XLOC_022131 (mipb)


Basic Information

Item Value
gene id XLOC_022131
gene name mipb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 6637611 ~ 6641223 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00043725
TGTCAGACCAGCTCTACTTGGTGTGGGCAGGATATGCTCTGTAACCTCTTCTGTGTCGCTCAACTAGAATTAGCCCTATAGATTTAGCTTGTAGCATCGATGTTCAGGCCTCTCTGACAAAACCCTCCAGATTTTctacgcgtgcacacacacacacaaccacacacacctCATGTTTCTTTAGCAGTCCGGGTGTTGTGCAGGCGAAGAGAAACAGCGCTGGCAGAGAAGACCCGTGTGCGGCTACATGTGTGACCATTTACTCACGGCTTCCCACACAGCCTTAGCTAACGGCTAGATCTATTAGGCCTAATTATTGATCTGTTTTTGAGGAACTTTTAGTGTACTTGGcaaaaaaaaaggacattttattttttttaaagacatttttcttGCCAActcgaaaaaacaaacaaaaaagtttcgGTTTTGAATTTAGTTGGGACTCATAAATCATAATGTGGGAGTTTCGCTCTATGATGTTTTGGAGGGCGGTGTTTGCCGAGTTTTTCGGCACCATGTTCTTCGTGTTCTTCGGGATGGGTGCCGCTCTACGCTGGACCACCGGGCCGTACCATGTCTTCCACACTGCTCTCTGCTTTGGTTTTGCTGCTGCCACACTCATTCAATCCATCGGCCACATCAGCGGAGGACACATTAATCCGGCTGTCACCTTTGCATACTTAGTCGGCTCTCAGATGTCTGTGTTCAGAGCTTTCTTCTACATTTGTGCTCAGTGTCTGGGGGCCATGGCAGGAGCCGCGGCGCTCTACGGAGTTACACCCAACAACATGAGGGGCACGATGGCACTTAACACGCTTCAGCCTGGCATGAGTCTGGGAATGGCCACCACAGTGGAGGTGTTCCTCACTATGCAGTTGGTGGTCTGCGTTTTCGCTGTCACTGATGAAAGAAGAAATGGACGTCTGGGTTCTGCTGCTCTGTCCATTGGATTCTCTGTTACTATGGGCCACCTGATGGGGATGTACTACACTGGAGCTGGAATGAACCCAGCCAGGTCTTTCGCCCCTGCTGTAATCACCAGGAATTTCATCAACCACTGGGTGTACTGGGTGGGTCCGATGATTGGTGCTGCTATGGGTGCCATCTTCTATGACTTCTTCCTGTTCCCCCGTATGCGGGGCTTCTCTGAGCGGCTAGCCACGCTGAAGGGCAGTCGACCCCCAGAGGCCGAGAACCAGCAGGAGACCCGCGGGGAGCCCATCGAGCTCAAGACTCAAACCCTATAAACCTGCAGAGAAGTTGTGGACCGAATCTGGCTCTACCTCACTGGACCATCTCACTGCCCTGAGCAGCCAATAAAACTCCTGCGACGCAACACCAGAGACCCGCAGAGGGTCGCATTTACACGGCAAGATCAGTAAGGGAGCAGAAATGAGTACATTACTCCGGGTAGTATTCTAGGTTTGCTGCTAGTACCAGTGCAGGGTGGAGGGCGGTTCTGAGGTGGGGTTGTGGGCGGGGCTTATGTTGTGGGAGGGGCTGTAGCAATTTATTTAGGCATGCTTTTCACTTTTCATCTGACTTCATTTTCACAATTCATTTTCAATTTTTCGTTTTCTACAAACAACAAGATGTGGATGTACGCAACTTAACCAGGGTTTCAcactttttattttctgtgaGAGTTCAAGTGAGTGCAGCTTTGTgggtctttctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgagggagagcGTGCCaaggtatgtttgtgtgtttcgCTTGTGCACGACcaagtgtactgtatgtgtgtgtgtgtgagtgagtgagtgtgtctgTCATCTGAGCATTTCTTTTGGGTTTTTATCATTACAGCTCGCTCGTGTTTGTaccatgcttgtttttttttccctttcttatTTTTACGGGACTCTAAAACACCCCAAACTGTATTGTTTGCTATGATCTTCCATTCACTTTTTATTCACACAAACCACCCATGGACTGAGCTGTTTTAAACACAGCCAGTCCTTGCCACCAGTCTTTACAATTACTTCGAGTTTACAGTGTCTGTGTTGCCTTTCATAAAATCTTGTTTGAGGATAACATCCATGACTGGGCAAGTaaagcaatatgaatcatatctgaatgcaaataaatacatgaaaagaAA

Function

symbol description
mipb Enables water transmembrane transporter activity. Acts upstream of or within lens fiber cell morphogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Is expressed in eye; lens; lens fiber cell; and solid lens vesicle. Human ortholog(s) of this gene implicated in cataract and cataract 15 multiple types. Orthologous to human MIP (major intrinsic protein of lens fiber).

GO:

id name namespace
GO:0070309 lens fiber cell morphogenesis biological_process
GO:0002088 lens development in camera-type eye biological_process
GO:0055085 transmembrane transport biological_process
GO:0006833 water transport biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0015267 channel activity molecular_function
GO:0005372 water transmembrane transporter activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050706-86 Enables water transmembrane transporter activity. Acts upstream of or within lens fiber cell morphogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Is expressed in eye; lens; lens fiber cell; and solid lens vesicle. Human ortholog(s) of this gene implicated in cataract and cataract 15 multiple types. Orthologous to human MIP (major intrinsic protein of lens fiber).

Ensembl:

ensembl_id ENSDARG00000013963

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00043725 True 2138 mRNA 0.47 4 6637611 6641223

Neighbor

gene id symbol gene type direction distance location
XLOC_022130 bmp7b coding downstream 115512 6421414 ~ 6522099 (-)
XLOC_022129 BX323087.2 coding downstream 217761 6399839 ~ 6419850 (-)
XLOC_022128 NA coding downstream 283432 6328231 ~ 6354179 (-)
XLOC_022127 NA coding downstream 312697 6313582 ~ 6324914 (-)
XLOC_022126 csrp1a coding downstream 818619 5765514 ~ 5818992 (-)
XLOC_022132 CR450824.2 coding upstream 7848 6649071 ~ 6660985 (-)
XLOC_022133 baz2a coding upstream 32223 6673446 ~ 6722101 (-)
XLOC_022134 ptges3b coding upstream 94893 6736116 ~ 6749820 (-)
XLOC_022135 FP102169.1 coding upstream 113687 6754910 ~ 6765653 (-)
XLOC_022136 ftr59 coding upstream 204412 6845635 ~ 6852296 (-)
XLOC_022121 dre-let-7e non-coding downstream 1206094 5431418 ~ 5431517 (-)
XLOC_022120 dre-let-7a-5 non-coding downstream 1206292 5431196 ~ 5431319 (-)
XLOC_022141 NA non-coding upstream 343449 6984672 ~ 6997683 (-)
XLOC_022144 NA non-coding upstream 529643 7170866 ~ 7217574 (-)
XLOC_022145 NA non-coding upstream 559020 7200243 ~ 7202861 (-)
XLOC_022146 mir1-1 non-coding upstream 568934 7210157 ~ 7210262 (-)
XLOC_022147 NA non-coding upstream 668340 7309563 ~ 7323879 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000021_00748689_00750893 AQP6, MIPB, MIPA, MIP coding CI01000021 null 748141 ~ 751000 (+)