CI01000049_00502964_00505708 (LIG4)


Basic Information

Item Value
gene id CI01000049_00502964_00505708
gene name LIG4
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000049
NCBI id null
chromosome length 9665442
location 502964 ~ 505811 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000049_00502964_00505708.mRNA
GTGTCCTCTGCAATGATGGAAGGAGCCTCAAAAAGTGATACCACACCACAGGCCTCTGTTGCTGCACAAGTTCCGTTCATCCACCTCTGCACAGTTCTGGAGAAGATTCAAAAGACAAAACTACGACCAGACAAAGGCAAAATCCTAAAGGAGTTTATAGATTCATGGAGGAATTTTCACGCAGCACTTCACAAGGACAATTCCAACACAACAGATTCATTTTACGCAGCAATGCGTCTCATTGTGCCTCCATTTGAGCGAGAGCGAATGGCTTACGGTATAAAAGAGAACATGCTTGCCAGATTGTATATTGAGGTTTTAGGCTTACCTAAAAATGGTCCTGAGGCAAACAAACTTCTAAATTACAGAGCTCCAACCACATCTCAAGGAGAAGCAGGTGACTTTGCCCTTACAGCCTACTTTGTCCTGAAAAAAAGGTGCACAAGTCAGGGGAATTTAAGCATTAAGGAAGTCAATGACTTCTTAGATTCTGTAGCTATCAACAATGCCAGCAAACAGAAGGATCAAGTGAAGAAAAGCCTTTTGCATCTAATAACTCAGAGCTCAGCTTTGGAACAGAAGTGGCTCATTCGAATGATCCTCAAGGACATGAAACTTGGCATTAGCAAGGAGACAATTCTTCAAGTTTTCCATCCAGATGCAACAGAACTCTACAATGTCACCACAGATCTAAATAAAGTGTGCCTACAACTTCATGATCCATCTGTGTCCCTCAGTGAGGTCTCCATTGATCTGTTTTCTGCGTTTAAACCAATGCTGGCTGCTGTTGCCAACATCAGACAGATAGAGAAGCAAATGGGCAACCGGCCATTCTATATTGAGACAAAGCTCGATGGTGAACGCATTCAGCTGCACAAAGCTGGAGATGTTTACAAATATTATACAAGGAACTCTTATGAGTACACACAACAGTTTGGGGCCTCTCCACTAGAGGGCTCCCTCACGCCATACATTCACAATGTCTTCAAACCTCATGTGGTGAACTGCATACTGGATGGAGAGATGATGGCTTATAACCCTAAAACTGAGACCTTCATGCAGAAGGGCAGTAAATTTGATATTAAAAAGCTGATGGATGACTCTGAGTTGCAAACCTGCTTTTGCGTATTTGATGTCTTGTTAGTGAACAATCAGAAGTTTGGAAATGAACCTCTCAAGAAGCGCTACGAAACTCTTGAGACTGTCTTCACCCCCATCAAAGGCCGTATCCAGCTGGTCACTAATTCTGAAGGCAAAACCATGCAAGAAGTAGTGAATTTCCTCAACGAAGCCATTGACAATCTGGAAGAGGGGATTATGATTAAGGATCCCATGTCCATCTACAAACCGGATAAACGTGGTGAAGGATGGCTGAAAATTAAGCCTGAATATGTGGACGGTCTGATGGATGAACTCGATCTGCTGATAGTGGGAGGCTACTGGGGTAAAGGTAGGAGAAGCGGGATGCTCTCTCATTTTCTCTGTGCGGTAGCAGAGGTGCCAAGTCCTGGAGAGAAGCCTACAGTATTCCACACCCTCTGCCGCATTGGATCAGGCTACACTATGAAAGAACTGTACGATCTTGGTCTGAAGTTAGCCAAACATTGGAAAGTTTACAACAAAAATAATCCTCCAGCGGCCATTTTGTGTGGAACAGAGAAACCAGAGGTTTACATAGAACCACGCAACTCAGTCATCTTACAGGTCAAAGCGGCAGAGATCGTTTCTAGTGATATGTATAAAACCAACTGCACATTGCGTTTCCCCAGAATAGAAAGAATCAGAGAAGACAAAGAGTGGCATCAGTGCATGACCTTGACCGACCTGAGCCAGTTCCGCTCCAGGGCTTCTGGGAAGCTGGCATCCAGACATCTGCACATCCAAGAGGACCAGCCTGAAAAAAAGAAGCGCAAATTTGTAGCCAAGCCCAAGAAGACCATAGGAGTCATTAGCCACTTTAAATCTCAGGATTTATCAGCAGTCGCCAAAGAGATGGATATGTTTGAAGATGTTGAGTTTTGCGTGATAAATGGCGACGACGAACATTCCAAGGCAGATCTTGAGAAAGGTGTGGCCCGTTGTGGAGGCATTGTTGTGCAAAACCCTGGAAAAGACACATACTGTGTGATTGCAGCTGTGCAGAACATGAGAGTGAAGAACCTTATCTCTTCAGACCAGAATGATGTGGTGTGGGCTGCTTGGCTTCTGGAGTGTCTGGAAAATAAGCAGGTTATACCATGGCAACCACGTCACATGATCCATATGTCACCCTCCACAAGGGACCACTTCGCTAAAGAGTATGATCAGTATGGGGACAGTTATTACGTTGACACGGATGAACAGCAGCTGATGGAAGTCTTTGAAAGGATTGGCCCCACACAAGCTAAATGTCCGTCTGTGGCTCGGGTAGAAGCAGACAATGCCTGGGATGACTTGCCCACTAGCATTTTTAGGCCTTACAGTGCATACTTTGACCGGTGTGCTGACTTAGGAGATCCGAAATCCATTATCCGGGGTACATGTTTGGACACACGTGCCTTAGAATTCCGATTTCATGGTGGTACAGTTGTGGAAAAACTGAAGGAAGGAATCTCACATGTCATAGTAGAAGGTGAGAGAAGGGCTCTGGACTTAAAGACACTGAGGCGACTTTATACTAAGAAGTTCAAAATTGTTCGGGAATCTTGGGTGACCGATTCCATCAAAGCAGGCCATGTAGAGGATGAGATTGACTACCTTATATAACGATGACCGCTACTACACAAAATGTTAAAACACTGAAAGATTACAGCATTTTAATACTAGGTGTCATAACCATTACTGTTGCATTAAAGCTAACATTATAAAA

