACAACTGTGCCTCCTTTCGAGAACATTGAAGTCTACAATCTCTTATGTGATTTGCTGGGGATTTCTCCTGCTGCCAATAATGGCACCCATGGCAGTTTGAACCACATACTGAAAAAGCCGCGATATCAGCCGGTGTTTCCAGCAGAGCGTTCGGCTCCATCTACATGCAGTGCTGTCAGCAGCAGCTTGAGAGACCCTCGTGGGTGCACCTGTGACTCCCTCACCGAGGCCGAGGTGAACCGTCTGAACCAGCGTCTCATCAACTCAAATTCAGACTCTAATGTGAAGCCTGTTCATCTGCCGTTTGGGATCCCGCGGGTTCTCCAGGATCAGTCTGATTACTGTATTCTCCACCACAGCTCCTACATCAGCGGATACAGCCGAGACATCCTGATGCCCCTGTGGGTTTCTTACTCACTGAACACAACGGTTGTGCTGCATCCTTCTGCAGAATGGTGTGTGCGTGCAGATGTGCGAGTTCAAGCCAGTGACAGACAGTCTTGCTCCATCTATAAGAACAATTCCTCTATGAGCTTCGGCCTCCTGCATCCGCCCAacttCAGCCCTGCAGGAACTGAGCCAGACTCTTTAATTACAAGCAACATGGTGCCCATGTATCCTGGTTTCAAAGataTTTGGACTCACTTTCACAATTTTCTGCTGATAAAGTTTTCTGAGGAAATGAATGGCATCAATGTTGTGAGCGGACCGATATTTGATAATGATTTCGATGGAAACTACGACTTCATGAACAAGGGAGTCCTGAATGGAGCACCGATTCCTACACATTTCTTTATTATTCTTACAAGCTGTAAGAACTCATCTCTATCAGTGCGCCAGTGTGAAGGTCCTTTAGACGCCGTGAGCTTCATTCTGCCTCATCGTCCTGATCATCTGGAAACATGTCATGT
>TCONS_00034246
GAGTCCGACCGCGACACGTGCCTGAGGAGTTCTTCTCCTTTGATTATGAAGGCCTGGTGAAGAATCTTTCGTGCAGAGAACCGAATCAGCCGATGAAACCGTATCTGAAGGAGCATCTGCCCAAACGGCTTCATTTTGCGAAGAACATCCGCATTGAGAGAGCACATCTGTACATGCAGCCGCAGTGGCAAGCAGCACTCAAACCAAGTGAAATTAAATACTGCCGCGGGGGCTTCCATGGTTCAGATAATGTTTTCAAGAACATGCAGGCCATTTTCATTGGATATGGACCAGGAATCCATTATAATACAACTGTGCCTCCTTTCGAGAACATTGAAGTCTACAATCTCTTATGTGGTAAACTCTTTTTTTTACTCGAATCATAAACATTTGAATGACATTCATATCATCATTTACATCAAATATTCCAGTAAAATTCATAGGTTGCTGAAAAAGGTTTTCCACATTCTTATGTACTTCCACATTCGTATGTATTATGTCTTTGTGAAAAAGTAAacatcaaatgtatatttaaattattaa
>TCONS_00034247
GAATCTTTGAGGGCCAAAACTCTGctaaatgaaatcaaagtaattgTGTTTATCTCTCTTTAGATTTGCTGGGGATTTCTCCTGCTGCCAATAATGGCACCCATGGCAGTTTGAACCACATACTGAAAAAGCCGCGATATCAGCCGGTGTTTCCAGCAGAGCGTTCGGCTCCATCTACATGCAGTGCTGTCAGCAGCAGCTTGAGAGACCCTCGTGGGTGCACCTGTGACTCCCTCACCGAGGCCGAGGTGAACCGTCTGAACCAGCGTCTCATCAACTCAAATTCAGACTCTAATGTGAAGCCTGTTCATCTGCCGTTTGGGATCCCGCGGGTTCTCCAGGATCAGTCTGATTACTGTATTCTCCACCACAGCTCCTACATCAGCGGATACAGCCGAGACATCCTGATGCCCCTGTGGGTTTCTTACTCACTGAACACAACGGTTGTGCTGCATCCTTCTGCAGAATGGTGTGTGCGTGCAGATGTGCGAGTTCAAGCCAGTGACAGACAGTCTTGCTCCATCTATAAGAACAATTCCTCTATGAGCTTCGGCCTCCTGCATCCGCCCAacttCAGCCCTGCAGGAACTGAGCCAGACTCTTTAATTACAAGCAACATGGTGCCCATGTATCCTGGTTTCAAAGataTTTGGACTCACTTTCACAATTTTCTGCTGATAAAGTTTTCTGAGGAAATGAATGGCATCAATGTTGTGAGCGGACCGATATTTGATAATGATTTCGATGGAAACTACGACTTCATGAACAAGGGAGTCCTGAATGGAGCACCGATTCCTACACATTTCTTTATTATTCTTACAAGCTGTAAGAACTCATCTCTATCAGTGCGCCAGTGTGAAGGTCCTTTAGACGCCGTGAGCTTCATTCTGCCTCATCGTCCTGATCATCTGGAAACATGTCATGT

