XLOC_009214 (hmbsb)


Basic Information

Item Value
gene id XLOC_009214
gene name hmbsb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 23511407 ~ 23529945 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00018120
AAGGAAGTCAAGAACCTGTAACATACGAGAATGACATTTGTTCCACtttaatattttcataataatGAATGCGAAGCTACGGCAGTTTTAACAAGATTAGCACTAAATATCGCTAAATAATTTATCTTGAATAATGTCGGAAAAGACAAACCTCCagGACAGTGATGGAAGAGTCAGCAGGGTGATCCGTGTTGGCACCAGAAAAAGCCAGCTGGCTCGGATCCAGACAGACAGTGTCGTGGAGAAGCTCAAGGAGTTATACCCTGATGTTCTTTTTGAAATTGTGGCCATGTCAACAACTGGAGATAAAATACTAGACACAGCTTTATCCAAAATCGGAGAAAAAAGCCTCTTCACAAAGGAACTGGAAAATGCTTTGGAAAAAAATGAAGTAGACCTGGTCGTGCACTCTTTGAAAGACTTGCCAACAGTTCTTCCGGGGGGCTTCACTATAGGAGCTGTGTTGAAACGAGAAAACCCCCATGATGCTGTTGTGTTGCACCCCAAAAATAAAGGCAAACGTCTGGACTCTCTTTCCAACAAGAGCGTAATAGGCACCAGTTCTCTTCGCCGAGCTGCACAGCTGAAGAAAAGATTCCCTCACCTGGAATTTAAAGACATTAGAGGAAATCTCAACACTCGTCTGAAGAAGCTGGATGAGAACAATGACTTTTCTGCCATCATATTAGCAGCTGCTGGCTTGAAGAGAATGGGCTGGGAGAACCGCATCAGCCAGATTCTCGGGCCTGAAGACTGCATGTATGCTGTTGGACAGGGTGCTCTGGCAGTCGAGGTCAGGGCTCGAGACCTGGACATCCTGGAGATGGTGTCAGTTTTGAATGATTCAGACACTGCGTTGAGCTGCATTGCAGAAAGAGCGTTTCTCAAACACCTGGAAGGGGGATGCAGTGTTCCAGTCGCTGTTCACTCTGAAGTGAAGAATTCACAGCTCTACTTGACTGGAGCGGTGTACAGTCTTGATGGCTCAGACAGTCTGAAGGAGACCATGCAGACCAGCTTCAACCCTGACACACAGGCTGAGGAGCAGGAGAAGGTTGATGAGAAGGTCCAGCGTTTGGGAATCACTGCATTAAAAGTGCCAGAGGCAGCTCAGGATGCCGCAATGAAGTTAGGCGTGGACCTCGGAAATCTGCTGCTCAGCAAAGGAGCCAAAGAGATACTGACTGTAGCCAGACAGCTCAATGACGCGCGATAGGTAGCCTACTATACATAAAAGACCATATGTGTGGCTGGAGACACACCAGCCTATACAGAAGTATTTTTATAAACGAAGATTAATGTGCCATAGATGGCGTATTTAAGATATTAGTTTACAACTTTGCCTTGTATTAGTTTATTTACAGTTAACTTATTCATGTCATTGTTTACTTGcttgtgtcattccaaacccaCTAGAGTTTTGTTCATCTTCactcaaatgaagatatttgttataaaaattttatatttatgtcaTTAACTAAAAGTCTATTCATCCAAAACTGTTCATTTGTTCATCTTAAAAAGTAATTATGTCTCATCAGAAGTGTTGGATTAAACCGCTTaattcatatggatttacttttgAATCTCTTGACTAACGGTTTGAAGCGTTTAGGTTTTGGGTGAATAGACTTTCAATAGAGTGACAGGATTTCTTGGTTTGAGAATGAACAATTTTCTTACAGATTTTGGAACCTCATAAGTGTGAGTAAAAGATGACTGCCTTTTCAGTTCAGGCCAAACAAACCCTTTCAACAGGATTGCATGTATGATCATAATAACAATGCAAAACTAATGAAGAATAACACAGGGACTGGGATACATGAAAATCATCTGCATTACATAGAGCTAATGTCCTGTTAGCTCTTATATGAAGCCATGAACACACAATCATGCCTTTTAATATGGTGTGTGTTGTACATAAACACATGCTTACACATTTGAAACTTGAATTATTCTGGGATCTACATTTCCTGAGGCTGCTTGAGATTTCATATGCCGTTTATCTTCCCTGTGGTTATATATACTTGTAAAGATGTAAAGCAGAATGACCTGTGTAAACCACTACAGAAGTTTTGTGTAGATTGGGTCGGCTGTTTTATGCGCAGATAAAAATTGTAATGAATtagatttaattgaaatgttttcatttcagACATTTACCATTCTATGTTATGCCTTTGTTACATATCACTAATAGTCGAATCATCAGTGTGATTGTGAAGAGTCTAACATCAGTGcctataaatttaaaatattgcctCAGCAAATCTGCCTTATGAGCTCTGATGGAGTTTATATGCATCGGCTTATCTTTCTCATTCGTTCCATTTAAAGTAATCAaggcatttttaattatttatgtgttATTATGCTGGAGAACCTCTTGAATGAGGAATTATGATAAAGCTAAGCCAGTATTCATTTCTTGTGATATTCTGGACcatttttttaatgtgatttagaGTCATAGTTGAACTAATTCAATATGAGCATATGCAAGATTTTAAGGATGTTCTGAAATGGATACATttagtatttacattttagtgtAGTATTATTGATAGCATTGAAATAGCTTGAAATGGGCCGCTGACATTTACATGAGATGGTACAGTTTGTACAAATTCAGAGCAGATTTGTTTGCTTTAACTGACTGTACTTGCCTGTCCTAAATAAATCAAGCTATGTAAATGCAA
>TCONS_00018121
tcTGAATACTTTTCACAAGATGCTTTGAATAGCTCTGTTTTTCAAGCTACATTATCTGACAATGGGGACAGTGATGGAAGAGTCAGCAGGGTGATCCGTGTTGGCACCAGAAAAAGCCAGCTGGCTCGGATCCAGACAGACAGTGTCGTGGAGAAGCTCAAGGAGTTATACCCTGATGTTCTTTTTGAAATTGTGGCCATGTCAACAACTGGAGATAAAATACTAGACACAGCTTTATCCAAAATCGGAGAAAAAAGCCTCTTCACAAAGGAACTGGAAAATGCTTTGGAAAAAAATGAAGTAGACCTGGTCGTGCACTCTTTGAAAGACTTGCCAACAGTTCTTCCGGGGGGCTTCACTATAGGAGCTGTGTTGAAACGAGAAAACCCCCATGATGCTGTTGTGTTGCACCCCAAAAATAAAGGCAAACGTCTGGACTCTCTTTCCAACAAGAGCGTAATAGGCACCAGTTCTCTTCGCCGAGCTGCACAGCTGAAGAAAAGATTCCCTCACCTGGAATTTAAAGACATTAGAGGAAATCTCAACACTCGTCTGAAGAAGCTGGATGAGAACAATGACTTTTCTGCCATCATATTAGCAGCTGCTGGCTTGAAGAGAATGGGCTGGGAGAACCGCATCAGCCAGATTCTCGGGCCTGAAGACTGCATGTATGCTGTTGGACAGGGTGCTCTGGCAGTCGAGGTCAGGGCTCGAGACCTGGACATCCTGGAGATGGTGTCAGTTTTGAATGATTCAGACACTGCGTTGAGCTGCATTGCAGAAAGAGCGTTTCTCAAACACCTGGAAGGGGGATGCAGTGTTCCAGTCGCTGTTCACTCTGAAGTGAAGAATTCACAG
>TCONS_00018122
ATTGCTTTCTCTTCCTGAAAGTATCTGAACTTTAGCTCAGTTCTCTACAGATATGGCAGATGGACCTTATAAATATGCCAGGGACAGTGATGGAAGAGTCAGCAGGGTGATCCGTGTTGGCACCAGAAAAAGCCAGCTGGCTCGGATCCAGACAGACAGTGTCGTGGAGAAGCTCAAGGAGTTATACCCTGATGTTCTTTTTGAAATTGTGGCCATGTCAACAACTGGAGATAAAATACTAGACACAGCTTTATCCAAAATCGGAGAAAAAAGCCTCTTCACAAAGGAACTGGAAAATGCTTTGGAAAAAAATGAAGTAGACCTGGTCGTGCACTCTTTGAAAGACTTGCCAACAGTTCTTCCGGGGGGCTTCACTATAGGAGCTGTGTTGAAACGAGAAAACCCCCATGATGCTGTTGTGTTGCACCCCAAAAATAAAGGCAAACGTCTGGACTCTCTTTCCAACAAGAGCGTAATAGGCACCAGTTCTCTTCGCCGAGCTGCACAGCTGAAGAAAAGATTCCCTCACCTGGAATTTAAAGACATTAGAGGAAATCTCAACACTCGTCTGAAGAAGCTGGATGAGAACAATGACTTTTCTGCCATCATATTAGCAGCTGCTGGCTTGAAGAGAATGGGCTGGGAGAACCGCATCAGCCAGATTCTCGGGCCTGAAGACTGCATGTATGCTGTTGGACAGGGTGCTCTGGCAGTCGAGGTCAGGGCTCGAGACCTGGACATCCTG

