XLOC_030837 (fgf10b)


Basic Information

Item Value
gene id XLOC_030837
gene name fgf10b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 8769069 ~ 8817841 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00059983
CCCAGACAGGGCAGGGGGAATTGTGGGCGATGAGGAGGGGTGAGAGTCAAAGAACGGAGGAAGGGACTGAAAATGACAGACAGGAGTAAGGGAGTAAGGAGGAGGAGTAGACAGCAGCATTTCTGTGAAGCTCCTAAAGATCACACCAAGACACCCTTGATCCCACAAACTCATTCTGAGACTTGGAAAAGACACTAGCTTGCCTGGACACTTGCTTGCTTCCATGATAACCCTTCCTAGATGGGATTAATAAAGTACTCACCATCAGAAGACACTACTTAATTCCACAGCTTCATGGTTACTTCAGCACTTTTGTGTGGACTTCTGAGAAGCGAGAGGCTTCAGTGCACATTGGTTGAGCAGCATGTCCCATGAGGAGTACCATGAGGAGATGGACAGTGAGTAAGAGTGTGTCTGCGTGCTGGTCGGTGTGTGTCGTTTATTTTCTCGCGGTCTCCGTCACCTGCCGCGGCGCATGCCTCCGGGTCTCCAGCTCCGCATCCACCTCCACCTCCGGCCGGCATGCGCGCAGCTACGTGCACCTCCAGGGCGACGTGCGCCAGAGGAGACTCTTCTCCTTCCAGAAGTTCTTCCTTAGGATCGGGAAGGACGGGAAAGTGAACGGCACCAAGAGCGAAGACGACCCGTACAGTATATTGGAGATCACATCGGTGGATGTTGGGGTTGTTGCTATCAGAGGTCTTGGCAGTAATCTTTACCTGGCTATCAGTAAGAAAGGGGAGCTGTTTGGAGTGAGAAACTACGGCACGAATTGCCGCCTGAAGGAGCGCATCGAGGAGAACGGCTATAACACATATGCATCGGCCAAGTGGAAGAACAATAAGCGGCAGATATTTGTAAGTCTGAGCGCTCACGGACGGCCTCTACGTGGCAGGAAAAACCGCAGGAAGAACACGGCTACTCACTTTTTGCCCATGGTGGTGTGACGCAGACAACGATGGCGGATAAAGACTCTCTGTAGCAGCGTGTGGGACGGGTTCTGTCATTCCTTGATCCTCCATTGCTCCTTGCACTATGCACTATGCTCATTCCAGTTGATATTACGTGGTAAACAAACTCAAAAAAAGAGGAAAGTTCACCAATTGATTTGCTTTGGGCATCATTAATCTGCAGTTATGGATTATGTGTGCAAGAGTTTCCTTCAAGCTCTCTTTAATAGAATCATATTTCAGAAAATGTCGGCTTAGATTTAATTTTTAATGGACATGATGAACATAAAGCTGAACGAGAGAGACAGGAGAGAGAGGGATGTATATGGGAAAATTTGTATCTTTTAAGACTGTTTTGGACTGCTTTGagatgaataaattatttatttgtatcgtatttaaatgcaaaaatactctaaaaatgtattaaaaagcaTATAATATGGATAACTTCTAATTCCTGTGAAATAAAGTCTATTTTGTTATCCTCCTGTAGAGCAGCGTGTGCTGTGTTTcttattcatgtttgtttgtttatttattcttgaAGTTAATTTCATTATTAGTGGATTTTAGTTCAGTAAAGTAATTGAACTTaacattattcattccttcattcatttagtccctttatttatcaggggtcgccacagtgaaatgagccaccgactaatccagcatatgttttacacagcggatgcccttctagctgcaacccagcactgggaaattaaatagcattattattttataaatagttattattgttaaattaaaccacaattaaat

Function

symbol description
fgf10b Predicted to enable chemoattractant activity; growth factor activity; and type 2 fibroblast growth factor receptor binding activity. Acts upstream of or within animal organ development and ectodermal placode development. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in digestive system; lateral line system; mesoderm; pronephros; and tail bud. Human ortholog(s) of this gene implicated in LADD syndrome and aplasia of lacrimal and salivary glands. Orthologous to human FGF10 (fibroblast growth factor 10).

