AMCG00020895 (gck,gk,LOC106580581,LOC106585167)


Basic Information

Item Value
gene id AMCG00020895
gene name gck,gk,LOC106580581,LOC106585167
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030127.1
NCBI id CM030127.1
chromosome length 42978078
location 36021637 ~ 36029074 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00020895
ccacacacacaggcacgcacacacacagatacgcACTCTTACACCGCCGCGGACACTCTGACGAACTTCCACAAGATGCCGTGCGCTACTTGCCGTTCTAACCACGCGGAGAAGTTGAGAGTGTTCCACAGACGTGGCTCCATTTTTGAAAGAGTCCTCAGGGTAGATCAGATCCTGTCCGAGTTTCGGCTGAAAAAAGAGGAGCTGAAGGAGGTGATGAAGCGGATGCAGCACGAAATGGACCGCGGCCTGCGTCTGGAGACCCACGATGAAGCCAGTGTCAAGATGCTGCCCACTTATGTGCGCTCTACTCCTGAAGGATCAGAGGTGGGGGACTTCCTGGCCCTGGATCTTGGGGGGACAAATTTCCGAGTGATGCTGGTGAAGGTGGGGGAGGATGAGGAGAGGGGCTGGAAAGTGGAGACCAAACATcaaatgtactccatcccaGAGGACGCCATGACGGGTACAGCGGAGATGCTGTTCGACTACATTGCCGAGTGCATCTCCGACTTCCTGGACAAGCACAACATGAAGCACAAGAAGTTGCCACTCGGCTTCACCTTCTCCTTCCCGGTGCGGCACGAGGACATCGACAAGGGCATCCTGTTGAACTGGACCAAGGGCTTCAAAGCCTCTGGAGCTGAAGGCAACAACGTGGTGGGTCTTCTCCGGGACGCCATTAAAAGGAGAGGGGACTTTGAAATGGACGTGGTTGCTATGGTGAACGACACAGTAGCCACCATGATCTCCTGCTACTACGAAGACCGCAGCTGCGAGGTCGGGATGATTGTAGGGACGGGCTGCAACGCCTGCTACATGGAAGAGATGCgcacagtggagctggtggAGGGCGAGGAGGGGCGGATGTGCGTGAACACCGAGTGGGGAGCCTTTGGGGACAATGGCGAGCTGGAGGAGTTCCGGCTGGAGTACGACCGCGTGGTGGACGAGACCTCTCTCAACCCCGGCCAGCAGCTctATGAGAAGATCATCAGTGGGAAATATATGGGTGAGCTGGTGCGGCTGCTCGTGCTGAAGCTGGTCAATGAGAACCTGCTGTTCAACGGTGAGGCCTCTGACATGTTGAAGACCAGGGGCAGCTTTGAAACTCGCTTCGTGTCCCAGATCGAGAGCGACTCTGGAGACCGCAAGCAGATCTACAACATCCTGACAACACTGGGTGTGCTGCCGTCCGAGCTGGACTGTGACATCGTGCGACTGGCCTGCGAGAGTGTGTCCACGCGTGCCGCCCACATGTGCGGGGCTGGGCTGGCTGGCGTCATCAACCGGATGAGAGAGCGACGCAGCGAAGAGGCCCTTAAGATCACCGTCGGAGTGGATGGCTCGGTCTACAAACTGCACCCCtgCTTCCAAGAGAAATTTCATAAAGCGGTTCGGGATTTGACCCCTCGCTGCGACATCACCTTCATCCAATCAGAGGAAGGAAGTGGACGGGGGGCGGCCCTCATCTCCGCCGTGGCCTGCAAAATGGCGTGCATGCTGAGCCAGTGAGGGATGTCCTTGCTGCCTCCTAGCACTAGGGGGAGCCTGTCTCCCCAACAATGGACTGTAGCCTACTGGACCGCTTCTCCGCCCTCTCATTTGTAGCCAGAATGGGCATCAATTGCCAGGGGAATGCTCTCTCCTAAACTGCAATTTTTGCATGTCATGGAGGGCACCCTGCAgcacactgaaaacagcacaggGGATTCTGGGATTCAGAGCTGTTTTgcaccaaaaatacaaaacactggtCAAAACTTGTAAAAACAGCCTCGTCTCCTACTTTGCGAGTCAGTATCCCCAGATAGGTCTTTAGTTCATAGCAGAGCTCCTTGTTCTGTGTTTAAGTAAAAGTTTTTTGCAGACTGGCTTGAAACTGAGGTAGCAGATAGGGCCTACTCTGTGTATGTGCAGGCCACAGCCacagaaactaaactaaaattatGATCTCTAATCTCTCTGCAGCTTCTTCGGCACACAAAGCCAAAgcagtctgtttttttccccagaattGCTGAAATTAAgtgttactattatttattCCATATTTTCAATCAGGATTTAGCCAGTTGTCTGATGTGTGATGTTGTAGGCCAAGTCCAGATTGTACAGTTCTGACTCCTGTATTGTAGTGATGTAATAATATCCTTGTATTAATGTTGTGGTCTTTTCTCAaatggaaaagggaaaaataagcTCTGAACTCTATGTGGGCTATTTCTGGACTGAATCTCATATCCTGTGAAAAATGGTACATAATCTGTAAGCAGGAATGGTGTAAATGTAGGCCAGAAacctttgtaaataatgttgtTAACCTGTAATCtgctgtagtgtgtgtgagaaaaaaactgtaaagcTGGATAAACCTTTGATTTCATATGCTTTTATAAGTGCCTATATCCTCTACTATTGCATCACTTATTAATGTTGAAAGGCCAattttatatgcatatgtatgagTGTGTCTTACACCAGATATGAAACTGCCTTAATTACATGACATGAAAACAGGAAAgctatatacataaacacatttagtGATTAGTGCACTTCCTGATGTAACCAAATAAAATACCCACTACAGTATACAGTGCTTGTGTTCACTCCATGCAGCCTGTACTAATAAAAGGCATTTGACCTGGTGACGCGCTTTGACATGTTTCAGACTGTGCCGCATGGGCAGCAGGAGACAGAAAAGGCCCAATTAGGAGTCAGTTGCTCTGACAGGCTCTGACTGCACAGCCCTGTCTTATCAGGGACACGTATTGGCAGAAGATAGCCAGCTCAAATCTGTTCCATGTAAAGTAATGATCTGTAAACAATAAacttgtatgtttaaaaaaataaa

