XLOC_004677 (hbae5)


Basic Information

Item Value
gene id XLOC_004677
gene name hbae5
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 20342451 ~ 20353541 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00009262
CTACACTTTAGCTAAaatgaggaagaggaagaggtCTACAAGTCGCAGCAAATGAAGAAGAACATGCGGGCGAAATAAGGGGATTCACTTGACAAGTGCACTGGATAATGgacaacagcattGACTCCCGAAGATAAAGGACTACCAGAGACAACAACAGCGAGGAACTTCTGCCAGGCAGCCTGCATGTCGGCTGTGAAAGCGGCGCCCATGGTGGAGGCAATCACGATTGTCAGGCAGTCGGCCAGCAGCTGAAACAGAGGAAAACAAACGGAACAGattGCTTTTGGTGTACCCTCAGACCAAGACCTACTTCTCCCACTGGAACGATCTGGCCCCCGGCTCTCCCTCTGTGAAGAAGCAGGGAAAGAAGATCGTCGGTGGACTCGGTCTGGCTGTTGATAAAATCGACGACCTTTTCAACGGCCTGCTGAACCTCAGTGAATTGCACGCCTTTCAGCTGAGAGTCGACCCTGCTAACTTCAAGCTCCTGTCTCACTGTCTGCTGGTGGTGTTCGCCATGCTCTTCCCTGATGACTTCACCGCTGAGGTCCATCTGGCCATCGACAAGTTCCTGGCAAGAGTGGCTTTGGCTCTGTCTGACAAATATCGTTAACTCTTCTGTTTAACAGCATGAACGTGGTTTTGTCGATATGGTCAACAgcatgtcaataaaaacaaacctAAAACCACT
>TCONS_00009263
GTCTTTGGCTGGGAAACCCCATTTGAAAGAAGAAGAACATGCGGGCGAAATAAGGGGATTCACTTGACAAGTGCACTGGATAATGgacaacagcattGACTCCCGAAGATAAAGGACTACCAGTCTTTTCACTCTGAGAATGATCAAGGGACTCAAACAAACCTATTAAAAAGAGTGAAAAGATGAATCTGACAATCTTACAGTCACTGCTAAAAAGGGTTCAAATCTGCTGAAGATGAAGAAAACTGAAGAATCTGCAGGACatggatgattttttttctaaagaccAGCAGTCAGTTTAACTGTTCAGAACAAACAAGAGACTCATAAACAACCACCATAAAGTAGAAAAGCCAAGGgtTTAAGATGACTATAATTTTATAACCAATCAAGAGCACCCCAGTTCACTTGTTTCCAACATCTTTGTGGACAACCAATCCAGTGATGAAGGTCACAAGAAAGCTGAAATATAGCCATAGAGAGAGCAAATGTACTTTTTGGAGCCGATTCTTGCACCTACTGTACCTAATGGGCCGCATTTATGCACTGGAACTAAGCTATCCAAAGAAACTCAAATACAACTTTGAGGTCTTTCATAAGGGCTTCTTCAAGCTTGACGACGAACAGTAACATGCTCCCCAACGTCCACAATCTCAAGGTCAGCTTATTGACCTAAAAGCCATACAGACATTGTTGATGCTAGCGAGATTTTGTTGGGTAATTTCAGTTAAACTGTATTGTTCAGATTCATCAGGTTTACCAAAAGCACATTTTTGAAATGGTATTTTTATATTTGGATCATACTAGTGTGtcagttaaagggttagttcact
>TCONS_00010917
GGGAAACCCCATTTGAAAGAAGAAGAACATGCGGGCGAAATAAGGTAAGGATCAAGTGTTTAAAGTTAGTTATAGGTTCATTAACATTTGTTTCACAACAGTTTTGACATTGTACAGAAACAAAGACAAACTGTAAATTTACTGTGCTGTGACAACTGCGCTTTATATGGATTTCCTAACATAAACGGGAAGCTGGTATGTGGCAGTTAATTGCTGCATGTGCTAATGCAAATGGCGGATTTGTTCTTACTCTAAGTTGACACTTTTGCAAATCTGACTATGAAATAATGCATGTAGTGTAAAATAATGTTAGATTGTATTTTTAGGACAGGATTAGTATTTAGATTCTTTCAGTTTAACCTCTTTACACAAGAAGCTAGCTTCAATATTTGAACAGACTGTTTATGTTGCATGTTGCAGTGacattaatttcttaatttatgtCAAGAGTCCAAAATAACTAATCATTATTTTATCTTCAATGGAAAAAAAACGAGTAGGCCTACATAATATTTGTATGCAACTATATGCTTCAATTTATTTCTGCTTGCGTAGCTGCACTGATGGCATCTGTTAGAACAAAAATGTACATGTTTGGAGAAACACTGATTCATTCTCACGTTTGTAAAATATTCTGTCAAGATACGGTTTTATGttctttaacttaaattacatgtAAAGGGCTTTTCAGAGAAGCTCTCCTTGGTCTTAAGCCCTATTTTCAAACATTATTAACAGGCAAGATAATGATAAAAATCATGTTAGTTATTATGCATGCCAGGCTAGCAAATTgaagtataataataaaagtgcCTTAGATACCCAGTGCTAGTTTCAGCATCTTTGTTCTCTCCTTTAAAAAATGCTgagaaaaatgtttgtttttatttcactacATTTTTAGATAACGATTTAAAAAACTTACTAGTTAAACTAATTGCCCTGGATTTGTGCATTGGTCAGTTAATAATCATTACACACTCTCCCCAACAGGGGATTCACTTGACAAGTGCACTGGATAATGGTATGTAATGTTCAAGAAATTGGTTTATTGTGTTAACTGTTTATAAGCTGATTGCAGTGCATTAAATTCACATTTGGAGAGGTAAAAGATAAGTTAATGGTGACAATTTTAATATgtcatattatatatttttaggacaacagcattGACTCCCGAAGATAAAGGACTACCAGGTAaaggaacattttttatatatattcatgtGAAAACTTTAAACAAGTGAGATCATAcaaaatgcatgttatttttttatttaatactgttTAATACTGTTTTGAGATGTTTACATACAGTATAGTTCAAAATACAAAAACCTAGCTCAAAATATTAAATTAGCCCCCTGCAAAAGTTTacctacattatttttttaatatggtttGGGGTTTTCTGATGATCCACTAGTGTCTTTTCTGCTTTTTGATGGATCAGTCTTATGTTTGTACTGAAAAGTTAAACTCCTCTGAAAAGTTAAATTCTACATGTTCTGCACATTCTTCAGTTTTTTTAGCATCTTCTATAGATTTGAACCCTTTCCAGCAGTGATCGTATGATTGTGAGATTTGTCTTTCAGTCTTTTCACTCTGAGAATGATCAAGGGACTCAAACAAACCTATTAAAAAGGTAGCTTTTGATGCTCCATGATGCTCCAGAAATAAATGCAAGGCACTAAGAGCCGGGcggtaaaaacatttataatcaaAATATTAAGGTAAATTGCAATTTGCCTTTTAGGAAATATGcaagtattttctgttttttttaagtaaaatatgacatttcaaaatgatgtttcaacaaaataaaaaaatgacatgttCCTCCTGTTTAAAAGTTTTCACCCCCTGGTTCTTAATTCCATGTGATTCCTTCTGAAACGTCAgttaacatttaaacctttttaacaGTTATGTTTATGTCCCTTAATCATCCTCAGAGTGAAAAGATGAATCTGACAATCTTACAGTCACTGCTAAAAAGGGTTCAAATCTGCTGAAGATGAAGAAAACTGAAGAATCTGCAGGACatggatgattttttttctaaagaccAGCAGTCAGTTTAACTGTTCAGAACAAACAAGAGACTCATAAACAACCACCATAAAGTAGAAAAGCCAAGGGTGAGTAAACGTTTGCAGGGGGCTGCTCAGAGGAACAGCAAATGTGCATTATTTACATCAGCAAATATACatgagatttttaattatttctggatttttttgtttgttttgttttacaggtTTAAGATGACTATAATTTTATAACCAATCAAGAGCACCCCAGTTCACTTGTTTCCAACATCTTTGTGGACAACCAATCCAGTGATGAAGGTCACAAGAAAGCTGAAATATAGCCATAGAGAGAGCAAATGTACTTTTTGGAGCCGATTCTTGCACCTACTGTACCTAATGGGCCGCATTTATGCACTGGAACTAAGCTATCCAAAGAAACTCAAATACAACTTTGAGGTCTTTCATAAGGGCTTCTTCAAGCTTGACGACGAACAGTAACATGCTCCCCAACGTCCACAATCTCAAGGTCAGCTTATTGACCTAAAAGCCATACAGACATTGTTGATGCTAGCGAGATTTTGTTGGGTAATTTCAGTTAAACTGTATTGTTCAGATTCATCAGGTTTACCAAAAGCACATTTTTGAAATGGTATTTTTATATTTGGATCATACTAGTGTGtcagttaaagggttagttcact
>TCONS_00009264
CGTGTCCGCTCAACCACAAACGCTTAAAAAGAGGAGCAACATGTAGGTGCCCAGTCTGATCATCCCAGACATCGATTCAAAATGAGTCTTTCTGCTAAAGACAAGGCCGCCGTGAGGGGCTTCTGGGCCAAGATTGCCCCAAAGGGAGAGCAAATTGGTAACGAGGCGTTTTCCAGattGCTTTTGGTGTACCCTCAGACCAAGACCTACTTCTCCCACTGGAACGATCTGGCCCCCGGCTCTCCCTCTGTGAAGAAGCAGGGAAAGAAGATCGTCGGTGGACTCGGTCTGGCTGTTGATAAAATCGACGACCTTTTCAACGGCCTGCTGAACCTCAGTGAATTGCACGCCTTTCAGCTGAGAGTCGACCCTGCTAACTTCAAGCTCCTGTCTCACTGTCTGCTGGTGGTGTTCGCCATGCTCTTCCCTGATGACTTCACCGCTGAGGTCCATCTGGCCATCGACAAGTTCCTGGCAAGAGTGGCTTTGGCTCTGTCTGACAAATATCGTTAACTCTTCTGTTTAACAGCATGAACGTGGTTTTGTCGATATGGTCAACAgcatgtcaataaaaacaaacctAAA

