XLOC_009108 (tyw1)


Basic Information

Item Value
gene id XLOC_009108
gene name tyw1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 16739160 ~ 16872600 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00017935
ATGCAGCCGTAAAGTTAGCCCGTTATTTATATCTGAGACGTATGAAGTTAAATCTTTGTCTGGttattgtaaaacatttatttactagACTGTGTTGATGGAGAGAGTACATGAGATGCTGTTTTTATCGGTGTTGTCGGGTTTGGTGTGTTCTGCAGTCGGCGCTGAGATGTCAGGTGTTTTGAACGATGTGAGGGATTACACTGAGGGTTACCTGCAGGTTCTGTGGCAGAACAGGTTATATGTGTACTCGACTGCTGCTGTTCTCATTGGAGTCTGGTTTACTGTGAACATGCTTTTCAAAAAGaaaaaaatggtCCATCCTGTAAGTCCTCCGGCAAGTAAATCTGTGAAGAAGCAGGAACCAGCTTCTGGAGCTAAAAAAGTCATCCATGTTTCTGGGGTCAAAGTCTTTTATGGATCACAGACAGGAACAGCAAAGGGGTTTGCAAAAGAACTTGCTGAAGACGTTATTGCTCAGGGGATCCAGTGTGAGGTTATTGATATGAAAGATTTTGACCCGGAAGACAGATTGGCAGAGGAGTGCACAAGCAAGATAATCTGTGTGTTTCTGGTGGCCACATACACTGATGGACAGCCCACCGAGAGCGCTGAATGGTTCTGCAAATGGCTCCAGGAAGCATCCACTGACTTCCGATATGGGAAAACCTACCTGAAGGGAATGAGATATGCTGTTTTTGGTCTTGGAAACTCGGTTTATGTCGGCCATTACAACACAGTCAGTAAGAGCATAGATAAGTGGCTGTGGATGCTGAGCGCCGCTCGGATCATGACCAGAGGAGAAGGCGACTGTAATGTGGTGAAGAGCCGTCATGGCAGCGTGCAGGCTGACTTCCAGGCCTGGAAAGGGAAATTCTTGAACCGACTGCAGGCCCTGGCCAAGGGTGAGAAGAAAGCCTGCTCTGGAAACTGCAAGAAGGCCAGCTGCAAGAATAAGAAGAAACATAAGGAGGAGGCAGAGGACAATCACTCGCTCGCTGAGAAGAACAACTCTGAGGAGGAGCTGATGGAGTCCAGCAGCGATGAGGAGTCCTCTTCTGAAGATGAAAAGTCTCATGGCTCTGTCATCGACATGGAGGACCTCGGAAATGTTATGAATCACATGAAGAAAGCCAagCAGAGGATGGAGGAAGATGAAGAGGACTCCCAAAGAGTGAAGCAGAATGGGGAGAGGAAGAGCGAGTGTGAGGAGGAGCGCAGAGAGATGATCACTCCGGCCTTGAGAGACTCATTGACTAAACAAGGGTACAAACTAATAGGGAGCCACTCTGGGGTGAAGCTGTGTCGTTGGACTAAGTCGATGCTGAGAGGGAGAGGAGGCTGCTATAAACACACCTTCTATGGGATTGAATCGCACCGCTGTATGGAGACCACGCCGAGTCTGGCCTGCGCTAACAAATGTGTTTTCTGCTGGAGACACCACACCAACCCAGTGGGCACTGAGTGGCGCTGGAAAATGGACCCAGCTGAGAAGATTATTCAAGAGGCCATGGAGAACCACAGGAACATGATTCGCCAGTTCAGAGGTGTTCCAGGTGTTCGTCCTGAGCGTTTTGAAGAGGGCCTCACCGTGAAGCACTGTGCTCTGTCTCTGGTGGGTGAACCGATTATGTATCCTGAGATCAACTCCTTCCTTAAACTACTCCACCAGCAGAACATATCCAGCTTTTTGGTCACCAACGCCCAATTTCCTGAAGAGATCAGgaGTCTCGTGCCTGTTACTCAACTTTATGTCAGCGTTGATGCCAGCACCAAGGACAGTCTGAAGAAAATCGACCGTCCCCTCTTCAAAGACTTCTGGCAGCGCTTCTTGGACAGTCTCAGAGCTCTCGGTGAAAAGCAACAGCGTACGGTCTACAGACTGACCCTGGTGAAGGCCTGGAATGTGGATGAGCTGAAGGCCTACGCGGATCTCATCGCCCTTGGCCAGCCAGATTTCATCGAGGTCAAGGGAGTGACGTATTGTGGCGAGAGCTCAGCCAGTAGCCTGACCATGGCCAATGTACCCTGGCATGAGGAGGTCATCTACTTCGTGCAGCAACTAGCCAACCTGCTGCCAGACTATGAAATTGCCTGCGAACACGAGCATTCCAACTGTCTGTTACTCGCAAACCACAAGTTCAAAGTTGATGGAGAGTGGTGGACATGGATTGACTATGAGCGCTTTCAGGAGCTCATTCAGCAATATGAAGAGAGCGGAGGCACCAAGAACTTCTCAGCAATGGACTATATGGCTAAGACCCCAAGCTGGGCCGTTTTTGGGGCCGGAGAGAGGGGTTTTGACCCCACAGACACACGCTTCCAGAGAAAGAACAAGACCAAAGATATATCAGGGTGTTGACAATACCGTTGCCTTCCTAGTTTATGTCTGTATAGGaatgtgtatttttaatgttCGGGATAGATCAGCTGATCGACAGTGTCCACAATTaagatttatgtttttattactttatccAACGTTCGCTTTTGTGCTCTGAGACTGGCCTTAGGGATGCATTTCATGCAAATGTAAAAGTAATCTCTTGCAGACTCTCTTTTTCATGTCGTTTTAATGGATGTTAACTTTTGTTTTTGGTTGTAACCATgctaataaacaatttaatttccAA
>TCONS_00017936
ATGCAGCCGTAAAGTTAGCCCGTTATTTATATCTGAGACGTATGAAGTTAAATCTTTGTCTGGttattgtaaaacatttatttactagACTGTGTTGATGGAGAGAGTACATGAGATGCTGTTTTTATCGGTGTTGTCGGGTTTGGTGTGTTCTGCAGTCGGCGCTGAGATGTCAGGTGTTGTTCTGACAGGAACTGTCCTTTCTCATTCTCATTCACAGACACCACACCAACCCAGTGGGCACTGAGTGGCGCTGGAAAATGGACCCAGCTGAGAAGATTATTCAAGAGGCCATGGAGAACCACAGGAACATGATTCGCCAGTTCAGAGGTGTTCCAGGTGTTCGTCCTGAGCGTTTTGAAGAGGGCCTCACCGTGAAGCACTGTGCTCTGTCTCTGGTGGGTGAACCGATTATGTATCCTGAGATCAACTCCTTCCTTAAACTACTCCACCAGCAGAACATATCCAGCTTTTTGGTCACCAACGCCCAATTTCCTGAAGAGATCAGgaGTCTCGTGCCTGTTACTCAACTTTATGTCAGCGTTGATGCCA