Function

symbol description
hmbsb Predicted to enable hydroxymethylbilane synthase activity. Predicted to be involved in heme biosynthetic process. Predicted to act upstream of or within peptidyl-pyrromethane cofactor linkage and porphyrin-containing compound biosynthetic process. Predicted to be active in cytoplasm. Is expressed in hematopoietic system; mesoderm; and post-vent region. Human ortholog(s) of this gene implicated in acute intermittent porphyria and sickle cell anemia. Orthologous to human HMBS (hydroxymethylbilane synthase).

GO:

id name namespace
GO:0018160 peptidyl-pyrromethane cofactor linkage biological_process
GO:0033014 tetrapyrrole biosynthetic process biological_process
GO:0006783 heme biosynthetic process biological_process
GO:0005737 cytoplasm cellular_component
GO:0004418 hydroxymethylbilane synthase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050522-491 Predicted to enable hydroxymethylbilane synthase activity. Predicted to be involved in heme biosynthetic process. Predicted to act upstream of or within peptidyl-pyrromethane cofactor linkage and porphyrin-containing compound biosynthetic process. Predicted to be active in cytoplasm. Is expressed in hematopoietic system; mesoderm; and post-vent region. Human ortholog(s) of this gene implicated in acute intermittent porphyria and sickle cell anemia. Orthologous to human HMBS (hydroxymethylbilane synthase).

Ensembl:

ensembl_id ENSDARG00000055991

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00018120 False 2702 mRNA 0.39 14 23511407 23523222
TCONS_00018121 False 858 mRNA 0.47 12 23514732 23529945
TCONS_00018122 True 745 mRNA 0.47 11 23516172 23522653

Neighbor

gene id symbol gene type direction distance location
XLOC_009213 abcg4b coding downstream 3193 23487730 ~ 23508214 (-)
XLOC_009212 nlrx1 coding downstream 25655 23468025 ~ 23485752 (-)
XLOC_009211 pdzd3a coding downstream 43657 23452862 ~ 23467750 (-)
XLOC_009210 ube4a coding downstream 67470 23423672 ~ 23443937 (-)
XLOC_009209 kmt2a coding downstream 91237 23382199 ~ 23420170 (-)
XLOC_009215 si:dkey-182i3.11 coding upstream 14486 23544431 ~ 23546452 (-)
XLOC_009216 ckmb coding upstream 113773 23643718 ~ 23647078 (-)
XLOC_009217 ercc2 coding upstream 150073 23680018 ~ 23692359 (-)
XLOC_009218 zgc:154093 coding upstream 163569 23693514 ~ 23699737 (-)
XLOC_009219 zc3h4 coding upstream 179384 23709329 ~ 23721618 (-)
XLOC_009205 NA non-coding downstream 357147 23144954 ~ 23154260 (-)
XLOC_009204 BX572079.1 non-coding downstream 556275 22955017 ~ 22955132 (-)
XLOC_009203 CR388121.1 non-coding downstream 790526 22720765 ~ 22720881 (-)
XLOC_009202 NA non-coding downstream 916522 22588504 ~ 22594885 (-)
XLOC_009200 CR936967.1 non-coding downstream 1250410 22260881 ~ 22260997 (-)
XLOC_009227 CU313324.1 non-coding upstream 629008 24158953 ~ 24159067 (-)
XLOC_009228 NA non-coding upstream 1031876 24561821 ~ 24563061 (-)
XLOC_009230 NA non-coding upstream 1062380 24592325 ~ 24618905 (-)
XLOC_009234 NA non-coding upstream 1371606 24901551 ~ 24927093 (-)
XLOC_009236 NA non-coding upstream 1438147 24968092 ~ 24974112 (-)

Expression


Co-expression Network