XLOC_012396 (gnmt)


Basic Information

Item Value
gene id XLOC_012396
gene name gnmt
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007128.7
NCBI id CM002901.2
chromosome length 53461100
location 48920799 ~ 48936123 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00024329
TCTACATTTTAATGTTTGCCATATTTTTCAGAAAGTCTTTAAAAAATGAATCGTCAGTTACTCACTTAAAAAATCTGATGAAACACAGGCGGGGGGTGTCTCTTCTAGCCTGATGACGTCGTCATACGTCTCGGCCAATAGCAATGTAGGCGTGAGCGCTTAGGCACGTCCGATTGGTCAAAAGTTGACGTTTCAACACTGACTGATATAAATGTCAACATAGAACTTGTAAGCATGACAAAGACCCAACACTTGTAAGAACATAACTAACGGGACATTCATTATTAAAGATCCCATAGAACAATAAAGAGCGGTGCGATAATTCAGTATGGTGGACAGTGTTTACCGTACACGCTCTCTCGGTGTTGGTGCTGTTGGACTTCCTGATCAGTATGCCGACGGCAAAGCAGCGAAAGTGTGGCAGCTGTACATCGGAGACACTCGGAGCAGGACAGAAGAGTACAAGAGCTGGGTGCTGGCCCTACTCAGGAAGCATGGGGTTCAGAGGGTGCTGGATGTAGCCTGCGGCACAGGGGTGGATTCCATCATGTTGGTAGAAGAGGGATTCAGCGTGGTTAGTGTGGATGCTAGTGATAAAATGCTGAAATATGCTCTTAAAGAGAGATGGGAGAGAAGAAAAGAGACAGCTTTTGATAACTGGGTGATTGAGGAGGCCAACTGGCTAACATTACCAGAAGATGTTAAGAAGCCTGGAGATGGCTTTGATGCTGTAATCTGTCTTGGgaactcatttgctcatttacCAGATTTTAAAGGGGACCAAAGTGATCAGAAGCTCGCCTTGCAAAACATAGGCAGCATGGTGAAACCTGGAGGGATCCTAATCATTGACCACCGCAACTATGATTACATCATTGAGACTGGCCAAGTGCCTCAAGGAAAGAATATTTACTATAAGAGTGACCTGAAACAGGACATCTCTACCTCAGTACTGTGGGTTAATAGCAAGCCTCACATGATCACACTGGACTACACACTGGTGCTGCCTCAACCAGAGGGAGCTCAGACTCCGCCTGACACAAGTAAATTCCGCCTGTCATACTACCCCCATCGTGTGGAGAATTTTAAGGAGATATTAAAAGCAGCGTTTTGGGGAAAATGCGAGCACAATGTATATGCCGACTTCAAGCAATACACTGCAGGAGGAGAGCCACCCTGTTATTTCATCCATGTTGTTAAAAAGACAGCTTAATGCCACTTTAAATCTGCAATTTCATTTCATCTTAACATGGTCTTGTCTGTGTAAAGAAAATCTACTAAGGTAACACATCTACAGGTTTTTTATAAAACTTTGCcatattgttttaaaagtaaatattgaTTTTGTGATTTCACATTCACAGTTGTTTCCAATTTGAACTGGCCTACATGCTCttcattttattgatttattcatacTTTACTTCaatgatgttttatttaatctttcATAGTATACATTCTTATTCTTGATGCTTGTTCTTTATTGAATGCTGTTTTAAAACCTGCAccaaaaagtaaagtaaatgtaCTACTTTGTGTCTGTACTTCGTGTctgtattatatttacatttctaCATGAGTTGGCTTAAATGGAGCTTTAAACTTCTTAATGGTTGACACAGCACATCCCTAATATTTAGACTAAAGGCTTGTACAAATGaggcttttcgtttgcgtttatcgtcaacgttttacgagacgtttttccgggTTCAAAcaaagcgattttcactggcgtcgagcagaagaatACGCAAAAttactccttgacgttagatggcgctacacaactttaagcttctaaCATCTGCTTATAACACAAaaagaggaagttcacacgtttgttgttaaagttactggtgactcaaacaagcatggatggttcaattAGCAGCTCTAGCTCTAGCGATGAAAAGATGATTATAGTCCAGTGCAATAAGCATATTGCCTTCAAAacattcatatcgcctctgggcatcttcttcaatgtgcactCGCATTCACAGTtatgcgcttgagcgcctccaagtgctgtttactttaactttagcagctccgtgcacatgaacaaaagtgctgATCTGATTGGTCGGGAAGGTTTTGACGTGacgcatcaaaacaaaaaagcgAGCAGGAGGCGTTTCAttaaaaatgacgcttttacgcctgccgttttgcacgttggtgtgcacaatcacatttgcgccttttatttagtcacgaggtgtTAAACGTCGAAGGGATACGTGAGCAAAAACTGTCTCGGTGTACATGGGTCTTTACTTATCTACTTCTATAACATGTTGGAATATCATGCCAACTCCATGGgttttcaataagaaaaggtctggagagggttttcttcaatgccaaaaatattagtaatttattaaatgcaaatgaataatttgatgacagagctctggaTTATATTatcccaatgcaatacaagaattacattcaagaggttcacatacatttccctgactccagcatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatata

