XLOC_005183 (adam8b)


Basic Information

Item Value
gene id XLOC_005183
gene name adam8b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 9096963 ~ 9132682 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00010004
ATGCCGTGTCCTGCCTTCACAGCTCATATACTTTGCTGGCTTTGTCTTTGTGGATGTGTGGCAGAAAGTATCCGTACATTACCTCATGTTGAGCGTTTTGATGTGGTGAGACCTAAAAGACTGAACCTCAGTAAGGTACAGTCTGATAAAAATCCACCAAGCCATGAGAAGTATCCTGACAGACTCGCATATAAATTATTCTTTGAAGGAGAAAATCATGTGATTCACTTGGAAAAGAACAAGCAACTCGTTGGACATAATTACACTGAAATATACTATCAAGATGACGGATCAATTGTGAGCAGAAATCCAAGTTTTAAGgaCAATTGCTACTACCATGGGCACATTCAAGATATGGAATATTCCTCAGTCAGCGTGGGAATCTGTTCTGGGATCAgAGGTTTTGTCAGAGTGAAACAACAAGTCTATCTGATTGAGCCCCTAGCTAACCACAGTGATGGAGATCATGCACTTTATAAACACCAGCATCTGAGGAGAAGGAGAAGCTCTGCTGGTGAACCGAAAACCATGTTTTATGACCACGAACCACAAGTGAGCGCTGCCTTAAAGTCGAGCAGATGGAATATGAAGAGTTTTCAAACTCCAAGATTTGTGGAATTATTTCTGGTGGTCGATAACACTGAGTACAGAAACTTTGGCTCTAGCATGGATTCTATCAGAGCCAGGATGCTGGAGGTGGTAAATCACGTTGACAAGTTGTATCGATCTCTTAATATCCGAGTGATGTTGGTGGGTCTTGAGGTCTGGATGAAACAGGACCAGATTGTGGTCAGTGTGAGTTCTGATGACACTCTCAGTCGCTTTATAGAATGGAGGAAGAGCAATCTGCTTAAAAGGGTCAAACATGACAACGCTCAGTTTGTGACtGGAATTGATTTTTTGGGTGACACAGTTGGGTTGGCAAACAAATTTGCAATGTGTGCCGAAAGCTCAGCAGGAGTCAATCAGGATCATAATCAGAACCCACTGGGCCTGGCATCCACAATTGCACATGAGATGGGTCATAACATGGGCATGTCCCATGATGAGGATCACTGCACGTGTGGCTCGTCAGTGATCAGTTCCTTCTGTATCATGACAGAGCGTGTGGGCACGCTGTTCCCAGAGCAGTTCAGTGACTGCAGTCTAGAGCAGCTGACTGTATTTCTAGACAACGCCAACCCTAGCTGTCTGCTGGACACCCCCAGCTCATACAAACTGTACAGTGGGCCTGTCTGTGGTAATGCTTTCCTGGACCCTGGAGAGGAGTGTGACTGTGGATCAGTGGAGGAATGTAAAAATCCATGCTGTGATCCCATGACCTGCAAGCTCACTGAAGGTTCACGCTGTGCTCAGGGAGACTGCTGTGAGAATTGCCAgATAAAAGATGCTGAAAGCTTGTGTCGAGCATCTATAAATGAGTGTGATGTTCCGGAGTACTGCACAGGGCTTTCGGAGAAGTGCCCTGAGAATGACTTCAGGATGAATGGCATACCTTGCAGCTCTGGCCAGGGTTACTGCTACAATGGCCAATGCCCCACTCATCTCCAGCACTGCCAAAGGCTTTGGGGAACAGGTGCCAAAGTGGCTCCTGACACATGCTTTTACCAGAACACATTAGGAAAAAATGATTCTCACTGTGGAAAAACCAAAGATGGCATCAGACCCTGTGCAAGAGAAAACATGTTTTGTGGAAAGATCTTTTGCAATGAAGGAAATGAATTCCCCGTTACTGGTCAGAAAGCGGTCATAGTAACATTAAGAGGACAGTGCAACGTAGCAGGGGACCAAACAGAGGAGGACGCGCTCAGCATGGTTCCAACTGGCACAAAATGTGGGCATAATAAGGTTTGCTATGATTATAAGTGCCAAGAATTGAACATTTATGGTAGCATTGAAGGCTGTTCACTGCAGTGCAATGGTCGAGGGATTTGtaatcataaaaaacaatgccaCTGTGATCCAGGCTGGGCACCACCTTACTGTAATGTCAAATATTCTGAATTGTCATCTGCAAAGACCATTGGCATCTCAGTAGCTGTTGCAGTCGCTGTGCTTGTGGTAATATGTGGAGCCGTGCTTtatcataaaaaaagaaaagccatcagCCGCCACAAGACGCAAACTCCAACTTCAGGGCAAACGAGTCTTCTTTTTGAGAACAACAGTGCCCAGAAGGACCGTCCTGAGATCAGTCAGCCTATATTCATGGGGACCACTGTATCTCAACCCTGCACCCCTCTAACTGCCAGAGTGGGTCCGACCCGTCCTGCTCCACTACCTCCAAAAAAGCCGCCATCACAACCCCAGCAGACCACAGTTACACAGGGAACGAAGTTGCCTGCACCTCCAGTTCCTCCAGTAAAACCATCTTTAGCAACAGGATCCTGGAGGAATGACCATGTGACAGAAGACACAGTGAAGGTTGTGTTGAAACCTCCCATCATGCCAAGAAGATGACCAGACCTGAAATCCCCCTGTGAGTCATTTCAGGAAATTAGAACCTTTCTCTGTCACTTTTATAGAGTGGGAGTGTCTGAATCACAAAGTGCTTTTTTTAAACCatgctttaaaaaacacacatacactgctgTGCTTGGCCTTAGCTGCGTGTTGTCTGTTAGTATatagttaaattaaaattattccccctcctgtgatttctttttttcttttttaaatatttctcaaagaatgtttaacagagcaaggatttttttttcatagtatttcctaaaatattttttcttctggagaaagtcttagttgttttatttcggctagaataaaagcagtttttaattttctttaaaaccattttaaggtcaatattattagcctctttatgctatatatttttcgattgtctacagggCAAATCACttttttacaatgacttgcctatttgaCCTAatctgcctagtaaacctaagtAGCCTAGTTAAgaatttaaattgcactttaagctgaatactagtatttagtaaaatattatatactgtcatcatgacaaagataaaataaatcagttattagaaatgagttattaaaactattatgttaagaaatgtgttgaaaaaaaatcttctctccattaaacagaaattggggaaaaaatatacagggggctaataattcaggatggctaataattctgattttaactaagtcaaaattattagcattattagctccccttttgattttttttctttgtttttaaatatttcctaaatgatgtttaacagagcaaggaaatgttcacagtatgtctaataatattttttcttctggagaaattcttatttgttttattttggcttgaataaaagaagtttttaattttgtaaaaactattttaaggtcaaaattattagcccctttaagctatattttttcctc
>TCONS_00010006
ttaactaatgcatttattaatgattatcGATTAATGCTTCGATATCGCAGTgtaatcattcgcaatagtcTCTGTGGCAAGGGGGCAGGGCCCAGAGCCGTGGGAACGTAATGAGACTGCTGTGTAAGTGGATTCACCTGTAGCGCGCACTGGTCTCGAATCCTaaggaaggagctctggactttaagaggaggaacgatggcaaaagtaaaacaatctgTTTGGGCCCGGTCCACTCTCGGGTTCCTCGGCCATCGTTcctcatctggtgaaattgtatttagattgcaatatatattgcaaaataaaaaaaaatctcaatatcgtgcagcccaactattaacagtttttttttttttcctctagtGGAATTGATTTTTTGGGTGACACAGTTGGGTTGGCAAACAAATTTGCAATGTGTGCCGAAAGCTCAGCAGGAGTCAATCAGGATCATAATCAGAACCCACTGGGCCTGGCATCCACAATTGCACATGAGATGGGTCATAACATGGGCATGTCCCATGATGAGGATCACTGCACGTGTGGCTCGTCAGTGATCAGTTCCTTCTGTATCATGACAGAGCGTGTGGGCACGCTGTTCCCAGAGCAGTTCAGTGACTGCAGTCTAGAGCAGCTGACTGTATTTCTAGACAACGCCAACCCTAGCTGTCTGCTGGACACCCCCAGCTCATACAAACTGTACAGTGGGCCTGTCTGTGGTAATGCTTTCCTGGACCCTGG

