XLOC_021255 (adra2a)


Basic Information

Item Value
gene id XLOC_021255
gene name adra2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007133.7
NCBI id CM002906.2
chromosome length 39133080
location 29584800 ~ 29586608 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00041687
gcGGTCTTCACACGCTCCATCGACGAGATGCGAGAGATTAACCATGCAGTTTTTCTCATGCTGAGCGACTTTAAACAGAGAAGTTGCACTCCGAGGGACGTTTCTTAGATGCCTTAATAAGTTTGTGGAAAGCTTCAGGCTTATTTCATTAAGATGTCAGAATGATTAGAATCGTCTCTGTTTGTCAGtaatatggaaaaagtgaagtgtcaTCAACCAAAAACATAATTTCACTCGTGTGGAGAAGAGACTGTAACTGTCAGCTATGATTTGTGGGGCCAATGCAACCAATGGGACCAATGCAACAAAGGAGTACACCCTGCTGGTGGCCCTACCACTGAGCGTTGCAGTGGGGctcctcatcctcctcatcaTCTTCGGCAATGTCCTGGTGATCATCGCCGTGTTCACGAGCCGAGCACTCCGGGCTCCCCAGAACCTCTTTCTGGTCTCGCTGGCCTCAGCTGACATACTGGTGGCCACTCTGGTGATGCCGTTCTCATTGGCGAATGAGCTGATGGGTATGTGGACGTTTGGGGGAGTTTGGTGTGAAATCTACCTGGCCTTGGACGTTCTTTTCTGCACAGCTTCAATTACTCACCTGTGCGCCATCAGTCTGGACAGGTACTGGTCAATTACGCAAGCCATCGAGTACAACCTGAAGCGAACACCGCAACGTATTAAGCGTATCATTTTTATCGTTTGGATCATCGCCGCCGTGATCTCCTGCCCCCCTCTTATAACAATGAAGAAATCTGAGGGGGATATCTGTGACATCAATAAGGAAAAATGGTACATAGTCTCATCTTGCATTGGCTCGTTTTTCCTGCCTTGCATCATCATGGTCCTCGTCTACATCCGGATCTATCAAATTGCCAAGAAGAGAACTAGAGCACCTCCTGGGGACCACAGGAAAAACGAAGTGGGAAAGAAGGAAAACGACCCGCATGAGAAGCTCAATGGAATTCAGAATGCAGAACCGGACGACAAGGATGAAATAAATGGTGTGGACATGGAGGAATCCTCCTCCTCAGACCACAAGGTCTCCAATCCTTGCTCCCTCAAGAAGAAAAGCTCAAAAGGAAAGACCAAGTTGAGCCAAATCAAACCAGGCGATGGAGACAAAACCGAGGCCTGCCAGACTACCAAAGCAAGCAGATGGAAGGGCCGTCAAAACCGAGAGAAGCGGTTCACATTTGTTCTGGCGGTGGTCATAGGCGTGTTCGTCATTTGTTGGTTCCCGTTCTTCTTCACCTACACATTCACAGCGTTTTGTGACTGCTGTGTGCCTGAAACACTTTTTAAGTTCTTCTTCTGGTTCGGCTACTGCAACAGCTCCCTCAATCCCATTATATACACTATCTTCAATAACGACTTCCGAAGATCCTTTAAAAAGATCCTCTGCCGGAGAGATAAGAGGAGAGTGGTGTGA

Function

symbol description
adra2a Enables alpha2-adrenergic receptor activity. Involved in adenylate cyclase-inhibiting adrenergic receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including gut; heart; integument; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and type 2 diabetes mellitus. Orthologous to human ADRA2A (adrenoceptor alpha 2A).

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway biological_process
GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway biological_process
GO:0007165 signal transduction biological_process
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004930 G protein-coupled receptor activity molecular_function
GO:0004935 adrenergic receptor activity molecular_function
GO:0004938 alpha2-adrenergic receptor activity molecular_function
GO:0051379 epinephrine binding molecular_function

KEGG:

id description
ko04022 cGMP-PKG signaling pathway
ko04080 Neuroactive ligand-receptor interaction
ko04030 G protein-coupled receptors

ZFIN:

id description
ZDB-GENE-021010-1 Enables alpha2-adrenergic receptor activity. Involved in adenylate cyclase-inhibiting adrenergic receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including gut; heart; integument; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and type 2 diabetes mellitus. Orthologous to human ADRA2A (adrenoceptor alpha 2A).

Ensembl:

ensembl_id ENSDARG00000040841

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00041687 True 1432 mRNA 0.48 2 29584800 29586608

Neighbor

gene id symbol gene type direction distance location
XLOC_021254 pdgfba coding downstream 248491 29312228 ~ 29336309 (-)
XLOC_021253 pvalb7 coding downstream 342453 29165330 ~ 29242347 (-)
XLOC_021252 cbx6a coding downstream 501686 29075042 ~ 29083114 (-)
XLOC_021251 NA coding downstream 660530 28911878 ~ 28924270 (-)
XLOC_021250 gtpbp2b coding downstream 713013 28858225 ~ 28871787 (-)
XLOC_021256 shoc2 coding upstream 10038 29596646 ~ 29640181 (-)
XLOC_021257 pdcd4b coding upstream 69373 29655981 ~ 29689981 (-)
XLOC_021258 NA coding upstream 105292 29691900 ~ 29836026 (-)
XLOC_021259 smc3 coding upstream 271927 29858535 ~ 29906764 (-)
XLOC_021260 dusp5 coding upstream 324718 29911326 ~ 29922872 (-)
XLOC_021249 NA non-coding downstream 795201 28787312 ~ 28789599 (-)
XLOC_021248 dre-mir-216b non-coding downstream 804467 28780257 ~ 28780333 (-)
XLOC_021247 dre-mir-216a non-coding downstream 804763 28779949 ~ 28780037 (-)
XLOC_021246 dre-mir-217 non-coding downstream 804988 28779715 ~ 28779812 (-)
XLOC_021261 NA non-coding upstream 665729 30252337 ~ 30272700 (-)
XLOC_021262 NA non-coding upstream 795691 30382299 ~ 30383228 (-)
XLOC_021263 BX649448.2 non-coding upstream 797391 30383999 ~ 30384127 (-)
XLOC_021265 NA non-coding upstream 885612 30472220 ~ 30557523 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000015_06473902_06477166 ADRA2A coding CI01000015 null 6472932 ~ 6477232 (+)