XLOC_003559 (egln1b)


Basic Information

Item Value
gene id XLOC_003559
gene name egln1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 31558006 ~ 31603692 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00006963
CATTTAAGTAATTTATATGgcaattatagatttttttagttGATTTTAATTCTGCCAACACAAAGTTATGAGAAGCACATGCGAGCCATGCCCACAATGCTTGCCTCTAGTGCGCATGCGCAGATGGTTGACGTGCGCCCAGCGCTGAAGAAAAGGAACGGTCGGCGCCATGCGCTTCCATCACAATCACACGACTTCAGTTCTAAAGTGTCAAAACATAGATGTCCCGGGAATGTGAGATCCTCGCTGTCCCCTCCGTCAACTGTTATGAGAACGGCAGCGGGGGGCCAGCGACACTGTTTGTTTCGTTTTCGCTTGTGGAGACTTGTAGTGAAGTTGCAGCCTGATACTGTAATACAGCGCTGAATCATGGAGGGAAACTCAAGGGAAAGCGAGCGTCTGGAGCGCGAGCGTCAGTTCTGTGAGCTGTGCGGGAAAATGGAGAACCTGATGAAGTGTGGACGCTGTCGCAGTTCGTTTTACTGCAGCAAAGAGCACCAGAGACAGGACTGGAAGAAGCACAAGCGGGTTTGCAAGGAGGCCGACAAACAGCAGCAGCCGGTgggtgaagaagaagaagagcagCCGAGCGACACTTCAAAACAGTCGAGCACTTCTCAGAGTAACTCTACACTTACGTCACAAGACGAAAAAATGCCAGATTTTATCAAGTCTGCTACAGGCTCTGACACCAAACCGACCCCGGACAGCTCAAAACCTAACGGACAGACGCGCTCCCCCCCTCAGAAACTGGCTACGGACTATATCGTGCCCTGCATGAACAAGCACGGCATCTGTGTGGTCGACAACTTCCTAGGGAACGAGGTCGGACGCAGTATTCTGGAGGACGTGCGGGCGCTTTATCTGACCGGCGGCTTTACGGACGGACAGCTGGTCAGTCAGAGGAGCGACTCGTCGAAGGACATTCGCGGGGATAAGATCACCTGGGTGGAGGGGAAGGAGCCCGGCTGTGAGCGGATAGCGTTTCTCATGAGCCGCATGGACGATCTGATCCGACACTGTAACGGGAAACTGGGCAACTACAGGATCAATGGAAGAACGAAAgcaATGGTGGCATGTTACCCTGGGAATGGGACAGGATATGTAAGGCATGTGGATAACCCTAATGGAGATGGGAGATGTGTCACATGCATATATTACCTGAATAAAGACTGGGATGCCAcgGAACATGGTGGCCTTTTGCGGATCTTTCCAGAGGGAACAGCTCAGTTTGCAGACATTGAACCCAAGTTTGACAGACTTTTGCTGTTCTGGTCAGACAGAAGGAACCCGCATGAGGTCCAGCCAGCTTATGCCACAAGGTATGCTATAACGGTGTGGTATTTTGATGCTGATGAGCGAGCTCGAGCTAAAGAGAAATATTCAACAAGTTCAGGAGAAAGGGGTGTAAAAGTGGAACTAAACAAGCCATCTGAGCCGAGCTAGTGATCATGGAGGACTGAATGAAGTGGAGTGACTGCCGGGGTCAGACCTGCTGCTGAGAGATGATGAAAGTGAAGAAGAGGAAGACCATCATGAAATCACTTCCTCTACGCTTCACCTCTCCATCCATCATCTACAATGGGGCTTCTCATAAAGACTCGGACTGTGATAGAGCTGCGAAAGACAGACGTGCATTAATACATGCTTTGTGTTTCCTTAATGAAGAAAGCTGGCTTACATGAGCATTACATGGACAAAGCGCTAAacctgtgtgtgtttgcgcatTCCCATTCAATACAGGTTTATTTTTGAGCTACGACTCCTCCAGTTTCCCTCGTCAGCTTTGCACATTCGTTAATAAAGGTACATTTATGTTTGTCAAGTGCATACTCGGAAAAATAAGCTGTCCGTTCGGTGTTATTCTGCTCATAAGCCACTGTAATGATCAGGTTTGTGTTTATCGTATGGTTGTATTTCCAGGCTCTTCTTAATTGGAGTTTTCCGGAACGTGCTTCTTTCTTTATCATGGCTTGCCACCTGTTTGCGTTGTTAATCGGGGTGCCATGGCTGGATTGTTTTTTGCAAGTAAATCTGCGTTATGTCTGTTGTTGCAGACGTCATGTCCCTACTGTCGTAAGCCAAAATTGACACCTAATGTCTGTCTAACAGCTCTGAGTTTTAATTAAAGAAGCAGTTTTCCTAAATATATCTTGTTTTGGATGGTTGTGAGTGTTACGTTATTATCTGTACTCTCTTTTTGGAGGGGTTTGTTTCGAGTCCTGCAGCACCCTCTAGCGGTTGGcagcagcaaatgcagtttttatcaTGAATATTGTCACCATGAACCGTTTGACCATGCAAAAGCcctaatttgtgtgtgtgtgtgtgtgtg
>TCONS_00006964
TCTAAAGTGTCAAAACATAGATGTCCCGGGAATGTGAGATCCTCGCTGTCCCCTCCGTCAACTGTTATGAGAACGGCAGCGGGGGGCCAGCGACACTGTTTGTTTCGTTTTCGCTTGTGGAGACTTGTAGTGAAGTTGCAGCCTGATACTGTAATACAGCGCTGAATCATGGAGGGAAACTCAAGGGAAAGCGAGCGTCTGGAGCGCGAGCGTCAGTTCTGTGAGCTGTGCGGGAAAATGGAGAACCTGATGAAGTGTGGACGCTGTCGCAGTTCGTTTTACTGCAGCAAAGAGCACCAGAGACAGGACTGGAAGAAGCACAAGCGGGTTTGCAAGGAGGCCGACAAACAGCAGCAGCCGGTgggtgaagaagaagaagagcagCCGAGCGACACTTCAAAACAGTCGAGCACTTCTCAGAGTAACTCTACACTTACGTCACAAGACGAAAAAATGCCAGATTTTATCAAGTCTGCTACAGGCTCTGACACCAAACCGACCCCGGACAGCTCAAAACCTAACGGACAGACGCGCTCCCCCCCTCAGAAACTGGCTACGGACTATATCGTGCCCTGCATGAACAAGCACGGCATCTGTGTGGTCGACAACTTCCTAGGGAACGAGGTCGGACGCAGTATTCTGGAGGACGTGCGGGCGCTTTATCTGACCGGCGGCTTTACGGACGGACAGCTGGTCAGTCAGAGGAGCGACTCGTCGAAGGACATTCGCGGGGATAAGATCACCTGGGTGGAGGGGAAGGAGCCCGGCTGTGAGCGGATAGCGTTTCTCATGAGCCGCATGGACGATCTGATCCGACACTGTAACGGGAAACTGGGCAACTACAGGATCAATGGAAGAACGAAA