Function

symbol description
tyw1 Predicted to enable several functions, including 4 iron, 4 sulfur cluster binding activity; FMN binding activity; and tRNA-4-demethylwyosine synthase activity. Predicted to be involved in wybutosine biosynthetic process. Predicted to act upstream of or within tRNA processing. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to several human genes including TYW1 (tRNA-yW synthesizing protein 1 homolog).

GO:

id name namespace
GO:0031591 wybutosine biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0008033 tRNA processing biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0046872 metal ion binding molecular_function
GO:0102521 tRNA-4-demethylwyosine synthase activity molecular_function
GO:0010181 FMN binding molecular_function
GO:0051536 iron-sulfur cluster binding molecular_function
GO:0016829 lyase activity molecular_function
GO:0051539 4 iron, 4 sulfur cluster binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0003824 catalytic activity molecular_function

KEGG:

id description
ko03016 Transfer RNA biogenesis

ZFIN:

id description
ZDB-GENE-060929-688 Predicted to enable several functions, including 4 iron, 4 sulfur cluster binding activity; FMN binding activity; and tRNA-4-demethylwyosine synthase activity. Predicted to be involved in wybutosine biosynthetic process. Predicted to act upstream of or within tRNA processing. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to several human genes including TYW1 (tRNA-yW synthesizing protein 1 homolog).

Ensembl:

ensembl_id ENSDARG00000062987

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00017935 False 2633 mRNA 0.48 16 16739160 16872600
TCONS_00017936 True 552 nonsense_mediated_decay 0.47 4 16794111 16872600

Neighbor

gene id symbol gene type direction distance location
XLOC_009106 caln1 coding downstream 34743 16564692 ~ 16704417 (-)
XLOC_009107 BX649487.1 coding downstream 41244 16697515 ~ 16697916 (-)
XLOC_009105 NA coding downstream 183987 16554382 ~ 16555173 (-)
XLOC_009104 fam222bb coding downstream 354976 16377263 ~ 16384184 (-)
XLOC_009103 txndc17 coding downstream 406145 16328450 ~ 16333015 (-)
XLOC_009109 TMEM120A coding upstream 1090 16873690 ~ 16884912 (-)
XLOC_009110 BX571762.1 coding upstream 28302 16900902 ~ 16908130 (-)
XLOC_009111 hip1 coding upstream 62790 16935390 ~ 17025212 (-)
XLOC_009112 lgals17 coding upstream 187022 17059622 ~ 17074393 (-)
XLOC_009113 mos coding upstream 225751 17098351 ~ 17099560 (-)
XLOC_009093 NA non-coding downstream 1027987 15708065 ~ 15711173 (-)
XLOC_009092 NA non-coding downstream 1064008 15669244 ~ 15675152 (-)
XLOC_009091 NA non-coding downstream 1230767 15496101 ~ 15508393 (-)
XLOC_009114 NA non-coding upstream 249812 17122412 ~ 17125772 (-)
XLOC_009119 CU861501.1 non-coding upstream 341462 17214062 ~ 17220226 (-)
XLOC_009120 NA non-coding upstream 362265 17234865 ~ 17252051 (-)
XLOC_009121 NA non-coding upstream 406953 17279553 ~ 17285143 (-)

Expression


Co-expression Network