XLOC_007678 (npm1b)


Basic Information

Item Value
gene id XLOC_007678
gene name npm1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007125.7
NCBI id CM002898.2
chromosome length 52660232
location 5588029 ~ 5642461 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00015055
AAAGCCCGCCCACTTCTACACTCTCATTCGTCCATTTCGATGTCAATCAACACGCCGGAACTACGTTTAACAGGACCTGTGCGCGCAAAAATGGAGGATAACATTAAAGACCTCAGCCGACCCCAGATGTATTTGTTTGGTTGTTCGTTAAAGGCTGACAAGAAAGAGCACAAAGTTGACCTGGATGATGATGAGGCTGAACATCAGCTGTCACTTAAGTCGGTGTGTTTGGGTGCCGAGGCGGAGGATAAATTCCACACCGTGGAGATGGAGGGATTGACTTACGATGGCAAAACCACCAAAATCACACTTGCTGTATTGAAACCATCCGTTCTGCCTTCTTTAAGTCTGGGCGGTTTTGAGGTCACTCCTCCTGTGTCCTTTCGTCTGCAGTCCGGAGGGGGGCCGGTCTACATCAGCGGTCAACATTTTGTCAGTGTCAAGGAGTCAGATGATGAggatgaggaggaagaggagaacaACACTTCACCGGTGAAGAGACCGTCCAACATGACCCTCGCCAAAGTGCCTCAGaaaaagctGAAAATGGACTCAGATGAGGATGAAGACAgcgatgatgatgacgacgacgacgacgatgatgatgatgatgaagaagaGGATGATGACAAACAAGAAAAGCCTGCTGTAAAGAGCCCTGTCAAATCCACTCAAAAAacTCCAGAGAAGAAGAAAAGTGCGGATAAGCAGAATGGCTCTCCAGACAAGAAAGCAGGGACATCAGGGAAGCCCCAAACTCAGACACCGCAGAAAGTAAAAGACAAGTCTGCTGCAGGGCCTTCTGGGAAGACTCCCAGCATTCCCAGCCTGAGTGAAGTCAAAAGCAAACTTACATCAGCAGCTAAAGAGGGGAAGCCATTTCCAAAGACGGAACAGAAGTTCGAGAACTTCGCTAGAAGCTCTTTCAAGATCTCTGATAAGCAAGTGATCAAAGACCTTTGGAACTTTGTACAATCACTAAAAAAGTAATGGCTGCTCTGCGCTCCCCGTCCAGTCCCAGTGCAGCAGAAGTCTGCGGTTCGCCAGTAAACGGCACTTCAGCTGTACGATTCTGGCCTCTTCCCGTGTTAATGCGATCCGCCTGCTCTGCTCTTCTCTGTCGAGCAGAAGAGTCCTCGGCAGGGGTTACAGATATCATGCATCATCTTTtatattctttattttgtttttaaatgatggattttttttttttttttaggtcctCAATGGTTTCTTATAGTGGTATGCTTTTTAAAGGTGTCTCTTGGTAACTCACAAAATTGTTATCAAACATTTCCAGatcttatttaattaaaattggtTAAGAGggtggaaaataaaaataaagtgtttagtttGAAGTAAATTAATCCTATTTTAAACTTATGCCTAGTGCATAATAACATTTTCCCCATTTCTCATTATCATAAAGCAAAAAAAGTGAATGAAATATTGTCAGATTTATAGACCAtagaatcatttttttttacacactgagttatttgaatatatttttttaattatataaaggaGTCAGTGTAAAATTAGTGGGGAAATGTTTATGTAAAATAGGTAAATGGTCATAAAAATAATCTTTGtttttctaatataatatatatatatatgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtataataaaacagctaagaaaaatatatatatttttgtgtgtttgtgttttttatttatttatgaataaataaacactctaaaacactaaatatatatatttatttaaaaattataataaaaaacaggctaaaaacacacacacacacaatatatatagcgtttatatatataaacgctaaaatatataaatatattttcttgtgtgtttttaccatgttttttattataattttaaaaaaattaaaaacaccaaaaatgtgtattttttgcaatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatattatatatatatatatatatatatacatatatatacatataattttaatattaaaataataataatataataaatatattaaataatattatatattaaataataataattaatttagtattaaaaaattatatatatatatatatattttttttatattattattcatataaaaattataataaaaacactacaaatttgttttaattaattaatataaattctaATTAAAAGAAAACacgctaaaacacacacacacacacacacacaaatatgtttatatgttgtaatttatgttatatattataacatataaatattataatatatttttttatataatttttttacaaaaagtaatttttaaaaaacacacaatcaCTATACATATATTTACAGACAACAAGGGGTATTTTTATGAccattatattatttttgagaccaattgttttttttttttttttttttttgaaaaaatctgATCTTGGTTATGAGTTTGTGAGTGCCACTcttaaatataaaactgatattgGCTGCTGCTGGTTTatctcagtttttgtttttttactatcattttttttttaaagctacaaAACTCCTGTTAGCTATCTTAAACAAAACACCCCTTTTTTGCACTAGCAGCCCAAGACCAATTTGTTTCTGGCGTATATTTAAAACCATAATCACTGTAAACCGTCCTCCTTAATTTCTTTGTGTTAAGATGGCAGCTGAAGTGTAATAATGTCAAAGATTATTTCAGAAGATTCCGTCTGGTTCTTAGTATTGAGTGCAGCCCTCAGGATCATGCAGATGCAGACGGCCTTGAACATGTCAGATGTACTATTAACTCAAGTGCTACAGACTCTCCCATTTAAATCACGTCGAGAAGTGCGGTCAGAATGTTATTCCTTGTTGGAAAAAAGGAGGAAAGTTAGTCAAGTGTTCAGCTCATTAAACATGACAGCAAGGATGTTTAGTTGATTTGGTGCTTTGAAATCAAACGTTTGGTAAATTGTTCTTTTGTtgtattggttttatttttgcactaaatcattttaattgtttttttttttttttaattaatcagaaTAATCTGTCCttgttttaattagtttgatGAATACTAGTGAAACTGgtacaaatgtatttgtttagtttttttacaccATGTATATGTTGCAAGCAAGCAGTGTGTCTGTTGGAAAACTACATTGTTTGTTGGTTTACACTGAGATCAGTCTAGTGTTGTAGCATCATGCTGTTTGGTTGCAGTGTTAGATTGGGTTTCATGCCTTGGAATGAAAAAGAGTTAATCCATCCTTAGTTAGTACATTGAATAAATACTGAATAACAAA
>TCONS_00015056
ATGGAGGATAACATTAAAGACCTCAGCCGACCCCAGATGTATTTGTTTGGTTGTTCGTTAAAGGCTGACAAGAAAGAGCACAAAGTTGACCTGGATGATGATGAGGCTGAACATCAGCTGTCACTTAAGTCGGTGTGTTTGGGTGCCGAGGCGGAGGATAAATTCCACACCGTGGAGATGGAGGGATTGACTTACGATGGCAAAACCACCAAAATCACACTTGCTGTATTGAAACCATCCGTTCTGCCTTCTTTAAGTCTGGGCGGTTTTGAGGTCACTCCTCCTGTGTCCTTTCGTCTGCAGTCCGGAGGGGGGCCGGTCTACATCAGCGGTCAACATTTTGTCAGTGTCAAGGAGTCAGATGATGAggatgaggaggaagaggagaacaACACTTCACCGGTGAAGAGACCGTCCAACATGACCCTCGCCAAAGTGCCTCAGaaaaagctGAAAATGGACTCAGATGAGGATGAAGACAgcgatgatgatgacgacgacgacgacgatgatgatgatgatgaagaaGATGATGACAAACAAGAAAAGCCTGCTGTAAAGAGCCCTGTCAAATCCACTCAAAAAacTCCAGAGAAGAAGAAAAGTGCGGATAAGCAGAATGGCTCTCCAGACAAGAAAGCAGGGACATCAGGGAAGCCCCAAACTCAGACACCGCAGAAAGTAAAAGACAAGTCTGCTGCAGGGCCTTCTGGGAAGACTCCCAGCATTCCCAGCCTGAGTGAAGTCAAAAGCAAACTTACATCAGCAGCTAAAGAGGGGAAGCCATTTCCAAAGACGGAACAGAAGTTCGAGAACTTCGCTAGAAGCTCTTTCAAGATCTCTGATAAGCAAGTGATCAAAGACCTTTGGAACTTTGTACAATCACTAAAAAAGTAA

