psen1 (psen1,LOC100697238)


Basic Information

Item Value
gene id psen1
gene name psen1,LOC100697238
gene type misc
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053131.1
NCBI id CM020928.1
chromosome length 36057207
location 9591170 ~ 9604625 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>TU272658
GGATGTTCTGTGTGAAGACAGGAACAACAAAGAAGAGAAAGCGCCCGGGTTTTAAAACTAATGAGAACACACCAGAACACACAATCAAGAAAATTAGCTGTCGTTGACAGGCAAAAGCATTTGGTTTGCATGTGAGAAAAAGTGTCTGCCGAGCCAACCATGGCGAACAATGCAGAGGACATTGAAAACAATATGgaCCACCAGGAGACCAGTGTGGCCTGTGAACCCAGCCAGCAGCCACAGGAGGCTGCGGTGGTCAGA
>XM_039785407.1
TTACAGCAGCGGCCGGATGTTCTGTGTGAAGACAGGAACAACAAAGAAGAGAAAGCGCCCGGGTTTTAAAACTAATGAGAACACACCAGAACACACAATCAAGAAAATTAGCTGTCGTTGACAGTAGGGCAAAAGCATTTGGTTTGCATGTGAGAAAAAGTGTCTGCCGAGCCAACCATGGCGAACAATGCAGAGGACATTGAAAACAATATGgaCCACCAGGAGACCAGTGTGGCCTGTGAACCCAGCCAGCAGCCACAGGAGGCTGCGGTGGTCAGAAGCCAGTCAAAGGGCGCCCCCCGGGGGGGCGTTCCCGTGATCTACACACCATTCCctgaagacacagacacagtagGACAGAGAGCCATCAACTCCATCCTGAACGCCACCATCATGATCACTGTGATCATCGTCATGACACTGGTGCTGGTGCTGTTATACAAGTACCGCTGCTACAAGGTGATCCAAGGCtggctcttcctctcctccctcctcctgctGTTCTTCTTCTCCTACATCTACCTCAAAGAGGTTTTCAAGACCTACAATGTGGCCATGGACTACTTCACCCTGGCGGTAATCATTTGGAACTTCGGAGTGGTGGGCATGGTCTGTATTCATTGGAAAGGGCCGCTGCGGCTCCAGCAGGCCTACCTCATCATGATCAGCGCCCTCATGGCCCTGGTTTTCATCAAGTACTTGCCGGAGTGGACCGCCTGGCTCATATTAGCCGTCATATCCGTCTACGATCTGTTAGCGGTTCTCTGTCCCAAAGGGCCTCTGAGGATCCTGGTGGAGACGGCTCAGGAGAGGAACGAGCCCATCTTTCCAGCTCTCATCTACTCCTCTACAATGGTGTGGCTCGTTAACATGGCCGACACCGACCGGCCAAAAAGGAACTCGACGGAAGCGGCGTCATCTCAACAAGGCGCTCACGAAGCCGTGGCGTCCCCGGCTGCCGCCAGTCCGCCGCAGGACGACGGGGGCTTCACCTCCACCTGGGTCAACCAGCAGGAGCACCAGCTGGGGCCGCTCCAGTCCACCGAGCAGACCAGACGGGAGATCCAGGAGATGCCCTCCGCTCGCCCTCCCGCCGAAGACGACGATGAAGAGAGGGGCGTCAAACTGGGACTGGGAGACTTCATCTTCTACAGCATGCTGGTGGGAAAGGCCTCGGCCACGGCCAGCGGCGACTGGAACACCACGCTCGCCTGCTTCGTAGCCATCCTCATCGGCCTGTGCCTCACCCTGCTGCTCCTCGCCATCTTCAAGAAAGCGCTCCCCGCTCTGCCCATCTCCATTTTTTTCGGCCTGGTCTTCTATTTCGCCACAGACAACCTGGTGCAGCCCTTCATGGACCGGCTGGCGCTACACCAGTTCTACATTTAGCAGCACGCTGCCCTGATAACCCTCACCCACGTAGCCCTCTGGCCAACAACACGAGAGCAGTCCCTTCACAGCTGGGGGTGGTGGAGAGGGGGCGGTGGGGGACAAAGGGCGATGCAGGCCAGGGGCCTCTCCCACCCCCACATCCCCTCCTAAGAACTCCCGATGACGGGAAACAAGTTGTTTctgttctgcctttttttttctttatcgaCGCCAA

