wnt4 (wnt4,wnt4a,LOC107565731,LOC107654388)


Basic Information

Item Value
gene id wnt4
gene name wnt4,wnt4a,LOC107565731,LOC107654388
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035918.1
NCBI id CM008321.1
chromosome length 32506130
location 5725343 ~ 5731344 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022682302.1
GCGCAACGTGGAGGTGATGGACGCGGTCCGTAGAGGAGCACAGTTAGCCATCGACGAGTGCCAGTACCAGTTTCGCAACCGACGCTGGAACTGTTCCACACTGGAGACCGTCCCTGTCTTTGGGAAGGTGGTCACCCAAGGCACCAGGGAGGCCGCCTTCGTGTATGCGATCTCTGCTGCAAGCGTGGCCTTCGCCGTGACCAGGGCCTGTAGCAGTGGGGAGCTGGAGAAGTGTGGCTGCGACCGCAACGTGCACGGCGTAAGCCCAGATGgcTTCCAGTGGTCAGGGTGCTCTGATAACATCGCCTATGGAGTCGCCTTCTCCCAGTCGTTCGTGGACATCAGGGAGCGAGGCAAAGGGCAGTCGTCCAACAGAGCACTTATGAATCTCCATAATAATGAGGCGGGGAGGAAGGCCATTCTGAACCACATGCGAGTGGAGTGTAAATGCCACGGTGTCTCAGGCTCCTGCGAGGTGAAGACCTGCTGGAAGGCGATGCCGCCGTTCCGCAAAGTGGGCAACGTCATCAAGGAGAAATTTGACGGCGCCACGGAAGTGGAACAGCGCAAAATCGGCACCACCAAAGTGCTGGTGCCGCGGAACTCGCAGTTCAAGCCGCACACGGACGAGGACCTGGTCTACCTGGACCCCAGCCCGGACTTCTGCGACCACGACCCCCGGACGCCGGGCATGCTGGGAACGGTGGGCCGCTACTGCAACAAAACCTCCAAGGCCATCGACGGCTGCGAGCTGATGTGCTGCGGCCGCGGCTTCCACacggaggaggtggaggtggtggacAGGTGCAGCTGCAAATTTCACTGGTGCTGCTACGTCAAGTGCAAACAGTGCCGCAAGATGGTGGAAATGCACACGTGCCGGTGATCCACTTACGCGCTCCTTCAGCTCCCCTCTGCTGAACTTTATTTAGAACGACTGACTCCCTTTTCCCTGCCACTTCCTTGAACCTTAAGACCACCCTGGGAAACCAGACGAAtatgagaagaagaagaagaagaagaagaagaagaagaagaagaagaagaagaagaagaagaagaagaagaaaataaaaaaaacacacacacagagggaacAGAGACATTCCCCCAATCATACATTCATAcattaaagaattaaagaacATGTCATACATGGGACGTACATATCTAGGGGCAAATagagttgtttttattatttttttgttggtatttttatttcaagTCCCACTTGAGAGTAtttttctctccattttttttcttttgtttttaaatgtgattgctctcttatttttgtatttttttttttaacttattggAATCAGAGAGTGAATTTTTAATGTGACTTGCTCCAAGGGGAGTGGTACGGGGTCCAGGAGGGTTGATGGACTAGGATTAGAACAGCGGGGTTCTGAAGGAGACGAGTTGGAGTTGGAGTTGGAGATGAAATTGGAATTGGCCGGGGGTAAAGTTTCACCCCCTCCAATCATTGATGCTGCTTTAGGATCTCACCTGGAGTGACGGACATCAAGGGATTTTTTTCTAACGGACTTCCAGAACGAGGAACATTACATCTTACATCTTGAGATGCAGTCCAGGTGTacattttacgttttttttttctctcggaAAGAAAAGTAGCATTTTAGATTTGTATTTGGCCATTTGTATGTGGCTGAAGGATGCTgcttcagaaaaacaaaaactcaccaATAATGTGTACAGCAGTGATGAtatcattataatattattattgaggGAAGCAAACCAACTCAAAAAAAACGAGACTGAACAAACCAACTACAAGCATACCGTTGAAAcacttacagaaaaaaaagaacagtgtattaaattaatttcaaaATCCTAGAAGGTACACACCATTGGCTTTTGGAATGGTTACCATCTTTCTTCCCAaaaataacatcagaaaaaaaaaacaagtttttccATGGACCATGGATACTGTGCACGGTGACTCCAGCACTTTTCATCTCCAGATGCACataccacaaataaataaaaaaaaaaaaattcccaaaGCATTCCCTGTTCTATCGACGTTGAGGCAGAGTGACTTATTGAGTTATTTATGACAACTATGTACAACTACCATAATTCCAAGTGTTCTATAGTACAACCATGCTATCCAATATGCTTCTAAAGAAACATAGCTCTGTAAAAGACTTATACACTGAAGAGGACTATAATGCATATGATGAATGTATGTCTAATTGAAATATATGCCATGTGAAAGACTGA