Function

symbol description
enpp1 Predicted to enable nucleotide diphosphatase activity and phosphodiesterase I activity. Acts upstream of or within phosphate ion homeostasis and regulation of bone mineralization. Predicted to be located in extracellular region and membrane. Predicted to be integral component of membrane. Predicted to be active in cell surface. Is expressed in cleithrum and opercle. Human ortholog(s) of this gene implicated in several diseases, including arterial calcification of infancy; end stage renal disease; obesity; ossification of the posterior longitudinal ligament of spine; and type 2 diabetes mellitus. Orthologous to several human genes including ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1).

GO:

id name namespace
GO:0046034 ATP metabolic process biological_process
GO:0030500 regulation of bone mineralization biological_process
GO:0030505 inorganic diphosphate transport biological_process
GO:0055062 phosphate ion homeostasis biological_process
GO:0045599 negative regulation of fat cell differentiation biological_process
GO:0009143 nucleoside triphosphate catabolic process biological_process
GO:0009986 cell surface cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0046872 metal ion binding molecular_function
GO:0004528 phosphodiesterase I activity molecular_function
GO:0004551 nucleotide diphosphatase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0003824 catalytic activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040724-172 Predicted to enable nucleotide diphosphatase activity and phosphodiesterase I activity. Acts upstream of or within phosphate ion homeostasis and regulation of bone mineralization. Predicted to be located in extracellular region and membrane. Predicted to be integral component of membrane. Predicted to be active in cell surface. Is expressed in cleithrum and opercle. Human ortholog(s) of this gene implicated in several diseases, including arterial calcification of infancy; end stage renal disease; obesity; ossification of the posterior longitudinal ligament of spine; and type 2 diabetes mellitus. Orthologous to several human genes including ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1).

Ensembl:

ensembl_id ENSDARG00000005789

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00034242 False 1406 mRNA 0.40 8 13403281 13441967
TCONS_00034243 False 3389 mRNA 0.44 25 13403285 13521010
TCONS_00034244 False 593 lncRNA 0.40 3 13437298 13441439
TCONS_00034245 False 716 lncRNA 0.49 7 13462713 13491344
TCONS_00036555 False 1353 lncRNA 0.48 12 13462713 13517987
TCONS_00034246 False 543 lncRNA 0.39 5 13462847 13473656
TCONS_00034247 True 925 lncRNA 0.47 7 13485785 13517987

Neighbor

gene id symbol gene type direction distance location
XLOC_017186 ppp2r5a coding upstream 91363 13175379 ~ 13311918 (+)
XLOC_017185 dtl coding upstream 229116 13141408 ~ 13174165 (+)
XLOC_017184 BX547930.2 coding upstream 400098 13001068 ~ 13003183 (+)
XLOC_017183 BX547930.3 coding upstream 428560 12968914 ~ 12974721 (+)
XLOC_017182 BX547930.1 coding upstream 494156 12907233 ~ 12909125 (+)
XLOC_017188 sytl3 coding downstream 12534 13533544 ~ 13565720 (+)
XLOC_017189 NA coding downstream 119935 13640945 ~ 13665051 (+)
XLOC_017190 lpgat1 coding downstream 260769 13781779 ~ 13874340 (+)
XLOC_017191 nek2 coding downstream 362121 13883131 ~ 13913790 (+)
XLOC_017192 si:dkey-249p7.4 coding downstream 435096 13956106 ~ 13959214 (+)
XLOC_017179 NA non-coding upstream 721141 12642740 ~ 12682140 (+)
XLOC_017178 NA non-coding upstream 797448 12597008 ~ 12605833 (+)
XLOC_017194 NA non-coding downstream 493802 14014812 ~ 14041218 (+)
XLOC_017196 NA non-coding downstream 623066 14144076 ~ 14147484 (+)
XLOC_017198 NA non-coding downstream 966747 14487757 ~ 14623918 (+)
XLOC_017199 BX901920.1 non-coding downstream 1136131 14657141 ~ 14661432 (+)

Expression


Co-expression Network