Function

symbol description
psen1 Predicted to enable aspartic endopeptidase activity, intramembrane cleaving; beta-catenin binding activity; and cadherin binding activity. Acts upstream of or within several processes, including amyloid-beta formation; cell surface receptor signaling pathway; and optomotor response. Is intrinsic component of membrane. Is expressed in blastomere; brain; female organism; heart; and male organism. Used to study Alzheimer's disease and Alzheimer's disease 3. Human ortholog(s) of this gene implicated in Alzheimer's disease (multiple); Pick's disease; dilated cardiomyopathy 1U; frontotemporal dementia; and hidradenitis suppurativa. Orthologous to human PSEN1 (presenilin 1).

NR:

description
presenilin-1-like

GO:

id name namespace
GO:0008152 metabolic process biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0016021 integral component of membrane cellular_component
GO:0004190 aspartic-type endopeptidase activity molecular_function

KEGG:

id description
K04505 PSEN1, PS1; presenilin 1

RNA

RNA id representative length rna type GC content exon number start site end site
TU272658 False 261 lncRNA 0.48 3 9591184 9597003
XM_039785407.1 True 1606 mRNA 0.57 11 9591170 9604625

Neighbor

gene id symbol gene type direction distance location
exd2 exd2 coding upstream 28602 9553606 ~ 9562568 (+)
numb numb coding upstream 38320 9501661 ~ 9552850 (+)
galnt16 galnt16,LOC102792495 coding upstream 93632 9442548 ~ 9497538 (+)
vps39 vps39 coding upstream 160123 9393774 ~ 9431047 (+)
LOC120549640 tmem87a coding upstream 199704 9371102 ~ 9391466 (+)
paplna papln,LOC102790008 coding downstream 10935 9615560 ~ 9653399 (+)
LOC120549788 LOC104935424,LOC103365743,LOC103381674 coding downstream 409099 10013724 ~ 10024172 (+)
LOC120549541 NA coding downstream 425371 10029996 ~ 10034827 (+)
LOC120549542 NA coding downstream 425935 10030560 ~ 10031384 (+)
LOC120548903 NA coding downstream 435518 10040143 ~ 10040762 (+)
G201246 erh,LOC100699790,LOC101174968,LOC105904210,LOC101161113 non-coding upstream 386 9586960 ~ 9590784 (+)
G201239 NA non-coding upstream 92387 9498496 ~ 9498783 (+)
G201173 NA non-coding upstream 247177 9336645 ~ 9343993 (+)
G201175 NA non-coding upstream 260337 9329485 ~ 9330833 (+)
G201134 NA non-coding upstream 317193 9268917 ~ 9273977 (+)
G201309 NA non-coding downstream 227012 9831637 ~ 9856727 (+)
G201314 NA non-coding downstream 301872 9906497 ~ 9906866 (+)
G201396 NA non-coding downstream 489766 10094391 ~ 10094751 (+)
G201409 NA non-coding downstream 547276 10151901 ~ 10152759 (+)
G201480 NA non-coding downstream 668447 10273072 ~ 10295497 (+)
G201057 dcaf10,LOC102795877 other upstream 369868 9220641 ~ 9221302 (+)
LOC120550068 NA other upstream 2690826 6900139 ~ 6900344 (+)
LOC120549783 NA other upstream 2822508 6758637 ~ 6768662 (+)
vps29 eif5,vps29,LOC107595689 other upstream 2843768 6732248 ~ 6747402 (+)
G200492 NA other upstream 2908579 6677658 ~ 6682591 (+)
G201287 NA other downstream 104239 9708864 ~ 9817625 (+)
smoc1 smoc1 other downstream 331111 9935736 ~ 10007687 (+)
LOC120549492 NA other downstream 437400 10042025 ~ 10044094 (+)
LOC120549595 NA other downstream 444886 10049511 ~ 10050146 (+)
LOC120548905 NA other downstream 445623 10050248 ~ 10050943 (+)

Expression


Co-expression Network