Function

symbol description
hbae5 Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to act upstream of or within oxygen transport. Predicted to be part of haptoglobin-hemoglobin complex and hemoglobin complex. Is expressed in intermediate cell mass of mesoderm and vasculature. Human ortholog(s) of this gene implicated in Heinz body anemia; alpha thalassemia; familial erythrocytosis 7; and hemoglobin H disease. Orthologous to several human genes including HBZ (hemoglobin subunit zeta).

GO:

id name namespace
GO:0042744 hydrogen peroxide catabolic process biological_process
GO:0015671 oxygen transport biological_process
GO:0031838 haptoglobin-hemoglobin complex cellular_component
GO:0005833 hemoglobin complex cellular_component
GO:0005506 iron ion binding molecular_function
GO:0019825 oxygen binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004601 peroxidase activity molecular_function
GO:0043177 organic acid binding molecular_function
GO:0005344 oxygen carrier activity molecular_function
GO:0031720 haptoglobin binding molecular_function
GO:0020037 heme binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-101028-1 Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to act upstream of or within oxygen transport. Predicted to be part of haptoglobin-hemoglobin complex and hemoglobin complex. Is expressed in intermediate cell mass of mesoderm and vasculature. Human ortholog(s) of this gene implicated in Heinz body anemia; alpha thalassemia; familial erythrocytosis 7; and hemoglobin H disease. Orthologous to several human genes including HBZ (hemoglobin subunit zeta).

Ensembl:

ensembl_id ENSDARG00000045142

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00009262 False 694 mRNA 0.50 7 20342451 20353541
TCONS_00009263 False 833 lncRNA 0.39 6 20343889 20346635
TCONS_00010917 False 2737 lncRNA 0.33 1 20343899 20346635
TCONS_00009264 True 585 mRNA 0.50 3 20352400 20353535

Neighbor

gene id symbol gene type direction distance location
XLOC_004676 zgc:163057 coding upstream 5177 20336070 ~ 20337274 (+)
XLOC_004675 NA coding upstream 76986 20263585 ~ 20265465 (+)
XLOC_004674 mgrn1a coding upstream 185437 20122256 ~ 20157014 (+)
XLOC_004673 mrtfba coding upstream 297350 19976400 ~ 20045101 (+)
XLOC_004672 ercc4 coding upstream 367078 19958845 ~ 19975373 (+)
XLOC_004678 arhgap17a coding downstream 58752 20412293 ~ 20482061 (+)
XLOC_004679 NA coding downstream 138078 20491619 ~ 20504801 (+)
XLOC_004680 si:zfos-754c12.2 coding downstream 152656 20506197 ~ 20508359 (+)
XLOC_004681 gna13a coding downstream 198649 20552190 ~ 20564678 (+)
XLOC_004682 AMZ2 coding downstream 213841 20567382 ~ 20575381 (+)
XLOC_004670 NA non-coding upstream 883166 19458809 ~ 19459285 (+)
XLOC_004667 BX649366.2 non-coding upstream 954178 19388143 ~ 19388273 (+)
XLOC_004660 NA non-coding upstream 1071295 19267759 ~ 19271156 (+)
XLOC_004648 NA non-coding upstream 1474476 18861278 ~ 18867975 (+)
XLOC_004689 NA non-coding downstream 453356 20806897 ~ 21106987 (+)
XLOC_004691 FO704814.1 non-coding downstream 1083805 21437346 ~ 21437458 (+)
XLOC_004694 NA non-coding downstream 1404276 21757817 ~ 21799396 (+)
XLOC_004695 NA non-coding downstream 1664405 22017946 ~ 22019770 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00018369 NA misc CM030135.1 CM030135.1 9480952 ~ 9486146 (+)