Function

symbol description
gnmt Predicted to enable cation binding activity; glycine N-methyltransferase activity; and identical protein binding activity. Predicted to be involved in several processes, including alpha-amino acid metabolic process; protein homotetramerization; and regulation of gluconeogenesis. Predicted to act upstream of or within methylation. Predicted to be active in cytosol. Is expressed in spinal cord. Human ortholog(s) of this gene implicated in glycine N-methyltransferase deficiency. Orthologous to human GNMT (glycine N-methyltransferase).

GO:

id name namespace
GO:0006111 regulation of gluconeogenesis biological_process
GO:1901052 sarcosine metabolic process biological_process
GO:0006730 one-carbon metabolic process biological_process
GO:0051289 protein homotetramerization biological_process
GO:0032259 methylation biological_process
GO:0046498 S-adenosylhomocysteine metabolic process biological_process
GO:0046500 S-adenosylmethionine metabolic process biological_process
GO:0005829 cytosol cellular_component
GO:0016740 transferase activity molecular_function
GO:0008168 methyltransferase activity molecular_function
GO:0042802 identical protein binding molecular_function
GO:1904047 S-adenosyl-L-methionine binding molecular_function
GO:0017174 glycine N-methyltransferase activity molecular_function
GO:0016594 glycine binding molecular_function

KEGG:

id description
ko00260 Glycine, serine and threonine metabolism

ZFIN:

id description
ZDB-GENE-040227-1 Predicted to enable cation binding activity; glycine N-methyltransferase activity; and identical protein binding activity. Predicted to be involved in several processes, including alpha-amino acid metabolic process; protein homotetramerization; and regulation of gluconeogenesis. Predicted to act upstream of or within methylation. Predicted to be active in cytosol. Is expressed in spinal cord. Human ortholog(s) of this gene implicated in glycine N-methyltransferase deficiency. Orthologous to human GNMT (glycine N-methyltransferase).

Ensembl:

ensembl_id ENSDARG00000006840

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00024329 True 2564 mRNA 0.40 6 48920799 48936123

Neighbor

gene id symbol gene type direction distance location
XLOC_012395 NA coding downstream 1885 48916486 ~ 48918914 (-)
XLOC_012394 lgals8b coding downstream 5372 48906344 ~ 48915427 (-)
XLOC_012393 kif6 coding downstream 115640 48745740 ~ 48805159 (-)
XLOC_012392 kcnk17 coding downstream 177723 48736160 ~ 48743076 (-)
XLOC_012391 kcnk5a coding downstream 214806 48683769 ~ 48705993 (-)
XLOC_012397 si:ch1073-80i24.3 coding upstream 7081 48943204 ~ 48944465 (-)
XLOC_012398 tfb1m coding upstream 284003 49220126 ~ 49280428 (-)
XLOC_012399 CU695076.1 coding upstream 291081 49227204 ~ 49227319 (-)
XLOC_012400 orc3 coding upstream 377381 49313504 ~ 49339681 (-)
XLOC_012401 gpx2 coding upstream 409648 49345771 ~ 49349192 (-)
XLOC_012390 NA non-coding downstream 312652 48607713 ~ 48608147 (-)
XLOC_012389 FP236356.2 non-coding downstream 345442 48574770 ~ 48575357 (-)
XLOC_012388 FP236356.1 non-coding downstream 416470 48486308 ~ 48504329 (-)
XLOC_012387 NA non-coding downstream 436379 48477295 ~ 48484420 (-)
XLOC_012405 CABZ01003476.2 non-coding upstream 515054 49451177 ~ 49451298 (-)
XLOC_012407 NA non-coding upstream 528186 49464309 ~ 49470669 (-)
XLOC_012410 CU929037.3 non-coding upstream 651512 49587635 ~ 49594737 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000311_00368494_00376259 GNMT coding CI01000311 null 368494 ~ 376345 (-)
bowfin (Amia calva) AMCG00004092 gnmt,LOC107748599,LOC107566124 coding CM030121.1 CM030121.1 32937405 ~ 32946916 (+)