Function

symbol description
wnt4 Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within several processes, including animal organ development; regulation of axon extension involved in axon guidance; and sensory epithelium regeneration. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including central nervous system; head; neural rod; neural tube; and reproductive system. Human ortholog(s) of this gene implicated in Mullerian aplasia and hyperandrogenism. Orthologous to human WNT4 (Wnt family member 4).

NR:

description
PREDICTED: protein Wnt-4

GO:

id name namespace
GO:0060070 canonical Wnt signaling pathway biological_process
GO:0042074 cell migration involved in gastrulation biological_process
GO:0007507 heart development biological_process
GO:0045165 cell fate commitment biological_process
GO:0048841 regulation of axon extension involved in axon guidance biological_process
GO:0045893 positive regulation of transcription, DNA-templated biological_process
GO:0070654 sensory epithelium regeneration biological_process
GO:0021986 habenula development biological_process
GO:0005615 extracellular space cellular_component
GO:0005109 frizzled binding molecular_function

KEGG:

id description
K00408 WNT4; wingless-type MMTV integration site family, member 4

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022682302.1 True 2262 mRNA 0.46 4 5725343 5731344

Neighbor

gene id symbol gene type direction distance location
fbxo2 NA coding upstream 207778 5508308 ~ 5517565 (+)
LOC103021734 dnajc11,LOC107654442,LOC107751176,LOC103038967 coding upstream 238930 5472482 ~ 5486413 (+)
LOC103023081 LOC108441425 coding upstream 785278 4936994 ~ 4940065 (+)
tnfrsf9 NA coding upstream 830302 4887519 ~ 4895041 (+)
LOC103023712 NA coding upstream 840977 4873029 ~ 4884366 (+)
ap5b1 ap5b1 coding downstream 34105 5765449 ~ 5771297 (+)
cldn19 cldn19,LOC107654447,LOC107582397,LOC107751184,LOC107565733 coding downstream 86640 5817984 ~ 5835626 (+)
LOC111195362 NA coding downstream 415341 6146685 ~ 6147519 (+)
LOC103043936 nucks1,nucks1a,LOC108255091,LOC107654381 coding downstream 510683 6242027 ~ 6258457 (+)
LOC103043630 LOC108437608 coding downstream 545455 6276799 ~ 6288068 (+)
G187484 NA non-coding upstream 84287 5640822 ~ 5641056 (+)
G187477 NA non-coding upstream 223467 5499104 ~ 5501876 (+)
G187475 NA non-coding upstream 229929 5494470 ~ 5495414 (+)
G187471 NA non-coding upstream 234086 5490085 ~ 5491257 (+)
G187472 NA non-coding upstream 235513 5488960 ~ 5489830 (+)
G187493 NA non-coding downstream 28173 5759517 ~ 5843830 (+)
G187583 NA non-coding downstream 154458 5885802 ~ 5886002 (+)
G187584 NA non-coding downstream 157489 5888833 ~ 5899725 (+)
G187610 NA non-coding downstream 373848 6105192 ~ 6178630 (+)
G187640 NA non-coding downstream 569508 6300852 ~ 6302749 (+)
G186978 rps23,rs23,LOC106566095,LOC106566598 other upstream 2330500 3392387 ~ 3394843 (+)
G186880 lmcd1 other upstream 2723328 2980497 ~ 3002015 (+)
podxl2 NA other upstream 4630006 606833 ~ 1095337 (+)
cers5 cers5,LOC107698577,LOC107590873,LOC107694004,LOC107718462 other upstream 5187127 510575 ~ 538216 (+)
G186231 NA other upstream 5610256 107396 ~ 115087 (+)
p3h1 NA other downstream 48547 5779891 ~ 5798979 (+)
LOC103029365 NA other downstream 1345821 7077165 ~ 7098672 (+)
trnaq-uug_4 NA other downstream 1460810 7192154 ~ 7192226 (+)
LOC111195452 NA other downstream 2380659 8112003 ~ 8113242 (+)
agtrap agtrap other downstream 2525452 8256796 ~ 8271712 (+)

Expression


Co-expression Network