GO:

id name namespace
GO:0090263 positive regulation of canonical Wnt signaling pathway biological_process
GO:0010628 positive regulation of gene expression biological_process
GO:0010634 positive regulation of epithelial cell migration biological_process
GO:0030154 cell differentiation biological_process
GO:0050918 positive chemotaxis biological_process
GO:0071599 otic vesicle development biological_process
GO:0031016 pancreas development biological_process
GO:0009887 animal organ morphogenesis biological_process
GO:0060173 limb development biological_process
GO:0050679 positive regulation of epithelial cell proliferation biological_process
GO:0008543 fibroblast growth factor receptor signaling pathway biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:0008284 positive regulation of cell population proliferation biological_process
GO:0071696 ectodermal placode development biological_process
GO:0061033 secretion by lung epithelial cell involved in lung growth biological_process
GO:0001889 liver development biological_process
GO:0001934 positive regulation of protein phosphorylation biological_process
GO:0030334 regulation of cell migration biological_process
GO:0042060 wound healing biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005104 fibroblast growth factor receptor binding molecular_function
GO:0005111 type 2 fibroblast growth factor receptor binding molecular_function
GO:0008083 growth factor activity molecular_function
GO:0042056 chemoattractant activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-060828-1 Predicted to enable chemoattractant activity; growth factor activity; and type 2 fibroblast growth factor receptor binding activity. Acts upstream of or within animal organ development and ectodermal placode development. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in digestive system; lateral line system; mesoderm; pronephros; and tail bud. Human ortholog(s) of this gene implicated in LADD syndrome and aplasia of lacrimal and salivary glands. Orthologous to human FGF10 (fibroblast growth factor 10).

Ensembl:

ensembl_id ENSDARG00000100475

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00059983 True 1739 mRNA 0.44 3 8769069 8817841

Neighbor

gene id symbol gene type direction distance location
XLOC_030835 mybbp1a coding downstream 3641 8712798 ~ 8765428 (-)
XLOC_030836 BX897662.2 coding downstream 46026 8722928 ~ 8723043 (-)
XLOC_030834 paip1 coding downstream 57912 8684652 ~ 8711157 (-)
XLOC_030833 zgc:153352 coding downstream 86479 8661414 ~ 8682590 (-)
XLOC_030832 NA coding downstream 124886 8640678 ~ 8644183 (-)
XLOC_030838 adamts12 coding upstream 14458 8832299 ~ 8910703 (-)
XLOC_030839 AL928901.1 coding upstream 141887 8959728 ~ 8963775 (-)
XLOC_030840 NA coding upstream 212399 9030240 ~ 9031751 (-)
XLOC_030841 atp5meb coding upstream 252541 9070382 ~ 9073433 (-)
XLOC_030842 kcnv2b coding upstream 260357 9078198 ~ 9090178 (-)
XLOC_030831 BX897662.3 non-coding downstream 129069 8637804 ~ 8640000 (-)
XLOC_030830 BX897662.1 non-coding downstream 133677 8635268 ~ 8635392 (-)
XLOC_030826 NA non-coding downstream 352236 8409461 ~ 8416833 (-)
XLOC_030843 NA non-coding upstream 289244 9107085 ~ 9127559 (-)
XLOC_030844 NA non-coding upstream 326526 9144367 ~ 9146777 (-)
XLOC_030845 AL845369.1 non-coding upstream 348554 9166395 ~ 9170534 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000338_00162704_00178900 FGF10, FGF10A, FGF10B misc CI01000338 null 162165 ~ 179023 (-)