Function

symbol description
egln1b Predicted to enable ferrous iron binding activity and peptidyl-proline 4-dioxygenase activity. Predicted to be involved in cellular response to hypoxia and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in familial erythrocytosis 3; polycythemia; and renal cell carcinoma. Orthologous to human EGLN1 (egl-9 family hypoxia inducible factor 1).

GO:

id name namespace
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0071456 cellular response to hypoxia biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0005506 iron ion binding molecular_function
GO:0031543 peptidyl-proline dioxygenase activity molecular_function
GO:0031545 peptidyl-proline 4-dioxygenase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0008198 ferrous iron binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0031418 L-ascorbic acid binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040718-338 Predicted to enable ferrous iron binding activity and peptidyl-proline 4-dioxygenase activity. Predicted to be involved in cellular response to hypoxia and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in familial erythrocytosis 3; polycythemia; and renal cell carcinoma. Orthologous to human EGLN1 (egl-9 family hypoxia inducible factor 1).

Ensembl:

ensembl_id ENSDARG00000004632 ENSDARG00000105156

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00006963 False 2335 mRNA 0.48 5 31558006 31603692
TCONS_00006964 True 864 mRNA 0.54 1 31558207 31559070

Neighbor

gene id symbol gene type direction distance location
XLOC_003558 sipa1l2 coding upstream 84024 31323746 ~ 31473982 (+)
XLOC_003557 NA coding upstream 237467 31284984 ~ 31320539 (+)
XLOC_003556 trmt1 coding upstream 299650 31236001 ~ 31258356 (+)
XLOC_003554 NA coding upstream 345237 31204986 ~ 31212769 (+)
XLOC_003555 NA coding upstream 348119 31205483 ~ 31209887 (+)
XLOC_003560 zgc:162816 coding downstream 5789 31609481 ~ 31621674 (+)
XLOC_003561 NA coding downstream 21479 31625171 ~ 31671413 (+)
XLOC_003562 diaph3 coding downstream 76821 31680513 ~ 32155212 (+)
XLOC_003563 AL844172.1 coding downstream 236376 31840068 ~ 31840189 (+)
XLOC_003564 CR556714.1 coding downstream 319419 31923111 ~ 31923225 (+)
XLOC_003369 CR854846.2 misc upstream 15434924 16122786 ~ 16123082 (+)
XLOC_003318 CR450764.6 misc upstream 18846010 12711700 ~ 12711996 (+)
XLOC_003317 CR450764.16 misc upstream 18863743 12693967 ~ 12694263 (+)
XLOC_003316 CR450764.11 misc upstream 18872407 12685304 ~ 12685599 (+)
XLOC_003315 CR450764.18 misc upstream 18877978 12679732 ~ 12680028 (+)
XLOC_003551 CR855274.2 non-coding upstream 502718 31047854 ~ 31055288 (+)
XLOC_003550 CR855274.1 non-coding upstream 583114 30974771 ~ 30974892 (+)
XLOC_003565 CR556714.2 non-coding downstream 382236 31985928 ~ 31986044 (+)
XLOC_003566 CABZ01011390.1 non-coding downstream 588065 32191757 ~ 32191871 (+)

Expression


Co-expression Network