Function

symbol description
npm1b Predicted to enable RNA binding activity; chromatin binding activity; and histone binding activity. Acts upstream of or within hemopoiesis and regulation of apoptotic process. Predicted to be located in nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in centrosome; cytoplasm; and nuclear lumen. Is expressed in several structures, including eye; fin bud; hematopoietic cell; hematopoietic stem cell; and somite. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human NPM1 (nucleophosmin 1).

GO:

id name namespace
GO:0030097 hemopoiesis biological_process
GO:0042981 regulation of apoptotic process biological_process
GO:0006338 chromatin remodeling biological_process
GO:0000055 ribosomal large subunit export from nucleus biological_process
GO:0000056 ribosomal small subunit export from nucleus biological_process
GO:0006407 rRNA export from nucleus biological_process
GO:0042273 ribosomal large subunit biogenesis biological_process
GO:0042274 ribosomal small subunit biogenesis biological_process
GO:0010824 regulation of centrosome duplication biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:1990904 ribonucleoprotein complex cellular_component
GO:0005813 centrosome cellular_component
GO:0005654 nucleoplasm cellular_component
GO:0005730 nucleolus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0042393 histone binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0003682 chromatin binding molecular_function
GO:0003723 RNA binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-080723-7 Predicted to enable RNA binding activity; chromatin binding activity; and histone binding activity. Acts upstream of or within hemopoiesis and regulation of apoptotic process. Predicted to be located in nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in centrosome; cytoplasm; and nuclear lumen. Is expressed in several structures, including eye; fin bud; hematopoietic cell; hematopoietic stem cell; and somite. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human NPM1 (nucleophosmin 1).

Ensembl:

ensembl_id ENSDARG00000037675

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00015055 False 3431 mRNA 0.33 11 5588029 5642461
TCONS_00015056 True 897 mRNA 0.47 11 5590470 5642371

Neighbor

gene id symbol gene type direction distance location
XLOC_007677 BX276088.1 coding downstream 24838 5560755 ~ 5563191 (-)
XLOC_007676 fgf24 coding downstream 41532 5506983 ~ 5546497 (-)
XLOC_007675 pcgf1 coding downstream 180474 5394630 ~ 5407555 (-)
XLOC_007674 NA coding downstream 258853 5327056 ~ 5329176 (-)
XLOC_007673 BX510929.1 coding downstream 475238 4952114 ~ 5112791 (-)
XLOC_007679 tlx2 coding upstream 14049 5656510 ~ 5690363 (-)
XLOC_007680 kazald2 coding upstream 162467 5804928 ~ 5817039 (-)
XLOC_007681 loxl3a coding upstream 224433 5866894 ~ 5916580 (-)
XLOC_007682 FP103005.3 coding upstream 512913 6155374 ~ 6158751 (-)
XLOC_007683 FP103005.1 coding upstream 544253 6186714 ~ 6186833 (-)
XLOC_007641 CU855896.1 misc downstream 3180189 2407736 ~ 2407840 (-)
XLOC_007640 CU855896.2 misc downstream 3180598 2407328 ~ 2407431 (-)
XLOC_007639 CU855896.3 misc downstream 3180957 2406945 ~ 2407072 (-)
XLOC_007672 NA non-coding downstream 703584 4861940 ~ 4884445 (-)
XLOC_007671 NA non-coding downstream 743584 4832678 ~ 4844445 (-)
XLOC_007684 NA non-coding upstream 550788 6193249 ~ 6204004 (-)
XLOC_007687 NA non-coding upstream 687780 6330241 ~ 6402769 (-)
XLOC_007688 CT009487.1 non-coding upstream 819812 6462273 ~ 6479403 (-)

Expression


Co-expression Network