Function

symbol description
gck Predicted to enable fructokinase activity; glucokinase activity; and mannokinase activity. Acts upstream of or within glucose homeostasis; pancreas regeneration; and type B pancreatic cell development. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including digestive system; female organism; heart; male organism; and muscle. Human ortholog(s) of this gene implicated in artery disease (multiple); familial hyperinsulinemic hypoglycemia 3; and glucose metabolism disease (multiple). Orthologous to human GCK (glucokinase).
gk Enables glycerol kinase activity. Involved in glycerol metabolic process; glycerol-3-phosphate biosynthetic process; and triglyceride metabolic process. Located in extracellular exosome. Implicated in glycerol kinase deficiency.

NR:

description
PREDICTED: glucokinase

GO:

id name namespace
GO:0032024 positive regulation of insulin secretion biological_process
GO:0045721 negative regulation of gluconeogenesis biological_process
GO:0045725 positive regulation of glycogen biosynthetic process biological_process
GO:0046835 carbohydrate phosphorylation biological_process
GO:0051156 glucose 6-phosphate metabolic process biological_process
GO:0006096 glycolytic process biological_process
GO:0042593 glucose homeostasis biological_process
GO:0051594 detection of glucose biological_process
GO:0005524 ATP binding molecular_function
GO:0005536 glucose binding molecular_function
GO:0004340 glucokinase activity molecular_function

KEGG:

id description
K12407 GCK; glucokinase

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00020895 True 2857 mRNA 0.50 10 36021637 36029074

Neighbor

gene id symbol gene type direction distance location
AMCG00020890 NA coding upstream 34945 35958629 ~ 35986692 (+)
AMCG00020892 ddx56,LOC107751685 coding upstream 71462 35937442 ~ 35950175 (+)
AMCG00020893 tmed4,LOC107093818,LOC106566412,LOC101466713,LOC102209141 coding upstream 84487 35930622 ~ 35937150 (+)
AMCG00020891 NA coding upstream 95143 35909352 ~ 35926494 (+)
AMCG00020884 NA coding upstream 161942 35851639 ~ 35859695 (+)
AMCG00020896 myl7,LOC107753162,LOC107703146,LOC107657323 coding downstream 1259 36030333 ~ 36033302 (+)
AMCG00020894 NA coding downstream 5797 36034871 ~ 36043978 (+)
AMCG00020902 ash2l coding downstream 72523 36101597 ~ 36114326 (+)
AMCG00020901 bag4,LOC107702866,LOC107571962,LOC103396927 coding downstream 149851 36178925 ~ 36184018 (+)
AMCG00020907 dusp26,LOC102218034,LOC106904628 coding downstream 158675 36187749 ~ 36194843 (+)
G66342 NA non-coding upstream 164609 35798710 ~ 35857028 (+)
G66348 tmem127,LOC106585551,LOC107713035,LOC107699648 non-coding upstream 203858 35813743 ~ 35817779 (+)
G66325 NA non-coding upstream 253066 35768241 ~ 35768571 (+)
G66319 NA non-coding upstream 260605 35758108 ~ 35761032 (+)
G66290 NA non-coding upstream 305388 35716045 ~ 35716249 (+)
G66524 NA non-coding downstream 695820 36724894 ~ 36725129 (+)
G66528 NA non-coding downstream 777246 36806320 ~ 36806577 (+)
G66602 NA non-coding downstream 1044605 37073679 ~ 37074634 (+)
G66696 NA non-coding downstream 1259440 37288514 ~ 37288841 (+)
G66700 NA non-coding downstream 1272174 37301248 ~ 37301598 (+)
G66362 NA other upstream 113235 35867393 ~ 35908402 (+)
AMCG00020874 NA other upstream 271191 35747156 ~ 35750446 (+)
G66149 NA other upstream 856652 35163813 ~ 35164985 (+)
AMCG00020855 NA other upstream 872219 35147603 ~ 35149418 (+)
G66060 NA other upstream 1013315 34967844 ~ 35008322 (+)
G66506 NA other downstream 225625 36254699 ~ 36256511 (+)
G66551 NA other downstream 885741 36914815 ~ 36917436 (+)
AMCG00020942 NA other downstream 1537962 37567036 ~ 37575856 (+)
AMCG00020954 NA other downstream 2087988 38117062 ~ 38137073 (+)
G67108 LOC100846954 other downstream 4292039 40321113 ~ 40321821 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000053_05704944_05710574 GCK, GK coding CI01000053 null 5704848 ~ 5711121 (+)