cdk4 (cdk4,LOC107747701,LOC106565448,LOC107701179,LOC107567936)


Basic Information

Item Value
gene id cdk4
gene name cdk4,LOC107747701,LOC106565448,LOC107701179,LOC107567936
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035918.1
NCBI id CM008321.1
chromosome length 32506130
location 21647105 ~ 21663599 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007248384.2
ACAGGACCGGAAGCATCTCATTTTCACAATGAGTTCAAAGTGAGAAGGGGAGAAAAGTTCGAGAAAGCTGAAAAAGCGTAAAAATATTTGCGTTTTAATCGTTAACGCTAAAAATACCGAAGCGCGCACGCTTAACCGGGTTGGATGGAGCGCGCGGGGCGCGAGGACGCGCAGATGTGATGATTTGGGGTGGTTATTGGGTAATATTGGGGTGATTTGTGGTCAGTCTGGCTGGAGACAGCGTGCTAGTTTGCTTCGCAAACAATACGATGGCTATGACCCAGGAGGGCGGGGTCCAGTATGAACCGGTGGCGGAGATCGGCGGTGGTGCATATGGGACTGTGTATAAGGCTCGGGATACACAGAGTGGTCAGTTTGTGGCCCTGAAGAGTGTCCGTGTTCAGACTGACCAGGAGGGCCTCCCGCTGTCAACAGTTCGAGAAGTGGCCCTGCTGAAGAGACTGGAGCAGTTCGACCATCCAAATATTGTCAAGCTGATGGACGTGTGCGCCACACTGAGAACAGATCAGGAGACAAAAGTTACGCTGGTGTTTGAACACGTGGATCAGGACTTAAAGACGTATCTGGAGAAAGCTCCAGCTCCAGGACTTCCTGTTAGCCGAATTAAGGATTTGATGCAGCAGCTGCTTTGTGGGCTCTCCTTCCTGCACTCTAATCGGGTTCTCCATCGGGACCTGAAGCCTGAGAACATCCTGGTCACTAGCAGGGGGCAGGTCAAACTCGCAGACTTCGGCCTGGCTCGCATTTACAGCTGCCACATGGCACTCACCCCAGTGGTAGTGACGTTATGGTACCGATCTCCAGAGGTCCTGCTCCAGTCCACCTACGCCACACCTGTAGACATCTGGAGCACAGGCTGCATCTTCGCAGAGATGTTCAGACGCAAgcctTTGTTCTGTGGAGAATCAGAAGTGGACCAGCTAACAAAGATTTTTTCTGTTATCGGCTTGCCAAGTGAGGAGGAGTGGCCTACTGACGTCACGCTCTCCCGACGGAACTTCAGCCCCCAAAGcccccagccaatcacagactATGTTCCTGAGCTCCGTGAAGATGGAGCAGACCTTTTATTGaaaatGCTGACTTTTGACCCGTTGAGAAGGATCTCTGCACTGAAGGCTCAGGAGCACCGGTTCTTCTCTGAACACACTGGTAACTCTTAGGACACCCCGACTGAGATCAGTGCGGTTCTGCAGTGGAAATGTTCGTGATGTAATTACCGGTTGCGTCAGTGGGCGGTTTGCTTGCCGGCTGAGTGGGTTCAGTAATCAGATGGAAACCTGGGATGCCAGCAGGTCACGCATCCATTGGACGGCCGACTCTTAAACCTGAATGTTCTGTGTTTGAAACCCTGCTGCGGCGTAATGTTTGTACATGAAGGGTAGACCTTAATtgtttcctctttcttttttttttattttattaataacttaaatatGATCAATCCAGTCCTTTTATTAACATTTGTCTACCAACCGAATCAGCGcacacactgtgctgtccaAAAGTATGTAGACACCCAGCATTTCTGCTGAAATTAAGAAtgttttccagatttttttttttgccttttactGCAGTAGCAACCTTTACCCTTTTAGGATGCAAGAAACACTTGCTGTTGGAACATTTGATTTCATTCAGCCCAACAAACTCAATCTGTGTGTGCCAGCCAACTTATTTTAGAAGCCTGTCCGTATACTTTTGGACACGTAGCGTATGAATATAGTAGCATTCTGGACAGTATGGATGAGTGGATGAATGTAAACGCTAAGCCTCATTAAGATAATCATTTACAGCTCTGCCCATCGGCAGGATACAACTGATTAATAGGCTTTTATCGTTTTTCAAAATTAAAGTCCTCAGTGGTACAACCTGAGCACTCTGTACTGCACGTTTCCTCAGTATCagacattttatttgatttgattttaagcAGCAaccagtttaattttatttttaattttattttgtttaagagCATAGACACCATTCAGTGATTTATAAGTTAATAACGCATTTTACGTAAGTTTAACCGTTAATATATATTCTGGTGGAATTTCCAAGACAGGATTACCTGACTGacaatctttttacattgacttccagtGATTTAGATAATAAGGTCCTGTTTGTCGCTGTTTggagatacaagtttttttttttttttatgtaaataaaccaACCATTACTGAACAACCATTTCAACAACTGTATAAAAAATTTCCAAGCATAAAGGCAAGCTAGTCCAGAGAGGCGTAACGCATAAATCCGTTAAAGCAGAATTCACTGCcgataaataatataatatgtcaaagtgcacaaaatcattcctgtttttattatgtattttatatgacCTTATTTTTATACACC