Function

symbol description
adam8b Predicted to enable cell adhesion molecule binding activity and metallopeptidase activity. Predicted to be involved in several processes, including inflammatory response; positive regulation of cellular extravasation; and positive regulation of membrane protein ectodomain proteolysis. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in ovarian follicle. Orthologous to human ADAM8 (ADAM metallopeptidase domain 8).

GO:

id name namespace
GO:0022407 regulation of cell-cell adhesion biological_process
GO:0006954 inflammatory response biological_process
GO:0006508 proteolysis biological_process
GO:0051044 positive regulation of membrane protein ectodomain proteolysis biological_process
GO:0002693 positive regulation of cellular extravasation biological_process
GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004222 metalloendopeptidase activity molecular_function
GO:0008237 metallopeptidase activity molecular_function
GO:0050839 cell adhesion molecule binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-070808-1 Predicted to enable cell adhesion molecule binding activity and metallopeptidase activity. Predicted to be involved in several processes, including inflammatory response; positive regulation of cellular extravasation; and positive regulation of membrane protein ectodomain proteolysis. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in ovarian follicle. Orthologous to human ADAM8 (ADAM metallopeptidase domain 8).

Ensembl:

ensembl_id ENSDARG00000057644

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00010004 False 3402 mRNA 0.41 23 9096963 9132682
TCONS_00010006 True 741 mRNA 0.47 3 9120766 9123352

Neighbor

gene id symbol gene type direction distance location
XLOC_005182 exoc6 coding downstream 9397 8968275 ~ 9087566 (-)
XLOC_005181 cyp26a1 coding downstream 138610 8954761 ~ 8958353 (-)
XLOC_005180 CR354554.1 coding downstream 236656 8860193 ~ 8860307 (-)
XLOC_005179 jmjd1cb coding downstream 278964 8581875 ~ 8817999 (-)
XLOC_005178 NA coding downstream 521938 8573933 ~ 8575025 (-)
XLOC_005185 NA coding upstream 94704 9227386 ~ 9237794 (-)
XLOC_005186 pth3r coding upstream 124775 9257457 ~ 9294819 (-)
XLOC_005187 CR457459.1 coding upstream 212682 9345364 ~ 9345485 (-)
XLOC_005188 erbb2 coding upstream 227634 9360316 ~ 9438227 (-)
XLOC_005189 pgap3 coding upstream 316983 9449665 ~ 9468618 (-)
XLOC_005175 NA non-coding downstream 616255 8477459 ~ 8480708 (-)
XLOC_005174 CR354434.1 non-coding downstream 652942 8443904 ~ 8444021 (-)
XLOC_005173 NA non-coding downstream 702318 8388330 ~ 8394645 (-)
XLOC_005195 AL732629.1 non-coding upstream 515546 9648228 ~ 9648345 (-)
XLOC_005196 AL732629.2 non-coding upstream 537245 9669927 ~ 9671137 (-)
XLOC_005199 BX928755.1 non-coding upstream 927954 10060636 ~ 10063668 (-)

Expression


Co-expression Network