XLOC_003361 (gdf11)


Basic Information

Item Value
gene id XLOC_003361
gene name gdf11
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 15613218 ~ 15756385 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00006582
GGTACAGTTGAAAAAAGCTTAGTATCAGCTGGAGCAGATAGATTATAAAATGATattaaaacaaactgaaatgCATTAAGGAACGATATTTAAAAGAATTCGATAAAAGCCGtcgctttgtttttttttttatgaaataggCTACATCTTCTAGAACGTCTTTATtcgtatttatatatttaattcgtctttcaaacaaaaataaagacaataaCAACTGTAgcctatttttaaaaatcaagagaaaaccATTGTTTCCTGATATTTAACAACATGAAAAGGTATAACTTTTTACTGTGCTTAACGGTACTTATTTCTCTGGGACTGTCCGGAAGCGATGAGCCGAACCTCTTTCTAGCCCCACTGAGCGAGATGTCCTCTGATATTGGAGTTTCTCTCTTTGACGTGGATGATGTGGAGTCTTCTGAGTGTTCAGCGTGCGTGTGGAGAGAACAGAGTAAAGTCTTGCGACTGGAAACAATTAAATCACAAATACTTAGCAAACTGCGCTTAAAACAAGCACCCAACATCAGCAGAGAGGTGGTTAATCAGCTTCTTCCCAAAGCACCTCCGCTGCAGCAGCTGTTGGACCATCATGACTTCCAAGGGGACGCATCTTCCTTAGAGGATTTCATAGACGCCGATGAGTATCACGCCACCACCGAGTCCGTCATCACAATGGCTTCAGAGCCTGAACCTCTGGTGCAGGTGGATGGGAAACCGACCTGTTGTTTCTTCAAGTTTAGTCCAAAACTGATGTTTACCAAGGTCCTGAAGGCGCAGCTTTGGGTTTATCTGCAGCCACTAAAACAAACGTCCACTGTTTACCTGCAGATCCTGCGTCTTAAACCTATCACTGAGCAGGGAAGCCGACATATACGTATCCGATCACTCAAGATTGAGCTTGATTCTCAAGCAGGTCACTGGCAGAGCATTGACTTCAAACATGTGTTGCAGAACTGGTTCAAGCAGCCACATACAAACTGGGGTATTGATATAAATGCCTATGATGAAAGTGGCAATGACCTGGCTGTCACATCTTTGGGGCCTGGAGAGGAGGGACTGCAGCCGTTCCTGGAGGTCAAGATTCTTGAAACAACCAAGCGCTCACGGAGGAATCTGGGTCTTGACTGTGATGAGCACTCCACAGAATCTCGCTGTTGTCGCTATCCACTTACAGTGGACTTTGAAGCTTTTGGCTGGGACTGGATCATTGCACCTAAACGTTACAAGGCAAACTATTGCTCAGGGCAGTGTGAGTACATGTTTATGCAAAAGTACCCACATACCCATCTGGTGCAGCATGCAAATCCTAGAGGGTCTGCAGGGCCATGCTGCACCCCAACAAAGATGTCACCGATAAACATGCTTTACTTCAATGACAAACAGCAAATAATCCATGGCAAAATCCCAGGAATGGTGGTGGACCGTTGTGGCTGTTCATAGAGTTTTGCATTTTGGTAGAGATAAATAAGCTAAGTAATGGAGGGGGGAGAGTGTCAGGGCTTAATTCAAGAATGCAAGTCTCTACATTTTCCTTATATTGTTTCTTAAATTCCTTTGAATGAATTTGCtgtacagaaagaaaaaaaaatgtgtagctttttttaataatcacaGTAAAAAGTCTTTACATCAAAGACAAAAGCTAATTtctctttattatttaaatttatattatatctaccaacaatgttttttattgtgTTGGGTCACTCTCAAAAAAA

Function

symbol description
gdf11 Predicted to enable cytokine activity. Acts upstream of or within anterior/posterior pattern specification. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; gonad; head; intermediate cell mass of mesoderm; and tail bud. Orthologous to human GDF11 (growth differentiation factor 11).

GO:

id name namespace
GO:0060395 SMAD protein signal transduction biological_process
GO:0009952 anterior/posterior pattern specification biological_process
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005125 cytokine activity molecular_function
GO:0008083 growth factor activity molecular_function

KEGG:

id description
ko04060 Cytokine-cytokine receptor interaction
ko04052 Cytokines and growth factors

ZFIN:

id description
ZDB-GENE-040427-2 Predicted to enable cytokine activity. Acts upstream of or within anterior/posterior pattern specification. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; gonad; head; intermediate cell mass of mesoderm; and tail bud. Orthologous to human GDF11 (growth differentiation factor 11).

Ensembl:

ensembl_id ENSDARG00000044924

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00006582 True 1727 mRNA 0.41 3 15613218 15756385

Neighbor

gene id symbol gene type direction distance location
XLOC_003360 cdk5rap1 coding upstream 26084 15480695 ~ 15587134 (+)
XLOC_003359 NA coding upstream 271805 15339344 ~ 15341413 (+)
XLOC_003358 CR550302.2 coding upstream 594694 15017185 ~ 15018524 (+)
XLOC_003357 CR550302.3 coding upstream 642307 14937904 ~ 14970911 (+)
XLOC_003356 CU019562.2 coding upstream 708241 14902709 ~ 14904977 (+)
XLOC_003362 FP016142.6 coding downstream 19687 15776072 ~ 15779251 (+)
XLOC_003363 FP016142.2 coding downstream 42998 15799383 ~ 15801396 (+)
XLOC_003364 FP003590.2 coding downstream 65048 15821433 ~ 15868456 (+)
XLOC_003365 pank4 coding downstream 121958 15878343 ~ 15915788 (+)
XLOC_003366 draxin coding downstream 174803 15931188 ~ 16013114 (+)
XLOC_003318 CR450764.6 misc upstream 2901222 12711700 ~ 12711996 (+)
XLOC_003317 CR450764.16 misc upstream 2918955 12693967 ~ 12694263 (+)
XLOC_003316 CR450764.11 misc upstream 2927619 12685304 ~ 12685599 (+)
XLOC_003315 CR450764.18 misc upstream 2933190 12679732 ~ 12680028 (+)
XLOC_003314 CR450764.9 misc upstream 2989367 12623555 ~ 12623851 (+)
XLOC_003369 CR854846.2 misc downstream 366401 16122786 ~ 16123082 (+)
XLOC_003355 CU019562.3 non-coding upstream 749676 14862286 ~ 14863542 (+)
XLOC_003353 BX571942.1 non-coding upstream 972901 14431273 ~ 14640317 (+)
XLOC_003368 ctbs non-coding downstream 314053 16070438 ~ 16083608 (+)
XLOC_003374 NA non-coding downstream 1336693 17093078 ~ 17170177 (+)
XLOC_003375 CR769769.1 non-coding downstream 1381463 17137848 ~ 17141887 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000207_00392356_00468497 GDF11 coding CI01000207 null 392356 ~ 468497 (+)