Function

symbol description
lig4 Predicted to enable ATP binding activity; DNA binding activity; and DNA ligase (ATP) activity. Acts upstream of or within double-strand break repair via nonhomologous end joining. Predicted to be part of DNA ligase IV complex and DNA-dependent protein kinase-DNA ligase 4 complex. Human ortholog(s) of this gene implicated in several diseases, including DNA ligase IV deficiency; colorectal cancer; high grade glioma; multiple myeloma; and prostate cancer. Orthologous to human LIG4 (DNA ligase 4).

GO:

id name namespace
GO:0032807 DNA ligase IV complex cellular_component

KEGG:

id description
K10777 LIG4, DNL4; DNA ligase 4

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000049_00502964_00505708.mRNA True 2848 mRNA 0.44 1 502964 505811

Neighbor

gene id symbol gene type direction distance location
CI01000049_00439527_00443722 IRS2A coding upstream 58661 439037 ~ 447286 (+)
CI01000049_00389394_00392865 NA coding upstream 109039 389394 ~ 393925 (+)
CI01000049_00379082_00388164 CARS2 coding upstream 114554 378973 ~ 388410 (+)
CI01000049_00372677_00374333 UBE2A.L, UBE2A, UBE2B, UBE2AL, BRAFLDRAFT_128294 coding upstream 128055 371789 ~ 374909 (+)
CI01000049_00350921_00371213 NA coding upstream 131674 350028 ~ 371290 (+)
CI01000049_00514310_00583480 FAM155A coding downstream 8499 514310 ~ 583480 (+)
CI01000049_00593358_00626752 NA coding downstream 87166 592977 ~ 626925 (+)
CI01000049_00814236_00838530 RAPH1B, RAPH1 coding downstream 308425 814236 ~ 838530 (+)
CI01000049_00854473_00859727 CPB2 coding downstream 348662 854473 ~ 859858 (+)
CI01000049_00864358_00887502 ZC3H13 coding downstream 358547 864358 ~ 887845 (+)
G205408 NA non-coding upstream 99935 402539 ~ 403029 (+)
G205327 NA non-coding upstream 102801 398132 ~ 400163 (+)
G205371 NA non-coding upstream 295508 207207 ~ 207456 (+)
G205370 NA non-coding upstream 295803 206954 ~ 207161 (+)
G205752 NA non-coding downstream 105750 611561 ~ 611811 (+)
G205768 NA non-coding downstream 126906 632717 ~ 633195 (+)
G205774 NA non-coding downstream 133970 639781 ~ 640252 (+)
G205775 NA non-coding downstream 135099 640910 ~ 641239 (+)
G205776 NA non-coding downstream 135624 641435 ~ 641777 (+)
CI01000049_01840330_01843844 FGF8B other downstream 1334004 1839815 ~ 1844077 (+)
G207888 NA other downstream 3118191 3624002 ~ 3624311 (+)
G208074 NA other downstream 3371585 3877396 ~ 3882211 (+)
CI01000049_04473766_04475768 GM10043, LSM6, SNRPF, BRAFLDRAFT_125735 other downstream 3967714 4473662 ~ 4476270 (+)
G209660 NA other downstream 6372322 6878133 ~ 6882030 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_000344 lig4 coding NC_007112.7 CM002885.2 29267841 ~ 29271473 (+)