Function

symbol description
cdk4 Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and regulation of cell cycle. Predicted to act upstream of or within phosphorylation. Predicted to be part of mediator complex. Predicted to be active in nucleus. Is expressed in oocyte stage I and ovary. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); familial melanoma; glioblastoma; obesity; and type 2 diabetes mellitus. Orthologous to human CDK4 (cyclin dependent kinase 4).

NR:

description
PREDICTED: cyclin-dependent kinase 4-like isoform X1

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process
GO:0005524 ATP binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
K02089 CDK4; cyclin-dependent kinase 4

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007248384.2 True 2397 mRNA 0.44 8 21647105 21663599

Neighbor

gene id symbol gene type direction distance location
LOC103033505 agap2 coding downstream 16771 21598127 ~ 21630334 (-)
LOC111195407 NA coding downstream 64042 21572367 ~ 21583063 (-)
arfgap1 arfgap1 coding downstream 76454 21550755 ~ 21570651 (-)
LOC111195406 NA coding downstream 138844 21508052 ~ 21508261 (-)
itga7 itga7 coding downstream 149042 21442288 ~ 21498063 (-)
LOC103023479 tnnc1,LOC103023479,LOC108424583,LOC106571909,LOC103385538 coding upstream 341835 22005434 ~ 22012959 (-)
tmbim6 tmbim6,LOC106583271 coding upstream 527225 22190824 ~ 22205696 (-)
avil avil coding upstream 543523 22207122 ~ 22229088 (-)
ctdsp2 ctdsp2,LOC106583267,LOC106565429 coding upstream 573848 22237447 ~ 22247617 (-)
LOC103037062 LOC108424641,LOC106583265,LOC103359365,LOC100304514 coding upstream 596060 22259659 ~ 22284657 (-)
G191812 NA non-coding downstream 119069 21526159 ~ 21528036 (-)
G191791 NA non-coding downstream 276326 21303518 ~ 21370779 (-)
G191787 NA non-coding downstream 367353 21279003 ~ 21279752 (-)
G191691 NA non-coding downstream 407583 21173472 ~ 21239522 (-)
G191664 NA non-coding downstream 540283 21105440 ~ 21106822 (-)
G191827 NA non-coding upstream 46317 21709916 ~ 21711285 (-)
G191858 NA non-coding upstream 169543 21833142 ~ 21833495 (-)
G191870 NA non-coding upstream 196527 21860126 ~ 21924848 (-)
G191880 NA non-coding upstream 294242 21957841 ~ 21958432 (-)
G191884 NA non-coding upstream 302910 21966509 ~ 21966712 (-)
elmo2 elmo2,LOC106583331 other downstream 102274 21510924 ~ 21544831 (-)
npff npffl,npff,LOC107738884,LOC107677943,LOC107669931 other downstream 210652 21430016 ~ 21436453 (-)
brk1 brk1,BRK1,LOC106565571 other downstream 543887 21099347 ~ 21103218 (-)
LOC103036492 card19,LOC108443695 other downstream 2118525 19511321 ~ 19528580 (-)
LOC103032794 tusc2,tusc2b,LOC107593101,LOC107587002,LOC107695626 other downstream 2744820 18897509 ~ 18902285 (-)
G191862 dusp7,LOC107561798,LOC107697567,LOC107677944 other upstream 183370 21846969 ~ 21851642 (-)
alas1 alas1,LOC106583798 other upstream 685748 22349347 ~ 22362458 (-)
amhr2 NA other upstream 1045950 22709549 ~ 22722905 (-)
LOC103041653 phf20,LOC107655063,LOC107727854,LOC107561906 other upstream 1122564 22786163 ~ 22803642 (-)
G192251 adipor1,LOC107749488,LOC107385668 other upstream 1391034 23054633 ~ 23058805 (-)

Expression


Co-expression Network