Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_009403 |
| gene name | mecom |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007126.7 |
| NCBI id | CM002899.2 |
| chromosome length | 48040578 |
| location | 35372907 ~ 35410860 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| mecom | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic cranial skeleton morphogenesis; endothelial to hematopoietic transition; and pronephric nephron development. Predicted to be active in nucleus. Is expressed in several structures, including brain; dorsal aorta; head; mesoderm; and pronephros. Human ortholog(s) of this gene implicated in myeloid neoplasm. Orthologous to human MECOM (MDS1 and EVI1 complex locus). |
| id | name | namespace |
|---|---|---|
| GO:0035776 | pronephric proximal tubule development | biological_process |
| GO:0035777 | pronephric distal tubule development | biological_process |
| GO:0006357 | regulation of transcription by RNA polymerase II | biological_process |
| GO:0048793 | pronephros development | biological_process |
| GO:0072196 | proximal/distal pattern formation involved in pronephric nephron development | biological_process |
| GO:1903251 | multi-ciliated epithelial cell differentiation | biological_process |
| GO:0008593 | regulation of Notch signaling pathway | biological_process |
| GO:0048701 | embryonic cranial skeleton morphogenesis | biological_process |
| GO:0048702 | embryonic neurocranium morphogenesis | biological_process |
| GO:0098508 | endothelial to hematopoietic transition | biological_process |
| GO:0048703 | embryonic viscerocranium morphogenesis | biological_process |
| GO:0005634 | nucleus | cellular_component |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | molecular_function |
| GO:0046872 | metal ion binding | molecular_function |
| GO:0003676 | nucleic acid binding | molecular_function |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | molecular_function |
| id | description |
|---|---|
| ko00310 | Lysine degradation |
| ko04010 | MAPK signaling pathway |
| ko05200 | Pathways in cancer |
| ko05220 | Chronic myeloid leukemia |
| ko03000 | Transcription factors |
| ko03036 | Chromosome and associated proteins |
| id | description |
|---|---|
| ZDB-GENE-050208-123 | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic cranial skeleton morphogenesis; endothelial to hematopoietic transition; and pronephric nephron development. Predicted to be active in nucleus. Is expressed in several structures, including brain; dorsal aorta; head; mesoderm; and pronephros. Human ortholog(s) of this gene implicated in myeloid neoplasm. Orthologous to human MECOM (MDS1 and EVI1 complex locus). |
| ensembl_id | ENSDARG00000060808 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00018494 | False | 2715 | mRNA | 0.52 | 11 | 35372907 | 35406564 |
| TCONS_00018495 | True | 579 | mRNA | 0.54 | 5 | 35403080 | 35410860 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_009402 | mff | coding | downstream | 120359 | 35226673 ~ 35252548 (-) |
| XLOC_009401 | mrpl44 | coding | downstream | 148426 | 35214546 ~ 35224481 (-) |
| XLOC_009400 | agfg1a | coding | downstream | 160445 | 35156414 ~ 35212462 (-) |
| XLOC_009399 | si:ch211-272b8.7 | coding | downstream | 237989 | 35130621 ~ 35134918 (-) |
| XLOC_009398 | bloc1s3 | coding | downstream | 246275 | 35036368 ~ 35126632 (-) |
| XLOC_009404 | CR848683.2 | coding | upstream | 3606 | 35414466 ~ 35661368 (-) |
| XLOC_009405 | CR848683.1 | coding | upstream | 29880 | 35440740 ~ 35468800 (-) |
| XLOC_009406 | NA | coding | upstream | 203374 | 35614234 ~ 35675985 (-) |
| XLOC_009407 | NA | coding | upstream | 350821 | 35761681 ~ 35886373 (-) |
| XLOC_009408 | CR854907.1 | coding | upstream | 369180 | 35780040 ~ 35780805 (-) |
| XLOC_009389 | NA | non-coding | downstream | 765501 | 34602522 ~ 34607406 (-) |
| XLOC_009383 | FP017158.1 | non-coding | downstream | 1093372 | 34279421 ~ 34279535 (-) |
| XLOC_009376 | CR855379.2 | non-coding | downstream | 1485240 | 33868661 ~ 33887667 (-) |
| XLOC_009377 | NA | non-coding | downstream | 1495576 | 33869579 ~ 33877331 (-) |
| XLOC_009371 | NA | non-coding | downstream | 1691229 | 33665924 ~ 33681678 (-) |
