XLOC_034635 (ndufs2)


Basic Information

Item Value
gene id XLOC_034635
gene name ndufs2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007118.7
NCBI id CM002891.2
chromosome length 74282399
location 19043750 ~ 19068539 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00067430
CGCCAGAGCCCCAGTGAAAGAGCGGCCGTGAAGCTCTCAGCACAGAAGCAGAGCGCTGACAGAAGGGAAGATGGCGGCTACAATGCTGAGGTCGCTCTCTAGACTCGGACGTCcttcagttttattaaacagtaatGTCAGCTCTCCAGCCTGTGCTCTGATTCAGACGAGGCAGAAGCAATGGCAGCCAGATGTGGAGTGGGTGGAGCAGTTCTCTGGAGTGGTGATGTATCCCTCTCCCTCCGTTGCCAAATGGACACCTCCACCTTGGAATGATAAGGATCCACCAGCACAGAAGGATTTGTCCAACCTCACCATCAACTTCGGGCCTCAGCACCCTGCAGCTCATGGAGTGCTGCGCTTGGTGATGGAGCTCAGCGGAGAGTCTGTGAAGAAATGCGACCCTCACATCGGCCTCCTGCACCGCGGCACGGAGAAATTGATAGAGTACAAGACTTACTTACAGGCTCTTCCATACTTCGACAGGCTCGACTATGTGTCCATGATGTGTAATGAGCAAGCATATTCTCTAGCCGTCGAAAAGCTTCTTAACATTCAGGCTCCACCTCGTGCACAGTGGATCCGAGTGCTGTTTGGAGAAATGACCCGTATCATGAATCACATCATGGGCATCACCACTCATGCCCTTGACATCGGAGCCATGACCCCCTTCTTTTGGATGTTTGAGGAGAGAGAGAAGTTGTTTGAGTTCTATGAGCGCGTGTCTGGAGCCAgaatgcatgctgcatatgtcaGACCCGGTGGAGTTCATCAGGACATGCCTCTTGGTCTCATGGATGACATCTATGAGTGGTGCAAGAATTTCTCTATTCGCATTGATGAAGTTGAAGAGATGCTGACCAATAATCGTATCTGGAAGAACAGAACTGTTGGTATTGGTGTCATTGGCGCTGAGGAGGCACTTAATTATGGCTTCAGTGGAGTGATGCTCAGGGGATCAGGCATTAAATGGGATCTGAGGAAGAGTCAACCATATGACAAATACGATGAGGTGGAGTTTGATATGGCCATTGGAACAAATGGTGACTGCTACGACAGATATCTGTGTCGAGTGGAGGAAATGAGACAGTCTCTACGTATCATGCATCAGTGTCTCAACAAAATGCCTCCTGGCGAGATTAAGGTTGATGACGCTAAAATAGCCCCGCCAAAGAGATCTGAGATGAAGACGTCAATGGAGTCTCTGATCCATCACTTCAAGCTGTACACTGAGGGCTATCAGGTTCCTCCAGGAGCTACATACACTGCTATAGAGGCACCCAAGGGGGAGTTTGGTGTGTATCTGGTGTCTGACGGCTCCAGCAGGCCTTACCGCTGCAAGATTAAAGCACCCGGCTTTGCACACTTgGCTGGTTTAGACAGAATGTCTCAAGGACACATGCTTGCTGATGTGGTGGCGATCATCGGCACTCAGGACATCGTGTTCGGTGAAGTGGACCGTTAAAGACGACAATGGCTGATCCTCCTTCTGTCTTTAATCCATTCTAGTGATATCACGACAGACCTTTCTCTCATTTCTCTATGTAAACACTTCTGaaacctaaataaatattttaaaacttgaaAAGAAAA

Function

symbol description
ndufs2 Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Leigh disease; hypertrophic cardiomyopathy; inherited metabolic disorder; multiple sclerosis; and nuclear type mitochondrial complex I deficiency 6. Orthologous to human NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2).

GO:

id name namespace
GO:0006120 mitochondrial electron transport, NADH to ubiquinone biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0005747 mitochondrial respiratory chain complex I cellular_component
GO:0008137 NADH dehydrogenase (ubiquinone) activity molecular_function
GO:0051287 NAD binding molecular_function
GO:0048038 quinone binding molecular_function
GO:0016651 oxidoreductase activity, acting on NAD(P)H molecular_function

KEGG:

id description
ko00190 Oxidative phosphorylation
ko04723 Retrograde endocannabinoid signaling
ko04714 Thermogenesis
ko05208 Chemical carcinogenesis - reactive oxygen species
ko05010 Alzheimer disease
ko05012 Parkinson disease
ko05014 Amyotrophic lateral sclerosis
ko05016 Huntington disease
ko05020 Prion disease
ko05022 Pathways of neurodegeneration - multiple diseases
ko05415 Diabetic cardiomyopathy
ko04932 Non-alcoholic fatty liver disease

ZFIN:

id description
ZDB-GENE-050522-273 Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Leigh disease; hypertrophic cardiomyopathy; inherited metabolic disorder; multiple sclerosis; and nuclear type mitochondrial complex I deficiency 6. Orthologous to human NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2).

Ensembl:

ensembl_id ENSDARG00000007526

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00067430 True 1593 mRNA 0.49 14 19043750 19068539

Neighbor

gene id symbol gene type direction distance location
XLOC_034634 fcer1g coding downstream 349 19033883 ~ 19043401 (-)
XLOC_034633 CU972454.4 coding downstream 14213 19028827 ~ 19029537 (-)
XLOC_034632 NA coding downstream 27863 19007755 ~ 19015887 (-)
XLOC_034631 NA coding downstream 40217 18990918 ~ 19003533 (-)
XLOC_034630 NA coding downstream 123765 18915542 ~ 18919985 (-)
XLOC_034636 kirrel1a coding upstream 1925 19070464 ~ 19146926 (-)
XLOC_034637 il13ra1 coding upstream 84781 19153320 ~ 19168375 (-)
XLOC_034638 dock11 coding upstream 111280 19179819 ~ 19332421 (-)
XLOC_034639 ntn4 coding upstream 265775 19334314 ~ 19369002 (-)
XLOC_034640 si:ch73-71d17.2 coding upstream 328590 19397129 ~ 19420334 (-)
XLOC_034628 NA non-coding downstream 269803 18762947 ~ 18773947 (-)
XLOC_034641 NA non-coding upstream 431441 19499980 ~ 19505267 (-)
XLOC_034652 CR339062.2 non-coding upstream 887539 19956078 ~ 19956192 (-)
XLOC_034654 NA non-coding upstream 976848 20045387 ~ 20050795 (-)
XLOC_034656 BX322601.1 non-coding upstream 1063797 20132336 ~ 20133863 (-)
XLOC_034657 NA non-coding upstream 1165875 20234414 ~ 20239135 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000344_00960146_00977733 NDUFS2, NDUFS2.L coding CI01000344 null 960027 ~ 979452 (-)