XLOC_025953 (bglap)


Basic Information

Item Value
gene id XLOC_025953
gene name bglap
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 1405504 ~ 1434135 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00050828
acacagatcagctGACACAGAAGCGAATATGAAGAGCCTGACAGTCCTGATCTTCTGCTGCCTGATGACTGTGTGTCTGAGCGCAGGTCTTCCTGACTCCTCAGATACTAAACTATTGAGTGCTGCAGAATCTCCTAATCATGAAGGTGTGTTTGTGAAGCGTGACGTGGCCTCTATCATCATGAGACAGAAGAGGGCTGGAACTGCACCTGGAGACCTGACTCCATTTCAGCTCgagagtctcAGAGAGGTGTGTGAGACAAATGTGGCCTGTGAGCACATGATGGACACGTCTGGAATCATCACCGCCTATAAAACCTACTATGGGCCCATTCCCTtctagaaccacacacacacacacacacacacaca
>TCONS_00050829
ctctgcaGACTCTCAGGAGAGCCGCGAGTCATTGGAGGGTCTTCCTGACTCCTCAGATACTAAACTATTGAGTGCTGCAGAATCTCCTAATCATGAAGGTGTGTTTGTGAAGCGTGACGTGGCCTCTATCATCATGAGACAGAAGAGGGCTGGAACTGCACCTGGAGACCTGACTCCATTTCAGCTCgagagtctcAGAGAGGTGTGTGAGACAAATGTGGCCTGTGAGCACATGATGGACACGTCTGGAATCATCACCGCCTATAAAACCTACTATGGGCCCATTCCCTtctagaaccacacacacacacacacacacacaca
>TCONS_00050830
cagacagTGCTCCTGCAGTCATGTGTGTGTCTcctcagtgtgtgtttctgtgtgttgttCTGGCTCTTGGTGCTGCTGCAGCTTATGACTCTCAGGAGAGCCGCGAGTCATTGGAGGtgtTTGTGAACCCATATCAGGCCAACGCCTTCATGAGGAACACACAACACAACCCCTACATCTACCGAAGgATGAAGTCTCCAGCTGAGCGGCGTGCGGAGGTGTGTGAGGACTTCTCTCCGTGTCGTGTGTTTGCGCTGCGCTACGGTTCTCAGGTGGCCTATCAGACCTTCTTCAGCCCGCAGCAGCTCAGGGCCAATCAGCAGCTGCGCAGATACTGAGCCCCGCCTCCTCATTTACATACCAGCAGCCAGCTCTCCTcatatattagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgaatgacactgatcCTGCATCTGCTCTCTGAACACCAGCAGCTCTCATAGACACCTGTACATCATCATCAGTTCTGCTCACAGCTCTTCTGCTTGTAGAGGATTTGCTGAACATGAGGAGCTCTCAATAAACCCTGGACACGCTTCATGATGGAGACGTGTGCTGCACAGCATTTATTCA

Function

symbol description
bglap Predicted to enable calcium ion binding activity and hydroxyapatite binding activity. Predicted to be a structural constituent of bone. Acts upstream of or within response to mechanical stimulus. Predicted to be active in extracellular region. Is expressed in several structures, including osteoblast; renal tubule; scale; skeletal system; and trabecular layer. Human ortholog(s) of this gene implicated in osteoarthritis; osteoporosis; prostate cancer; rheumatoid arthritis; and vitamin K deficiency bleeding. Orthologous to human BGLAP (bone gamma-carboxyglutamate protein).

GO:

id name namespace
GO:0032571 response to vitamin K biological_process
GO:0060348 bone development biological_process
GO:0009612 response to mechanical stimulus biological_process
GO:0001503 ossification biological_process
GO:1900076 regulation of cellular response to insulin stimulus biological_process
GO:0001649 osteoblast differentiation biological_process
GO:0005576 extracellular region cellular_component
GO:0008147 structural constituent of bone molecular_function
GO:0046848 hydroxyapatite binding molecular_function
GO:0005509 calcium ion binding molecular_function

KEGG:

id description
ko04928 Parathyroid hormone synthesis, secretion and action

ZFIN:

id description
ZDB-GENE-050113-4 Predicted to enable calcium ion binding activity and hydroxyapatite binding activity. Predicted to be a structural constituent of bone. Acts upstream of or within response to mechanical stimulus. Predicted to be active in extracellular region. Is expressed in several structures, including osteoblast; renal tubule; scale; skeletal system; and trabecular layer. Human ortholog(s) of this gene implicated in osteoarthritis; osteoporosis; prostate cancer; rheumatoid arthritis; and vitamin K deficiency bleeding. Orthologous to human BGLAP (bone gamma-carboxyglutamate protein).
ZDB-GENE-060928-1 Predicted to enable calcium ion binding activity. Predicted to act upstream of or within cartilage development; cell differentiation; and ossification. Predicted to be located in collagen-containing extracellular matrix and extracellular region. Predicted to be active in extracellular matrix. Is expressed in caudal fin; gill filament; sensory system; skeletal system; and trabecular layer. Human ortholog(s) of this gene implicated in arteriosclerosis; calcinosis; and myocardial infarction. Orthologous to human MGP (matrix Gla protein).

Ensembl:

ensembl_id ENSDARG00000058414 ENSDARG00000086189 ENSDARG00000095818

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00050828 False 372 mRNA 0.49 4 1405504 1408487
TCONS_00050829 False 324 processed_transcript 0.50 4 1405504 1433905
TCONS_00050830 True 637 mRNA 0.52 4 1414870 1434135

Neighbor

gene id symbol gene type direction distance location
XLOC_025952 wbp11 coding downstream 5195 1395079 ~ 1400309 (-)
XLOC_025951 ddx47 coding downstream 16568 1387435 ~ 1388936 (-)
XLOC_025950 ddx47 coding downstream 18212 1378098 ~ 1387292 (-)
XLOC_025949 FP236551.1 coding downstream 40558 1352555 ~ 1364946 (-)
XLOC_025948 tmem106c coding downstream 66284 1323732 ~ 1339220 (-)
XLOC_025954 NA coding upstream 22007 1456142 ~ 1490157 (-)
XLOC_025955 polr2f coding upstream 77064 1511199 ~ 1520657 (-)
XLOC_025956 NA coding upstream 152699 1586834 ~ 1685178 (-)
XLOC_025957 NA coding upstream 191222 1625357 ~ 1716973 (-)
XLOC_025958 micall1b.2 coding upstream 408481 1842616 ~ 1859198 (-)
XLOC_025944 NA non-coding downstream 198254 1207098 ~ 1207250 (-)
XLOC_025941 NA non-coding downstream 240574 1163765 ~ 1164930 (-)
XLOC_025940 NA non-coding downstream 258951 1132906 ~ 1146553 (-)
XLOC_025939 NA non-coding downstream 377091 1011480 ~ 1028413 (-)
XLOC_025938 NA non-coding downstream 432705 972541 ~ 972799 (-)
XLOC_025959 BX465228.2 non-coding upstream 428736 1862871 ~ 1875971 (-)
XLOC_025960 BX465228.1 non-coding upstream 446747 1880882 ~ 1888204 (-)

Expression


Co-expression Network